Document qd2MrvEbZXbQeJYe0EZM530kR

FILE NAME: DuPont (DUP) DATE: 1964 Nov 2 DOC#: DUP076 DOCUMENT DESCRIPTION: Letter to MD in Employee Relations Dept from G.J Stopps RE Secondary Effects of Asbestos with Attached Trip Report to Conference on Biological Effects of Asbestos, 1964 Oct C."A. ' B'1.ALON20, .D. ! - 2- November "2, 16A Incidence o f chronic efc. v ln - d is a b ilit y allowances card iovascu lar d ise a se in ; es c - TM s 0^ a a ^ n a a le s 1^ ; " o^ to * e u " s eontinue. to r l M . tho p r o iS -ld ^ b e1!* s e r io u s one fo r the Company. One *?*"*? t ,t h i * p M ilen 1* to Know 11 erployees In the t t a * j u ? t. employees i t doeurented. > ; t ^ { b is^ lfn e pulsonary function position i f , evalu ation the C o B p ^ w o id i b e ^ * filtgnosed in an enployee chronic pulmonary d ise a se i# l ' r*a 7 nft r. . t in i t s ; to s ta te tn a t the ^ ^ " * f " ' X r f e r l e s s n o n e / than would be K X S T i. 1 1 ` lo A ff f ^ n c l. jo u rt " r ^ K U t e * pulnonary fu n ctio n t e s t l n s prosraE can be se t u, a..u >for a t r ia l period of fiv e years. I s h a ll be 6l i to p resent a eonerete proposal along these lin e s . ORIGINAL signed sr G. J. STORPS 1 0. J. Stopps, H .B ..B .S. # C hief, Physiology Section QJS/dyb Enclosure Nove fjM" ORA1-NDUM : J . A. Zapp, J r ^ . Y V 10K: G. J . Stopps J , V ' Kb.j ^ 1? ; * i - -1 \\ v.*/ ' ` -v / TRIP REPORT V Sr,-: wi ivrrr.r.^r . / A, s\ce,s to s cf \o::z:\-o is S 9, 2(5-.and 21, 1964 /s under th e au sp ices o f-th e New York Academy o f S e i^ n c e s^ th e Section of B io lo g ic a l and Medical Sciences -- sacers g_iv en , her. were given oeooie :r.nected v;i ' ,he a s b e s to s #in d u s try in the U nited S ta te s and Canada, whereas Jiere were seven given by re p re s e n ta tiv e s of the asb esto s in a u stry J B rita in and a fu rth e r th re e or fo u r papers were given by persons pnnected w ith the. asb e sto s In d u stry in South A frica. th e p o in t of view o f th e Du Pont Company as a whole, tne nr. i n t e r e s t o f the m eetings was in drawing a tte n tio n to th e f a c t *.at a s b e s tc s is and c o m p licatio n s of a s b e s tc s is have now been bund in p erso n s who would not in th e o rd in ary way come to mind as ling exposed to a s b e s to s ; t h a t i s to say, th ey do n o t work in Ibestcs* m ines, asbestos m ills , or asbestos t e x tile f a c to r ie s . W erlin in g th is r e la tiv e ly wide exposure of persons to aso esto s is the work o f I . J . S e lik o f f , from th e Mt. S in a i H o s p ita l, New r *'k^ ,j who has been * #s*t*u* ^d^ yi*n* 3g. th. e. w.wo*rkers . -i-n-- t--h-_--e-___i-_-n--_s_u. l*a ^t i^o n^ tr a_d^ReAMs Pin lw vork C ity . The in v e s tig a tio n re p o rte d concerned 1522 memcers t the I n te r n a tio n a l A s so c ia tio n o f Heat and F ro st I n s u l a t o r s ar.c io esto s Workers in th e New York-New Je rse y m e tro p o lita n area^. -ne i*udy in c lu d e d every In d iv id u a l who was a member o f t n i s union on ^ fcember p i , 1942, or who Joined by December 31, 1962. Two huncrea Lxty-four men were dead on Jan u ary 1, 1963, and 4p have