Document pZw8NR66pny2157VmqRxq3pD
FILE NAME: Foseco(FOS) DATE: 1965 Aug 10 DOC#: FOS008 DOCUMENT DESCRIPTION: Unpublished Internal Report
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HIGHLY CONTLSgreiAL
10-th Au^us t *.9 =5
S ilic o sis
and A s b e s t o s e s os.cg.rd a A s s o c i a t e d w i t h ar.d Pa a o f P r e ta x .
"he Mamf c c curs
A uthor;
C. rfaahbourna, 3. So.
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Syr.oneis :
E s o s a t l i t e r a t u r e o r d i s e a s e s o f th e iu rs -s b ro uo by o cc u p atio n al exposure to s i l ic a ard asbestos d u sts has s u r v e y e d , en d d i s o u s s ie n s cr. r e c e n t d e v a lo p r a r t a h a v e bee w ith c e a b e r s o a a e d i c a l r e s e a r c h u r .it o p e r a tin g i n th e K irgdcn.
h s n e c h a r i a n a c a u s in g t h e s e d i s e a s e s a r e d i s c u s Bed. ,B n a t u r e sn d a r t e r t a th e b a s e r da a s s o c i a t e d w ith r r t i e r 10 ara co r.eid ersd , and i t is concluded th a t the ra ru fa c c u r e and use t th is r a t e r i a l i t s r o t e n tire ly w ith o u t r is k . Hears of c sv ia c i thee 8 haesrds are recem en d ed .
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ISTROBCCTIOfl
S n q u irie B a re 1531112 r e c e iv e d i r o n c u s to n e r s r e g a r d i n g the p o s s i b i l i t y o f i l l n a a a among ste e lw o rk s p e rs o n n e l a r i s i n g from th e long-term use of P rofor 10. O bjections t o ' a p o saib lp a ilic o a i3 h a s a rd have 10011 a r i s i n g d u rin g n e a r l y th e 'hole p e r io d i n w hich P ro fa x has been m ark eted , and i t has been n e c e ssa ry in some ca3e3 to use o liv in e an a f i l l e r in s u b s t i t u t i o n f o r s i l i c a f l o u r . More re c e n tly , f u r th e r o b jectio n s have been re c e iv e d re g a rd in g a p o ssib le ash e sto sia hazard and ito asso c ia te d danger of cancer of the resp irato ry tra c t.
The m a t e r i a l i n t h i s r e p o r t cornea from a s u r v e y .of r e c e n t l i t e r a t u r e on d is e a s e s of the lungs and c h e s t caused by exposure to to x ic duat3, and from co n su ltatio n s w ith re p re se n ta tiv e s of the Pneum oconiosis R esearch U nit of the M edical R esearch C ouncil, Llandough H o a p ita l, P e n a rth , G lam organshire. The in fo rm a tio n gained has been used to i l lu s t r a te th e p o ssib le r i s k of pulmonary d iso rd ers accompanying the m anufactura and use of P ra fsx 10, and as a b a s is f o r c o n s id e r in g ways of re d u c in g o r e lim in a tin g th i s r i s k .
Comments on i n d u s t r i a l h y g ie n e r e g u l a t i o n s and th e l e g a l aspects of s ilic o s is re fe r to S xitiah p ra c tic e . D ifferen t re g u l a t i o n s may e x i s t i n o th e r c o u n trie s-, an d i t i s s u g g e s te d t h a t th e reader should fa m ilia ris e him self w ith those.
SIDXCOSIS
D e s c r ip tio n o f t h e D is e a s e -.
