Document pB5wj7zwwJv8gqrK4gGkegm0k

Applied Epidemiology, Inc. baseline study results and Wong et al., 1992 results: Observed (Obs) and expected (Exp) deaths, standardized mortality ratios (SMR's) and ninety-five percent confidence intervals (95% CFs) using U.S. white male mortality rates, plant state-specific white male mortality rates, for follow-up through December 31, 1982 Cause of death All causes Obs 1569 Applied Epidemiology, Inc. baseline analysis U.S. reference rates State reference rates Exp SMR 95% Cl Exp SMR 95% Cl 1734.92 90 86-95 1876.87 84 80-88 Obs 1536 Wong et al., 1992 U.S. reference rates Exp 1705.27 SMR 90 95% Cl 86-95 All malignant neoplasms Cancer of: Buccal cavity & pharynx Tongue Other parts buccal cavity Pharynx Digestive organs & peritoneum Esophagus Stomach Intestine, except rectum Rectum Liver & biliary tract Pancreas 389 363.09 107 97-118 380.46 102 92-113 359 341.73 105 94-17 13 11.81 110 59-188 11.61 112 60-192 12 4 2.74 146 40-374 2.56 156 43-400 4 3 3.15 95 20-278 2.98 101 21-294 3 5 5.66 88 29-206 5.79 86 28-202 4 106 94.82 112 92-135 91.43 116 95-140 99 7 8.59 81 33-168 8.37 84 34-172 7 11 16.10 68 34-122 14.78 74 37-133 10 21 31.44 67 41-102 29.57 71 44-109 20 5 9.71 51 17-120 8.89 56 18-131 5 39 8.11 481 342-657 9.11 428 304-585 37 18 19.21 94 55-148 18.89 95 56-151 16 11.55 nr nr nr 89.21 8.07 16.01 28.79 9.91 5.77 18.40 104 54-181 Ill 90-135 87 35-179 63 30-115 70 42-107 50 16-118 641 450-884 87 50-141 C M A 171082 Page i of6 Applied Epidemiology, Inc. baseline analysis Wong et al., 1992 U.S. reference rates State reference rates U.S. reference rates Cause of death Obs Exp SMR 95% Cl Exp SMR 95% Cl Obs Exp SMR 95% Cl Peritoneum & other digestive organs 5 1.65 302 98-706 1.82 274 89-640 4 nr - Respiratory system 128 132.71 96 80-115 151.35 85 71-101 115 122.25 94 78-113 Larynx 3 5.44 55 11-161 5.94 50 10-148 3 5.24 57 12-168 Trachea, bronchus & lung 122 125.56 97 81-116 143.58 85 71-101 111 115.87 96 79-116 Other respiratory system 3 1.71 176 36-513 1.83 164 34-480 1 nr -- Prostate Kidney 15 16.55 91 51-149 15.59 96 54-159 `5 15.20 99 55-163 11 9.53 115 58-207 9.73 113 56-202 1! 9.06 121 61-217 Bladder 6 8.58 70 26-152 8.34 72 26-157 5 8.46 59 19-138 Skin 7 8.28 85 34-174 8.34 83 33-171 6 7.36 82 30-178 Eye 2 0.32 628 76-2269 0.42 475 58-1717 0 0.31 0 Brain & other nervous system 22 13.61 162 101-245 13.05 169 106-255 23 12.76 180 114-271 Thyroid 2 0.74 269 33-972 0.73 274 33-989 2 0.68 293 36-1059 Bone 2 1.66 120 15-434 2.19 91 I1-330 2 1.81 111 13-399 Connective & soft tissue 7 1.84 381 153-785 1.91 367 147-755 6 nr - Lymphatic & hematopoietic 37 36.91 100 71-138 37.29 99 70-137 37 36.28 102 72-141 Lymphosarcoma/reticulosarcoma 10 7.77 129 62-237 7.72 130 62-238 11 7.98 138 69-247 Hodgkin's disease 3 5.16 58 12-170 5.31 57 12-165 3 5.45 55 11-161 l eukemia & aleukemia 12 14.73 81 42-142 15.03 80 41-139 13 13.94 93 50-159 C M A 171083 Page 2 of6 Cause of death Other lymphatic & hematopoietic Unspecified Benign St unspecified nature neoplasms Unspecified nature of eye, brain & other nervous system Other Obs 12 29 7 4 3 Applied Epidemiology, Inc. baseline analysis Wong et al., 1992 U.S. reference rates State reference rates U.S. reference rates Exp SMR 95% Cl Exp SMR 95% Cl Obs Exp SMR 95% Cl 9.25 130 67-227 9.23 130 67-227 10 8.37 119 57-220 22.37 130 87-186 25.13 115 77-166 23 nr - 5.70 123 49-253 5.54 126 51-260 4 5.08 79 21-201 2.68 149 41-382 2.80 143 39-365 1 nr -- 2.07 145 30-424 2.01 149 31-436 3 nr -- Diabetes mellitus 23 23.89 96 61-144 25.38 91 57-136 22 23.52 94 59-142 Diseases of the blood & blood forming 2 4.17 48 6-173 4.37 46 6-165 2 3.76 53 6-192 organs Mental, psychoneurotic St personality disorders Alcoholism Other mental disorders 7 12.74 55 22-113 13.15 53 21-110 4 11.80 34 9-87 4 8.86 45 12-116 9.20 43 12-111 3 nr - 3 3.87 77 16-226 3.94 76 16-222 1 nr C M A 171084 Page 3 of6 Cause of death Diseases of the