Document qa21E2R4wnxDk5NxJ7Rd5XgrG
AR226-3125
HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE
H-24119: STATIC, ACUTE 96-HOUR SCREENING TEST TO FATHEAD MINNOWS, Pirn ephales promelas
PURPOSE: This is a rangefmdmg study designed to provide an estimate of aquatic toxicity using fixed test concentrations and data measurements at predetermined intervals.
GENERAL INFORMATION WORK REQUEST NUMBER
HASKELL NUMBER! SERVICE CODEl
MATERIAL TESTED: SYNONYMS/CODES;
SPONSOR:
NOTEBOOK ID; SUBMITTER'S NOTEBOOK NUMBER^
COMPOSITION CONTAMINANTS'
CAS REGISTRY;
MSDS: Not supplied by sponsor
TEST CONDITIONS
Nominal concentrations tested: 0, 0.5, 1.0, 50, 500, and 5000 mg/L.
Nominal Concentration
(mg/L)
0
0.5 1.0 50 500 5000
Test Initiation (O hours)
Dissolved
Oxygen
(mg/L)
PH
8.9
7.0
8.9
7.0
8.9
7.0
8.9
7.0
8.9
7.0
9.0
7.3
Test Completion (96 hours)
Dissolved
Oxygen
(mg/L)
PH
2.7
6.9
7.9
7.1
7.1
7.1
6.6
7.1
6.8
7.2
1.1
6.9
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H-24119: STATIC, ACUTE 96-HOUR SCREENING TEST TO FATHEAD MINNOWS, Pimephales promelas, CONTINUED
RESULTS
Based on visual observations, the water control solution and the 0.5 and 1.0 mg/L test solutions were clear and had no color throughout the test. The 50 mg/L test solution was clear with a suspended substance, the 500 mg/L test solution was slightly cloudy with a suspended substance, and the 5000 mg/L test solution was cloudy and white in color with a suspended substance throughout the test. In addition, the 500 mg/L test solution developed a white cloudy film on the bottom of the test vessel after 24 hours that was present throughout the remainder of the study. Mortalities were 0, 0, 0, 0, 0, and 80% in the 0, 0.5, 1.0, 50, 500, and 5000 mg/L test solutions, respectively. The 96-hour LC5o, based on nominal concentrations and mortality, was between 500 and 5000 mg/L. All water quality parameters were within acceptable limits with the exception of the D.O. in the water control and the 5000 mg/L test solution. The D.O. of the water control solution and the 5000 mg/L test solution were below what is normally acceptable throughout the final 24 hours of the test, but it did not affect the validity of the study.
CONCLUSIONS
H-24119 exhibited low toxicity in a 96-hour, unaerated, static acute test using Fathead minnows, Pimephales promelas.
WORK/AUTHORED BY:
^A^f^W^MM<L Laurie D. Bouchelle
Toxicology Associate
APPROVED BY:
Pa'UlW.Grube.B.A. Study Director
i^-^oe-lW
Day-Month-Year
l^Su.yc
Day-Month-Year
DISTRIBUTION:
Company Sanitized. Does not contain TSCA CB1