S ilic e a ia is a disease of the lungs caused by b reath in g a i r c o n ta in in g imcomhined s ilic o n dio x id e d u s t. I t produces nodules of fib ro u s m a te ria l w ithin both lu n g s, and can be d etected a t an e a r l y s t a g s by X -ray e x a m in a tio n . The d is o a s a may r e a c h a s e r i o u s s ta g e b e f o r e p ro d u c in g c l i n i c a l sym ptom s. The m ost common symptom of se v e r s i l i c o s i s i s s h o rtn e s s o f b re a th fo llo w in g e x e r t i o n , and t h i s symptom may in c r e a s e t o th e p o i n t o f c a u s in g co m p lete d i s a b i l i t y . B ow avsr, a m ild to a o d a r a ta d e g re e o f s i l i c o s i s may accompany an o th erw ise ap p aren tly normal s ta te of h e a lth . A p e r s i s t e n t cough. a n o t n e c e s s a rily an e a r ly m a n ife s ta tio n of th e d i s e a s e . When t h a d i s e a s e h a s re a c h e d th e s ta g e whara i t c a u se s shortness of b re ath to a disabling degree, there u su ally follow p ain in th a -c h e a t, lo a s o f-a p p e tite , in c re a sin g fa tig u e and w eight lo s s , e v e n tu a lly s h o rtn e s s o f b re a th even whan r e s ti n g , and f i n a l l y p o s s ib ly d e a th from p n au a o n ia , h e a rt f a i l u r e or tu b e r c u l o s i s . Tha damage caused by s i l i c o s i s is i r r e v e r s i b l e , and the d is e a s e has ban observed to progress a f te r exposure to s ilic a duat has been term inated. I t is g en e rally baliavad th a t tha disaaaa reaches its
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t u b e r c u l o s i s . h r p e r i n e r t s cn a n,iinr a l as hb av ea shown t-thhaat th,a v i r u l s r .o s
id t u b s r o l e b a c i l l i i s
when t h e y a r e e--cw rng 4^ a s a l i c e t i :
.ung; dio w e v er, n o d a r n
ios s i b i a t h a p r o t e c t i o :
.ad a o t i c n . T h e r e f o r e , s i l i o o - t u b a r c u l o s i s i s s. p r e v e n t a b l e and id te n a ar a b i a d in a s e a .
I n a one o a s e s t h a v i c t i u ia e n t i t l e d "by law t o a cap a n - . s a te e n . I n any le g a l p ro c e e d in g s in. th e U n ite d Z ingdcn in v o lv in g \ c la in a d o r c c n p e r s a tio n , th e d is e a s e ia o n ly d ia g n o se d when a l l th e d c lic k in g c r ite r ia have been s a tis f ie d :
1)
X -ray a x s rin a tio n shows s i lic o s is shadows.
2)
T hera is a r e l i a b l e h i s t o r y cd p ro lo n g e d expos e ra (n e rs
t h a n 10 y e a r s ) t o r a s p i r a h l a s i l i c a p a r t i c l e s a t c c n o e n -
t r a i i c n o i n a x o s s a o f th a l i n i t a l a i d down by H.H. T a s tc ry
"xSyt
-Inapaotorate '
3)
B re a th in g d i s a b i l i t y n n s t be d e n e n s tr a ts d , and a l l c th s r
Cannes d cr th e X -ra y a b n c m a lity a lir d n s ts d .
liechanisn of S ilic o sis .
hr eath ed 4...M Z~9
l u n g s a n d b r e a t h e d o u t a g a i n , p r o v id e d t h a t t h ,ey do n o t tench lh;
cd th e s u r ia n a s cd th e lu n g t i a s u a . c a n t , a n d a n y p a r t i c l e c c n d n g d 0.M
However, tha lung tissu e Is T it" w i l l ba ca .. -W
and r a n a in in s id e the lu n g . C le a rly , th is e itu a tio r . o cu ld n o t ba
a llo w e d tc c o n tin u e d o r any l e n g t h cd t i n e , o th a rw is s th a lunga
w ould baoone b locked up w ith d c re ig n n a t t e r end ceaee to d u ra tio n .
T here a r e two n e c h a r is n s a t p la y i n r a d r y in g u m rs rto d n a t t e r d re n
th a lu n g s . Tha wind p ip an d th e w id sr a i r paaa& gea a t tha u p p ar
an d cd th e lu n g a c o n t a i n w h a t a r e crown as c i l i a r y t r a c t s , T his
n s e r a t h a t th e a a 11a c c n p o s i n g t h a t i a a u a '-`- g th a a a tu b e b e a r
" ic r o s o o p io , h a i r - li k e p ro tu b aren a aa whioh b a t back and d e rth in
m y th - w hich produoas waves o novanant upwards .alo n g a rdanos c-dJ* t hUe a i r t u b s . Thidiis a c t i o n i a t a m e d " r t i c b r o r a l n h y th n " and
e sn be li k e n e d to th e r e v o r a n t od a n i l l i p e d a 's la g s o r to
c- g u s t cd w in d b lo w in g a c r o s s a o c r r d i a l d . Eh a d d a o t i a t h a t a
rsry th in d iln
n u s u a z. e e e t i e auaall!l y j r n p i t d r : th a Lowe:
u p p e r p s n is cd th a a i r tu b a s and o v o n tu a lly e n te r s th e co u th ,
t o g e t h e r w ith f o r e ig n p a r t i c l e s tra p p e d i n i t , w h irs i t can be
cc: tua c -
r 25-23-2233-0355
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is su e r a a s In the lu n g s whars tre y are d isp o se d o f.
