Document o9wBdzRJm9k6pd2aDJ2oe41Bo
*JC IV. -i 2
INTERNAL CORRESPONDENCE
^CHSMICAiS AND PLA5T3CS .
RECEIVED JUL 2/, 197G . T. W. CARMODY
270 PARK AVENUE, NEW YORK, NEW YORK 10Q17
to {Name) cc:
Operations Managers Market Area Managers Plant Managers R&D Directors Engineering Directors Distribution Directors
Attached Distribution List
Oat, July 18, 1978
Originating Dept. SHAKE - EP/OH
Floor Numbtr
21
Answering tetter date
subject
Updated C&P List of Fotential Carcinogens
Attached is the up-to-date list of substances of interest to C&P which we have determined should be regarded as potential carcinogens and therefore handled accordingly. This replaces the previous list issued with our letter dated January 31, 1978. Several additions have been made, including certain chromium compounds and epoxy resins.
Permissible exposure limits and other information regarding these substances are contained in a separate detail document which will be sent to all Industrial Hygiene and Medical Depart ments, environmental protection and occupational health coordi nators, technology managers, and other appropriate managers for all locations and functions. Others with a need to know may obtain.a copy by contacting Dr. W. C. Kuryla, Technology ManagerOccupational Health, at the South Charleston Technical Center.
Medical Director Chemicals and Plastics
EQH/AEM/ad Attachment
9443
Operations Manager Environmental Protection and Occupational Health Chemicals and Plastics
ucc 100336
Additional Distribution
*C. R. Allenbach Niag. Falls(Metals)
*R. C. Andrews
322 (H&A)
L.. M. Eaker
19
*F. D. Bess
511
*N. E. Bolton
4
*J. B. Browning 22
*T. J. Burke
781 (BP)
*T. W. Carmody^"" 22
*C. P. Carpenter Mellon
R. G. Chenoweth 511
*R. J. Conkling 323(Linde)
*E. F. Cox
Mellon
*L. A. Crisorio 222
*J. M. Cwikla
358 (Film)
*C. U. Dernehl
4
J. M. Fallon
21
*J. A. Fitzgerald Jacksnvl.(APD)
*N. W. Gaines
511
*W. F. Gorham
312 (98)
*D. E. Gould
312(Somvl.)
*R. E. Graebert 511
*R. A. Hardison Parma(CPD)
*H. L. Haynes
22
*D. L. Heywood
21
*E. R. Homan
Mellon
*J. C. Hovious
511
*R. A. Howard
44 (Elec*)
*E. Q. Hull
511
*R. F. Jensen
323 (Linde)
*J. B. Johnson
511
*R. G. Jordan
OakRidge(Nuc.)
*R. T. Kramer
512
*W. C. Kuryla
511
*T. A. Lincoln
22
*M. G* Manetti
46
*J. D. Martin
510
*A. E. Montagna 21
*0. P. Mukheja
440(Toronto)
*R. E- Peele
511
*E. A. Piersall 250(Metals)
*T. P. Raby
312(51)
*J. A. Ring
19
C. D. Schmidt
29
T. N. Tackett
10
*A. G. Voress
21
*G. W.jWainwright 1200 (Geneva)
*C. S. Weil
Mellon
*J. W. Whittlesey 46
*R. C. Wise
21
*V. A. Yarborough 44(Devel.)
R. L. Yelton
29
N. L. Zutty
29
Additional detail document enclosed.
A. E. Montagna-7/18/78
UCC 100337
C&P OCCUPATIONAL HEALTH TEAM LISTING OP POTENTIAL CARCINOGENS
* JULY d. 1978
2-Ac etylaminofluorene
Acrylonitrile (a) (b)
U-Aminodiphenyl
Asbestos (a) (b)
Benzene (a) (b)
Benzidine
Benzidine-Derived Dyes
3is-2-chloroethyl ether (Dichloroethyl Ether: CHLOREX) (a )
3is-2-chloroethyl-2naphthylamine
Bis-chloromethyl ether
Carbon tetrachloride (a)
Chloroform (a)
Chloroprene
Chromates of Lead & Zinc
Chromium-6 Carcinogenic Compounds (including bis-Triphenyl Silyl Chromate)
3,3* -Dichlorobenzidine (and salts)
Diethyl sulfate (a)
Diisopropyl sulfate (b)
Dimethyl sulfate
Ethylene Thiourea
2-Nitropropane
4-Dimethylaminoazobenzene
Nitrosoamines (b)
1,4-Dioxane (a)
Epichlorohydrin (a)
Epoxy Resin ERL 2774 (a) (Dlglycidyl Ether of Bisphenol A)
Epoxy Resin ERL 4205 (a) (Bis (2,3-Epoxycyclopentyl) Ether)
Epoxy Resin ERL 4206 (Vinylcyclohexene dioxide) (a)
Epoxy Resin ERL 4234 3--(3',4' - Epoxycyclohexyl) 8,9-epoxy-2,4-dioxaspiro (55-unaecane) (a)
N-Nitrosodimethylamine (b)
Perchlorcethylene (a) (Tetrachloroethylene)
Polychlorinated Biphenols (b)
