Document qagdO0Ke4MGegQea9Y0XrLQ7x

FILE NAME Household Contact HC DATE 1954 DOC HC035 DOCUMENT DESCRIPTION Abstract from Medical Journal - Pneumoconiosis Abstracts PNEUMOCONIOSIS ABSTRACTS VOLUME II Reprinted from the Bulletin of Hygiene for the years 1989 to 1950 inclusiva by permission of The Honorary Managing Committee of tho Bureau of Hygiene and Tropical Disonses PITMAN PUBLISHING CORPORATION NEW YORK TORONTO LONDON 1954 pp 167 -168 ASBESTOSIg 107 The authors repall the reaction which takes place in tho lungs to dust partiolos of asbestos but no ansa of asbestosis was found among the men Some men have worked with amosite for so long as seven years without developing corna but the majority devoloped corns within the first three or four month~ Removal of spioutes with forceps after work is useful in prevention Cure can be obtained by simple paring of observation of workers in the ashostos industry with special reference to the study of the significance of the nabosbosis body Thoy olnasity their conclusions undor four headings Asbestosis bodies are diMoult to find in the early months of exposure owing to the fact that the workers have no sputum unless an attack of influenza or bronchitis produces expectora- Mon. In one worker nabestosis bodies were indood the cornified areas until all excese keratin is removed Since a corn is relatively innocuous and leaves no serious in it sequelae thore is often little intorest takon B. E. Colla found after twenty days exposure but this is unusual and four to five months is the average time Four illustrativo examples are ofted 2 In 102 workers observed over a period of four yenis who had nolthar radiological signa nor olinical symptoms of the disenso asbestosis bodies were ultimately found in all cases At flust the bodios were short tihlok and frag- Nono L. On the Histology of Asbestosis Aolo Path mented but later longer specimens were found with PS at Microb Soandinavica 1040 v 28 No. , typload olubbed extremities The numbers of bodios 68-0 8 fign Increased with the exposure they occurred singly in the sputum and were accompanied by sabeatos SA This artiolo glvos a short account of tho histology of fibros 8 The fluding of clumps of asbestosis bodies nabostoale as seen in two workers in Finland who bad first recorded by Stowany TATTIRBALL & HADDow boon exposed to the amphibole nabestos of that this Bullolin 1088 v 8 27 is confirmed Two country This variety of asbestos is harder and more onses are recorded at considerable longth in which elaatio than others and therefore is considerad to be there were definite radiological signs of the disonse especially dangerous The reviewer's general impres- and in which the sputum showed there olump~ 1 slon from experimental work is that the more brittle Lastly the fact of the persistence of asbestosle bodies this asbestos ^ brothe more likely it is to break up into in the sputum after the exposure has ceased is stressed very short lengths and to penatrate lung tisane but the authors are convinced that the finding of The chomionl analysis of this Finnish variety is given these bodles is only one of the diagnostic features of as follows siliolo nold 1056-27 aluminium oxide asbestosis and that it cannot be accepted alone for Al 2.50 ferrous oxide 80 4.18 calcium oxide purposes of diagnosis from a medico point of view OO 0.25 magnesium oxide MgO 81.44 per cent - 8. Roodhouse Gloyne The asbestos needle partioles of this variety were found to be noticeably amaller than those des- oribed by some other workers Brief accounts of BOARD OF TRADE Gorman Industry F.I.A.T. Bs the cellular and connective tissue romotion to the . Abre the asbestosis giant call and the asbestosis body Final Report No. 1070. Technical and Scientific are givon With regard to the last named the author Developmienta related to the Asbestos Industry in Germany 12 mimeographed pp 7 figa 1947 accepts both the mechanical and chemical theories of Mar. 28. London H.M. Stationary Office . causation but is inclined to think that the moohanical factors the most important although the shomical factors may have some significance in a later phase S. Roodhouse Gloyno This report is a description of the machinery and Installation of the German asbestos industry which is conaldered to be of interest to American industry and . is a supplement of previous reports especially Fiat Final Report 400 and Blo Final Report 404 Item 23 The main problem for the German asbestos industry Skavlem J. H. & RITIERHOFF R. J. Coexistent Pulmonary Asbestosis and Barcoidosis Amer J. Path 1048 May v 22 No. 8 498 81171 ^ gs on 6 pla 20 vefa ja regarded at present as one of lack of material in which the British Zone is not so badly off as the American The report consists broadly of thran sections one dealing with Industrial plant another with problems of dust control and a third with some LUTON P. HAMPHIX J. & FAURD P. La signification de la pr^'senosde oarps asbestosiques dans l'expeoboration des travailleurs de Pamianto The Significanos of the Presence of the Asbestosis Bodyin the Expectoration of Workers Asbestoa Arch Malad ProfessionnelPlaorlsa 1947 v 8 No. 1 50-68 7 Nga 88 r^fa experiments made by German soiontists during the war to prepare a synthetio asbestos The present position with regard to the plant and installation is molely an engineering problem The preparation of n synthetic product has beon hold up by the collapse of Gorman Industry and not a great deal appears to be known about it but the basla idea soams to have boon gelling of sodium silloats with hydrochlorio acid washing out of tho gol to remove Nall by After a detalled historioal introduction to the subject the authors glvo their experience of four . yours liquefying Ib sol to 14 por evaporating under steam pressure evaporating th" cont SLO with the addition 6-10 por 1.314 a mad Ae 108 PNEUMOCONIOSIS