Document pbrz60oVpJwwNZ8Ramrmg97B

July 23, 1969 Nr. A. Bruoe Pyle Assistant Bursau Chief Department of Conservation and Xoonomlo Development r. 0. Box 1609 Trenton, Nee Jersey Dear Nr. Pylei Xn eonneotlon with your recent request for more speolflc Information on FCB, X have enelosed several ltema that aiay be of Interest. The flret le s table showing the physloal characterlatlos end properties or our Aroclors, the trade name for our polychlorinated biphenyls. The numerloal designation of these materlale Is mean ingful. The 1200 series era biphenyls ohlorlnated to the extent Indicated by the last two numerals, For example, Aroclor 1242 la biphenyl ohlorlnated to the extent of 42Jf Aroolor 1234 Is biphenyl ohlorlnated to 54jt. The 5400 series are terphenyls ohlorlnated to the extent of the last two numarale. Thus Aroolor 5460 Is terphenyl ohlorlnated to 600. The 2500 and 4400 materlale are mlxtarea of biphenyls and terphenyls ohlorlnated to 65J(.; We have typed on the bottom of the table the results of aeute toxlolty studies. These lndloate the approxi mate lethal dose In ruts when administered orally and the minimum lethal dose when the samples ware applied ' to the unbroken skin or rabbits. Tou will note that the samples were administered undiluted or as various con centrations In corn oil depending on the physical form and solubility of the sample. MUNS 090796 Mr. A. Bruca Pyla July 23, 1969 P41 Two Tha aaoond anoloaura rafara to tha only pubAlahad data that w now hava oonoarnlng poaaltila toxicity to flah. Thla anoloaura la a 1957 raport from tha U. 8. Plait and Wildlife Sarvloa ahowlng tha raaulta of atudlaa to determine tha poaalble effaota of ohamloala to larval lamprays and flahea. Tha anoloaura inoludaa a oopy of tha tltla page, tha paga explaining tha table and that portion of tha tabla whloh lndloataa that four of tha Aroolora hava no affaot on trout, blueglll and larval lampraya at a oonoantratlon of 3 ppm In a 24 hour taat period. Tha only ohronlo toxlolty data that wa hava rafara to tha Inhalation of vapora of Aroolor 1242 and 1254, Inoloaura thraa la a raprlnt deaorlblng tha ohronlo Inhalation atudlaa and anoloaura four la a Hyglana Oulda publlahad by tha Amarloan Xnduatrial Hyglana Aaaoalatlon whloh praaorlbaa aate handling taohnlquaa for tha uaa of thaaa matarlala In lnduatry. Baaad on avallabla data, manufacturing and uaa exparlanoa, wa do not ballava tha polyohlorlnatad blphenyla to ba aarloualy tcoclo. At tha aaaa tlae wa hava alao raooaaended praoautlona to avoid rapaatad and prolongad akin oontaot and aaoondary avoldanoa of Inhalation of vapora whan tha aatarlala ara haatad. Aa lndloatad by tha dlatlllatlon rangaa In anoloaura ona, thaaa produota hava axtraowly low vapor praaaura and thua praaant llttla vapor Inhalation haaard at aablant teaperaturea. X don't know that X oan add a groat daal to your quaatlon to tha uaa of thaaa aatarlala without rapmating tha ooaawnta In tha atatoaant whloh To* Pord aant you. Thair dlalaotrlo oharaotarlatloa load to uaaga aa lnaulatlng flulda for tranafonnera and eapaoltora. Tranafomar applloatlon la in alaaa appllaabla to aub-atatlona rathar than tha amall tranafomar on llnaa for raduolng voltaga for houaahold uaa. Tha plaatlolaar typa applloatlon FCB'a am lnoorpomtad Into a polyaar aa an lntagral part of tha aolld aatorlal. Thla la tha oaaa whathor tha polyaar la than uaad .aa an adhaalva apaolal alaatoaor or Individual aurfaoa ooatlng. Contrary to aona raporta from tha praaa, tha POB'a am not uaad In rubbar tint, llpatlok, or tha ooaaon plaatlo oontalnara or fllma uaad for lnduatrlal or houaa hold paokaglng. MONS 090799 Nr. A. Bruo* Pyle July S3. 1969 Pag* Thr** We hav* a oonalderabl* r*a*areh effort underway to determine the toxlelty of aeveral of the POB'a in rata and doge. He are alao inoludlng three genera tion reproduction atudlea In rata. Alao underway are atudlea with fowl to determine the poaalbl* ohronlo effect on the bird* theme*It**, egg alee and production, hatohablllty of the egga and via bility of the ohloke. V* will alao do atudlea to determine any poaalbl* affeot on agg ahell thlokneaa and calcium and phoaphorua metabollem. Ve hav* attempted to eatabllah a program for deter mination of the poaalbl* biodegradation of tha polyohlorlnated biphenyla but raaaaroh of thla type la not yet underway. Ha-amphaalalng a point we attempted to make In the atatament Tom aent you, wa are unable at thla time to oonoaive of how the PGB'a can became wide epread In the environment. Zt la oertain that no applica tion* to our knowledge hav* been mad* where the PCS'* would be broadoaat In the aam* faahlon aa the chlor inated hydrocarbon paatloldea have been. X am aura there will b* much more raaaaroh undertaken to olarlfy aowe of the queetlona that aarly raaaaroh afforta have ralaed and you nay be aura that wa will partlolpata In a number of theaa. Zf Z oan be of any further aaelatano* after you have reviewed thla letter and tha anoloauraa, plaaa* let me know. lnoerely. WWlJu liner P. Wheeler Manager, Bnvlronnental Health MUfcS 090800 X' '