E lis n e c ia r .is r goes wrong when a s i l i c a p a r t ic la is in g e s te d by a phagooyta . The su rface c f th e s i l i c a - p a r t i c l e r e a c ts w ith su b sta n ces in s id e the phagocyte to fe r n te x io products which i h i l l th e phagocyte and are r o la a sa d when i t d ie s . The c a lls of the' ly rp h o id '-tissu e ara p o is o n e d by thsse to x in s and r s a o t by baocning f ib r o u s . The a i l i c a p a r t io l a la r e le a s e d by tha break-up of th e phagocytB, and oan be r a - in g e s t e d by another p h a g o cy te, and bo-cr., baing c o n t in u a lly r e c y c l e d . IThan tha ly s p h t i s s u e b e a o sss fib r o u s , the norm al p assage o f p h a g o cy tes is o b s tr u c te d , sued th e y nay then nigrate through the' frails of lyrph v e sse ls and d ep o sit th eir s i l i c a co n ten t in thB g a s -e x c h a n g in g t is s u e near b lo o d v e s s e l s . This l a t t e r tissu e responds very q u ick ly to tc r io n a t e r ia l, and produces large q u a n titie s o f fib r o u s .n o t a r ia l, producing tha ty p ic a l nodular f i b r o s i s w hich oan be s e e n b y X -r a y s. The b lo c k a g e c f th e iy r p h a tis drainage systan by fibrous" tissu e nakea i t d if f io u lt for the lungs to dispose of fu rth a r fo reig n m aterial; th is fact-probably explains tha in creased s u s c e p tib ility cf a ffe c te d lungs to such iofeotion s as tu b ercu losis.
r e m i s E i b l a S u s t Con c e n tr a , t i e r s .
The c e x p o s it io n o f T ro fa r 10, and th e g e n e r a l circum stances of i t s E sruiactura and use, w ill give r is e to atreatherde dust c o n o e n tr a tie r s approaching and p o s s ib ly e r o e e c in g the Limit
su g g e s te d by th e h i n i s t r y o f L a b cu r." ( Z s f . 1 . ) Tha fig-ores quoted by the Ifi n i s t r y cay be -en p loyed as a u s e fu l g u id s , but th ey do n o t n e c e s s a r ily in d ic a te d u st l e v e l s which p r o ffe r c o u p le ts freedom f r o r the p o s s i b i l i t y c f s i l i o o e i a . Ko auoh c l a i u i s nade by the iid n istry , and th e ir fig u r e n are derived fro n jUosrioan. opinion baaed on bc a n ty oan a h i s t o r i e s and ar-ira-l t r p e r i r s n t a . T u rth errcrs, tha a ig n if ic a n o a c f the M i n i s t r y ' fig u ra a i s g r e a t l y weakened by tha fa c t th a t no n e th o i o f d u st a n a ly sis , la d no rang* c f p a r tic le s i z e s , ere s p e c if ie d . Thus, tha lim itin g * fig e r a > oou ld in clu d e air-borne p a r tic le s of any s iz o , in c lu d in g those which are u r lik a iy to enter or be r e t a in s d b7 tha lu n g . "Tha ic a r c it y o f i r f e r m a t i on a r is e s
* T orsshold l i r i t fo r cu artz-an d c r isx o b a lita -b e a rin g dusts
250 + ( SiC j * 5) m i l l i o n p a r t ic l e s par o u b is f o c t , or
2=25
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1 c ir c le s , tr d i t would soon th .it the p o ra rtfs.i dangers c f cr c rid c lita
a r a- n o : -f u l--l-yV r*e--a---li%CsfcVe d . A---r-i-r-a --l_ ve x pwe^r i~r--a r c- s r...a..d i a--s-----t"o* "1u ~ wc--hVg A4'sJsu r e a sso c ia te d w ith blue a sb esto s ir e vary r s e l, tad th a t tha standards cf in d u s tr ia l hygiene req u ired for handling th is n a t e x ie l nay avartu s l l y be ocn p sracle. irith t h e s e f cr h a r y lliu r and i t 3 c c r p c e r a
C arcir.cnata. have b e a r found ir. the p le u ra ci' parscr.s eh: had pear, Exposed only o c c a s io n a lly to Ic e ochoantrati.snfa' c f blue
a s b s E to s d u s t . 2 x t r s r o r.aoaa shew ed o a n o sr d a v a i o p i r a up t o 5C ysara s f t a r a s in g le e x p o s u re . She H re u rb o c rio sis P.asaarch. U n it have d sta o ta d a v ery th in f i l s of poly cy o lio hydrocarbons on tha surfers cf b lu e aa b B sto s f i b r e s , , an d a n a ly s i s ahorra t h a t t h i s l a y e r co n tain s o ax c in o g e ric au b sta n o a s w hich i t is baliav& d nay be ra a p o n s ib ls fs r t the unique a f f e c t o f th is n s ta x is d .
