Document oM7RvpZmjLV3gqLBVry7z9veg

Cases of T E L poisoning I. G. F arben M anufactu F rose-H arz M ountains, Oi to irt 2 Ki o z =3 O o 3 ~QGj 13 o CO Xo 0 >z 0o z 2 cTvn 2 year-a In the chamber at a lead In air concentration of .075 mg. per cubic meter has been out of the chamber since the end of 1^52. To date the post exposure results on this subject indicate that he has returned to essentially the same lead equilibrium, as judged by urinary excretion rate and blood concentration as existed before exposure* The second subject. Hris now in the chamber on a schedule Identical with the first subject. However, the chamber lead In air concentration is now .150 mg. par cubic meter, fr. first entered the chamber at the above concentration yeb. l6th, 1555* His exposure was discontinued from Fob.`25th tan til April 17th, while we investigated a sampling artifact with the electrostatic precipitator at low sampling rates. The present status of this investigation is given In memorandum attached. The month exposure since April 17th to date has resulted in raising the subjects lead blood level to approximately .035 mg./lOOg. and his urinary concentration to approximately .07 mg./L. These values are substantially higher than his pre-exposure values* and are generally in line with values expected. X'N r\ 0020825 . y- Uf.' STVTBS 0? LHAD THKALAFIOH f*THDT A3 OF v AT 1&. 1955 The first subject, Mr. spent approximately 7 hours par day, 5 days per week, for a period of approximately 2 years in the chamber at a lead in air concentration of .075 mg* per cubic meter has been out of the chamber since the end of 1952* gbL_aatB-dthe-.peg-fe exposure ratnslta on this subjact 'Indicate that he has returned to essentially the same lead equilibrium, aa Judged ^ /**.; ?&j -sr *<u ** 1: #u/. $&\vnrln&ry excretion rarfee and concentration <&ea*a6&fee$ diafxu^-expbi^ The second subject, Mr. is now in the chamber 'tl' on a schedule identical with^the first subject* However, the chamber lead la air concentration is now .150 mg. per cubic meter. Hr. Creech, first entered the chamber at the above concentration Feb. l6th, 1955* His exposure was discontinued from reb. 25th until April 17th, while we investigated a sampling artifact with the electrostatic precipitator at low sampling rates. *ihe present status of this investigation is given in memorandum attached. The ij men th'Wxpo sure since April 17th to date has resulted in raising the subjects lead blood level to approximately .055 mg./lOOg. and his urinary concentration to approximately .07 aig./h. ^Shese */' c *4v Zh~ values are substantially higher than b|?3fc^ga2es^^ and are generally in line with values expsated* f Kf 0020826 ~'t f-fpTT' :AD The first subject, w^ aPent approximately 7 hours per day, T days per week, for a period of approximately 2 years in the chamber at a load in air concentrafelon of .O75 mg* per cubic meter has been out of the chamber since the end of 1^52. To date the post exposure results on this subject indicate that he has returned to essentially the same lead equilibrium, as judged by urinary excretion rate and blood concentration as existed before exposure. The second subject, is now in the chamber on a schedule identical with the first subject. However, the chamber lead in air concentration, is now .150 rag. par cubic meter, hr. rst entered the chamber at the above concentration Teh. l6th, 1955* His exposure was discontinued from Teb. 25th until April 17th, while we investigated a sampling artifact with. the electrostatic precipitator at low sampling rates. The present status of this investigation is given in memorandum attached. The month exposure since April 17th to date has resulted in raising the subjects lead blood level to approximately *055 mg./l00g and his urinary concentration to approximately .07 ag./L. These values are substantially higher than his pre-exposure values, and are generally in lino -with values expected. KH 002082? LHAP. iih t a l a : ^'T70"\r MU^m \\ The first subject, Ur who spent approximately 7 hours par day, f; days per week, for a period of approximately 2 years in the chamber at a lead in air concentration of .075 sag. per cubic meter has been out of the chamber since the end of 1952* To date the post exposure results on this subject indicate that he has returned to essentially the same lead equilibrium, as judged by urinary excretion rate and blood concentration. s existed before exposure* The second subject, Ksr* is how in the chamber on a schedule Identical with the first subject. However, the chamber lead In air concentration is now .150 mg. per cubic motor. :.:r* first entered the chamber at the above concentration Teb* loth, 1955, His exposure was discontinued from Fob*.25th until April 17th, while wo Investigated a sampling artifact with the electrostatic precipitator at low sampling rates. The present status of this investigation is given in memorandum attached. The month exposure since Aprl 1 17th -to-date has resulted lit raising the subject's lead blood level to approximately *035 mg./lOOg. and his urinary concentretion to approximately .07 * /-^V # These values are substantially higher than Ills pre-exposure values, and are generally in line with, values oxpaated. K? 0020828