c .e d s-..ce . Ith d ea th was s tu d ie d . One thousand two hundred f i f t y - e i g n t men s t i l l a liv e and 1117 of th ese were examined. T his re p re se n ts of the population a t r is k . C lin ic a l, ra d io lo g ic a l ana N o n a r y fu n c tio n exam in atio n s were a ls o made of th e s e ^nen. Aj-c} dicing of the degree of a sb e stc sis present in four graces W . . . . , a J.1 - L. *.aai M A ^ A A t A 4 A I CJl w O5 la.l'i fcs 3 / / Ex'v=- - C:' " ~^ , g -1 o. oreaber 2 , 196* - c V. A B'ALONZO k .d . _ JTGZ RELATIONS DEPARTMENT 11* SC . - ~" ~ i I ta e n e lo .m e copy o f ry tr ip p o r t on t h . s t o e t o . ^ H tlng held in New York, BM tlns underlined th fe e t tht i ! " " *' .Seem i a r. no fo n ser ^ TM S . n l d :n* r i * , ere n lsh ee t ubere the ripping out moot d i f f i c u l t to c o n tr o l. s "e?hi 5 * J ^ -I d le n t fo r Of old im u le tlo n or the l n s o f t h e ^ d r y ^ ^ ^ u, . }. , -4 Cis4eIs--..3os-ceeornetnatlnwlnarit artoeocaunltheIrn*.tr`*Inwsuc'nh ,s;.ttuuaivtjjuon5 p. ersonal, ill- f it t e d , respiratory protective devloes are the ost fftc tiv e means o f p ro tectin g tne w once.s. t Du Pont Company pends ^ ^ ^ n^ t J1^1 a*rBuch"off inich stu ionf i neawsbceosntostr. ucRtlooungholny 2CO,OX ^ un d s oo ff Dp iiup*e ^innssuulai^ti.o n P uied every year and approximately /0 pe ma--. ltuCt i t i s insulation i s a sb e sto s. With rigore o f JL 5 5 St?ng Jut et d if f ic u lt to v is u a lis e a real health haxard e x is tin g ju* ia th is one uae o f a sb ea to s. Because of long tl * lag fro f l r . t exposure to arriio s i* (^tthhee mean per:ioda j1b. *. ^*.1r ^ i ' ^ e l S i . Ji?iretory d isease problem i s lia b le to ch are b ig u se rs i* p a rticu la rly true of the nylon p la n .s wh-ci asbestos inr seul alattiioonn on th e irr '"Dowthhera. ' 1 been lInnesttaallllee dd iInn. tthhee llaa es tt 2266 yy eeaarr ,s., *.*he e npoei.n.et ttuo _1 beets o f t h i s problem speak fo r themselves w i P1" . for adequate pulmonary fu n ction stu d ie s *?*ed to a d e fin ite r is k o f resp ira to ry damage. * 4 fct.hs amon& pcinonasof - 2- ii'^p^tCS ^, nSdltSuiC** Vw4US 5; asoes^os - np^-^he^onas th e lung, 5 jja~ ^r*-, IZa^ - 2 s vsr*6 feu no. --to h^^v*s of the p leu ra , r*aQ and 27 had n eo p la srs a t f K ill be noted iron t h e a t o v e _ i i ^ e s h ^ n / t h e Kt. S in a i & S S S ^ r o f 1:? e ith e r ^ Sly S T i ^ t l o S ^ ^ ' t l & ' w * the general Ipulatio.n. _ i' , _ r v ____ --r t'-e Mr. S in a i H o sp ita l , At a l a t e r s e s s .c n / : . \ llU 7 ^ '~ c b u r n e r .c e o f carcinom ata . roup fu rt.n er u n c e r l-.:e u ;:** a* 1 he noted th a t in a :or.gst th e in s u la t i o n w c r x - .s . *-*'" _v_ phis group c f > : s t e t t iv e stu d y o f 2pp .g at the ;c..-,s *e^- v c "'/s" S c a r r ie d out e v e . >e ---- v_ . . * 0d 2 0 - 'i s - r -. h - ir;p UaS--a'.-is5 we6-.. *_n..ou-.e a sed--(vobserved ip,,p , ne^xspp^evce.". - U- , were d e a th s caused -y oanoe. cb e t t e d 7 ) , and stcr.ac.t ana e tio h tr.se c u tiv e earn s frorr. Ja..t -,-<= -i*-1 r cs d id n o . 