Perris s i b le Dust Cor.oentrg.tiors.
I t t r i l l be obvious ir o n the fora g r in s aa c tio n c f th is
rep ert th a t no exposure to blu e asbestos dust oan be to le r a te d ,
horevar low th e co n cen tra tio n end however sh o rt the d u ra tio n cf
exposu re. However, i t nay ba prsauaed th a t d u rin g th a i g n it i o n cf
Prcfax tha Carcinogens in tha bins asbestos era burnt o f f , chare:era
a sb estos p r e sen t, in H rofax r e sid u e s rep resen ts an a a b e s to s is hazard
only.
~Jf
She l i i n i 3 t r y o f Labour ( S a f. 1 . ) la y s down a i i r i t c f 5
u i l l i o n a s b e s to s d u st p a r t i c l e s per- cu b ic f o o t (177 p a r t i c l e s ?Er
o .c .) c f atneaphara. i s is the case with the M in istry 's rsccrrsrd-
stich s fo r silioB ou s d u sts, the value cf th is reoem en d ation is
r e s t r i c t e d by th e l i r i t a d i n f c r r a t i c n upon which i t i s baaed. She
M in is tr y taices no acco u n t cf. v a r ia t io n s in in d iv id u a l s u s c e p t ib
i l i t y , and dcos n o t s p e c i f y th e nathod cf a n a l y s is , c r g iv e any
d e t a il s c f the average d in one io n s c f sn a s b e s to s p a r t i c l e . Ho
dis t in c r ie r is naia bstwaan the various ferns cf a sb e sto s.
' l i t r e s r e c o v e r e d f r e n a s b e s to s b o d ies i n th a lu n g 2 za s b e s to s ia v ie t i n s v a r y in le n g t h f r e n V0$ s in r e n s down to 25 n ic r c n s , and i n th ic k n e s s f r c r 0.2 to 1.0 n ie r n n s . ( H e i. 5 ) I t 2 probable th a t f i b r e s 5 n icro n a lo n g surd a n a ile r s r s ga.E -lih a and z " r 8t a in s d by tha lu n g e .
"23 i n "?* n i 1 XEPSCTS AI7D Pfgcrr/vv'WZM.Tloys
Cfar.Brs! .
'Tha i d e a l , s o l u t i o n i a to r e p l a c e t o x i c n a t a r i a l a , su c h as
J l i s a en d a c b e s to , by r.o n -c o x ic n & t a r i s l a , su ch as d i v i n e and
F Q 3-33-i2303 0359
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..rara, th is course cd a c r i or. has baso fc:T 1 I
lUSCBr Cl
X*
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a o n d -c is -e tin g
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** w.
c c rp o s iric r.
-- _ * . a w h s a l s ; 1 1 P r e d s x p r o d u c t i o n i n Swodsn
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o l i v i n a -> : e a d g
and a a r a l i q u a n tity od d i v i n a
p--c f s r la 'bain s u p p lie d to sene Pos eco o u s t onera in th e u n ite d
Ehs r a p la o e a e n t of b lu e a a b a sto a by a r c s i t s h as baer.
r a s e n d ad by ? e a a o o I n t e r n a t i o n a l L t d . a n d u n d e r ta k e n ,dy an
ir.craas
ru r b a r od Group a o r p a r i a s .
