Document omON1OBvjnGrX1wrOVO0Vdgy3

Oohehe? 4, .1967 Dr. Bruce f. ftaltfe, Medle&l Director Chevrolet Sivi&ica Senerst Meters Corporation. Hastens, Stmt fork 13&62 Bear 8r, Saltfes Mr. PPed Cnims* of your plant u&s in St* Beale last Friday. Baring visit to filler r. Wheeler, our industry hygienist had the pleasure of aeefcing Mr* Colsair and diseunaing with mug our viei*s of t&a safe handling end use of Pydraui A-200, tmm of BSoosaftto's fire~reslateat hydraulie fluids , tshish X understand is used in your pl&nt-~*s well as In ether tteacnl Katar* installations. Mr. Wheeler has suggested that X oeafiim Mi# verbal discussion for your convenience. Aaiaal toxicity studies with ?ydrawl A~200 have indicated that the oral lethal dose (I^q) to rets la 13,509 l1. tigress per kilegre. The lethal does whea the as tori* l t&s applied undiluted to the mferekea skin of relit-its it approxlsakeiy 1250 milligram* per fciiagmau V eedeXade fresa the above that accidental lageatioa on the pert f haasene ie net a partismiar hazard in view of the high orei lethal dot# in rets* Sisdlarly, single Baselv# skin expowfiroa should not he isaaediately hazardous* The lethal dose ottaiaad in skin penetration studies is &sch, hewever, that prolonged and repeated skin contact should he avoided based*# of peasill# ay*teale effects* la addition, pro lagged end riposted s in oontaot my lead to skin irritation, We s^ao feel that vapor inhalation should he avoided often the fini^i is heated to elevated temperatures* Sunk exposure again relalist to prolonged or repeated exposure* rather than abort* teraj naaaive oar seat* exposures. Sene peer# age* * ohtalaed aout/c toxltUjr data for anise is eapsaed to amosive aeaetntr&tloas of Khemalljr dec ospused Pydraul A~290. A copy of the remit* of t)hee brief experlaeats la enclosed. (Please note that the / \1 ' ! ' DSW 586230 STLCOPCB4091564 ftr. Bruce 7* 3ith October 4, 1967 sample tested was identified as *08-95*. This wee the Development: designation af the fluid prior to the adoption f the trade-name, *fydraisi A-200"). I think you will agree that the oanditions of the test were extreme in that husaaas would net voluntarily raueiA la atmospheres to grossly contaminated. In the aeries of experiments, ell enisle survived after signs and syuptees vhlet* were principal ly related to the Inhalation of the Sl which is feraed by the thereat deaosmoaiUon. the us* of fydrauX A-BOO In industrial hydraulic fluid appli cations should set present toxicity hazard* during the trans fer of the fluid frsss original containers to the hydrsuHc system* Obviously when the fluid is within the hydraulic eye toss, there should be a exposure and uotteequeatly, ao tesavA* in the event of rupture of hydraulic line* usd subsequent splashing or spraying of the fluid on the heated surfaces, vspsra of the fluid and possible daeaapoaltloft predasta (depending on the temperature of the heated surface) uy be irritating If inhaled to the degree that worker win set voluntarily expose bbefiselvea to toxic oeaaeatrafcioas. So harardews exposure should result during the Interval required to shut down the system end obtain suitable respiratory protective devises during repairs t# the system. Me would mt anticipate any greater hazards dseriag rout in* s&inteaiuiee of a ays tea containing Pydraal A-200 then would be present if the imates obtained aj*hssphebe base fluid. ; Xt weald appear to be good practice to vip* dry eny eqalpisent feefSre doing any welding on surfaces which sight be "wetted"5 vijm or have a fibs of either type fluid on the. X asm be of let ue knew, farther assistance, please do not hesitate Very truly yours, S. test Kelly, S*B. Hedlael Director WSte^ayfe-Paj cot md Cslsar Sw fork Jfcefc BsmaregUe Sew fora Q, B. Orahasa - Mew York ttatmn Y Jefcoaaa bees Dale Smith DSW586231 atbcjLsJ: <5>Ay</ */,. y-sZ-Vc STLCOPCB4091565