Document pe9p4B1xwgKzwe5V25Va1MwzX

R3 3M + 3M Emironmental Technology PRO BoNx 33331sam asi 7I8 a2 AR226 _ 1095" 8 mLL 51263 May 10,2002 Document Processing Center (7407) OfficeofPollution Prevention and Toxics U1.2S0.0EPnevninrsoynlmveanntiaalAPvreontuecetiNonWAgency Washingion, D.C. 20460 FYI ORPEPCTEICVBEID A02JUN~4 AH): 1 - 0k02_01378 Attention: For Your Information Docket - Docket No. AR-226 Re: Information on Perfluorooctane Sulfonates and Related Compounds Dear Sir or Madam: `rTehliastecdonctoimnpuoeusn3dMs',savsoplaurnttoafryousrubomnigsosiinognsdoifadloagtuaeownitpherEfPluAorroeogcatradniengsufllfuoonraotcehseamincdals. 8 & 2o Enclosed you will find the following supplement to the Two-Generation Reproduction ~~ = "303 Study of Ammonium Perfluorooctanoate in Rats submitted previously to the docketon ~~ im ALparbiolra2t,o2r0i0e2s:, MaFyina1l, 2R0e0p2o.rt, Protocol 418-020, Argus Research, Charles River == 3335 Trehperoednuccltoisoend/ddeovceulmoepnmtendteaslcrsitbuedsyiwnidtehtaaiml mthoenciouvmarpiearnfcleuodraotoactfarnoomatteh.e tTwhoi-sgeannearlyastiison~~ &. `was undertaken in an attempt to understand the degree to which certain effects seen in the F1 generation (delayed sexual maturation, post-lactational mortality, and increased estrous cycles) could be explained by either gestational age/maturity or body weight of the animals. ATE" HAAR `coWnetawicltlmceonwtiitnhueantoypqruoevstiidoensi.nformation as it becomes available. Please feel free to nodf, iG ] AT STA Michael A. Satoro Director of Environmental, Health Safety and Regulatory Affairs Specialty Materials Markets 3St.MPCaeunlt,eMr,NBui5l5d1i4n4g 236-1B-10 665511--773333--61397548 (phone (fax) ) E-mail: masantoro@mmm.com FY1-00-001378 CONTAIN NO ca Ecnec:. Dr. Charles Auer Dr. Oscar Hemandez I ooEoonnnIe