I t sh o u ld , how ever, ba n o ted th a t th a rs is a U n i t to the o c n o e s t r a tio n aver, of nen-toocio d u ste w hich oan be t o l s r a t a d by the l u n g s . Eoe, U in ia t r y o f L a b o u r a e i a i i n i t f o r n e n - t o r i o dus ta cd 50 s i l l io n p a r t i c l e s p e r c u b i d o o t (1 7 6 5 p a r t i c l e s p a r o . o . ) ,
U nfortunately, these rc n -te ric su b stitu ra a are s lro s t in v a r ia b ly co re asp e rs'd va th a n th e u a t e r i h l th e y r a p la a e , w ith thB r a s u lt th a t th s ir u sa nay n o t ba a sound c s s s a r s is ! p ro p o s itio n . U ndsr su ch o irc u n s t a n o a s , s to p s r u s t ba ta k e n tD ra d u s a th e m o u n t nd t o r i o r a t e r i a l e n t e r i n g t h a lu n g s cd p e r s o n s w o rk in g r i c h i t .
E sspir& tcrs era tha le a s t c a c isd a o trry nsthod d er p ro te c t in g , r s r w orking ir. t o r i o d u s t s , Ehe s d f ic ie s o y cd th a c o n v e n tio n a l .j^ d ree nasi: w ith f i l t e r i s q u e s tio n a b le , p a r tic u la r ly whan th e .rash J5E.S u s e d w ith o u t r a d e r a n o a t o s u o h d a r t e r s a s th e d u s t l e v e l end th e p ro b a b le u s e fu l l i d s o f th a f i l t e r . A r a s p i r a to r s u p p lie d d r on an e r o e m s l flcuroa cd o m p r s a a e d a i r , f o r a r s n p l e , th a s h o t - b l a s t e r *3 h a in e r , is s u p e rio r tD th a f i l t e r ty p e . Eow aver, r e s p ir a t o r s are n o t c rd e rta b ie in use and i t is vary d i f f i c u l t to ensure th a t thay are e r r co n tin u o u sly by w orkpeople, p a r tic u la r ly those concerned - - hVe a v y o p e r a t i o n s . E h ey a l s o e d d s r n o p r o t o o r d e r a g a in s t dus t w hich as t i le s in . c lo th in g , and is su b sa q u e n tly shaker, o u r, E hsred o re, ra sp ira to rs should ba rsgurdad s o le ly as a tasp erary saasu re.
Goon n a t u r a l v a n t i l a t i c n
c o n ju n c tio n w ith a high
s r a n d s r d cd. h o u s e - k e e p i n g o f f e r s a r e a s o n a b l e dB grsa cd ra re e r r o r . a g a i n s t i Los. a n d a s b e s t o s d u s t s , a n d i d t h e w o rk in g a p a o a i s
la r g a and open a t th a a id a B , no a n tr a p r o t a c t i c s nay ba n aed ad .
7 and i l a t i o n is a i r o a t i n v a r i a b ly th a o n ly d e m ' cd p r o te c tio n w hich
e r e' c- ~t sK >- a s t e e l w o r k s . A c e m u l a t i o n s cd d u s t r u s t on n o a c c o u n t
be allo w ed to b u ild u p , and i t ' is p ra d e rra d t h a t d u st s h o u ld be
renoved v ia a b u i l t- in vacum . o la a rirg s y s te r, tha cyolczsa or bag-
.te r s cd w hich s h o u ld d is c h a rg a i n t o th a open a i r * 11 a w a y f :
s ry w orking a re a , r a i l i n g suoh a ays ta n , th a dus t e u a t ba dsnpad
non w ith iratar and sh o v e lle d or brushad aw ay. I t ia n av er
s u f f i c i e n t n a r a l y t o d s n p a n c r w o t s i l i c a f l o u r r a s i d u a a a s a. n a a n s
o f r e r e v i r g d u s t, b e c a u s e th e h a z a rd r s a p p o e ra when th a r e s id u a
u rb a n o u r . E h a r s d o r s tt hh ai r e a i d u a a r u s t b e p l a .o a d .i n b i n s r a t h e r
r~
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^`'-e m .u ra ,, i t d o es >n"*oW*t Bfi-i*--4v<e ad e q 'o& ta p r o t e c t i o n a-rs.ir.s-.
oarsa:
o ia ts d w ith croc
iriv
cf rrc:
PcTrerad d u s b -e r tr a o t io r Bystsna aera be rads to c e n tr e !
dust a v e r y a f f e c t i v e l y , and sh ou ld bg c o n sid e r e d s e r i o u s l y f o r any
p a r t ic u l a r ly hazardous o p e r a tio n s auch aa c u t t i n g cr g r in d in g P r e f e r .
