Document oeMLOEdRENgGa8koMMraqpD8r
FILE NAME: Asbestos Corp Ltd (ACL) DATE: 1952 DOC#: ACL009 DOCUMENT DESCRIPTION: Medical Report from Thetford Clinic File
ALBERT CHAMPAME
fl
A lb e ri Cheisnegne
T hetford C lin ic P li* Ko, 2335
(Saranac L aboratory So* P-577)
Tb* d a te and n a te r i a l p e rta in in g to th e abare asne case ver* re c e lred
tram P eal C a rtie r M .D., D ire c to r o f th e T hetford In d u s tria l C lin ic ,
T h etfo rd KLaes The e o n s ls t o f th e follow ing*
1 . A betract o f occupational h la to ry 2 . A bstract o f m edical h is to ry 3. Chest roentgenogram s .' Gross tis s u e specimens o f th e lu n g , h e a rt,
l i r e r , sp leen , and kidneys
Age* 63
Pled tforsaber 2 2 , 1952
Occupationa l TUa to m A sbestos C o rporation L td.
P r illa r - open p it
Bagger T easetar T in a s!th Shop
3 year*
1 7*a r 39 y asra 2 year*
"A part from 1 y e a r a s a b ag g er, t h is employee o a d d n o t be considered to h are worked in d o st o ccu p aticaia.*
M edicai Hia t o m
f i r s t se rio u s illn e e e began In 1946 a t v h ich tim e th e employe took alrifc le a s e f o r ir- weeks because o f a bad cold* In 1949 he n o ticed tr a n s ito r y p ain in th e l e f t c h e s t and In b o th arms s p e c ia lly , a f te r e f f o r t. T h is van a sso c ia te d v ith in c re a sin g tire d n e ss The employee died suddenly
on B oreaber, 22, 1952 v h lle atten d in g a fam ily p a rty .
C hest ftocnW enojtrKssi
X nterpret& tiott o f stereograpbie chest roentgeao-
grams p u rp o rtin g to be th o se o f one '/ LBt rtX CHAMPAME,
b e trin g id e n tific a tio n /2335
datad Dae. 16, 1946
ASB2STOS OOBPOHA3IOB LID.
r
The diaphragms a re normal In p o sitio n and contour, b a t there I s a lig h t blunting of the le f t oosto-phraalc a n g le , and a suggestion o f b lu n tin g on th e rig h t The
*> s ilh o u e tte sad g re e t -reesele re w ith in n o n s l U n its . Trachea i s in the n id iin e , and th e upper sed ia -
s t i n t s la n o t widened.
-1-
llbert Chaapagne
P-577
8* ft I** The long fie ld a re d e e r , end th e re i no s n le rg m e s t o r d is to rtio n o f th e lung roots*
P ile o f 2/22/51 c o h e re d v ith th e sh o re, reveals*
B* ft L*
These I s now d e f in ite b lu n tin g o f th e l e f t c o sto -p h rsc lc e a g le , which extends e sh o rt d ista n c e op tb s l a te r a l &sp en t o f th e baaithorax* There i s e lso noted a very fin e 'c u rv ilin e a r urea o f Increased honogeaeous density along th e done o f th e haaeidlaphraga, baring the appear ance o f c a lc ific a tio n * There I s now seen clouding of th e extrexe l e f t apex and o u ter portion o f the 1 st a n te rio r l*s*
P H o f 3 /1 9 /5 3 , s p a re d v ith above, re v e a ls no change*
OrlhlOHt h ile th e fin d in g s i n th is c a s e a r e n o t ty p ic a l o f a sb e s to sis, i t i s tp iite conceivebl th a t th e chccges in both coato-phrenic s n ld , v ith associated thickening o f the p leu ra in th e se regions], e sp e c ia lly on th e l e f t , could be a very e a rly e a n ife sta tio u o f such a condition Severer, I b eliev e th a t th e den sity la tha l e f t apex, f i r s t acted in 1951 would, because o f i t s lo c a tio n , suggest th e presence o f e tuberculous lesion*
n vm a im
LZOSSD J BSZSTOL, KJD, Bead, Sept* o f Badiology**
P ress D escription
