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E . 1. d u P o n t d e N e m o u r s S C o m p a n y
IN CO R PO R A TCO
W i l m in g t o n , D e l a w a r e 19898
POLYM ER PRODUCTS DEPARTM ENT
EXPERIM ENTAL 51 ATION
PERSONAL AND COKFIDEITIIAL
c c : A. J . Dahl B. V.7. K a rr h L. J . Papa Pral F ile I.C .
- K i l t OC - ZCy
SA Z 2 4 > ' / )
October 27, 1981
j.u: FROM
DR. Y. L . FOETH - PPD, P a r k e r s b u r g S. S . STAFFORI
ANALYSIS OF BLOOD SAMPLES FOR PERFLUOROOCTANOATE (Job No. 810- 5 7 8 ; PRAL Nos. 81- ^ 598- ^ 6 2 7 ;
_________N o tebo ok K o s . E2251i* ,E 26238,E 27Ji 3 2 )
As r e q u e s t e d ir. y o u r l e t t e r o f 10/ 6/81 t o L. J , P a p a , t h e 30 b l e e d samples submitted then have been analyzed fo r perflu oro octan o ate (Cg) by the usual gas chromatographic method ES-567. R e s u lts and sample id e n t if ic a t io n are given in the attached ta b le .
Attachment jah
Key Words: Perfluorooctanoate GC Blood Analysis
Therp s a w o rlc o: thinpF w t >t S o m e E n m e lh n p ab en r
00015G
EXP000063
EID713877
TABLE I CONCENTRATION OF PERFLUOROOCTANOATE IN BLOOD (a)
Sample PRAL No. Date_ Sampled
01- 1*598 81- 1*599 81-14 600 61-1*601 8I-I4602 81- 1*603 8I-I+60I* 81-U605 8I-I4606 81-U607 81-I+608 81-U609 8 1 - I161C
82- U611 61-U612 81- 1+613 81-U61** 81-I615 81-6616
61-U617 81-1*618 8l-l*6l 9
8 1 - 1*620
81- 1*621 81-1*622 81- 1*623
81-1*621*
8 1 - 1*625
81- 1*626 81- 1*627
9/22/81 9 /23/81 9/23/81 9/2-/81 9 /21/81 9 /21/81 9 / 25/81 9 / 25/81 9 / 25/81
9/ 28/81
9/28/61 9/28/81 9/28/81 9/ 29/81 9 / 29/81 9/ 30/81 9 / 30/61 9/ 30/ c i 9/ 30/81 10/1/81 10/1/81 10/1/81 10/ 1/81 10/1/61 10/1/81
10/2/ei
10/5/61 10/5/81 10/ 5/61 10/ 5/53
P.R.No .
1* 1*90
W.S. 1*293 3872 181*3 W. S.
1572
W.S. W.S.
1*380 1*621
1*097 W.S. 3708 W.S.
W.S. 1632 1762 6533 6778
W.S.
872 31+71+
1* 1*953 31*90 1*057 1727
W.S.
W.S.
1972
Name
GC Analysis____________________ <b) Date Analyzed [Cr ], w e F/r blood
10/9/61 10/ 9/61 10/9/61 10/9/61 10/9/61 10/11/81 10/11/81 10/11/81 10/11/81 10/12/81 10/12/81 l C / 12/61 10/12/81 10/12/81 10/12/81 10/12/81 10/23/81 10/12/81 10/13/81 10/lU & 10/23/81 10/13/81 l C / 13/81 10/13/61 10/13/81 l O / l k /81 l C / 13/81 10/13/81 10/13/61 10/ 13/61 1 0 / 13/81
0.10 0 .2 7 O .ll C.26 0.18 C . l +5 7 .5 D.95 0.C70 0.66 0.12 0 .1 7 0.0 8? 0 .2 5 0.12 0.98 1* .9
0.63 C . 22 C .0093 0 .3 5 0.62 C .17 0 .0 5 9 8.2 0 .2 7 C .26 0.20 0.060 1 .C
000157
REDACTED*
EXP000064
EID713878
TABLE I (COHT'D)
A n a ly s is as d e s c r ib e d in Lab Method ES-567 ( "D eterm in atio n o f P e r f lu o r o o c t a n c ic A cid in B lood, Gas Chromatographic Method", S. S t a ffo r d , k/3/8l ) , u sin g the p a ch e d column GC a n a l y s i s v i t h p e r f l u o r o - n - o c t a n o i c a c i d a s c a l i b r a t i o n s t a n d a r d .
Although the a n a ly sis is s p e c ific a lly fo r perflu orooctan cate (acid or s a lt s ) , c o n c e n t r a t i o n s a r e g i v e n i n ppir. f l u o r i n e f o r c o m p a r is o n v i t h t h e r e s u l t s o f t o t a l o r g a n i c f l u o r i n e a n a l y s e s . (ppm F = 0.6SB x ppm p e r f l u o r o o c t a r . o i c a c i d ! E s t i m a t e d u n c e r t a i n t y i s _+ 10? r e l a t i v e s t a n d a r d d e v i a t i o n . The l o w e r l i m i t f o r q u a n t i t a t i o n i s 0 . 0C7 p g F / g . The d e t e c t i o n l i m i t i s a, 0 . 001* p g F / g , t u t c o n c e n tra tio n s in th a t range cannot be w e ll q u a n tita te d and are rep o rted as < C. CC7 . Hone d e t e c t e d ( n . a . ) i s r e p o r t e d f o r sa m p le s v i t h [ Cg] ^ O.COe ppm., vh ich cannot be d is tin g u is h e d from rea g en t background.
000158
EXP000065
EID713879
