Document oD0LMNnndEbZOQmGv0ma0ZQOw

UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY. TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) 2-Acetylaminofluorene (53-96-3) Suspect cancer agent Teratogen Acrylic acid (79-10-7) 0,3 WT^ )H fit? C fiC*1 l> IKhce Amours /fJ) TAR $ OTTOns MnfO fit >05 Acrylonitrile (107-13-1) Known human carcinogen Teratogen fgr Iftz As Low As Practical (UCC) 2 ppm (UCC) 2 ppm ' 10 ppm C (OSHA) : 4 -Aminodiphenyl (92-67-1) Known human carcinogen N.D. Asbestos (1332-21-4) Known human carcinogen 2,2'-Azobis- isobutyronitri le (78-67-1) As Low As Practical (UCC) $02VARM5 PARTS AROilUp Th ?t-AHT STARTS F/icKifiC t- $lAtUU?Ti, utlv. iCWM root- RgOM 10 Fibers/cc C 2 Fibers/cc >5 urn long (OSHA) 0.5 ppm 2 ppm STEL (UCC) U.C. Corporate HERB (Approved 1 March 1982) UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST: , (See Reverse Side) .... ... . . - - ;:4 NOTES OF EXPLANATION; 1. A material is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. '- , (c) "N.D." indicates that informatiqn has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for whi:h there is Insufficient evidence that the substance causes cancer in man. 3. Teratogen means a chemicalfrju.bslance or physical agent which causes abnormalities in structural'nd/orffunctional development during gestation. -V. }. -i.r, ` Vr.\ U. C. Corporate HERB Accepted: 1 March 1982 BRB 0488 Page _2_ of 14 union carbide-Internal exposure standards list BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and. Definitions). T . ' wV' ,> C- * ' 1 SUBSTANCE (CAS No.) i CARCINOGENICITY TERATOGENICITY ! OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) Benzene (71-43-2) Known human Ufa Benzidine (92-87-5) Known human carcinogen IM3 Teratogen 1 (See Footnote A) 7 N.D. Xj-rr 10 ppm 25 ppm C 50 ppm/10 min peak (OSHA) As Low As Practical (UCC) Benzidinederived dyes 0'V>lWinE 114-42-1 Benzyl Chloride (100-44-7) Ci-1 ' Knowq human carcinogens ** Bis-2-Chloroethyl ether (111-44-4) N.D. . Uir^ N.D. N.D. (R) I** As Low As Practical (UCC) 1 ppm (OSHA) : - - 15 ppm C (Skin) (OSHA) Bis^-2-Chloro- Known human ethyl-2-naphthyl- carcinogen ami ne (494-03-1) N.D. As Low As Practical (UCC) Footnote: (A) Teratogenic only in presence of maternal toxicity (R) Revision from previous list i:: U.C. Corporate HERB (Approved 1 March 1982) BRB 0489 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST ., - (See Reverse Side) NOTES OF EXPLANATION: 1. A material is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB), 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current - updating procedure. Those so marked will 'e reviewed at the earliest convenient time. r> ,\v "Mr4 .. ,'V. , j. ^*5* "> "Vjv , (b) Entries marked with a`double asterisk (**) indicate they are under continual review because Sf^current deficiency of relevant credible data. : (c) "N.D.M indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. v DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. ..Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. 3^ ..Teratogen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation. U. C. Corporate HERB Accepted: 1 March 1982 BRB 0490 gSiftgg ;:C:;' r/A.'? ' > 'BU > ' ,':'K. UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST Page _3_ of 14 BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY ' (See Reverse Side for Explanations and Definitions) i SUBSTANCE (CAS No.) :1. i b v ' CARCINOGENICITY TERATOGENICITY Bis-Ch1oromethyl Known human ether carcinogen (542-88-1) f N.D. Cadmium Suspect cancer (7440-43-9) agent Teratogen / 1 OTHER " SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) HP As Low As Practical (UCC) ______ :---------(R)-,, 40 jjg/m3* 200 pg/m^ C (UCC) Carbon tetra chloride (56-23-5) Suspect cancer agent (-) Embryotojjic 2 ppm* 4 ppm C (UCC) Chlorodifluoromethane (Fluorocarbon-22^ (75-45-6) Teratogen* Chloroform (67-66-3) ' , = Suspect cancer agent Teratogen 5TOPF9 4-Reforms <, 1000 ppm (ACGIH) Mb U>X 2 ppm* 4 ppm C (UCC) ' Chromium-6 compounds Suspect cancer agents tf 51 PC,. \j?f 0.05 mg/m^ (as Cr) (ACGIH) Footnote: (R) Revision from previous list U.C. Corporate HERB (Approved 1 March 1982) BRB 0491 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST (See Reverse Side) NOTES OF EXPLANATION: 1. A material is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will be reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are undecontinual review because of a current deficiency of relevant credible data. 1 ' t.