On a lu n g s c o a ls , th e se ayataca can prcr/s to bB p r o i i b i t i v s l y
a r p a n siy e , and t h a ir vine in a te e lv c r k s 1 b v i r t u a l l y r u le d out fo r
t ils reuser..
\
\ I n c th s r p o s s i b il i t y a t the atealtrcrk fl end c f th a o p e ra t ic n ia d u st su p p re ssio n a t aouroa. In v e stig a tio n s are a t preaar.t b ein g 'nada i n t o th a p o s s i b i l i t y o f s u p p ly in g P r e f e r b o n d ed v i t h Bodiun. E i l i c a t e ,. an d s t r i k i n g a s u i t a b l a b a l a n c a b a t o a e n s i n t e r in g o f th e b u rn t rssid u e a and th e avoidance c f sla g g in g a t the vcrking fa c a . (E af. 4,)
W hatever p r o te c tiv e n aasu ras are ad o p ted , r a g u la r a i r s a n p l i n g 'a n d d u s t c o u n t s , t o g e t h e r u rith p e r i o d i c n e d i o e l a s a n ir s t- * ion s i a l l p a rs e m e l lik e l y to ccra in to re g u la r o c n ta c t ric h tonic d u sts, nay baoone n so aa atry .
Mp.rrT!i*si*.qrTr.ura : H ix in x r -gt&jra
S i l i c a du3t m y re a c h a dangaro.ua e e n c e r t r u t i s r in th e
s tn c s p h e r a v h an s i l i c a f l o u r i s ch a rg e d i n t o th a h y c r o p u lp s r , and. f c r a s h o r t irh i l e a f t s r v r a r d s . ffiie P r e f e r H a e m a l (V c lu a e 5 , J-cbbco
handbook e f n'erks O c n tro l) rs c c m a n d s c h a rg in g th a s i l i c a in i t s p a p e r s a c k , and t h i s p ro c e d u re ah s u ld be a llo w e d w h e rev er p o a s ib ls f i l i n g t h i s , v e n t i l a t i o n c f th a s i r i n g p l a t f c r u s h b e * c --r--o v e :
to th e g r s a te e t p o s s ib le deg ree.
;t is at thi!
caw b l u e an b e 8to s i a h a n d le d .
tincar n c rn a l e sn d itio n s cf w eighing and r i r i n g , the u n h u rt cf
asb e sto s d u st produced. ia v ary s n a il because th a fib ra s appear t:
ba s e n a w h a t " a r p o n a d " . E cw aver, w h a te v e r d u s t i s p ro d u c e d i s
h ig h ly t o r i s , and tho s a f e s t ocuraa is o b v io u sly to ra p i a s blue
nsbastoB by w h ite a s b e s to s in p u rsu an ce cf c u r r a n t ra o : laad & l
Pcsaco In te rn a tio n a l L td.
r r o f s r Hs.r.uf a c t u r s 1 H c u l d i n r bts-s-a .
ia p o ssib le th a t th s r i s t d sv elcp sd du rin g the da-
ra te r
fnlt"zxL--^a c f r z z z i m ,.* -r a e r a r a , due 00 e s c a p a o f p r a s a u r e
bsrreen ha tore h a lv a s c f an i l l - f i t t i n g c r d i r t y t o o l , ea-usea
a ra o s p h e : i o c o n tE n in E - tio n . Ho a c t u a l n e & s u r e r a r t a a r a a v a i l a b l e ,
o n tin u a c.
?O S --Q 3-0G a3Z
0361
b u t i t i s re a s o n a b le to assume th a t th e w ater d ro p le ts in such a
*.
s la t are capable of carrying s ilic a p a rtic le s w ithin the resp irab le
p a r tic le s iz e ra n g e . Steps should be taken to e lim in a te the cause
of s p ra y in g ., V a ilin g th is , n ist3 ao formed should be q u ick ly
d is p e rs e d and removed by v e n tila tio n .
