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PLAINTIFFS EXHIBIT ECC-19 Additional copies of this pamphlet and informational materials listed below are available from the Asbes tos Information Association/North America: -What You Should Know About Asbestos and Health"--an employee information pamphlet. Recommended Work Practices -- Fabrication and Use of Asbestos Paper Products -- Shop and Field Fabrication of Asbestos Sheet Products -- Molding and Fabrication of Asbestos Containing Plastic Products -- Fabrication and Use of Asbestos Friction Materials -- Use and Handing of Asbestos Textile Products "Federal Regulations -- Asbestos" -- a com prehensive handbook of regulations issued by Federal regulatory agencies. "Asbestos in the Atmosphere -- A hazard to health"? -- a general information pamphlet. "Asbestos in Water -- A hazard to health"? -- a general information pamphlet. Poster Series -- Asbestos Health Hints for the Workplace -- 15"x23" -- Vacuum dust spiBs... never dry sweep! -- When required, always use your respirator! -- If you don't smoke now, don't start If you do smoke, quit! -- Report unsafe conditions immediately! -- Repair broken bags immediately! -- Use change rooms and lockers! Leave dusty clothes at work! Poster --Recommended Practices for Handing Asbestos Fiber -- 11 ' x 14" NOMTM AMCftCA For further information: Asbestos Information Association/North America 1835 K Street. N.W. Washington. D.C. 20006 XF Handling Asbestos Fiber i i mein aagno 1446 Handling Asbestos Fiber Protection from fire, absorption of heat from friction, high tensile strength as a reinforcing material, resis tance to corrosion and insulation from heat, cold and noise are among the properties of asbestos that result m its use in hundreds of industrial applications and home products. Asbestos is the name given to a group of hydrated silicate minerals that are characterized by fibrous crystallization. Though asbestos is fairly common to the earth's crust,.not all deposits are of commercial value. Because asbestos is fibrous and, in a certain range of sizes, can enter the lungs, maximum care should be taken to avoid exposure to asbestos dust and the hazards to health that can result. GENERAL PRECAUTIONS In all stages of handing -- packaging, transporting, unloading, storing, and in-part moving --asbestos fiber bags should be handled carefully and in such a manner as to prevent damage of bags and the generation of dust. Damaged bags should be immediately repaired, re seated or put into closed receptacles. Any spillage of asbestos fiber should be cleaned up immediately -- either by vacuum equipment or, after thoroughly wetting, by sweeping -- and should be deposited in suitable closed receptacles. Consult and observe OSHA regulations governing asbestos in the workplace: EPA rules on discharge to the ambient air: and other local codes, rules or regulations controlling the handling and use of asbestos fiber. UNLOADING Unitized loads should be ifted intact to and from holds of ships, and off and on land transport by forkSft trucks or other suitable handling equipment. Care should be taken to avoid puncturing the asbestos fiber bags during unloading from ships, rail road cars, trucks or other modes of transportation. Hooks or other sharp instruments should not be used. Loose fiber accumulated during transit should be picked up by vacuum cleaner before unloading. STORAGE For storage, fB>er bags should be stacked and moved with care to avoid breakage; protected from punctire by moving vehicles; and. If possible, should be isolated from traffic in the warehouse and covered to prevent dust generation. To prevent deterioration of stored bags, the principle of first-in, first-out should be followed. HANDLING Maximum possible enclosure and fully effective dust control systems should be provided at all stages of in-plant handling where dust is created, such as in bag opening, fiber dumping and bag disposal oper ations. Loose fiber should be cleaned from work areas by vacuum cleaner, or after thoroughly wetting, by sweeping, and then deposited in covered recep tacles. PROTECTIVE EQUIPMENT Wearing of respiratory equipment approved for pro tection against asbestos dust should be required at all stages of asbestos fiber handSng where quantities of dust are generated which cannot be kept within the permissible exposure fimits by dust control equip ment or other methods. TRANSPORT Where the use of asbestos requires the transport of loose fiber in open carts or buggies, covers should be used to prevent spilling and dust generation. WASTE MATERIALS Waste materials, such as collected dust and empty fiber bags, should be placed in special closed receptacles and disposed of in such a manner as to prevent the release of dust. Safety practices outlined above in the HANDLING and PROTECTIVE EQUIP MENT sections should be followed during these operations. All dust from exhaust systems should be collected and safely disposed of, being careful not to release dust into the outside air. Particular attention should be paid to the protection of employees whose job it is