Document pm0Dx8Ex89M0Bj5qQ2Vy40m7a

InternCaolrrespondence To: From: Subject: Date: C" ERCIAL CHEMICALS ANALYTICAL REPORT #346 E. G. GORTNER - RIKER SAFETY EVALUATION - 218-3S-03 R. M. PAYFER - COMMERCIAL CHEMICALS - 236-28 FINAL EVALUATION OF FM-3924 (T-2999CoC) FOR RIKER STUDY NO. 0681TRO362 June 22, 1982 References: Commercial Chemicals Analytical Requests #16474, 18319, Analytical Report #318 A light, straw-colored waxy solid labeled FM-3924, Lot 547 was received for analysis for Riker teratology study #0681TRO362. The material has been analyzed with the following results: Gas Chromatography of Sample As Received All in Area % QC(14310 12/3/80 3/31/81 3/5/82 5/27/82 Inerts Amide C3 C4 C5 C6 C7,C8 High Boilers 0.5 10.6 for all low boilers 88.9 - 0.4 0.6 1.2 1.8 1.5 4.8 88.9 0.6 0.7 0.6 1.3 1.7 1.6 4.3 88.9 0.8 0.4 0.6 1.2 1.8 1.5 4.8 88.9 0.6 0.7 0.2 1.3 2.2 1.9 4.9 88.9 0.2 All values are within experimental and integration parameters. Values meet QC specifications. 2 Elemental Analysis c H N s F 0 by difference MW = 571 % Theor. % Found 3/5/82 25.2 1.75 2.45 5.6 56.66 8.4 24.6 1.5 2.6 5.3 57.0 9.0 % Found 5/27/82 25.0 1.8 2.7 6.1 55.3 9.1 Melting Point: Initial 38-480C Recheck 38-480C. 5/28/82 38-480C Spectroscopic: Infrared spectra 16474-2,3,4 and 18318-1 are identical to each other and match reference spectra. 16474-2 was obtained 16474-3 was obtained 16474-4 was obtained 18318-1 was o.btained 11/14/80 3/31/81 3/5/82 5/28/82. NMR spectra H8385, H8387, F8390, F8391 were obtained on 12/l/80 and 12/2/80. These were to confirm structure and not repeated. Structure was confirmed. The isomer distribution was found to be 69.6% straight chain, 10.9% (CF3)2CF branched, and 19.5% backbone branching. Conclusions: FM-3924, Lot 547 has an analysis within specifications,is stable and is representative c ercial material. RMP/hc dc: M. T. Case - 218-2 E. G. Lamprecht - 218-3 W. C. McCormick - 220-2E-02 W. H. Pearlson - 223-6SE-04 L. D. Winter - 236-2B