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ARQ26 _ 120
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
WASHINGTON, D.C. 20460
or 23 22
PREVETNoTnIeONssFetscanocEESs MO
MEMORANDUM
8
SUBJECT:
FROM:
TO:
Draft PFOA Exposure Data Gaps Discussion Document
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CMhaermyicF.aDloCmointnriolk Diision
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Administrative Record File AR-226: PFOS, PFAS, PFOA, Telomers, and Re~ed
Chemicals
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draft prior
document to the call,
was
shared
with
Lynne
Harris
of
FMG
and
with
Steve
Korzeniowski
of
TRP
Record
Please include file AR-226.
this
transmittal
memo
and
draft
document
in
the
public
Administrative
CONTAIN NO CR! I
Recycle Pindwin V PE aOFGg odnia k on-- cl yto -- Ps i 8%Pocr o cote
Draft Exposure Data Gaps Document, 8/30/2002 For Discussion Purposes Only BACKGROUND
PHFumOaAnisblsuofofdicmioennittforroimngEdPaAt'a,ScpoeurpslpeecdtwiviethtowhgeanteirsatceurcroenntcleyrnunadbeorusttopootdenatbioaultPtFheOhAazraisrkdss. of iUsnadekresytatnodeivnaglutahteipngatwhhweatyhser(atira,rgweatteedr,acdtiieot,nsethca.)veanpdotseontuiraclestothsautccleesasdfutollPyFaOddAreisnshtuhmesaen blood cleovneclse,mas.logIfiqcuaelsnteixotnssterpe,mgaiivnernetghaerdpienrgvapsaitvhewneasyssofanedxpsoosuurcreessoafcProFsOsAthecognetnreirbaultipnogputloabtlioono,d isa tdheattaimlaedyldiefegcryacdlee taossPeFsOsmAe,nttohaft cloeamdmsertociaamlataectriivailtsieascacsosuonctiiantge-dtywpiethanPaFlyOsAi,s masaywelble anseccehsesmaircya.ls aAndseutnodferexsptoasnudrteh-eresliattueadtiionnfwoirtmhatPiFonOgAapasretohauttlwionuedldbehleolwp.toTrheefsieneionufrorambailtiitoyntgoafpusrtahreer evaluate exemplary and not necessarily complete.
INTERPRETATION/ANALYSIS OF PFOA BLOOD DATA
What are the pathways (air/water/dictletc) and sourcesof PFOA leading to blood levels? tChaenresppeercfilautoiroinonaftebdloproedcmuorsnoirtsortihnatg udpatoanhbeiloptiicdoenrtaibfiyotPiFcOtAranpsaftohrwmaaytisoansndgesnoeurractees?PFArOeA? cBhlioloddredna'staeinnvdiircoantemsentthastaerveemnovsetrylikyeoluynrgescihdielntdiraeln, haasvceoPmpFaOrAedletvoeltsh.e Saidndciteiyonoaulng PenFvOirAoncmoentnrtisbu(tseuc1h0 cahsiolcdcruepna'stieoxnpaolssuertetsi?ngs)ofolder individuals, what are sources of
rHeicgehnetrelxepvoeslusroef.seWrhuamt PPFFOOAA ienxpnoosnu-rweosrkweorulpdopeuxlpaltaiionnsthmearyamiinfdiiccaattieonasnoofntghoeisnegdoarta?
Given what levels?
is
currently
known,
what
are
the
most
logical
strategies
to
reduce
PFOA
blood
General screenof other perfluorinated compounds in human blood?
Metabolismof POS and other chemicals to PFOA?
8
CONTAIN NO Cc
5= 2 3
2
Draft Exposure Data Gaps Document, 8/30/2002 For Discussion Purposes Only
SELECTED OF PFOA
INFORMATION
NEEDS
FOR
A
COMPLETE
LIFECYCLE
ASSESSMENT
Physical/chemical Properties and Fate and Transport iAdetnhtiofryouagnhduenvdaelrusattaenedxipnogsoufrePFpaOtAhw'ayps-.chReemlepvraonpterdtaiteas piesrctraitiincianlgitnootrhdeer to Speormsiestaernecaesoafndinttrearnessptoritncplrudoep.ertiesof PFOA would contribute to the latter goal
aditrmeocstpphheortioclyosxiisdaitnisoonlution, gas phase and soils aredascotripotnio(nr/eddeuscotripotni-oonxidation) in soil/sediment; volatility from soil and water
PFOA Manufacturing, Processing and Industrial Use
PDeFsOcrAipptrioocneosfsemda/nuusfeadctoutrhienrgt,haanndasparopcoelsysmienrgitzeacthinoonloagiidees? as well as uses? Is Sites/releases/sources (past, current and future)? `Waste streams? Disposal practices?
Exposure analysis dispersion calcs or
(time, duration and monitoring data)?
extent
of
exposures
usually
estimated
with
Exposed populations?
PFOAConsumerUse
Description of uses and products?
releases/sources?
`exposure analysis (time, duration and dispersion calcs or monitoring data)?
extent
of
exposures
usually
estimated
with
exposed populations?
ES
Draft Exposure Data Gaps Document, 8/30/2002 PFOA Treatment/Disposal Issues
For Discussion Purposes Only
c`WohmaptohuanpdpsenesffteoctPivFeOlyAdaenstdriotysepdrdoudruicntgs dwihsepnostahleaynadrebydiwshpaotsemdeocfh?anAirsemt?hese
tAhreey tahree bdriesapoksdeodwnoorfdepsrtordouycetds vwihaiicnhcicnoenrtaatiinonPoFrOoAtheorr prreolcateesdsecshesmiignciafliscawnht en
sourcesof chemicals
exposure? A detailed could be informative.
thermo-chemical
analysis
of
PFOA
and
related
Are there resulting
measured levels of PFOA in the from adsorption onto particulate
atmosphere, matter?
from
stack
emissions,
or
How does Virginia?
PFOA
get
into
subsurface
water
(wells)
outside
Parkersburg,
West
How effective processes used
is removal in potable
of PFOA from water plants?
drinking
water
with
purification
rDeolepasoewethregPenFeOraAtiionnthfeaicirlisttieesamthvaetnutsseotrhferoTmentnheessceoeolRiinvgertowwaetresr? inadvertently
GENERATION YMERS
OF
PFOA
FROM
OTHER
CHEMICALS
SUCH
AS
TELOMERS
AND
Manufacturer/Processing/Use/Disposal ibute to PFOA Blood Levels
of
Chemicals
That
May
Degrade
and
`Amraenutfhaecretusriignngi/fpircoanctesssoiunrgcaesnodfusPeFlOifAecoyultes?ide its normal
Are there PFOA?
chemicals
that
biodegrade
or
photolyze
in
the
environment
to
produce
What are PFOA?
the
conditions
under
which
related
chemicals
can
be
transformed
to
How are PFOA precursors transported or distributed in the environment? Are telomers a significant PFOA source?
t`hWeatpeprbsulrevreolu.ndWinhgypoils ythTiFs?E facilities is reported to be contaminated with PFOA at
&
H