to dispose of collected dust from fabric filter dust collection and similar cleaning operations. * i * i I j 1447 table drugs filtered through asbestos fitters. A measurement of the normal "background" level of asbestos fibers provides a means of com paring the levels in beverages, and drugs filtered through asbestos containing filter pads. Studies in the United States and abroad have consistently shown that the asbestos content of various soft drinks, beers, wines, and parenteral drugs is no more than and, in many cases, less than the natural background level of asbestos detected in water. u PreSminary results of a 1973 survey made for the Food and Drug Administration showed that the use of asbestos-containing fitters bears no rela tionship to the presence of asbestos fibers in the finished product** Thus, it is unSkety that the eimination of asbestos fitters in the production of par enteral drugs wiB result in any reduction in asbestos content of the finished product Governmental Action The Environmental Protection Agency has promulgated national waste water effluent stan dards for asbestos manufacturing operations to control the potential discharge of. asbestos bearing waste into our nation's waterways and publicly owned treatment works. The asbestos manufacturing industry in the United States par ticipated in the development of these regulations. In March 1975. the Food and Drug Administra tion published a regulation restricting the utifization of asbestos fitters In the manufacture, processing or packaging of components of drug products for parenteral injection in humans. At the same time, however, FDA reaffirmed a previous decision made in September 1973 that "promul gation of regulations on the imitations or prohibi tion of the use of asbestos filters for the prepara tion of foods and non-parenteral drugs ... is unwarranted until more reliable data can be ob tained concerning these matters."" SUMMARY 1. Asbestos exists naturally in small though detectable amounts in certain rock formations throughout the world and for millions of years has been released into the environment through erosion by wind and water. 2. The Advisory Committee on Asbestos Cancers of the International Agency for Research on Cancer has stated that evidence does not indi cate a risk of cancer resulting from asbestos fibers present in water, beverages, food or fluids used in the administration of drugs. Levels of asbestos found in beverages, drugs, etc., have not been demonstrated to be hazardous to human health. 3. The evidence for a relationship between heavy occupational asbestos inhalation and increased risk of gastrointestinal cancer is incon clusive. 4. There is no existing evidence of a relation ship between gastrointestinal cancer and drinking water carried through asbestos-cement pipe. 5. The asbestos content of various soft drinks, beer, wines and parenteral drugs tittered through asbestos containing fitter pads is no more than and in many cases less than the natural back ground level of asbestos that may be found in the world's water sources. REFERENCES 1. "Report of the Advisory Committee on As bestos Cancers to the Director of the interna tional Agency for Research on Cancer," British Journal of tnd. Modicine, VoL 30. pp. 180-186,1973. 2. "Report on Research at St. James' Hospital, Leeds. England" by LM. Swinburne, Appen dix 4,-including report from Asbestos Re search Council, October 1970-October 1971. 3. "Cancer Risk of Insulation Workers in the United States." a paper by I.J. Seikoff and E.C. Hammond presented at IARC Confer ence on the Biological Effects of Asbestos, Lyon, France, 1972. 4. "Feeding of Blue Asbestos to Rats" by F.M. Bonser and D.B. Clayton. 1967, Annual Re port. British Empire Cancer Campaign for Research, p. 242. v 1443 possible health hazard of drinking water conveyed tnrough these pipes. It can be assumed that, if there is a relationship between gastrointestinal cancer and use of asbestos-cement pipe, there would be an ncrease in the cancer rate as use of the pipe has ncreased. U.S. Public Health Service records show, however, that incidence of Gl cancer in the . United States has steadily declined though the j , usage of asbestos-cement pipe has risen signifi cantly.' tn a study of drinking water in nine cities that used asbestos-cement pipe for periods ranging from 8 to 17 years, not one of the water samples, either before or after passing through the asbes tos-cement pipe, contained fibers that were visible under a ight microscope. The highest asbestos content found in this study was 6 micrograms per gallon, about one five-milfionth of an ounce. This means that if a man were to drink eight glasses of water a day he might swallow a total of twentyseven ten-thousandths of an ounce (.0027) of asbestos in a ifetime of 70 years* * A special committee of asbestos-health experts convened by The American Water Works Associ ation Research Foundation reviewed all available data and concluded that the "risk to health from the use of (asbestos-cement water pipe) systems is small--approaching zero.'" Reserve Mining Case Perhaps