\ (c) "N.D." indicates that-i:i information has not been located to allow a decision on carcinogenicfor teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. - '' A 2. Suspect Cancer Agent mean's^insubstance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. 3. Teratocen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation U. Cv Corporate HERB Accepted: 1 March 1982 BRB 0492  j,t'' -"r. 'V .*: - .-.f Page _4 of 14 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions)- SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY ' OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) Di-Sec-butoxy- Suspect cancer acetophenone agent* (68109-57-9) N.D. No skin or oral contact (UCC) 3,3'-Dichlorobenzidine (and salts) (91-94-1) Suspect cancer agent(s) N.D. Diethyl sulfate Suspect cancer (64-67-5) agent N.D. Diisopropyl sulfate (2973-10-6) Suspect cancer N.D. agent (See Footnote A) 1,2-Qimethoxyethane (110-71-4) Teratogen Dimethylacetamide (127-19-5) N.D. Teratogen As Low As Practical (UCC) 1 ppm No skin or oral contact (UCC) -- ' 1 ppm No skin or oral ' contact (UCC) 10 ppm TWA *(Skin) 25 ppm STEL (UCC) (R) 10 ppm 1 No skin contact (OSHA) Footnote: (A) Limited evidence for carcinogenic potential in humans, but insufficient to conclude that the material is a known human carcinogen; i.e., is a suspect human carcinogen. (R) Revision from previous list U.C. Corporate HERB (Approved 1 March 1982) BRB 0493 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST (See Reverse Side) T" NOTES OF EXPLANATION: 1. A material is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will be reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) inoicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D." indicafes that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS; 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. 3. Teratooen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation U. C. Corporate HERB Accepted: 1 March 1982 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations arid Definitions) V : SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY -v OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) 4-Dimethyl amino Suspect cancer azobenzene agent (60-11-7) Teratogen Dimethyl formamide (68-12-2) Teratogen* No exposure* (OSHA) > LAB }X*T 10 ppm No skin contact (OSHA) Dimethyl sulfate Suspect cancer (77-78-1) agent N.D. Dimethyl sulfoxide (67-68-5) N.D. ... Teratogen 1,4-Dioxane (123-91-1) Suspect cancer agent N-Dodecyl mercaptan (112-55-0) s (R) 0.1 ppm No skin or oral contact (ACGIH) \&ftl . 'A'; ' _ .. ' , . . v < 10 ppm* No skin contact (UCC) : ' " Z`. t : > * 50 ppm* No skin or oral contact (UCC) 0.5 ppm (UCC) Footnote: (R) Revision from previous list U.C. Corporate. HERB (Approved 1 March 1982) BRB 0495 ' lit;-:' UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST (See Reverse Side) rr* NOTES OF EXPLANATION; t ,> 1* A material is included or. this list following a detailed evaluation ofpublished1 toxicological, medical, epidemiological and other relevant information by the Unir . arbide Corporate Toxicology Assessment and Advisory Committee (TAAt. and subsequent review and acceptance by"the Corporate Health Effects ..eview Board (HERB), 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will be reviewed at the earliest . convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. ................... (c) "N.D." indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a givert^ffect. DEFINITIONS; * 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that|t!}e substance causes cancer in man. 3. Teratoaen means a chemicaf^utfst^ce or physical agent which causes abnormalities in structural^And/orJunctional development during gestation. U. C. Corporate HERB Accepted: 1 March 1982 BRB 0496 Page of 14 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) Dripolenes-A,B,C Suspect cancer N.D. agents (See Fop.tn.ote A) 600 pg/m3 Ho skin contact (UCC) Epichlorohydrin Suspect cancer (106-89-8) agent N.D. 0.5 ppm (UCC) Epoxy resin Suspect cancer ERl-2774 agent (25068-38-6) N.D. Epoxy resin ERL-4205 (2386-90-5) Suspect cancer agent N.D. Epoxy resin ERL-4206 (106-87-6) Suspect cancer agent N.D. Epoxy resin Suspect cancer ERL-4234 agent (26516-47-7) N.D. ^ ) 10 ppm No skin or oral contact (UCC) UTTTFZ ^ hrrfi c/fp 1 10 ppm No skin or oral contact ' (UCC) 10 ppm No skin or oral contact U-- (UCC) j * 10 ppm No skin or oral contact (UCC) Footnote: .