7 "1 1 . expect ed 1 0 ). ( -s*. , -ctal ef -- -A--u-g*ust - - - ^Ch. -^rrs-f1. j-J e e l i t - * ------* -- . , k ` i r s ^ v e - ' t o - . d i r l l n . , t h e ^ L r U l X o v jr wha?` ^ h s ^sm inal necF - ^ s ^ s -e aU ; c f phe g en era l p o p u la tio n ve oeer. e x p e c -e d -u- that for a v a riety of ^ i---. n ^ w.'A *'**^ '**'s f* i^u S - - . 6 LI w^* c5*^w**? isor.s th e accu ra cy c . c i a g n e s - - ^ - 57111"`0i the ^9 such d e a th s, i--i ---=--c---5s ~* s o fte n in s e c=ucrsje1, a'ni' ~e c a ra s.nc*eo u..e c . ct-----c * -' s pc .be a .y s is c f a i l o- -*e - *21-- i l l . , . - i v t-u e o f stomach can oe, ssu r/o tiv e o n ly . T nis was e. s ; ^ ;7 7 1 ^ can e - (6 o f 7 ) . T h erefo re ' our o f 13) and g e n e r a l i s e a b a ^ - - . ^ n c - . ^ i ^ ^ fflore is p o s s ib le tn a r F e r-to n e a l m^Sw*. ln addition to the "men th a n th e 5 c u . o- c-J-* - t va- we-e th re e men a liv e calasd a euoongst che re c c ra e c c e a .h s , m4 1 perltoneal -". known neoplasms (1 lunt, * 1*1-11-*-,.. C" -e c c f tongue c a n c e r. is "th elio m a) . as y e ll as 'one J P J i- J - .- j - i i S w in g s u c c e s s fu l r e s e c tic r cf ca n cer c f t.ne ceie.;> ,.. vev t- Cu e s tio n s a t .ne ^ lo calized lung cancer -ur.ir-i cf t h i s p a p e r, Dr. Hanmo.*riesrs had pres-uhatly not bssr. m= <i "."1 th a t t h e `croup of stu d ie d from t.ne group of workers l "h c lc g ic a l p o in t o. v - ev* - jf y cation cf the re su lts >h a n o th e r in d u s try sin c e u ...- - w'*__r.ll concern th a t the [(^d*reesthoasd i nnsout l abet ieonn anwyor?kaerrsr "wc"eir^er sshwo0w^ .nngr i aa-.-. a--bnormal in c id e n c e of { P lasia. 4 - 5 - A report from Turner Brothers A^ e 6 "os_Co^ " y , Bi; ^ id a Bfetoale. Tr,J?s*s m Sb sj^ ^ suitable'dust prevention 1 r i . , ensiSi e for a considerable proportion of tn ls excess. a fd P 'of a group SSeSSn S ort^ it^ I & S * U S ! t o . Hwmond had. pointed out *hat""the extreme, r a r it y o f p leu ra l j v ." ,5 ^P eculation meant the fin d in g of e v e n s very feu e .s e s ... . t"oular' study In Industry was h igh ly s ig n if ic a n t . _ ._ ..** T ^ lfa s t I r e la n d , ta c k le d th e proplem c. o?tn=eii:o/m aC';.ol<i-Bia!n0o?tni eerrppo "- t . o f vieriw.n3 ~H,`-me eh''atdhs tuBdeilefda s4t 2 oovaesr es p le u ra l m eso th eIlo n a found in - -? be4ng about th r e e - c u a r te r s l li: vp?"- the peculation a t ri5K ^. a/ -*^...--i ciorn' l ep eio^pe-e. A p * c s i t i v e , 5Sh(ilis:t ocroympoafrede x wp oitshu r ec r uwyo *9s~oe*SwwC*- / irk was o - ta .n e c in 3* *s "bod^es'w ere found in the lungs of So tched c o n tr o ls . A sbestos D0Q- e f 20* c f p a tie n ts w ith *p a tie n ts w ith mbreosnocthhuelsioamnad o2f0.5^ 0piiepuarwa; eJn^tsd c^yn_ ls of non freouenev o f fin d in g of a sb e sto s b c d .e s -*. 'fu n g 'ls^ h ig h e r (7*) ween 60 and 69 y e a rs of age went A^ % A2 r d work between ; 1915 th a n in _ tn e 50 I s ` g V S g ^ v e r 1000 to n s a y e a r of 15 and 1 9 2 5 . aetw een 1906 and . 