Document peYBKooxKg9vL4mdovzZ5dY1w

f> fc y' ,T>%1 4. 'VK A*w f 2Z_ AN' ACXRFOKM DI.CKMATJ.: KG0S1S JACK W. JOXP.S, M.D. A N II HPKIJKRT S. ALDIlX, M.D. .vw..\vt.v, r,.\. I' Jl is only within comparatively recent times that the dermatologist has inlcresied himself in dermatoses associated wills or caused hv the daily woik. \\ ith the advent ol a more dearie dclmcd apprnNrd .if die words eczema and dermatitis and the move general ik ol the patch test, der matologists ha\e mcessunly ini|iiired more ami more detplv into the inmmtcrahle chemical contacts that occur in the day by dav lives of their patients. As well as being conversant with detmatologv, the der matologist must have a working knowledge of the manufacture and content of the many new and old compounds that arc handled and applied by large numbers of persons. Hence, more and more derma tologists arc becoming industrially minded, and it N dawning on them that the solution of some of their industrial difficulties mar aid them in a cleaier conception of the dermatoses that aic cneuunkrcd in their everyday practice. IXnnaUTgoscs of the ncueform type occurring in prisons working with chemicals have hevo repeatedly reported in Kuvope ami discussed as industrial "eldor-acne." 1 This term "chlur-acne" was first used In ] ferxheituer in 1899 to de-erihe an eruption composed of comedones ami small sebaceous pustules that occurred on the amts and faces of wankers manufacturing chlorine gas eleetrnlyticallv. using cavUm electrodes. It was natural to assume that the chlorine was the calmative agent. Bellman had observe*! in March 1897 two patients whose shin> were dilfusdv pignietue<l. dark, rough ami dry. in whom were observed small tenacious comedones associated with numerous small follicular abscesses. SubsequentIv he reported twenty-one additional cases with similar symptoms in workmen who were engaged in cleaning out an acid tower used in the manufacture of hydrochloric acid, At no time did these men come in contact with tree chlorine, hut mtinemus loose Read at tin* Pi*tv. Kifd'lk Animal Meetimj the Amcriran Dvr,natili'j*ii,al Assinialinn. |ne.. White Sulphur Springs. \V. \ a., M.tv 2, IVJ.v J. While, Pr'>*er: The Dermalu cows. <<!. J, New Yoik. Paul H. I|icl*er. Inc.. l`>34. 2. 1 lo xhciincr: Miincltn*. mod. Wthnsdir. 4G:'7S. ISW .1 bellman: Deutsche nted. Wchnsthr. 27:437. 1901. MQNS 0978Z1 JOXl-.S-Al.lll.X --. Il'.\ l:l'( 1 l\'M i)t:k\I.\i /:7v\,(/.w.> lu:; Of ilu* twenty-four men working in itie manufacture of chlorinated <li-phem! within I he period fiom Ilu* late summer of VJSZ lo October, 19,>.k twentv-threc were reported to have had an acnefonn eruption on the lace atul body. Of the twenty-ihree. sixteen were examined. These men presented eruptions of acnefonn chaiacier similar m type and distrihulion Lo that in the case referred to hut varying in severity liable). In mam patieuls numerous small sebaceous abscesses developed, par ticularly around the collora line, which exuded heavy, tenacious pus. clKinfitf* i the I pig. 2.--Characteristic apiu-arfmce ami tncMimi oi mi acmnurm eruption. and the remaining- ulcers were indolent, leaving in their wake much scarring. In two of the cases particularly, many large ab-eesscs developed on the neck and hack. Until verv recent times di-phenyl and chlorinated di-pheml were only laboratory curiosities, atul their commercial manufacture was unknown. In the experimental stage of manufacture the apparatus was necessarily crude, and experimenters am! workers were exposed Imr long periods to fumes :md dusts containing much chlorine, both free ami combined. In the early experiments, as well as in the early manufacture in large -mil ...... ^ i.y 1 'Ti'jj~ 11. I MUNS 0978^8