Document pmrnKBErdQkVaNQ5Q2Vgo2vpw

For Distribution, See Page 2 E. 1. d u Po n t d e Ne mo u r s a n d Co mp a n y Haskell Laboratory for Toxicology and Industrial Medicine P.O. Box 50, Elkton Road Newark, Delaware 19714 May 24, 1991 DU PONT CENTRAL RESEARCH AND DEVELOPMENT CONFIDENTIAL To: K. D. Dastur Chemicals B-17249-5 From: C. F. Reinhardt, M.D. CR&D Hashell Laboratory ^ R. N. Ligo, M.D. Human Resources N-11400 tfl/Ls' : / LEAD AND LEAD COMPOUNDS ADDENDUM TO HAZARD DETERMINATION LETTER DATED JULY 10, 1989 Lead and lead compounds were reviewed July 10, 1989 according to the corporate guidelines for control of carcinogenic, reproductive, and developmental risks posed by chemicals made or used within Du Pont- That review concluded that lead and its compounds should be handled as reproductive and developmental hazards which represented a continuation of the practice already in place. However, the recommendation was made for women of childbearing capability to avoid exposures to lead above background as measured by blood lead. In the United States, blood lead levels average about 10 ug/dL. The recent Supreme Court decision in the Johnson controls case prohibits all fetal protection policies that preclude women from obtaining certain jobs. Therefore, as a guide to protect the fetus, women of child bearing capability who might elect to work with lead or its compounds should be advised to avoid adding lead to their normal body burden as measured by blood lead levels. In other words, when background levels, as reflected by blood lead measurements for that geographic area, are significantly exceeded, the women should be advised to consider other assignments that would not expose them to lead. DUP040011327 Copies to; W. P. Anderson B. A. Beach N. Bell A. S. Berg M, W, Brockman M. M. Coburn j. E. Cole J, r . cooper K. D. Dastur M, S. Deak J, R. Baden G. E. Harper T. Hendrick III G. J. Hollod D. W. Johnson B. W. Karrh, M.D. j. s. Kelley J. E. Leemann C. J. Markovchik j. f . Matheson W. J. Mottel G. J. Patterson V. R. Rice G. P. Robson R. A. Romanel1i S, C. Saltzman B- K. Saydlowski A. H. Schultz C. S. Seringer J. M, Wesley polymers Consol Chemicals HR Fibers AP CR&D HR Chemicals Polymers AG ML&S AP Chemicals Conoco HR EA chemicals ML&S Conoco HR AP LEGL DuP/Canada Chemicals ML&S E/ IMG Chemicals Chemicals ENGG E. VL. De Whitt, Jr. S. W. Dixon W C. Haaf M. J. Hofmann A. MacLachlan F. P. Mulherln T. J. Nelson J. C, Olguin p, c. olguin R. D. Richardson M. E. Sabla L. C. Schaller HR HR HR CR&D ADMN HR HR HR HR HR HR HR J. G. Aftosmis J, R. Gibson A. M. Kaplan N. D, Krivanek H. J. Trochimowicz CR&D CR&D CR&D CR&D CR&D D-12026-2 Pittsburgh B-12252A N-11458 CRP MR-2015 B--3.324-5 E-326/301 N-11539 B-17249-5 0-12016 WM 6-252 CRP-700 B--1218 CRP HR-2092 Houston D-2042 M-7722A B--16271 CRP-700 Houston N-11543 B-5222 D-7016-2 Kingston, Ontario, BOD 918-8 D-2086-2 BMP 21-1152 B-14236 B-13256 L-2316 Canada s N-11498-3 N-11502 N-11530 E-326/208 D-9152 N-11500 N-11503-2 N-11498-1 CRP-718-4 N-11502-2 BMP 14-2170 N-11466 Haskell Laboratory Haskell Laboratory Haskell Laboratory Haskell Laboratory Haskell Laboratory 2- - DUP040011328 Copies (Cont'd) International Koichi Fujiwara M. Fornasari G. Grulich G. Heins E. W. Leppin G. Minionis L. Murphy E. Salazar I. A. P. Scott J. C, Siqueira J. M. Taylor D. Wika DuP/Japan Tokyo, Japan DuP/Argentina Buenos Aires, Argentina DuP/Taiwan Taipei, Taiwan DuP/Columbia Bogota, Columbia DuP/Germany Bad Homburg, Germany DuP/Venezuela Caracas, Venezuela DuP/Australia North Sydney, Australia DuP/Mexico Damian, Mexico City DISA Geneva, Switzerland DuP/Brazil Sao Paulo, Brazil DuP/Canada Kingston, Ontario DuP/Far East Singapore CFR:RNL:rcg May 24, 1991 HAZ6.11 -3 DUP040011329