nervous system & sense organs Multiple sclerosis Other diseases of nervous system & sense organs Obs 14 3 It Applied Epidemiology, Inc. baseline analysis | U.S. reference rates State reference rates I Exp SMR 95% Cl Exp SMR 95% Cl Obs 17.29 81 44-136 17.40 80 44-135 15 Wong et al., 1992 U.S. reference rates Exp SMR 95% Cl nr -- 2.31 130 27-380 1.87 161 33-470 3 nr - 14.98 73 37-131 15.53 71 35-127 12 nr -- Diseases of the heart Rheumatic heart disease Ischemic heart disease Chronic disease of endocardium Other myocardial degeneration Hypertension with heart disease Other heart diseases 642 680.17 94 87-102 735.95 87 81-94 601 nr -- 12 18.71 64 33-112 16.46 73 38-127 14 19.33 72 40-122 535 583.71 92 84-100 630.80 85 78-92 488 597.73 82 75-89 5 3.55 141 46-329 3.17 158 51-368 3 nr - 3 7.89 38 8-111 5.84 51 11-150 31 nr - 23 15.20 151 96-227 14.50 159 101-238 23 nr - 64 51.12 125 96-160 65.17 98 76-125 42 nr -- Other diseases of the circulatory system 109 129.73 84 69-101 143.51 76 62-92 103 nr -- 1 lypertension without heart disease 3 4.53 66 14-193 5.06 59 12-173 8 nr - Cerebrovascular disease 78 86.64 90 71-112 96.46 81 64-101 70 91.93 76 60-96 Diseases of arteries, veins & pulmonary circulation 28 38.55 73 48-105 41.99 67 44-96 25 nr - Page 4 of6 C M A 171085 Cause of death Diseases of the respiratory system Pneumonia Chronic & unspecified bronchitis Emphysema* Asthma Pneumoconioses & other respiratory diseases (includes COPD) Emphysema & COPD * Diseases of the digestive system Diseases of stomach & duodenum Hernia & intestinal obstruction Cirrhosis of the liver Other digestive system diseases Obs 70 16 2 17 l 33 63 9 2 38 14 Applied Epidemiology, Inc. baseline analysis Wongetal., 1992 U.S. reference rates State reference rates U.S. reference rates Exp SMR 95% Cl Exp SMR 95% Cl Obs Exp SMR 95% Cl 91.93 76 59-96 111.60 63 49-79 70 87.61 80 62-101 31.54 51 29-82 34.41 47 27-76 15 31.94 47 26-78 4.38 46 6-165 5.44 37 4-133 2 nr ~ 20.12 84 49-135 23.45 72 42-116 17 nr -- 3.00 33 1-185 3.76 27 1-148 I 2.89 35 1-192 30.30 109 75-153 41.21 80 55-112 35 nr - 41 22.83 180 129-244 97.55 65 50-83 93.36 67 52-86 60 95.58 63 48-81 12.11 74 34-141 12.02 75 34-142 8 11.15 72 31-414 3.81 53 6-190 3.83 52 6-189 2 nr -- 56.70 67 47-92 50.91 75 53-102 35 56.06 62 43-87 24.93 56 31-94 26.60 53 29-88 14 nr -- Diseases of the genitourinary system Chronic/unspecified nephritis Other genitourinaiy diseases 8 4 3 19.80 40 17-80 21.55 37 16-73 9 9.41 43 12-109 10.11 40 11-101 4 3.77 79 16-232 4.33 69 14-203 20.41 44 20-84 8.29 48 13-123 nr "" C M A 171086 Page 5 of6 Cause of death Diseases of musculoskeletal system & connective tissue Obs 1 Applied Epidemiology, Inc. baseline analysis H U.S. reference rates State reference rates 1 Exp SMR 95% Cl Exp SMR 95% Cl Obs 3.15 32 1-177 3.28 30 1-170 Wong et al., 1992 U.S. reference rates Exp SMR 95% Cl - Symptoms & ill-defined conditions 7 21.51 33 13-67 26.68 26 11-54 10 21.79 46 22-84 All external causes Accidents Violence Suicide Homicide Other causes 183 226.58 117 153.26 66 73.32 49 53.89 17 19.43 15 25.00 81 76 90 91 87 60 69-93 63-91 70-114 67-120 51-140 34-99 256.67 175.92 81.75 55.51 26.24 25.49 71 67 81 88 65 59 61-82 55-80 62-103 65-117 38-104 33-97 168 225.97 108 150.16 60 nr 46 52.78 14 nr ? nr 74 72 87 - 64-87 59-87 64-116 Unknown 28 97 nr=no rates available for category of death * In the NIOSH categories of death (used in AEI baseline analysis), deaths from emphysema (ICD-7 527.1; ICD8 492; 1CD9 492) are included in Emphysema and deaths from COPD (ICD-7 527.2; ICD-8 519.2; ICD-9 496) are included in Pneumoconioses & other respiratory diseases. In the Monson categories of death (used in Wong et al. analysis), Emphysema & COPD includes deaths from any of the following: Pulmonary collapse (ICD-7 527.0); Emphysema without mention of bronchitis (ICD-7 527.1); Other diseases of the lung (includes COPD) (ICD-7 527.2). C M A 171087 Page 6 of6