Document pm654npaV75VEJL1ZdpM2e66D

SHANGHAI HEALTH STUDY Jennifer Galvin, Ph.D. Chair, SHS Technical Committee Phone: 918-661-3865 Email: jennifer.b.galvin@conocophillips.com c/o American Petroleum Institute 1220 L Street, NW Washington, DC 20005-4070 Email: twerdokl@api.org Date: From: To: Subject: 28 January 2005 Jennifer Galvin, Ph.D., for the Shanghai Health Study (SHS) Technical Committee Dr. Richard Irons 2004 Year-End Progress Report and Revised Expense Projections Dear Richard: Thanks for recently spending time with the Shanghai Health Study (SHS) Technical Committee. You and Dr. Krieger explained the current situation with the Shanghai Benzene Research program in a clear manner, particularly with regard to exposure assessment, and provided a much clearer idea of the planned path forward. It would be useful to incorporate your thoughts on implementing the revised exposure assessment plan in your 2004 year-end Progress Report. While we recognize there are still uncertainties in this plan, we would appreciate sufficient detail to allow the Technical Committee to track progress, and also allow this information to be shared through the Progress Report with the SHS expert panels. For instance, we would appreciate a written description there of the envisaged Sector group exposure analysis and its relationship to the current exposure analysis strategy. Regarding the program as a whole, the budget discussion was very informative and we would also ask you to describe this in detail in the upcoming year-end progress report. We would like you to provide detailed information on item 2) expense increases, and item 3) total expense projections by year using the categories that you currently report in your biannual progress reports (e.g., personnel, operating expenses, subcontracts, travel, equipment & indirect expenses). The "post-study analyses" costs should be included in this more detailed expense projection. We need this information for two reasons; (1) to present detailed rationale for a request for increased funding, and (2) to develop a payment schedule for the remainder of the study, should additional funds be secured. Please see the attachment to this letter, to aid you in developing this required information for the year-end report. Cc: SHS Technical Committee SHS Oversight Committee SHELL-MCCLURG-057151