Uhe c l o t h i n g o f th e m achine o p e r a to rs n ay become h e a v ily
S a ile d w ith s l u r r y , e t c . , and a h a z a rd o x ia t3 when su c h d e p o s its
dry, p a r tic u la r ly i f the c lo th in g is shaken out. O perators should
avoid s o ilin g th e ir o v eralls, and operations tending to brin g th e ir
c lo th in g i n t o c o n ta c t w ith wet P ro fa x , f o r example le a n in g acrcas
p a r ts of th e m achinery which n o rm ally become w etted by s l u r r y o r \
sp ray , s h o u ld be e lim in a te d . R eg u lar changes of o v e r a lls sh o u ld be
p ro v id e d .
.
y
Pr o f am M a n u f a c tu r e : F in is h in g S ta g e .
Ib o lo n g - te r m a in m ust ba to produce P ro f am p ie c e s o f the co rrect: s iz e and shape fo r the cu sto m er's moulds, w ith o u t recourse to c u ttin g and g rin d in g oversize or badly formed Pref&x to th e required shape.
Where c u ttin g , g rin d in g , f i l i n g or l i n i a h i n g bocome n ec essary in Preface m anufacture, atm ospheric co ntam ination by s i l i c a and asb e sto s can a tta in dangerous le v e ls . Blue asb e sto s, i f u s e d , w i l l now ba i n a d ry , d u s ty s t a t e , , and w i l l c o n s e q u e n tly bs very dangerous, even in a sin g le exposure. th ere fo re , strin g e n t
p re c a u tio n s m ust be taken; thaae in clu d e d u st e x tra c tio n from th e im m ediate p o in t whore d u st i s g en e rated , and i f e x tra c tio n i s not 100^6 e f f i c i e n t th e o p e r a to r s m ust be p ro v id e d w ith r a s p i r a t o r s , p re fe ra b ly o f a ty p e w ith an e x te rn a l a i r supply i f th is. car. be so arran g ed th a t i t doea n o t unduly hamper th e ir movements. Iz must be em phasised a g a in a t th is p o in t th a t where blue a sb e sto s i s s t i l l u sed , i t m ust be elim in ated as soon as p o ssib le in fav o u r of am osite.
P r o f a x i n t h e Custome r 's Works
Thar i a n o doubt t h a t i n t h e p r e s e n t f o r a o f P ro fa x we are su p p ly in g a product which, under unfavourable circum stances, can giv r i s e to to x ic le v e ls of atm o sp h eric c o n ta m in a tio n by s i l i c a an d a s b e s t o s . Tho fo rm e r p r i n c i p a l r i s k a s s o c i a t e d w ith P ro fax , th a t of cancer re s u ltin g from in h a la tio n of b lu a asb esto s, p ro b ab ly w ould n o t nave e x iste d in th e custom er's works owing to tha. f a c t t h a t th e carcin o g en s p re s e n t i n th e a sb e sto s would have bean b u rn t o f f d u rin g the i g n itio n of th P ro fa x . The l a t e r e r o c id o lita - f r e fo rm u latio n s do n o t o f f e r a c&near h a z a rd .
I t has alre ad y been s ta te d th a t good n a tu ra l v e n tila tio n ,
to g e th e r w ith good house-keeping, o ff e r a reaaonabl degree of p ro te c tio n a g a in s t s i l ic o s is and a s b a s to s is h az ard s. The co at of
-.continued r
0362
- 12 -
a lr o o t always the sil A tta r iio n i s drawn (See page. ? )
on s y a t ens rends r s
in pr3.Ct i c a b le on &
th a r a a yT,
--V., -
v --o.
t u r 3.1 ve r t ii& ><c r 12
f c m c f r*t a c t i cr. e r i s t i r -i a Btii1Wf.r V5
;hs r a c e i..i.*GwCSi y,3 f o r <I'w5 " r cn sv a b e v a .
nsoasaary.