L ncret Tbs l e f t lung in o f about normal e lse b a t i s ex ten siv ely l e c e re te d b y th e ecb o ln er' a tro ca r* The p le u ra i s tom . b a t
i s g e n e ra lly cneoth end thin* The secondary lo b u la r sep ta axe sossvhst accentuated by th e presence o f blsc* piguent* The tis s u e i s g e n e ra lly honogeneoos in consistency* On se c tio n th e pulmonary tis s u e appears g en erally air-co n tain in g end the a lv e o li appear e sse n tia lly unifora in e ls e , though perhaps so&evh&t coerse* The secondary lo b u la r se p ta a re v e il seen end e re eoaevhat accentuated by b leak pigm entation b a t ere w ithout evidence o f excess fib ro u s tissu e* i t th e ex tras* apex o f the upper lobe th e re i s a narrow sons o f g rey sc a rrin g im m ediately beneath th e pleura and a ssu rin g 1 ce* in g re a te s t depth* V Ith in th is a re a o f s c a rrin g , th e re a re noted sev eral sooothly lin e d spaces varying up to 5 ra s . in d isa ste r a id in te rp re te d a s d isten d ed eapfayaesatous a lv e o li*
lbart Champagne
P-577
The rlg h t lung reseab lee th * l a f t .
Trechea and Brooctail 7b* trac h e and bxrmchi a ra o f a o rx sl s is a s
and th * lr v a lla a ra o f a o ra al tMcicsB. The
m e te l s geaexnlly la ta e t, aaooth and p a la .
. /'
T rscheobroacblal Lrgoh odas* Ths*a a ra o f aboot w m l s is e and:. c o n slrte n c y . Gn *e s tic o t i n r f a e a
ls sean to ba b la d t ln co lo r end ao lst
_
*
H^arti The hemrt i d ir tin e tly eslsrged h at th a cheabers o f tira tvo
sid a s seos c f n o n tsl r e l s t i r e sisas Tha sp le e rd iu s and
endocardio a ra evexTvhare aaooth ad t h la . Tha alea rin g s a re o f a o ro i
r a la tir a sisa s? end th a ir caspa a ra deIle o te tnd fre e ly creable* Iba
eorousry a r te r ia s a r le s s o m a l? ad fo llo v sotaaal eouraca, though th a?
a ra aooevbat to rte se On m aaro o s c ro a s se c tio a a l l T eesels a ra otad
to b a p a rtla U ? c * l Ifi d , a a p a d a lly 1 t b e i r p ra x is* ! p rtico s Tha
l a f t g a ta rio r deeeaadlag eesl shovs s a re ra l y e llo v a d e s e tlo plaques,
ntrrgw ing th a la s e n to ISA o r 1 /5 I t a Jio ra a l sisa Zn th a re c io s o f osa
o f th s s a plaques tb a ra l s g ray iab -red tbrss& ue s a te r la l ecludlag th a
e n a ll re a e la ia g lu s c a . Tha a y o esrd iu s l s f s r th a a o s t p s r t hoeogeneoo*
in c o lo r fiad c o a sls te a c y *nd c asa res 1.9 cas l s th lck aeea a t th a basa
o f th l a f t T c a trlc le j 0*8 es ou th a rlg h t E xasdnatim o f th a ayocardlua
ln th a in ta r r e a tr lc a le r eeptoa ne&r th a apaz rev eis ansaro* fin a gxay
stre e l o f acor tiasua Ib a ujoeardioa har, boverer, l s o f so n ad
th ic k n e s *
Aortas Tha a o rta l s soaavh&t la rg a r l a d la a e ta r th e a o ras! and i t a a l a r t i o l t ? l s d i s t la o t l? d lsla ish e d On a a c tie n th a re aro
notad sasero as y e llo v s o b is tia n l s c la ro tle plaques
Saleen* Tha sp la en l s s s e ll ead i t a cpenle le v rln k le d and g rey . On s e c tlo n th a tia s u a l e asen to b a sosaw bet cu to ly sed h a t
n o t o th en d e* reaarfceble*
L lrcr* Tba n rtic a o f l i r a r st& aitte d l s n o t reanricabl* l s th a groas croep t fo r eatolysls
Tldcee* Tba l a f t kldnay l s e f ebout noraal sica I t a capsul a
.