9 0 compared w ith 600 liler com position were lm ported nto B elf was an m s u la t- ns a y e a r a t ^ h e r t^mes T his b o i l e r o p ^ asbestu8 flb *r. v p r Pneumoconiosis Research Unxt, i Dr. Wagner, of the M.R.C. ?n* . th at an a sso c ia tio n between Morgan, Wales, B ritish I s le s , no.ed that ^ r|? iy accepted. h>esrteocs enantdinpuvlems toingaartyiomnalhigandanshcoywn th at tthheerree wwaass aann ^in.^c^reas^ed kidence o f p leu ra l and peritonea exposed to asbestos dust, 5o?plle. occu p a tio n a lly _ oorpKm!nwvirwonhmwen. ^has/ b'ee^n "ex?trremeellyy . l i g a n d some o f th ese cases the J ^ M S o lo e i c a l fe a tu res o f ---------of 'an* ! I I case s* o ^ t h l s* tumor .have^een^ confirmed h is t o lo g ic a lly . 4 e r ` hese cases have been confined to one asb esto s ! * The M j o r l t y of th ese P ^ S ^ S . i & U l o n . ' h . Y . M bestos m ahufacturih| hydrocarbon, are present i H a ^ r i n ^ h i s p a rtic u la r type of asbestos. ~ ** a th a t rep o rted Another study tak in g M uriel Newhouse of th e t v E laes o f B e lf a s t was epo* ^ed ` < p r . Newhouse don School o f Hygiene -op^ca- * ng a la r g e h o s p ita l in the t r t on a s e r ie s o f ere ^ ic e d _ i_ h to t=^ ,t end of Lonac.n. V ^ n ? i * i< e n ts in whoa th e d i e n e s s c. ,Ics; the f i r s t c o n s i s t e a j f t biopsy. In . icthelioaa had been conf.rmec h i s t o r i e s were c c ta in e c . ; seven th e p a s t o c c u ? a -^ n a * a.~ o r lz in and in 6c - t 2i p a t i e n t s th e tu a o r , p e - - w - a- c 10, 7-v ..t only ten of *ne ` ru ra l. The e a r l i e s t re c o ra e - - - 42jS of the fem ales ries died before 9 P fi r T I ^ i r between the f i r s t exposure t A under th e age o . PP -n - between 16 ana pp d eveloo-er.t o f t e r a i n a l ^ i - a e . . * - a - , , ?6 pat i e c t s a t tne i"# Pci^--9" WiS -/* l^.a h e s a io a --.> ***' **. v seee*x*v*aianuncir.cc-C-2a--ar-ceteA oOj.^f <--VC*-U--t.*l w-i t*** w-*--w*7-x*~-w.-*,^__w- 5 ir.a fror: mesotne^iema na s - 'r s o se rie s ; p^.w- c= 0f th e c o n tro l groeuup-. eZVx1p--csoe--I rto0 a sb iessbto_*s___as compaerTeed-.ottocrr1J 21e.es*: w in f a c to r ie s tree main ty p e s of exposure were - e - ^ . . - .la t e r i a i s and othe: - - asoeSuOS t e x -- e s , - , --------- n d e x t ) c sure t^ a -- `o c te ts , employment^*- n -* v l t h a s b e s to s . E ighteen o* feusht home cy . c - a t - \ e s * J ^ a ^ a tiv e s were worh^nfc ^ --n :tlcved in fa c to ry werr. o. v'n ^"' - m - a s f a c to r y ope.nea - te s te s were employed in cr*e . 0* ^ c r o c id o lite . A ll th o se - wa u r t i l re c e n t y e a rs ^ .ReaV ,, r i - s tvoe of asbestos. dcse r e c o r d s cou ld be z t c . f c w ith no p o s itiv e so.-.gst th e 3o p a t ie n - s ^w^w.n^ 5 * l i V i ng a t home working tc u o a tio n a l h is t o r y ^n^ * ta d "w'*' ^h' n h a lf a. m ile o f an asbe *w Sbe's t c s , th e r e were 11 wno ^ ^ J ^ T ^ / n v e d iu th e same area tetory. Five of the control m * - If ^ two s e r i e s wcs he d if f e r e n c e in th e p ro p o rtio n o- P * - n -a tistica lly sign ifican t. ^ . . the P^euroconicsis Research Unit D~ Tar. V e e s te r, o* tn e * ,* an pao er tn a t char.nesburg, South A fric a p o ^ e - o a t ^ ^ ^ QWZh o f J nirnal experim ents have s -c c .e a e a ^ ch th e a s b e sto s wa s _ escth e 1io m a -lik e ^ - c: - * Rj i e ^ a T ' i t ' had not been p o s s i c i e ^ c c.ccula-.ed d ir e c tly *n.o ^ th e aniE a l s to ar. a s o e s tc - c -- roduce carcinom ata bi expo-a. t loud. A f u r th e r study of p le u ra l :nes^JhT U e -p o o l"E n g la n d ^ Seven- ecord s'1"was* given by V. .G1^ n_cS e e i a r i i e s of? d if f u s e m esotheliom as, eer. cases were s e le c te a a s peri t oneal . E viaenceji ixtee.n of these were A ii| ( 82Ji) of th e 17 m esotne--w...a sb e ste s exposure was o b tain ed - V /*/ es - 5- * None o<* a s im ila r number of s u b je c ts w ith can cers of o tn er / s *were ln o `wn to have h an d led a s b e s to s . Of those g iv in g an h"sto rv of asb e sto s exposure, fiv e were la g g e .s ^ p a -.o ^ l history l a t l o n e n g in e e rs and two were b o i l e r 'e-s6 ( s h ip b u ild in g ), two p a tie n ts were employed by sackware * t ure~s and had handled old sacks which had contained - t o s . Only two o f th e ^ / / ^ - ^ ^ ^ ^ t e ^ n v f r ^ e n t a l 10su reShaving0worked in th e o f f i i e s of co n crete m an u factu rers asbestos cement. Dr. We airllliiaemr Ds t.u Bd iuecshaonfant,h e E r i t i s h V iual S ^ a .- s ^ cs' rr--cc oo .- i-^ tahk a *f P S .'"l', S r S ^ U U c a WX x.- ----------- ---- - aster, wren th ese fin d in g s had been re la te d to a s e gr preportions so a ffe c te d d ie s. Op to t t e e rd o 1 9 6 ., 5 8 , ^ SS" ifS S M . i l ^ d g and t0 -als of e presence c f asoeswcsx.5 nave ucs.i w rv~ariC-t o n a lso ch c e r t i f i c a t e s were c u r re r.t.y , nc~e" -ng. :. - ` , l ,, j d t0 a th o ra c ic tumor has also in bo.n sexe, e.n.-nw eo tc*i*se***sp"o o rtlo n ately to the to ta l m atter sc^tha. 0? c? th e' males dying incidence pplasm . Even f ' r o l e ! ^ ! BuehaSan f e l t th a t lire was l i t t l e doubt* t h a t t h i s in c re a s e was a r e a - one. which tim e th e p la n t in which the men we.e employee B erlal "n el?`r a S o l cK ^ni^ulm on^y f u ^ l r ^ in v ^ s a tic n s . ^ rck syndrome, un^xorm decrease . 9~ te r< a `> oxygen s a tu r a tio n utimum b re a th in g c a p a c ity , d ecreased ^ " . a - ^ o x y |* c r e a s e d s p e c ia lly on e x e r c is e ) , normal PCO2 d exerCise occurred ffu sin g c a p a c ity . H y p e rv e n tila tio n a t " 6*e^ ? 1" lon and 1acre than h a lf the eases, an* _r _o s t s e n s i t i v e index of ve o la r v e n t i l a t i o n were i ^ c!`e a * * s a tu r a tio n . S lig h t re d u c tio n p a ire d fu n c tio n x a s a r t e r i a l oxie>* heiow~Q2 was found in h a lf l rr ee ss tt wwaass ffoouunndd iinn ss ii xx ,, aanndd rr-eid"u cJtii-oenmjpellooywm ent s e r i a l evv aa lluu aa ttiioo nn s f the workmen on e x e r c is e . p ^development or worsening 5*e made in term s o f x_ray p r i g ; * s **asurem ents? o f pulmonary func- f dyspnea on e x e rtio n and f u rth e r eom plications^of the Jtn. Follow -up 5 i s ' " vaH " h e *7 men s tu d le d te n y e a rs ago, S^men carcinoma! ^ S Y ^ u i m o n a ^ a s b e s t o s i s (c o re pulm onale). - 6- - .. o n . Nine of the o r ig in a l workmen are i a l i v e ? 