ABSTRACTA introducing a spinning proogas and cent sugar the fibre washing the sugar residue and fdirnyalilnygageTihneg section on dust control has a direct boaring on general industrial hygiene For many years before the war insurance Borue- genossenschaft against the risks of dust and accidents was compulsory The use of respilatora WAB FBODIN- mended only to extrome coasa reliance being chiefly an efficient dust control organization The placed on translation of the Regulation for Dust report gives a Plants issued by Provention in Asbestos Processing the German Government in 1940. This lays down general engineering precautions for dust control with detalled instructions as to the protection of machines and the provision of oxhaust equipment Many of these are already in use in Bultain but the detalls are too technical for abstineblon An offlolal centre for advising on dust prevention especially in the onse of the installation of new plant was provided by the Government Children under the age of 18 were not considered sultable for dusty occupations at no details are given however na to the regulations for their exotuafon It was forbidden to eat or to remaln in endangered rooms during rest parlods Outdoor clothes were not to be kept in workrooms and work clothes had to be cleaned regular lutervals to cultivate tho tuborolo bacillus on 510 gol contain- ing various nutrient substances but without success The weltor the report states that further informa- tion on the two substances mentioned ann bo obtained from the Wilhelm Institut fur Hillkat Fo18- chung in Dahlem The substance formed in normal blood had 1.8 per cont A10 6 por cont N but no Iron or cholesterol It was soluble strongly alkalino with melting point over 260" presumably Contigrade and had been isolated from the lecithin fraction in the blood The second was a insoluble substanco from the lung tiasua and could be concentrated in the ester fractions The leolthin compound on the other hand wna almost completely absent from lung tissue In silloosis the melting point of the extracted mixture of enter fab was found to increase in relation to the moverity of the disenso Baily onses of silicosis yielded a mixburo melting at 45 whilst the material extracted from more advanced onace melted at 72 81Bxtrao- tion of allicotie lungs gave a higher proportion of lipoids ostors free fatty nolds and phosphatides than was obtained from healthy lung tlsonG 8 Roodhouse Gloyne time not stated The writer of the report also interviewed Dr. Luisa HOLZAPPIEL Who had had charge of an organization la Berlin for the investigation of allloosis problems before the collapse of Germany Sho stated that she and hor staff had been engaged for some time on the leolution of organic silicon compounds Two impor- bent onos had been discovered but their chemical has not been completely dotermined ownhmepnostihteiw onar ended One was a silleon compound of the lipoid group obtained from the lungs of patients suffering from silicosis accompanied by tuberculosis the other was a Si compound present in normal blood The isolation of these compounds had been twotthaht at extarndemely ttedhieous takingtf ook or verom threetection oyeafrs extremely Russianstho of Borlin they had ordered tho destriction all tutorial on the ground of risk of Infection Dr. Holzapfal considered that there was no rlak of tuberculosis provided that sllloa metabolism in the body was normal and she regarded disturbed fat metabollem in undernourished workers as a predisposing cause of tuberculosis She was of the opinion that the compound isolated from healthy blood might have some therapeutio value both in tuberculosis and tuberculoallicotio patients . The striking resemblance betwaon the bissue of a sfllootio lung and vulcanized rubber suggested to her the presence of ohain organis silloon oxygen compounds probably formed when the fresh surface of quartz grains venoted with some unknown constituent of the blood The presence of oxygen was necessary she believed for that reaction to take place and she further expressed the view that a compound in which the silicon atoms are sumpletely surrounded by organic radicals probably cannot cause silicosia because such a compound beinsoluble and unreastivo Dr. Holzapfol had tried Wisudrjua O. Ohanges in the Lungs in 128 Oasen of Asbestosis observed in Finland Acla Radiologica 1947 Apr. 30 v 28 No. 2 130 5210 Age 10 refs This article lo a record of 120 radiologically manifost cases of asbestosis among 478 workers in Finland employed by the Tinaka Mineral A.B. Firm Of the workers affooted thirty were employed in the Company's dressing works at the mine in N.Enstern Savolax whille ninety were working la the factory for Anished products near Helsinki There were ninety 75 per cent Instances of mild asbestosis of stages I and II with an average medium.plexes fund.1-11 gxposuro 34yours twenty moan average of 70 meen exposure of fund.1-111 70 years and nine 7 por cont of advanced stage III with an average mean exposure of 11 yonus During the observation time of two years twenty seven of the thirty patients in the primary stage progressed to stage I of the stage I casos four of thirty patiente progressed to the intermediato stage II and tho onme number passed to stage II of the stago Il cases two out of ton advanood to intermediato stage III Two deaths occurred before the commencement of the examination sinos then no rollable information has boon forbhooming with regard to others although it is probable that some deaths have occurred The method of radio- logical classification used wae that of Saupu viz primary stage Stage 1 extremely fine network in the middle of basal folds II denser picture with numorous extremely small nodular shadows III marked shadow of middlo und basnl folds with confused contour of heart shadow mer e n oe et ee ome te quen e BERR a se tes. .