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Library of Congress Cataloging-in-Publication Data Neoplastic diseases of the blood / edited by Peter H. Wiernik ... [et al.1-2nd ed. p. cm Includes bibliographical references and index. ISBN 0-443-08693-1 1. Leukemia. 2. Multiple myeloma. 3. Lymphomas. I. Wiernik, Peter H. [DNLM: 1. Leukemia. 2. Lymphoma. 3. Multiple Myeloma. WH 250 N4 381 RC643.N46 1991 616.99'419-dc20 DNLM/DLC for Library of Congress 91-194 CIP Second Edition 0 Churchill Livingstone Inc. 1991 First Edition 0 Churchill Livingstone Inc. 1985 All rights reserved. N o part of this publication may be reproduced, stored in a retrieval system, o r transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without prior permission of the publisher (Churchill Livingstone Inc., 1560 Broadway, New York, NY 10036). Distributed in the United Kingdom by Churchill Livingstone, Robert Stevenson House, 1-3 Baxter's Place, Leith Walk, Edinburgh EH1 3AF, and by associated companies, branches, and representatives throughout the world. Accurate indications, adverse reactions, and dosage schedules for drugs are provided in this book, but it is possible that they may change. The reader is urged to review the package information data of the manufacturers of the medications mentioned. The Publishers have made every effort to trace the copyright holders for borrowed material. If they have inadvertently overlooked any, they will be pleased to make the necessary arrangements at the first opportunit?-. Acquisitions Editor: Beth Kaufinaii Barn. Copy Editor: Bridgett Dickimon Production Designer: Angela Cii-riigliaro Production Supervisor: Shal-oit Tilder. Printed in the United States of America m/(&q<+,c E~ f W H a ; ),, cl.`, . Nupg!$@;> First Dublished in 1991 7 6 5 4 3 2 I 2 eB E E 8 'WW e EW % L F '1HN %OL 0 6 08 OL 0 9 OS 09 OE 01 06 08 OL 09 OS OP OE OZ rt -----r 1 "O aJ 1 3t65-5561 V9-0961 69-S961 4Pf-Of61 6f-Sf61 - d2te-OBSI - ~ - r tS-Of61 6s-SS61 t9-0961 69-S96L 9f-OL6I 6L-Sf6L 98-0861 001 m 6 0 0 0 0 aJ v) 0 Z I 001 > aJ v) S a lHMN0N SlllHM 1- sa(ewaj S3XInSOdX3 N O I L V I a V ~ SZI?InSOdXZI 1 V N O I L V d n 3 3 0 a N V 7VLNZII"OtIIANB N OV ,"',LL c = 9 a a 3 3 3 J3 > P t ' I = XO H .I3 a a r J3 3 V J3 ~ 0 1 1 L I O 3a s n 3 1 fE1 = 8NS 13 t'l = 88 E) 9 E) H ,L'l = XG a J3 9 V J3 13 .I3 J3 .I3 13 13 .I 1 .I1 _1I _1I J? I) '3 H 3 9 9 t.' 8 .I 3 6'1 = HH v H H 9 rl 9 H NOI~v?nI,,uIJ,s 3IN33ILNV 3INOHH3 do TIOX SNOISflT3N03 i1 I1 II 11 I :I 1 -1 I iii 01 I '8tZ 'LPZ '9PZ 'Et.? 'tPZ 'EPZ 'ZPZ 'ItiZ 'OtZ '6fZ '8fZ 'if? 9fZ 'CfT 'tfZ 'ffZ 'ZEZ