Document pB3eBmjpxg96EkO06qN9wzeZj
BIOSEARCH. INC. Tpoe.lbeopxh8o59n8ep:hilede(lp2hi1e5. )penns8yl4v8an-ia441991091
Submitted to:
33MH CCoemnptaenry
:
sSts.iolPaul, Mimesota
saterial: Sample Received: tate of Reporc: Test: Object of Test: Hethod of Test:
Results:
31 Company - T-1585 August 25, 1976 Septenber 16, `1976 Primary Eye Irritation Study = Rabbits wThoicdhetetrheminseubjtehcetdmeagtreereiaolf miaryriptraotidounc,e wihfenany, TThnissciltieesdt wianstopetrhefoerymeesd oifn oalrbdienrotoracbbliatsss.ify SthuibsstamantceersiLaalbeulndienrg Atchte. Federal Hazardous aThned mienthtohdesgermapdlinogyedofinthethetesttestmiantge,riaelvalaureatitohnose adnedscArritbiecdleisn, SAedcntiinonist1r5a0t0i.o4n2 a-ndHazEanrfdoorucsemeSnutbstances 7R.e7g2u7l0a1t9i,ons2,7 SFeepderraanlperReg1i9s73t.er, Vol. 38, No. 187, The sample was used as supplied.
Siinxthhiesaltshtyudyy.oung0.1aduglntofalbtihenoexrpaebrbiimtesntvaelremautseerdial awansimailnsstwihlilleed tihnetootthheerreiyghets eryeemsaionfedthuentrteeastted to SFerrovmethase ecyoenst.rols. The test material was not washed
5Th6e 7trdeaaytesd efyoelslowweirneg eixnasmtiinleldatiaton1,of24t,he48tes6t72 hrs. & mTaetseurlitasl waisntmoadtehe ineyeasc.cordIanntceerpwrietthatitohen gofradtiheng SGyrsatdeimngouEtyleinIerdritiantitohen B"yIlHlauzsatrrdaotuesd SGuuibdsetanfcoers".
TThaebleresuwlhtischofcovtehresteeascths aorfetshehowannimianlsthetraecactoemdpawniything the test material.
00111
3M Company - T-1585, Primary Eye Irritation Study.
SCmosnlculursiioonn:s
JJBeaeesnteidnmoatntehretihaedleafciicsnoiamtpioapnnryiimoanfrgyhteoatbAultleta,rrtehTreereisnsucabn-et: aSetcitoionnar1y500T.a4b2a i(nbg) w(i1)th (2r)espP.ect2 Go7013 thaantd sreecqtuiiorne:s
DKairrlectL.orGabriel, V.H.D., Ph.D.
000112
TABLE 1 Grades for Ocular Lesions
Material: 3K Company - T-1585, as supplied.
Rabbit No.
Cornea Upacity Ares
Iris
1 2 hour i3 65
4
2
uo
u
2
&&
&&
22
&I
iu
2 2
1 2 24 hours 3i 65
4
uo 4
2 2
0&
o
22
4
"u
22
1 2 48 hours 3I 65
&&
22
&
22
u&
I4
2 2
21 72 hours 3
Lk 56s
IIll
4o
2 2
4
I
2
u &
I I
2 2
u
2
21 5days 3u
56
4 &
4 "
2 2
44
4"
22
I4
4
22
1 2 7 days 3I 65
&
& L
2 2
44
4I
22
44"
iI
2 2
Conjunctivae Redness ChemosTs
2
0
2
hl
2 2
o &
2 2
4 u
22
ui
22
I&
22
II
22
u"
22
44
2 2
4 4
2 2
4 &
2
4
2 2
& &
2
&
2
uo
2
u
22
uIo
22
4i
22
4o
22
4
2 2
o 4
Discharge 3 3 3 33 3 33 33 33 33 33 3 3 3 33 3 3 3 3 3 33 33 33 3 3 3 3
001173