Document oeZQpjeZjqGrOVD6N5xVxdE43

CHEMICAL PORPHYRIA IN MAN The diagnosis and occurrence of chronic hepatic porphyria in man caused by halogenated aromatics (polybrominated biphenyls, polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin) Porphyrinogenic action of halogenated aromatics in experimental animals Edited by J.J.T.W.A. STRIK and J.H. KOEMAN Department of Toxicology Agricultural University of Wageningen 1979 ELSEVIER/NORTH-HOLLAND BIOMEDICAL PRESS AMSTERDAM NEW YORK OXFORD R&S 024707 1979 Elsevier/North-Holland Biomedical Press All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of the copyright owner. ISBN; 0-444-90159-6 Published by; Elsevier/North-Holland Biomedical Press 335 Jan van Galenstraat, P.O. Box 211 Amsterdam, The Netherlands Sole distributors for the USA and Canada; Elsevier North Holland Inc. 52 Vanderbilt Avenue New York, N.Y. 10017 Library of Congress Cataloging in Publication Data Main entry under title: Chemical porphyria in man. Bibliography: p. 1. Porphyria, 2, Ealocarbona--Toxicology, 3- Aromatic compounds--Toxicology. 1*. Liver--Diseases. X. Strik, J. J* T. V, A. II. Koeman, J. H. fic632.P6cl7 6l6.3'99 79-19136 ism 0-111-50159-6 Printed in The Netherlands i I File-- TieK. X R&S 024708 K-aasi- tiffv) X Dfl- ru_t3- Still ....... y -_P&zJ7iM- 3U f)H-t>a4a--isS? .... K-/t>3ln -A , K-P1?6 K-U.3SB Mr M. K-lSgB.X .....X _ _ _Dc--ei44-7:?53 K-.3fet4i ^-KrJLi33V_ Hf----------------------------------- K-^aaR _PR-ouf- feast X K-iaji -J(__________ -D.R--P.14& - 24/^ K- _atj?o3i- fri-M ^JSD'BOO K'-fatt, rt-3?Pg4________________ DH-0H8- U*L K-ioa oin M- US35 X X K-SfeAsc.- ^__________ -PR- PJAS^SS X ~K- M'll.t K- i >31 _K~5u43 -- X K-4o<ica ________________________ --X________________________ K-3C,3lt_______________ K- 3T-1SS __K- tltil . --X______________________ Acetamide (SO-35-5) N-Acctoxy-NdJ-QuorenyltceUmide (6098-44-8) f N-AcO-2-FAAl 1'-AerOimxfrole (34627-78-6) Acridine orange (65-61-2) fAOl Aflatoxin B. (1162-65-8) fAFB,l Aflatoxin B, (7220-81-7) [AFST] 4-Aminoixobenzene (6U-U9-3) 4-Aminobiphenyl (92-67-1) 3-Amido 1 2 4-triar/le (61-82-5) Aniline (62-53-3) Anthracene (120-12-7) 1-Anthramine Y6JQ-49-1) 2-Anthramine (613-13-8) Auramine (492-80-8) tSenzraJanthracene (55-55-3) [BA] Bezizraloyrene (bO-32-8) iKHl Benzfal pyrene 4,6-oxide (37674-47-3) TBP 45-oiidel BenzMpyrene (191(-97-2) Berrllmm znlfaie <77B7-5t>-6) Biz-dichlororoethyl ether (642-88-1) Bii-(p-dimethylaxnino)diphenyImethane (101-61-1) Bromobenzene (1U8-86-1) 5-Bromo-2'-deoxyuridine (59-14-3) TBrdUrdl 74Bromomethyl)-12-methylbenzfalxnthricene (16238-56-5) 1.4-Batanesultone (1633-83-6) c-Cmprolactone (602-W^T) o-Chlorovuiine f95-&l-2) p-Chtarouiilins (106-47-8) Chrvsene (218-01-9) 4-Diethvlat7iinnziobenzene (2481-94-9) l^;3.4-Diet>oxvbutai)e (1464-53-5) (DEB) 44A?Ji(-Dimethylamino)azobenzene (60-11-7) rDAB1 2'<3-Dimethyl-4-aaiinobiphenyi (13334-86-0) 7,9-Dimethylbeturc]acri<iine (963-89-3) 7,12-L)imetnylbenire]*nthracene (57-97-6) TDUBA1 Dimethylearoamyl chknde (79-44-7) 1^-Dtmeth7lhrdr>rin (5-10-73-8) Diphenylnitrosamine (86-30-6) lJZ-Epoxybutane (106-88-7) EUiiomhe (13073-36-3) Ethvl-D-toluenesuKorkte (80-40-0) 5-Fluom*2'-deoxyuridine (50-91^5) [FdUrd] 2-Fluoremmine (153-78-6) |AF1 A/-2-FluorenyL&cetam73e (53-$6-3) [2-KAA] JV-4-Kluorenyixcetamide (28322-02-3) Glycidaldehyde (765-34*4) Glycidol (556-52-5) Hydrazine aullate (10034-93-2) 3-Hydroxybenx[a]pyreae (13345-21-6) pa-oi^r- ihso Earn tz-?.aaj_ ^zMi -XzSm -A- K-T^l K- IPSflA. --if-3 >43 x . K-4fl3t. ..ifcaaig K-34S4& /V-Nitrosocthylurea (759-73-9) Phenanthrene (SS-OUfeT j.-raenyl-a,j-dimethyltrmene~(7227-91-0) [PDMT] -PligfDart 17673-25-5 r XTa-Propanesulione iuzu-tT ^-Propiol&ctonc (57-57-8) (BPI/T Proppyyllei nimine (75-55-8) p-Kosaniline (S59-61-9) Safrolc (94-59-7) Succinic anhydride (108-39-5) iy-Ci-Tetrmjectrioylphorbol-13-acetatc (16561-29-8) ~Thioa.ceta.mide (62-S5-5t "Thiourea (62-56-5) litanocene dichloride (1271^19-8) o-Toluidine (95-53-4) P-Toluidine (106-49-0) o-Tolyaio)-o-toluidine (97-56-3' -Trlhydroxyantthhrryaeiine (480-: il mustara (66-757 Urethan (51-79-6) R&S 024709