(A) Standard based on suspected presence of Polycyclic Aromatic Hydrocarbons U.C. Corporate HERB (Approved 1 March 1982) BRB 0497 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST- - [See Reverse Side) ~`; NOTES OF EXPLANATION: 1. A material is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and c*-er relevant information by the Union Carbide Corporate Toxicology As essment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current . updating procedure. Those so marked will be reviewed at the earliest . ' convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. v - (c) "N.D." indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. 3. Teratogen means a chemical substance or physical agent which causes . abnormalities in structural and/or functional development during gestation U. C. Corporate HERB ---Accepted: 1 March 1982 BRB 0498 Page _7_ of 14 t UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) . 2-Ethoxyethanol (CELLOSOLYE) (110-80-5) N.D. Teratogen 50 ppm C (UCC) Ethylene dibromide (106-93-4) Suspect cancer agent ' 0.1 ppm (UCC) Ethylene dichloride (107-06-2) Suspfect cancer agent (-) Ethyleneimine (151-56-4) Suspect cancer agent:. ** (R) Ethylene oxide (75-21-8) Suspect cancer agent (R) - 5 ppm (UCC) Embryotoxic (R) r L l As Low As Practical (UCC) 5 ppm (UCC) Ethylene thiourea (96-45-7) Suspect cancer agent Teratogen As Low As Practical (UCC) Footnote: . (R) Revision from previous list U.C. Corporate HERB (Approved 1 March 1982) BRB 0499 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST (See Reverse Side) ~ ' '-yj NOTES OF EXPLANATION: 1. A material is.included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will be reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D." indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient ... credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. 3. Teratogen means a chemical substance or physical agent which causes ..abnormalities in structural and/or functional development during gestation U.,.C. Corporate HERB Accepted: 1 March 1982 Page of 14 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) 2-Ethylhexyl acrylate (103-11-7) Suspect cancer N.D. agent (See Footnote A) Formaldehyde (50-00-0) Suspect cancer agent N.D. Ihs 5 ppm (UCC) 2rr 2 ppm (ACGIH) Formamide (75-12-7) N.D.* Teratogen Fuel oil residues Suspect cancer N.D. agents (See Footnote B) Hexafluoroacetone, * (684--16--2) N.D. Teratogen Hydrazine (302-01-2) Suspect cancer agent (-) 20 ppm No skin contact > (ACGIH) As Low As Practical (UCC) ^3 0.1 ppm No skin contact (ACGIH) roo on 1 ppm* (Skin) (OSHA) footnote: .(A) Based on chronic skin painting study: To be reviewed on completion of Inter-Industry Acrylate Committee Chronic Toxicity Study. (B) Standard based on suspected presence of Polycyclic Aromatic Hydrocarbons U.C. Corporate HERB (AonroveH 1 March 1QR?i BRB 0501 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST >' (See Reverse Side), NOTES OF EXPLANATION; 1. A material is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Comrttee (TAAC) and subsequent review and acceptance by the Corporate Hea th Effects Review Board (HERB}. 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will be reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D." indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. > DEFINITIONS: 1. Known Human Carcinooen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man.3 3. Teratogen means a chemical substance or physical anent which causes abnormalities in structural and/or functional development during gestation U. C. Corporate HERB Accepted: 1 March 1982 I BRB 0502 Page J_ of 14 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) Hydrogen Sulfide (7783-06-4) / IfOTVRE WTtLE ** Chemical . 10 ppm Asphyxiant (OSHA) (R) Itaconic Acid (97-65-4) 5 mg/m3 (UCC) Lead . $^ yAfrp 7439-92-1 Vet 70 \\>7 / xlmvoxwE io is ' ** hlFTATA >L& LtfiD IflRRAcrrhTf. )W06t [/* Teratogen y* * /\ir )0OS ffrt Soh Ifi 13 1 LEAP RtTAATE Leap wwwf metal >r> )/r )A& 50 pg/m3 Lg, 30 pg/m^ vem Action Level (OSHA) Mercury Alkyl Compounds Teratogens* ii\& Mercury, All compounds except Alkyl MFTA-l v ML ft? riMZy&tiTF[X.lrS, W1TKH-TE &LB OAlPE yH Lg 0.01 mg/m^ (as Hg) (ACGIH) .