the most widely publicized alleged health hazard from asbestos in water is the case of the Environmental Protection Agency vs. Reserve Mining Company. The case, involving the disposal of waste taconite tailings into Lake Superior, became a health issue when it was claimed that the tailings contained cummingtonite, said to be a form of asbestos. Many experts were called for testimony during the proceedings. The court appointed witness. Arnold L Brown, M.D.. Chairman of the Depart ment of Pathology and Anatomy, Mayo Clinic, Rochester, Minnesota, stated that there is no evi dence of an excess of cancer in Duluth, Silver Bay. or other North Shore communities anci further j testified: "Scientifically and.medically l see no evidence for an increased incidence of cancer in those communities that could be attributed to the presence of asbestos fibers in air or water.'** Early in the trial, the court ordered an extensive study of tissues from deceased persons in the Duluth area to determine the presence of asbes tos fibers. The study failed to disclose any asbestiform fibers which could have come from Reserve during the ifetimes of the subjects. The subjects had been selected by Court witnesses as repre sentatives. Only tissues from persons inhaSng Duluth air and ingesting Duluth water in excess of 15 years were examined." In a summary of medical testimony, before the Eighth Circuit Court of Appeals, it was stated: `There is no evidence that ingestion of asbestos in any amount has ever caused disease in anyone. Thus, there is no evidence that Reserve's dis charge into Lake Superior (whether or not such discharge contains any asbestos) constitutes a present or future Skeihood of disease.'"1 tn March 1975, the Court in its final rufing ordered the company to comply with aO air and water discharge regulations, but noted, "the evi dence is insufficient to support the kind of demon strable danger to the public health that would jus tify the immediate closing" of the facility. Asbestos Filters Minute amounts of fiber in some beverages and parenteral (injectable) drugs filtered through asbestos-containing filters have also been detected. It is difficult to determine whether the minute asbestos fibers in some liquids come from the filter or are already in the water. There is evidence that asbestos filters remove asbestos material along with other particulates. Asbestos-containing filters have been in world wide use for many years. It is reasonable to inquire if beverages or food containing electron microscope-size mineral fibers, including asbes tos. might expose large populations to a potential liealth hazard. Numerous studies have shown that, despite their long-term use, there is no evidence that anyone has ever contracted gastrointestinal cancer or mesothelioma from beverages or injec- 144d Introduction Water supplies in various sections of the world contain infinitesimal amounts of asbestos fiber, along with other particulate matter. The fibers come primarily from natural sources, and secondly from man's activities, including the mining and milhng ol asbestos-bearing rock and the manufac ture. use. and disposal of some asbestoscontaining materials. Inhalation of excessive quantities of airborne asbestos fiber in occupational settings is known to increase the risk of respiratory disease and certan types of cancer among industrial workers. There is also an indication of an increased inci dence of gastrointestinal (Gl) cancer among these workers. This has led to speculation as to whether the general pubic is subject to a health risk from the small amounts of asbestos fiber that may be found occasionally in water. In its report issued in . 1973. the Advisory Committee on Asbestos Can cers to the Director of the International Agency for . Research on Cancer, a division of the World Health Organization, stated that no evidence exists which would support the existence of an increased risk of cancer resulting from asbestos fibers present in water, beverages, food or in the fluids used in the administration of drugs.1 Since the discovery of the risk to health from uncontrolled fiber, the asbestos industry has com mitted itself to the safe handing of the remarkable _ mineral in the workplace and to control its opera tions to eliminate the release of free fibers into the environment. A separate AIA/NA pamphlet dis cusses asbestos in air. This pamphlet is ad dressed to the issue of asbestos in water. Asbestos Serves the World Asbestos, used since antiquity, has widespread and important applications in our modem tech nological society. Because of its remarkable re sistance to fire, heat, friction, and corrosion, approximately 3.000 different products containing asbestos, ranging from pot holders to brake linings, from asbestos-cement pipe and building materials to packing and gaskets are in daily use throughout the world. In the vast majority of these products, the asbestos is *'locked-in" with cement, resins, or other binders which restrict fiber release during normal handling or use. In 1974, nearly 850,000 tons of asbestos, primarily chrysotile from Canada, was used in the United States. Worldwide production is about 5 million tons. Gl Cancer and Asbestos Exposure Both human evidence and animal experimenta tion regarding a possible relationship between excessive asbestos exposure and an increased risk of gastrointestinal cancer is scanty and con tradictory.1 Some researchers have reported higher-than-normal rates of Gl cancer among in dustry groups heavily exposed to airborne as bestos.' Several major animal feeding experi ments, however, produced no tumors in the Gl tracts of the animals, even though the amounts of fiber fed to the animals were massive when com pared with human occupational exposures known to result in respiratory disease.