trip e v ith ansa t o r a r a d a ganar sl l y aaooth snrfnee --
elthough th a re a ra e c a tta re d depreded f o d carylng up to $ ase l a -
d la a e ta r On s a e tc a th a c o rte * nd u a d n lla a ra p raa en t ln normal
re a tic e sonata, azaapt l s th a s ite s o f th e depreseed s e trs notad
o x te rn a lly vbara th a c o r ta r l s cnaevhat thinned Tha c o rtic a l nd
-
e d a ilu ry aunrfclngt a ra n o x sa lly p ro sla e st
Tha rlg h t kldney r s a te la s th la ft
-3 -
CbftKpqgB*
^ C T 7 eccr> le
*-577
* * * * ta o f tfat niaoM . j 83* ^ ^ooa^ i* * io a s iirro lT la r
** 6k polats* tin
w * o n cad c o itln a s ii au^num
tS
F
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^ sS
S
^
S
t
h T * ^ tW ck*!i*d * ijrto rU d tori w.11** * "
it*aoo8 tb o n
5 S
5
,
a w n u a f o r a l . . , i t b . o f t t e ^ D? f ^ i f ,f t!> " * * * caim ot
S r t T m TM 1" " " * - V L .
10 d iu a ,
tont Iw m m ,
l ^ i" l o l r m u . .
* lw o l* .
-th * a f e o h w a . i . f *
of*
*ccop*Hi*d b y *o I n flu a e a to rr r * - * * * i13 t ^*# l tio * i* i
epical o f d a rt.
<*colocM o&
?*** aro a lly lo b u lar.
3 ** CW M *vn bodi*
"* " --
-
4 ? . " " T
"2
* 7 * " * * `<1 .
K tao. t b ^ S d f , ^ * 3**l l T t i , r , .
. **e^ .f * W'wUahly tb o m n l t o f f?*
P*r * * b y i. T b ai*
t a o o ttia -tee -prwwanrtiao f o r rto m L .* 1?***30
^chalcsl d iffic u lty
blood
* * * ^ ay r a a t. t S 1^
ttbt eroddbbil a**ro**n*o1t #dd0a0eooered. -J .t o n ^a ln^trsZp^u laOoaan^ry v4oWoco^lioaro l
.
aotTo o f a J a d ^ c t a r t ^ 1 breW -l*s or* uauanolly d ila te d
S ^ s U rl ^ ^ pi t S i ^ i n T i ^ ^ fs r * *
" '* * f i w c t * i , 5 E S u 4 ? "
" ooUu
lib a rt Cbanpegne
P-577
T rachaobropohlel Lroroh Sodas
I ha nodes e x h ib it sc a tte re d black plgnent, ao et concentrated la
.
th a w d n lla ry p o rtio n o f th e nodes. The p lg sso tad areas show a lig h t
in e ra tse la re tic u la r fib e rs . In g e n eral, hovever, th ere la only aa
e rtre a e ly a ild tis s u e r e s ponse to tb a p ig n e a t. A sbestos bodiaa e ra
n o t discovered in tb a node.
H rartt .
Tba yocerdinca p a rtic u lc riy in actio n s o f the l e f t v e n tric le end o f th e aeptoa, re re e ls fo ca l sod lin e a r patches o f fib ro s is vhich o b lite ra te sad reraise ap p reciab le sre c s o f sa c c le . ILeevhere the n u clei a re o ften enlarged in re ls tio n to the resp ectiv e aaecle bundle. T his featu re suggests th e presence o f ayocexdlal hypertrophy.