> \ frFTAl /r1 >* then 2-2^ ' C 0.05 mg/m^ (as Hg) (ACGIH) 2-Methoxyethanol (Methyl . CELLOSOLVE R ) (109-86-4) UhZ ' rr Teratogen ,uc 10 ppm TWA(Skin)* 25 ppm STEL (UCC) (R) Footnote: (R) Revision from previous list U.C. Corporate HERB (Approved 1 March 1932) BRB 0503 j .i : -- ,v- -vO UNION CARBIDE. INTERNAL EXPOSURE STANDARDS LIST'T-^ 7` (See Reverse .Side) ~ /. NOTES OF EXPLANATION:1 2 3 1. A material Is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. this listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified:by TAAC as part of a current updating procedure. Those so marked will be reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D.M indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. Teratocen means a chemical substance On physical agent which causes abnormalities in structural and/or functional development during gestation.' c U. C. Corporate HERB Accepted: 1 March 1982 It:,\v: c BRB 0504 Page 10_ of 14 I UNION CARBIDE INTERNAL~EXP0SURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) Methyl chloromethyl ether (107-30-2) Known human carcinogen N.D. OSHA Standard 4,4-Methylenedianiline (101-77-9) Suspect cancer agent N.D. 1-Naphthylamime ** (134-32-7) N.D. 0.1 ppm No skin or oral contact (ACGIH) OSHA Standard 2-Naphthyl amine Known human (91-59-8) carcinogen N.D. OSHA Standard Neopentyl glycol diacrylate (2223-82-7) :* Suspect cancer agent N.D. Nickel. Inorganic Compounds Suspect cancer agents No skin or oral contact (UCC) /A* mXfiohkwe '^oi ti>. AcerflTF i us n, )us ?i> SulfATfSelvTitu 1 ft 1 mg/m^ (OSHA) U.C. Corporate HERB (Approved 1 March 1982) BRB 0505 ,;>h UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST ' (See Reverse Side) NOTES OF EXPLANATION: r 1. A material is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ' ones modified, when TAAC and HERB determine that there is sufficient X' credible evidence for such as action. 3. (a) The entries marked with an asterisk {*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will be reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) UN.D." indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine^that a material does not cause a g-iven effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. 3: Teratogen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation. ;U- C. Corporate HERB Accepted: 1 March 1982 BRB 0506 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOSENIJITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY Nitric Oxide (10102-43-9) Bloc. Wt, Chemical Asphyxiant EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) 25 ppm (OSHA) Nitrobenzene (98-95-3) N.D. Chemical Asphyxiant (R) 4-Nitrodiphenyl Known human (92-93-3) carcinogen N.O. 2-Nitropropane (79-46-9) ______________ ly Suspect cancer agent 1 ppm (Skin) (OSHA) (R) No exposure* (OSHA) 25 ppm* (OSHA) N-Nitrosoamine compounds Suspect cancer agents* No skin or oral contact (UCC) N-Nitrosodimethylamine (62-75-9) Suspect cancer agent (-) (R) Footnote: (R) Revision from previous list U.C. Corporate HERB (Approved 1 March 1982) Embryotoxic (R) OSHA Standard UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST (See Reverse Side) NOTES OF EXPLANATION; 1. A material Is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will e reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D." indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given.effect. V ' - DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine .that the material has caused cancer in humans. J. 2. Suspect Cancer Agent means7a'substance for which there is credible scientific evidence, based on^animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man.3 3. Teratogen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation. U. C. Corporate HERB Accepted: 1 March 1982 BRB 0508 Page 12_ of 14 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) N-Nitroso-NPhenylhydroxylamine (148-97-0) Suspect cancer agent Perchloroethylene (127-18-4) ** (-) Polychlorinated biphenyls(PCB's) Suspect cancer agents " ^ Embryotoxic B-Propiolactone (57-57-8) Suspect cancer agent N.D. * 50 ppm (ACGIH) 3 pg/m3 No skin contact (UCC) OSHA Standard Propylene oxide (75-56-9) Pyrolysis fuel oil Suspect cancer agent N.D. Footnote: (A) Standard based on suspected presence of Polycyclic Aromatic Hydrocarbons U.C. Corporate HERB (Approved 1 March 1982) 20 ppm 100 ppm STEL (UCC) 200 pg/mo 600 pg/m C* No skin contact (UCC) BRB 0509 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST (See Reverse Side) NOTES OF EXPLANATION: 1. A material Is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will e reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D." indicates that Information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. v DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man.3 3. Teratogen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation. U. C. Corporate HERB Accepted: 1 March 1982 BRB 0510 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY, TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) Quench oil CARCINOGENICITY TERATOGENICITY Suspect cancer agent N.D. OTHER SIGNIFICANT TOXICITY EXPOSURE STANDARD .F0LL0WE0 BY UNION CARBIDE (SOURCE) 200 pg/mij 600 pg/in C* . No skin contact (UCC) Radiation Known human carcinogen Teratogen* Resin