Document ppReMNak229LML7zEzKzXzRv6

1 _J______________________________________________________________ _129. . 1* ' | enumerated are related, just as he thinks they are in ear!l coidosis to a. protean binding, that is protean will bind j! calcium in certain diseases,- but as far as I'm concerned, j | that's a description, not an explanation. I don't know. ! i. 1 UNIDENTIFIED SPEAKER: i i ---------------: i j What is the dosage of your ACTO for that treatment? '' BY DOCTOR HARDY: Well, it varys 'a great deal. In general, we j! have given him 200 milligrams a day, ACTH embodied into i i fifty milligrams every six hours, for a few days; then down. j! to a hundred milligrams spread out; then shift to the oral . | cortisone, keep him there one or two weeks until you're sure j that you have what would be the best possible benefit iron .j. the symptomatic standpoint, and in various cases, we have I tested this by pulmonary function study and cardiac cather- ; ization study and then we do what Doctor George Dorn calls . ! titrate the dose, meaning let him go down to the point be ll !; .low which-he is still ccsnf ortable and then keep him there. i; ' I'm a great deal older than I was when I talked i! j about this in 1950 and I have patients that have been on I ?5 milligrams of cortisone, 25 milligrams every eight hours. for a year, and I can't see where I've done any harm, and i| ,[ I've taken symptomatic patients from a complete chair pa tient back to forty hours a day - four hours a day, and * #i this is very impressive even though in all honesty, I don't SEVENTH SARANAC -0153