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Industrial Hvalsns Digest
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.Injection la rats ia dost* of 0.9 LD^q at greeter produced changes if respiration. la a svndy
o'^ Subacute tenacity ti given daily dotee of 20, 30 or 40 m| per kg. died after U4 day*, *
whereas daily dot*a of 10 mg. per kg. were tolerated lot' 4?-H daye before daub supervened.
The effect was considered to bo cumulative,
" Bull. Hyg.
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734 Characteristics ol Yraco loot Released from Embedded Metal Implants lathe Rabbit.* A. B. F.rautoo, Jr., t 4i. J. Bona Joint ^urg. 44A* *ii (Mar. Whil.
Th* fdi of natal loot ralaaaad by amboddad implant* 6? commonly good lUoyi vti
studied In rabbits. Spactroehamical analyte* ware dona ol tba livarv spleen, kidnap, long,
muscle immediately surrounding the implant, and akaletel muacle from elsewhere in the animal.
Tba object of thie experiment ala to liiaimbat (l) whether loot released from the implant eir*
^dvttd-nitte <body, *t)wfc*s *rr%m ww*o tataia ema trfyw.fctog up ttolmt metal iana.
. and (31 what increase or oacvaaee iaaeoncfncitauons oi Ions occurred oveV n I6*weeb period la V tba tleeuM analysed. VJtpUium, HD staiaieee steely tacoloy, A-296 ste*aUee*teel,F aluminas
. J02vT3`, ti(aniumv tircQaiom^*abd`puron*wekd imbedded in cti* fkeleigl duecles o| alhlportto, a
Wt~qpn al^py ea any on \aimal..*`Thetplssn* wapfCqund to be the.npt- aetav^sUsoI trebeUni
eterhg*. `Thy,other organs, tended tb*ggf rid.of as >arl^4O0?dat*'ln condentratifia. * CobaCt and .
,nickel.warp tba Vno'st active idoa La ^t of their ?resence.in tjie organs. *
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. . , .. J/.Ara. ties. Aasn. Rafereftepe aa4 ftovirat
7J9 Tba Prevention of Manganese Poisoning. J> C. Wyntsr, iae."'Mal, k 8n7t. il. 103*110 ,JUy 1^61).
Manganeee ia etiU a poison, even when the amounts absorbed ara small, A long period of exposure may bring on poisoning wish oifisren: Initial svmptomatology, and it ie ne cessary to be on tba alert to discover u. Analyses of the urine and blood for manganese must be made constantly of workers exposed to this fitment*. It is also important to keep d dstailed record of tba minute quantities contained in tbe air. Tbe results obtained from this study will b* the subject of a later communication.
796 Acute Oral am! Parenteral Toxicity of Fotti Titanate Compounds in tbs Rat. 3. IU Brown and E. Masiromatuo. Ind. Uso. <k Jura. 11. 313004 iJalyTw).
A study of the acute oral and intraperitoneal toxicity of barium titanalb, bismuth-ti-
tanste, calcium titanate. ind lead titanate Was carried out in white rata of the Wlstar^ strain,
each weighing about 23C grams. Tbs acute oral LD*q at these compounds in the rat exceed!
12 g. /kg. The ipfraperitoneal UO)g was found to range from 3.6 g./kg. for lead titanate to
9,1. g./kg. for cslciqm titanate. Repeated dally dosage of 100 mg. of these manatee to a email '
group of rate showed no evidence of cumulative effect over 6 2 w'eek period: ` to gkner.nl, these
compounds are relatively insoluble and chemically Inert. They have a low order of acute oral
and parenteral tonicity to the rat. It l* fU, therefore, ibat tbe 4 manatee studied would prt *
tent Uula Industrial hygiene aasird in ordasar* handling. Occupational exposures would occur
chiefly :v inhalation. Centro: measures should be cased in tbs particular titanate in usei for
example, cue ccnseatratlcn :t Uaa dianate m tbe .air ;i tbe -orris* -mviroaisent mould be
batec ta Ut '.sad ccasect.
Awtnors'summary
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t 737 Corrosive Otitri:is after Pcrmaideh^ds tngssnon. M. Roy, Jr.. M. A. Calonjs and R. Mouscn.
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Mtu. let.
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* A cats corrosive 'jastritie after formaiiohyde Ingestion (240 ml., J7& solution),
I tellsved :a be nhe iscor.d tf its lur.c rtportsd in ^is Aoentan iliomcure it presented. lCray f films takcA befepe tad after ingestion cf formaidsayde are laclcdae. along with a brief comment
* * about ?n a^bste rospcnsiblb icg ccrronvs gasirttls. t '
Actaovat.summary
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