.0 n a t a r i a l a a r s i n u s e . r e g u l n r a s a n p l i r . o ka u p c r. ?e r s c m .e l l i k e l y to be a rrc j e t e d na;V 5 9
a x p e r i r a n t :s 0endu cise. i t ? oa ac 0 I n t a r n a t i c ; 1 l b . (454 S = -) of P rof,zx as con ta:insd a
t o t a l o O.142 ga*. o f r a s p im b l s a t t a r , of which O.Op3 g s. was
a s b e s t o s . To co n v e r t th e se w aights in to a o t u s l nunbers of p a r t i le s , &a a r b itr a r y aaaunption B u st f i r s t be Bade of the average dimensions
o f tha p & rtiolaa . Assuming th a t the a sb estos p a r ti la s average 50. rioror.o in le n g t h r 1 c ic r o n in d ia n a ta r , t h is means th a t 1 lb . c f
Trofeo: con g iv e r i s e to 755 B i l l i o n p a r t ic le s of a s b e s t o s . To a c h ie v e tha M in is tr y of L abour1a l i m i t c e n o sn tr a tio n c f 5 n i l l i c n
p a r ti le s per cubic fo o t of a ir , 151*2 cubic fe a t of atrosphara r i l l be r e q u ire d f o r the sa fa d is p e r s a l of the asb estos in 1 lb . of Profor
t s h . i fu r th e r 189 oubio f a s t r i l l be r e q u ired f e r tha dispara ai o f th e s i l i o a p a r t id a s ,- a s s u r in g th a t th asa are sp h e r e s w ith an
average .f a n s t e r c f 5 r ic r o n s , and th a t.t h a ash o c n ta in s 95? e r y f i t s l l i n s s i l i c a , g iv in g a t o t a l acresphera raquircn or.t c f 50
cusi fe e t per l b c f Prefer ash.
Sy aaicing sene fu r th e r assumptions i t is p o ssib le to cake a rough a stin a te cf the voluns of a ir roquired for the safe disper s a l o f th e ash o f a P r a fsr a o s o n b ly . S o t a l l tha a sh f r e r a Preface as aa n c ly i s d is p e r s e d i n t o tha a i r , as a g e n e r a l r u le about two
t h ir d s r a m i n u n d isp e r se d , Jlb an a r s r p ls , an M.104 as s o r e ly nay be o m s ia e r a d . T his woighs 4-4 l b . , about 3Of of which i s ash . ? r = s tr
in g th a t cna th ir d of th is ash i s d isp ersed in to tha a ir the to ta l r e s p ir a b le n a t t a r gen erated by tha s t r ip p in g c f an M.IOd a ssen b ly
w i l l n a sd 4490 oubio ai o f a i r f o r d is p e r s a l. T his v ciu n e car. be
V is u a lis e d aa a cube c f r a th e r l o s s than 16. $ f t . s i d e , which should be e a s il y a tta in ed in u o st steelw o rk s. However, c a lc u la t io n s o f t h is s o r t car. e r ly ba apprerrirate and are n o t n e c e s s a r ily very c o r v ir r ir g to o u stca a r s. They ara no su b s titu te fo r proper
dust sam pling carried ou t1a t a le v e l of 5 to 6 f t . above the f le e r .
Tha typ e c f c a lc u l a t io n l a i d cu t s ie v e w i l l probably ba regarded by era to n e r s as b ein g aaonwhat academ ic in n a tu re, and i t w ill baccne in c r e a s in g ly d i f f i c u l t as t in s goes by to oorvinoe than th a t tha hazard in v o lv e d i n u s in g P r e fe r *,0 i s c f a v e r y low erd ar. The cnly lo n g -ta r n so lu tio n l i k e l y to prove s a tis fa c to r y is to supply a Profsn rarufs-coured f r s s n on -ton ic n a tsr ia ls .
- continued -
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APPHTDIa g ~ i a s i~ b ls Ccr e r . -era t i e r s o f M i r s r a l S '.'qTK
At r 0B cr.gr a *
Suba tarsos
Silica Quarts C ristobalite
liillio r .3 of Per t i d e s Par Cubic Toot cf Air
2 60 ^sio2 + 5
cLd.'S'-o
P a r t i la s par Cubio C erticstra
\ ....... 8 3 2 5 .
f> S i0 2 t p
d itto
S ilicatos
A sb estos
5
Jiiea, Bo&pstrae, Talo
20
Portland Cacart
50
177 70= .1,766
I r a r t ("'fTtisaace"^ Busts
rarp ics ; A lucina, c a lc ita , dolom ita, lia s s i c a s , s a r c i a , s i l l s cu oarsid a .
50 cr 15
par cubic rstrs, Thai.ever is the e r a llc r -
1,76=
A dapted fr e n X e ierso cs 1.
pQ S--0 E--0 O3 3
0366