* While some injection experiments have pro duced site and mesotheEa! tumors in test animals, the amount of fiber used in each case was so large as to render any attempted translation to human experience inappropriate. The studies strongly suggest that development of cancers in test animals is directly related to dose and. even more importantly, to the size of the fiber used in the experiment. Electron microscope-sized fibers (less than 5 microns m length) did not produce tumors in test animals.5 Medical opinion on the subject of gastrointestinal cancer and heavy occupational exposure is divided. Some experts consider the evidence in conclusive while others believe that only a "small risk" may exist. * Asbestos-Cement Pipe Asbestos-cement pipe has been used to convey potable water for more than half a century in North America. Europe and other parts of the world. The question has been raised as to the 1450 5. `The Locus ot Pathogenicity of .Asbestos Oust" by P. Gross. Archives of Environmental Health. Vol. 27. p. 240.1973. 6. "Asbestos: The Need for and Feasfcifity of Air Pollution Controls," National Academy of Sciences, Committee on Biologic Effects of Atmospheric Pollutants. ISBN 0-30901927-3,1971. 7. "Asbestos-Cement Water Pipe and Health" A/C Pipe Producers Association, Washing ton, D.C.,p. 4,1973. 8. "A Study of the Problem of Asbestos in Water," The American Water Works Re search Foundation, American Water Works Association Journal, Sept. 1974, p. S. 9. "Asbestos-Cement Water Pipe and Health," A/C Pipe Producers Association, Washing ton. D.C..p.3.1973. 10. From testimony by Dr. Arnold Brown in Federal District Court as quoted in Con gressional Record, Jan. 29,1975, p. S1179. 11. From testimony in Federal District Court as quoted in Congressional Record, Jan. 29, 1975. P. S1180. 12. "Asbestos Fibers in Beverages and Drinking Water," by A.M. Cunningham and R. Ponte fract. Nature, Vol. 232, p. 332-333.1971. 13. Report to Food and Drug Administration by ' Mr. Philip McGrath, July 10,1973. -14. Report to the Acting Director, Bureau of Drugs by Dr. J. Richard Crout, 1973. 5. Federal Register, March 14,1975, p."t 1867;- Asbestos in Water = A hazard to health? ( Additional copies of this pamphlet are available. Asbestos Information Association/North America 1660 L Street. N.W. Washington. D.C. 20036 A 1451 Additional copies of this pamphlet are available. Asbestos Information Associalion/Norlh America 1660 L Street. N.W. Washington. 0. 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"Asbestos in Water--A hazard to health?" 15c each Quantity. Handbook--"Federal Regulations--Asbestos" $5.25 each Quantity. Poster Series--"Asbestos Health Hints for the Workplace." 15"x2S" in various colors. Available at 40c each or complete series at $2.40. \bcuum dust spills^, nervsrdiy sweep! a Quantity MHMI* Report unsafe conditions immediately! WheniU required, always use your respirator? Quantity --------- Repair broken,< t-S immediacy! fiyoudon^ smoke now don't start. Iiyoudo Csmdkf, <j/.T..'sY Quantity wm-Ti- Usechange rooms and lockers! Leave dusty a,%. clothes \`A` - atworit! f Quantity Quantity Set of Six Posters Special Mailing Instructions: Quantity (Quantity) (Company) 1454 (Signature) To: Executive Director Asbestos Information Associalion/North America 1745 Jefferson Davis Hwy. Crystal Square 4, Suite 509 Arlington, VA 22202 (Date) Please forward the information materials noted below. We understand that we will be billed for costs plus shipping charges: "What You Should Know About Asbestos and Health." Employee infor mation pamphlet. 5"x7" 15 c each. Quantity IfcrtniimnvTiftyf IB? SSaKStww Handling j= AsfteaosSr3______ RberasHcj* jaasgsawi "Recommended Practices for Handling Asbestos Fiber." Heavy coated stock poster, ll"xl4" printed blue on white for employee information boards. 25c each. Quantity Also available in 3*A"x9" pamphlet form suitable for mailing in #10 en velope. 10c each. Quantity. Booklets--Recommended Work Practices--$1.35 each "Fabrication and Use of Asbestos Paper Products" Quantity_______________ "Shop and Field Fabrication of Asbestos Sheet Products" Quantity_______________ "Molding and Fabrication of Asbestos Containing Plastic Products" Quantity_ "Fabrication and Use of Asbestos Friction Materials" . Quantity!] "Use and Handling of Asbestos Textile Products" Quantity--------------------- -______ IQOO IREV PP0r--S/7t - OVER