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Table 1. Delayed hypersensitivity skin test results with Multi-Test in subjects exposed to TCDD.
Low Risk
1 High Risk
I
Male Female Children*- | Male Female Children
Total Subjects
No. Anergic
Geom. Mean Score, mm. r
Mean No. Antigens Posi tive^
12 10
01 (10.0i)
17.1 8.2
3.9123 2.9 2 . 0 1.9
8 0
10.6
3.5 1.8
1 27
22
1
l 1o
1
1 (4.6S)
l
1 I 12.6
9; 1
1 l
l I 3.3 2.8
I 1.5 1.7 .
15 0
8.7
2.7 1.3
1. Children < 17 years old. 2. Induration > 2 mm at 48 hours is considered a positive reaction. 3. Data expressed in the mean number of antigens positive 1 S.D.
Table 3. Lymphocyte proliferative responses in subjects exposed to TCDD.
1 1 Exposure
l
! 3H_thymidine incorporation, cpm
1
I 1
PHA
Con A
PWM
Tetanus
l 1 High
1
-
1 Low
Adult Children Group
Adul t Chi 1dren
1 63,8341 | 4.81 t -1812 | 293 Il | 83,878 1 4.92 .18 I1 8
I 67,717 I 4.83 .18 l 37 1 1 ! 58,261 I 4.77 .19 I 15
1 [ 81,340 1 4.91 .14
15
48,124 4.68 t .20
28
68,188 4.83 .20
8
51,999 4.72 ; .20
36
44,370 4.65 t .17
13
58,482 4.77 .19
5
37,540 4.57 .21
29
41,053 4.61 .17
8
38,278 , 4.58 .20-
37
34,014 4.53 .25
14 .
52,643 4.72 .12
5
,12,979 4.11 t .69 29
7,256 3.86 1.04
8
11,446 4.06 .77
37
7,077 3.85 .71
15
42,485 4.63 .20
5
Group
1 63,330 1 4.80 .19 I 20
I
47,908
4.68 t .18 18
38,157
4.58 .23 19
11,084
4.04 .70 20
1- Mean cpm of optimum response. 2. Log geometric mean cpm 1 S.D. 3 . No. in each group.