0one"fo llo w in g th e r e s e c tio n of a lung or lung c^nce. . we~e p re s e n t.e d. vd,,y wo*jeers --- t ^ " i t a i4.n. d iscu ss:4-`*--6 v K e P| ? r l u t l n e !u n g fu n c tio n ? t u d i . s . Xn ^ e _ f l r s t , U Hunt, o f B r i t i s h B e ltin g ^ " ^ ^ " ."g ^ ^ n U o 's t u d l e s on 813 lao, g*v* , v t | r j " n- 5C ss< n'g fa c to ry , R outine work in t h .s ' cvees in <=.n asoes--/S - - ac e- - - -|0nr' <- an a so e sto s S4* o f lung f u n c tio n W. s t e r t e o . n ^ 1 ^ 1 9 0 . c?M t, , jctile plano n t^e -<^*r;t v alu es, gas tra n s fe r t c- norr.al fig-uires V* wr^>7;g's~ V e n tila c i n on ex ercise.. ,:tor c o e ffic ie n ts , "yip?* ve s*'v <eots used in th ese te so s ii forced dreat.oirg cao-c- -- ;y.., s -. soaoure groups Ire v o lu n te e rs of boon sex es T1, 5Se . tc- departm ents oW ; v 5 y"nd the reg ressio n formulae isults were oner, analysed e-waw-Sw-Ca-.^^ , w :r>:ing in thcse_ ioained a p p lie d to tn e r e s - i - s ;*:v ^ . - c- lon te s o s were a .so icuraoicr.s exposed to a s e e s - - - . ~-.er.t from 0a k in 5 eow:ar's,: air. scierepeanrts-e-.n-t.se vver...e- r e ^ s - e . - - -^ de,,: e---^ iV_a_s pt ere_.v_ai_er.os-._v; Seo;m- e .f f i c u l t i e s were er.co---- wl~e overcome a rc ' *-'~J c l 1 `H " -1--I--=-~--c---< - .* :- o r a_i _n _v i r h m0u.h-e s vo e` cdnanr Ci ceu sPCyi.-n- -tS * - -" '" 1&" 1S-. *15-1-1--^-1 _...= - Ire iS l ? ; S a r l " n s f e r 'a n d j i t a l 'c i o a = i t y before any r a d io lo g .c - clin ical signs are evident. j ***> v v v t T^o^sor. ans *. 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The e th e r paper g-ve.. -1 K eiicin e r.d from Cape ^ r-` ---- ^ c*-` TlvII-V"?-- --s Ltd., Lon ton, r.gia.i-, ---- -& -c- S-_5.-_or. a...- ---------- 7 * caoacitv vere tne ces- _ V--.t ;-_-u.--: i ; : ; r 3 S H l U S i i, r- . .lc^s ;. tthhei -iaSniyy ppuullra.oonnaa_ryy -f--u n c tio n iesC5 ::d I t ould appear . r o , . v , ccoonncceednesus a t tehngi sa.-me ieeitningwo*rhk aw- itt-hJe isv: of p erso n s n o . n c ... u ll^ n o .B ... fc e ln . ln the asbescos s c e ste s . and c e r ta .m y n - - w.*o-&..- - *--c"s,''t This f a c t s.no-i- r*ius*rv, - s 5-^ a ^ e r wh--i ^ - s ^ c ^ sc r.'s occups.t.or. .-- come in mind and em craces no- *1- i 4. `J l - ". s e lf worker a t home *-sc h is h o o dies - f o r Lr.szs.r.ce, a - - - Ur i n home in s u la tio n . ^ a t hav. a m aterial .xporur. ff.eI c-.heiior.a i s extrem e. ince the prognosis -o r a a.as.. - _e l_ j_. im p o rtan t ten, varying from 'a few ! ?e exocsed to asb esto s vnether as ensor.s w ith in th e company s .n .u ^ o . ^ ^ ,, eiJ m a te ria ls as asbestos fib e r penetrates through the resp irato ry passages O tte r s and not the c la s s ific a tio n of the te n 's occupation. 1 For p e rso n s who would l i k e tore in fo rm a tio n on t h i s to p ic , a b stra c ts of the Conference I.sa iDl ss i raa rcrwa vua- i i a b l e from th e on th e w .rui t er aBanniddo liiottg iiicssa l eexExppf ef ecctetdas tohf a t the f e e d i n g s o f th e conference w ill be p ublished *in th e y e a r. 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