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Industrial Hygiene Digest - 19 January, 1950 '57 Pigmentary Disturbance Following Exposure to Monobenzyl Ether of Hydro- . quinane. B.J. Bernstein and P.M. Sachs. Arch. Dermat. & Syph. 59 , p. 542 (May, 1949). ' .In 1940 Schwartz and associates reported deplgmentatlan secondary to 7 the veering of rubber gloveb . She leukoderma vas traced to monobenzyl ether of hydroquinane, an antioxidant used in the preparation of the rubber.-Ibis report presents four cases of this disorder, those of three negroes employed In the manufacture of rubber dolls and of a vhlte ., man exposed to neoprene. In the four cases manobenzyl ether of hydroquinone vas employed In the preparation of the rubber. Hone of the patlenta had previous disturbances of this nature. Patch tests of substances to. vhlch the patients vere exposed gave positive reactions only to manobenzyl . ether of hydroquinane. The three negro patients exhibited depigmentation, vhile the vhlte man shoved hyperpigmentatIon. Other cases vlth similar Involvement, In the same plant na elsevhere are known to the authors. TTonoceupatlanal origin of this depigmentation has . been observed In the use of rubber pfoductB. In same caseB the pigmentary disturbance vas.preceded by. Inflammation. Elimination of oontact vlth the rubber vas followed by restoration of the pigment. -- Condensed from Arch. Ind. Hyg. & Occ. Med. 58 Dermatitis in the Making of Chocolate Candy. M.H, Samitz, Occ. Med, and Surg. 19, 35-3*> (January, 1950). (l) Descriptions of.the types of eruptions prone to occur among choco- late workers In candy factories vere reviewed. (2) The mechanism In the production of these eruptions vas explained. A case of furunculosis and folliculitis In a chocolate candy worker vas reported, and the Importance of understanding the mechanism responsible for these Infections vas stressed. Such knowledge will enable the expert physician to establish the criteria necessary for a diagnosis of a case of Industrial dermatitis. -- Author's Summary and Conclusion Chemical Hazards' 59 Tabulation of Toxicity Classes. H.C. Hodge and J .H-. Sterner. Am. Ind. Hyg. Assoc. Quart. 10, 95-96 (Dec. 1949). , This report summarlzes-the- discuss Ions of the Toxicological Bound-Table during the past three years an standardization In toxicological terminology and In methods fif testing. The proposed terms for ranges of toxicity are: (1) extremely toxic; (2) highly toxic; (5) moderately toxic; (4) slightly toxic; (5) practically nan-toxic; and (6) relatively harmless. Roughly as a suggestion, the amounts of substances In each class that would be lethal to man are; (l) a drop or grain; (2) a teaspoonful; (5) an ounce; (4) a pint; (5) a quart; and (6) mare than a quart. A chart Bhovs the relation ship on a logarithmic scale vlth metric quantities. It Is proposed to establish separate scales for oral and intraperitaneol administration. Inhalation, and skin application, vlth tabulations for different animal . species. Shaft+thBles are given, with a few substances classified, far : each method.