B condensates Suspect cancer agents V N.D. 2,3,7,8-Tetrachlorodibenzop-Dioxin (TCDD) (1746-01-6) Suspect cancer agent Teratogen - 0.5 REMS During Pregnancy 5 REMS-Equiv./yr. (NCRP Report 39, 1971) (R) 200 pg/nu 600 pg/ni C* No skin contact (UCC) No exposure* (UCC) Tetramethylurea (632-22-4) N.D. Teratogen No exposure* (UCC) Toluene-2,4diamine (95-80-7) Suspect cancer agent N.D. 0.1 ppm* No skin or oral contact Footnote: (A) Standard based on suspected presence of Polycyclic Aromatic Hydrocarbons (R) Revision from previous list U.C. Corporate HERB {Approved 1 March 1982) UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST (See Reverse Side) ' NOTES OF EXPLANATION: 1. A material Is included on this list following a detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed. New entries are made, or existing ones modified, when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*) are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will reviewed at the earliest convenient time. (b) Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D." indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for which there is insufficient evidence that the substance causes cancer in man. 3. Teratogen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation. U. C. Corporate HERB Accepted: 1 March 1982 BRB 0512 Page of 14 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST BASED ON CARCINOGENICITY., TERATOGENICITY OR OTHER SIGNIFICANT TOXICITY (See Reverse Side for Explanations and Definitions) SUBSTANCE (CAS No.) CARCINOGENICITY TERATOGENICITY OTHER SIGNIFICANT TOXICITY . EXPOSURE STANDARD FOLLOWED BY UNION CARBIDE (SOURCE) Trichloro ethylene (79-01-6)' ** (-) 50 ppm (ACG1H) Vinyl Chloride (75-01-4) Known human carcinogen >A] 'V t Teratogen* - (UCC) _1 ppm 5 ppm/15 min C (OSHA) ! U.C. Corporate HERB (Approved 1 March 1982) BRB 0513 UNION CARBIDE INTERNAL EXPOSURE STANDARDS LIST " (See Reverse Side) ~ NOTES OF EXPLANATION: 1. A material is included on this list following s detailed evaluation of published toxicological, medical, epidemiological and other relevant information by the Union Carbide Corporate Toxicology Assessment and Advisory Committee (TAAC) and subsequent review and acceptance by the Corporate Health Effects Review Board (HERB). 2. This listing is periodically reviewed,. New entries are made* or existing ones modified,; when TAAC and HERB determine that there is sufficient credible evidence for such as action. 3. (a) The entries marked with an asterisk (*} are those which have not yet been formally reviewed and verified by TAAC as part of a current updating procedure. Those so marked will ^e reviewed at the earliest convenient time. <b> Entries marked with a double asterisk (**) indicate they are under continual review because of a current deficiency of relevant credible data. (c) "N.D.M indicates that information has not been located to allow a decision on carcinogenic or teratogenic potential. (d) The symbol (-) indicates that the available evidence is sufficient to determine that a material does not cause a given effect. DEFINITIONS: 1. Known Human Carcinogen means a substance for which there is sufficient credible evidence to determine that the material has caused cancer in humans. 2. Suspect Cancer Agent means a substance for which there is credible scientific evidence, based on animal and other related studies, that the material is carcinogenic in laboratory animals, but for whi:h there is insufficient evidence that the substance causes cancer in man. 3. Teratogen means a chemical substance or physical agent which causes abnormalities in structural and/or functional development during gestation. U. C. Corporate HERB Accepted: 1 March 1982 BRB 0514 INTERNAL CORRESPONDENCE UNION CARBIDE CORPORATION quo ridgebury road, danbury. ct 06B17 To(Namai Oivieton Location Area Gcgy to HOLDERS OF THE CORPORATE OCCUPATIONAL HEALTH MANUAL Da" Originating Oopt. May 28, 1982 Area Sutoject The attached UCC Internal Exposure Standards List is for inclusion in your Corporate Occupational Health Manual. The list is essentially the same as I transmitted on Feb ruary 9, 1982, with some changes made based on feedback received from you... Changes from the February list are noted with an "R". Please address any questions regarding the list to Norm Gaines. The Health Effect Review Board is sponsoring a review of the issues surrounding this list - its purpose, uses, and contents. Representatives from the GOHC are partici pating in this review, and you will be kept advised of its progress. Very truly yours. AGV/pob A. G. Voress -- BRB 0486