Document pLeB6dog3DJL1gK3kOnY1G5X

lo Submitted to: BIOSEARCH. INC. tp.eo.lbeoxph85o98neph:ilade(lp2hi1a5. )penns8yl4v8an-ia441991091 Project Number -78-1433A 33H CCoenmtpearny St. Paul, Minnesota 55101 Material: sample Received: Date of Report: Test: Object of Test: Procedure: 3M Company - T-2297C0C 9/14/78 Study Initiated: 9/21/78 Study Completed: 10/13/78 10/19/78 Acute Oral Toxicity = Rats Ttohestsuudbyjectthemaatceurtiealo.ral toxicity in rats of TSuhoermgaronu-pWsistoafrteSntra(i5nmwaeliegh5in5gfebmeatlwee)enal2b0i0no rats of the arnadts30w0eregndweeprreiveedmploofyefdoodinbutthisnotstuwdayt.er Tfhoer a2n4dhdoousrsedprbiyordirteoctdosaidnmgi.nistEraacthioannimoafl twhaesewxepiegrihmeedntal maantderdioaslingintnoeedtlhee. stomach by means of a syringe The sample was dosed as a 50% w/v suspension in water. The following dosage levels were administered: 01..055 gng/nk/gk.g. Results: Conclusion: Ffoooldlowaindngwaadtmeirniasdtr1aitbiiotnunthfeorantihmeal1s4 dwaeyreobaslelrovwaedtion pfeorriosdigndsuroifngtwohxiicchitytimaendtmheortraaltistiweesr.e observed See Table 1. aThlebinsoubjreactts mhaatserainalacwuhteenorsatludiLeDdSO ignremaatleerantdhanfemale 0.05 gn/kg. but less than 1.5 g/kg. Karl L. Gabriel, Director V.H.0.,0P6h.1D7. 83 oe 1 Acute Oral Toxicity Material: 3H Company = T-229766C, 5 a 50% w/v suspension in water. Concentration: 500 m/l - DLeovseal"ge NofnbAenrimals sky dosed HortaBtayist.ies 12345678510 DTeoatdal TSoutravlived WIeniigthiatl VFeilnaglht 12131 Wows bays om = 0.05 sees 6000000000 0 0 0 0 o 5 as 255 0.05 Sfemles 00000000000000 5 0 2%0 15 sales ERERIE 5 25 - 15 sfemles 1101001 =-0=1= 5 210 - The L05o is greater than 0.05 gn/ks. but less than 1.5 g/kg. dM1oe75pruegnsatso/wekadyrdotrhessyananpnitimo-anclsosmwteworesereeobdbyeseprr2ve4esdsheoduortsa.fttheerThdeo2s-3aagnehiomuoarflss0.ar0ne5dmasginuee/vdke.retlhiysAt vSoayniunnatt]iondeartehvsealoecdcunrroetdhinogverresseavrekraalle.days. Gross pathologic 238 3@4