H im
.
"
There ia no rossarkable ab& ozxelity.
2ls,mi
There i s nothing s ig n ific a n t.
P o st aaorten change i s pronounced.
'lUi-,
Tbs c o rte x sh o w -widely a ep sre ted lin e a r fo c i o f eeaxrlag vbieh e re o fte n ric h l a a a s il round c a lls . The gloessruli v ith in such fo c i e re h y clin ix ed and th e tubules a re o b lite ra te d . The s r te ric le s rev eal an - i^ re d e h ie in id e a l thickening o ften x itb Iso st coaplete oeeluaioa o f tb a re s p e c tiv e lu n en . These ebs^ges a ra In te rp re te d u arcldaaoe o f a m oderate arte rlo lo -n e& h ro sc le r tx ia . Zn a d d itio n to th e above, 11 sections ex h ib it poet aortaa change.
cosea^i
_
The pulaonary changes p ertain in g to tba ex tan t o f fib ro s is end th e decree o f aphyE*. e re indeed oinia& l. Tbet fib ro sle occurs in a e so d stio n v ith d e p o sits o f black, p a rtic u la te plg&ent and an occceional l H fom ed ^w sbestoslc, body. S ev erer, n o t 11 d e p o sits o f b in d : p lgseut a re accoapanied by f ib r o s is . T his fe a tu re suggests th a t a t le a s t sene o f the d a rt, had a low b io lo g ic a l a c tiv ity . Tbs o th e r p o s s ib ility i s th a t th a t d n a tl v&a d ep o sited a t a r e la tiv e ly re c a s t d ate and th e re fo re d id c o t have tin * to ex ert i t s adverse inflneaoe before death of the p a tie n t.
The fo c a l pulmonary hecorrbage l a In te rp re te d a s an w t l e o r te i events I t probably occurred texsdnaU y a s^ is re la te d to b is cexdip-veacular d isease. T hat d ise a se v as a p p aren tly a syertes&e one. Although i t provoked a card iac
- 5-
A lbori Chaapogne
?-577
f a llu r e T o ro !tin g iT oa ia rc lT a * n i o f tb corooaxy
n a re rth a le a a
i t app**r* th c t th di*** w b c d c a lly tthypart^neioo vhich ve# re
f i sctd al*o In * a o d e r* t lj adm nced rta rlo lo -n o p h ro o d o ro ^ lr. Tbcrm
l a no ridono* ib a t hyprt#cjdoc od l i * eonee^uent cordio-T **cular-
re n a i d i* * * se- ber* a re la tio a sfc ? io ih in b a la tlo n o f &sbe?toa d u a i,
o r io i t * pulnoaery d rp o sitlo n end rscu lt& n t asbesto t ic flb rc c la stic
s p r* s? a t in ih* ina o f ih te # # an d ar rerlaw *
O rin i onr
I t l e ay o p inion tb n t lb c r t Cbsmpsgn d i od o f prinfcry c a rd io r a r c u le r ro an i dlse&s v ith con#eqttent s c i ro si* o f t i eorontry veaaelc
end fib ro s i o f th o EyocanllsBB imd v i t i n o d * rst ly cdrancod n a iru s c i ro r*, vhich. h&r no a p * d ile re la tio n h ip to hi* em patie. 81* lung* xhlblt
n lr *. V3TJ e l i A & sostctl fib ro s i vhich i s dl*corTd jx itto lo g io a lly
b a t vhich vr9 a o t s u f f le lo a tly d fla d f o r d atectio n . rocntfirnagrt-phicA lly darla lif * .
I r t h a r T e rre ld , R.B. P ro f a* er, D *psrtent o f I n d u ttr ic i Medicin bay** Q nlrer& ity C ollage o f M edicine D e tro it, M ichigan