Document pmBG3xNGJ6X1Qdpm0NbBg2296
FILE NAME Talc TALC
DATE 1974
DOC TALC501
DOCUMENT DESCRIPTION NIOSH Memo RE Proposed Regulation on Asbestos Particles in Food and Drugs
,
.
.
XXXXXXXXXXXXXXXXXXXXXXXX WIC ULNIE RI AU
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXX
i
CDC National Institute for Occupational Safety and Health
Tearing Clerk Food and Drug
;
Administration
.
JAN 2119741974
Lincctor tional tional Institute for
Occupation foty and calth calth
regulation on
cister particles the Federal
asbestosparticles of September
Pace
Pace tne
227707 07 772nd
paragraph 2nd full
Potente Setanta paragraph
ee
An additional reference could be included to describe the NIOSH
air sampling technique for asbestos Leidel FA et al USPP'S
NIOSH Membrare Filter Method for Evaluating Airborne Asbestos
Fibers R 54
DIEW published In press and
PPS
should be
NIOCH
Cincinnati soon
Ohio
It is now
,
are presented in
oversimplified in
wethod the
publicatiopunblication publication
be
give
is doubtful that the recommended technique
on the wiere slide mentioned in Section
provide a uniform particle distribution distribution .
It is expected
that
problems will be encountered when
that the sumple in
dispersed towartowards ds
that the particles the outer edges
the slide cover is placed over and liquid will tend to be
of the slide It is believed
more research is needed to ensure obtaining uniform particle .
dispersion
'
111)
The minimum number of slide fields or number of fibers per slide
that must be counted must be stipulated so that conversion conversion to fibers per milligram of sample can be calculated This minicum
at
et
+
soe
.
wee
outher depends depends on the statistics of
determined as in nection
fibers
above
number
sample sample sample
document
uniform distribution of particles
method The
for converting
mumber of fibers per milligram
from of
is donc in the NICON criteria
38 or in the previously mentioned
NOSH 84
should be dudict that
thethe
caples before and
drug be
fiber after
determinations chould be made on filter application since the
found
stipulated rather
asbestos form
The reference to the NIOSH
determine to
techniques
asbestos reducredutction ion described in that
the filers
adequate
sampling from air
those
criteria
reduction
criteria document on asbestos for methods
is not sufficient because the
document are for air sampling Once
subsequentprocedures are medium would be different than
liquid
different sampling procedures should
IIff
is
is
statement that there sshhallall be fiberfibesrs released into drugs that statement
wtehwerntrentstatemelntitelirteraly ally then phase contrast microscopy wernt
literally
literally literally
there then
there
the
criteria
use
be
no
no
phase
phase
of phase
fibers
released released
contrast
contrast
released
into
drugs
microscopy
microscpy
,
as
describe in TranenfosiTranenfosionoTranenfosion n
the Il criteria document is not oufficient electron microscopy would have to be used to ensure
that
procedures no fibers
acceptable are
are
released
released released
released
released
However
However , the
if you desire to staple
for
analytical procedures
fibers greater
than five
microns in length
ry
.
Marcus M. Koy M.D.
Ausictant Surgeon General
ORSD NIOSH
TRAB 1/17/74
.
Official file located in room 318