Document pmdYMaq2K1nq80DNOOw15B2vj

Unit Code 8308 1/14/89 2:54PM UROBILINOGEN, 48-HOUR, FECES -- Seneral Information FEE: $122.70 LABORATORY AREA: Porphyrin32/HC25 ADNAYA(LSY)TTIECSTTIMSEE:T 1UPd:ayMonday through Saturday TIME OF DAY: Continuously LABORATORY HOURS: MAXIMUM LAB TIME: 3 days COMMENTS AND OTHER REJECTION: CV 6%. If thawed but cold, note to laboratory. If RANDOM SAMPLE is rec'd, REJECT.If client nsistsontesting: 1. Consuitation with Dr. McConnell must occur beforelabwill accept specimen and perform the assay. 2. We have NO NORMALS for a RANDOM specimen. 3.Iftestis run, the report will be as gramsof specimen. Should be a 24, 48 or 72 hour collection. Lab will NOT do on anything ther than the above listed timed collections. Please do not call the routine laboratory for approval of specimen not meeting collection duration criteria. SPECIMEN RETENTION TIME: Until reported LAB CONSULTANT TO CONTACT 1st: Dr. McConnell 47437 LAB CONSULTANT TO CONTACT 2nd: LAB CONSULTANT TO CONTACT 3rd: CLINICAL CONSULTANT: CLINICAL SERVICE: TECH TO CONTACT fst: Paul Chezick 4-8081 TECH TO CONTACT 2nd: Chuck Kroll 4-3232 LABORATORY: Porphyrin 4-3232 ARE-O148 : . 03589 2 SEH KOLO OA UDPiED 66. VT Nor "Unit Code 8308 1/14/99 2:56PM oe UROBILINOGEN, 48-HOUR, FECES "dethod and Reference METHODOLOGY: Colorimetric METHOD: Urobilin in the feces is reduced ta urobilinogen by treatment with alkaline ferrous hydroxide. The urobilinogen is then allowed to react with Ehriich's reagenttoforma red color which can be measured `spectrophotometrically. 03590 ed SET WOIO3L OAM WPIED 65, PT NUT Unit Code 8308 1/14/99 2:56PM - oo. UROBILINOGEN, 48-HOUR, FECES tinical Information CLINICAL INFORMATION: - Urobilinogen consistsofthe colorless end productsofbilirubin metabolism which are oxidized by intestinal microorganisms to brown pigments (stercabilin). - Normally, fecal urobilinogen approximates the total excretion of bile pigments (the breakdown productsof heme). USEFUL FOR - Diagnosisofdisorders involving hemolysis and hepatic obstructive conditions INTERPRETATION - Increased destructionofred blood cells, such as in hemolytic anemia, increases the amount of urobilinogen excreted. - Liver diseases in general lessen the flow of bilirubin to the intestine and thus decrease fecal excretionof uroblinogen. - Complete obstruction of the bile duct reduces the urobliinogen of the feces to verylow levels. Clay-colored feces in obstructive Jaundice resus from the exclusion of bile pigments from the intestine. -Oral administration of broad-spectrum antlbiotics diminishes conversion of the bilirubin to urobilinogen in the Intestines. CAUTIONS - Information about oral broad spectrum antibiotics taken recently by the patient must be accurate. Oral broad spectrum antibiotics decrease urabiinogen measurements by diminishing bacterial conversion of bilirubin to urobilinogen in the feces, leading to faisely low values. IMMEDIATE fixationofspecimen by the prescribed preservative (sodium carbonate/petroleum ether) in an opaque container is essential, since urobilinogen is light sensitive. Poor fixation gives a falsely low reading. REFERENCE ~ Schwartz S, Sborov V, Watson CJ: Studies of urobilinogen: quantitative determination of urobilinogen by meansofthe Evelyn photoelectric colorimeter. 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[rT -------- ists RE eileen dun, Fes 03602 --_-- r= o = IVIATU = -- EES er wom rL T eEL i sgft ,L e os=o (TS) ed ew 0.07 UB/GH Spec. en Norwals not applicable. ne C03603 E2--=EI EI T m Ernea o e L Lr lle MEDICIAVL LIABAOTRAUTORIES Re--ta--vee acs ---- TW 0.16 UB/BH Spec. Norsals not applicalbe. 03604 IVIATO --o=n ee E L mee eLg ]IeTe MEDICAL LABORATORIES oo fsbo wma (5) aFE me, Toxicology Services reo rn roo 2en J = C03605 Gores i aDioInVDIbAoRYTUorEs pr - mfomrme een we me CFE Mwuimi I EE vom r e [| oem sn, om Fiecryhieesd bm Bldg. 220-2602M, Center esting tor, Fe io newin ow 0.08 UB/GH Spec. Norwals not applicable. , 105534 Urobilinogen, 48-Hour, Feces 03606 p-- MEDICIALA(ABTORLRTORIES oe il =-rt wom Ee-- i r-- eo Shirwan pn CE J dl VY = fe ee LM I mr uh wom iow [ER -- J wpye om 0.04 UB/6N Spec. 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