Document oe3vLZYR3Yj9a338EkO6EgRzw

NOV-06-2002 WED 04:26 PH SHEPARD HOFFMAN ESQ FAX NO. 2145220420 P. 16 PULMONARY ASBESTOSIS III: CARCINOMA OF LUNG IN ASBESTO-SILICOSIS KENNETH M. LYNCH, M.D., and W. ATMAB SMITH, M.L. {From the Departments of Pathology and Medicine, Medical College of the State of South Carolina) Primary carcinoma of the lung has attained a position of major in terest in malignant neoplastic disease, through at least a more common recognition, if not more frequent occurrence, within recent years. Likewise asbestosis has assumed a rank of considerable importance in industrial medicine. Workers in the mines of the Era Mountains, on both the Bohemian and the Saxon sides, have suffered heavily for some centuries from pul monary disease now recognized as carcindma and woll known as Schneeberg and Jachymov (Joachimstal) lung cancer. Pirchan and Sikl (1), in a report upon a series of those cases, Btate that "there were only moderate degrees of anthracosis," and they, are not inclined to attach any particular importance to the degree of pneumonoconiosis as a cause of the cancer, but consider that "the question may be somewhat different with regard to the quality of the foreign substance deposited in the lung." Chemical analysis in one of their cases revealed ` ` only calcium, magnesium, aluminum, silicic acid, chlo rides, and phosphates ; no trace of arsenic, bismuth, cobalt, nickel, or uranium was found." They lay suspicion, as others have done, upon radium emanation and upon arsenic, both factors being encountered in the Scbneeberg and Jachymov mines. Rostoski, Saupo and Schmorl (2) found severe "anthracosis" in Schneeborg minors the subjects of lung cancer and are inclined to at tribute tho causation of the cancer to the anthracosis, while Simpson (3) states that pulmonary cancer is a rare complication of silicosis in South African miners. Schulte (4) has reported lung cancer in pneumonoconiosis among coal minors, and Saupe (5) has recorded two cases in arsenic miners. There appears to be no previous report of its oc currence in asbestos miners or mill workers, although the record of autopsy examinations of cases of asbestosis is not large. As worthy of record in tho interest of both diseases, as well as their possible relationship, the following case of pulmonary asbestosis with associated carcinoma of the lung is reported. Case Rjspobt A white man, fifty-seven years of age at tho time of his death, first came under observation at the Sliirras Dispensary of the Ropef Hos pital on Jan. 10, 1934, at which time he appeared very old, weak, and 56