Polycyclic Aromatic Hydrocarbons (a) (b) (Fuel Oil Residues; Quench Oil, pitches; tars, Dripolenes, A, B, and C, Resin B Condensates)
B-Propiolactone
Toluene-2,4-diamine (a)
Ethylene dibrcmide
Trichloroethylene (a)
Ethylene dichloride (a)
Vinyl Chloride (a)
Ethyleneimine (Aziridine)
(b)
Methyl chloromethyl ether
a-Naphthylanine (b)
g-Naphthylamine
Neopentyl glycdl diacrylate (a)
Nickel, Inorganic (a)
4-Nitrodiphenyl
UCC 100338
(a) C&P Product, Raw Material, or Process Intermediates
(b) Pos: ible Contaminant in C&P products cr operations
V. C. Kuryla/gc
July 11, 1978
C/P OCCUPATIONAL HEALTH TEAM LISTING OF POTENTIAL CARCINOGENS
Page 1 of 6
SUBSTANCE 2-Acetylami nofluorene
CATEGORIES* CX
ACGIH UV
Acrylonitrile*** 4-&ninodiphenyl
A 20 ppin AX NE
Asbestos*** Benzene***
AX 5 fibers/cc > 5um long
AX 10 ppm
Benzidine
AX NE
Benzidine-Derived Dyes
C--
Bis-2-chloroethyl ether C 5 ppm (Dichloroethyl
Ether: CHLOREX)***
EXPOSURE LIMITS
NIOSH PROPOSAL OR OSHA STANDARD**
C/P STANDARD OR GUIDELINE
NE (c)
2 ppm (d) NE (c)
2 fibers/cc (c) > 5 ny/long 1 ppm (c)
NE (c)
--
NE; cf Regulation 29 CFR 1910.1014
2 ppm
NE; cf Regulation 29 CFR 1910.1011
2 f ibers/cc > 5 millong cf Regulation 29 CFR 1910.1001
1 ppm; NSOOC cf Regulation 29 CFR 1910.1028
NE; cf Regulation 29 CFR 1910.1010
NE (Hull, 4/12/78)
0.1 ppm
UCC 100339
*
A = Known.Human Carcinogen D = Suspected Human Carcinogen C = Experimental (Animal) Carcinogen AX = Known Human Carcinogen - Regulated
by Government BX = Suspected Human Carcinogen -
Regulated by Government CX => Experimental (Animal) Carcinogen -
Regulated by Government
urv n .1 7 ft
***
C and P Product, Raw Material
or Process Intermediate
**
a = NIOSH Criteria Document b = NIOSH Alert c OSHA Permanent Standard d = OSHA Emergency Temporary Standard****
**** Possible contaminant In C and P products or processes
HSDOC = Ho skin or oral contact NE = No exposure or contact by any route
SUBSTANCE
B1s-2-chloroethyl-2naphthylamine
Bis-chloromethyl ether
Carbon tetrachloride***
Chloroform***
Chloroprene
Chromates of Lead and Zinc (as Cr)
Chromium-6 Carcinogenic Compounds (Including Bis-Triphenyl Silyl Chromate***)
3-3'-Diehlorobenzidine (and salts)
Diethyl sulfate***
C/P qccupatiowIp health team LISTING OF POTENTIAL CARCINOGENS
Page 2 of 6
EX P 0 SURE LI HITS
CATEGORIES*
ACGIH TLV
NIOSH PROPOSAL OR OSHA STANDARD**
C/P STANDARD OR GUIDELINE
A NE
AX 1 ppb
NE (c)
NE; cf Regulation 29 CFR 1910.1008
C 10 ppm
2 ppm (b) 10 ppm (c) 2 ppm
C 10 ppm
2 ppm (a) 50 ppm (c)
2 ppm
B 25 ppm
1 ppm (b) 25 ppm (c)
1 ppm
B 0.05 mq/m3 (as Cr)
_----
0.05 mq/m3 (as Cr)
B --
1 ug/m3
1 >ig/m3
CX
NE (c)
NE; cf Regulation 29 CFR
1910.1007
C 1 ppm; NSOOC
UCC 100340
*
A = Known Human Carcinogen B = Suspected Human Carcinogen C = Experimental (Animal) Carcinogen AX =* Known Human Carcinogen - Regulated
by Government BX = Suspected Human Carcinogen -
Regulated by Government CX = Experimental (Animal) Carcinogen -
Regulated by Government
i.irkr/7-l-7fl
irk
C and P Product, Raw Material
or Process Intermediate
$rk
a = NIOSH Criteria Document b = NIOSH Alert c = 0SI1A Permanent Standard d = OSHA Emergency Temporary Standard****
**** Possible contaminant in C and P products or processes
NSOOC = No skin or oral contact.
~
NE = No exposure or contact by any route
C/P OCCUPATIONAL HEALTH TEAM LISTING OF POTENTIAL CARCINOGENS
Page 3 of 6
SUBSTANCE
Diisopropyl sulfate**** Dimethyl sulfate 4-Dimethyl ami noazo
benzene 1,4-Dioxane***
CATEGORIES*
ACGIH TLV
C
c 1 ppm cx
C 50 ppm
Epichlorohydrin***
Epoxy Resin ERL 2774*** (Diglycidyl Ether of Bisphenol A; 2,2Bis(p -Glycidyloxyphenyljpropane)
Epoxy Resin ERL 4205*** (Bis(2,3-Epoxycyclopentyl)Ether)
C 5 ppm C
C
EX P 0 S UR L I'M IT S
NIOSH PROPOSAL OR OSHA STANDARD**
C/P STANDARD OR GUIDELINE
NE (c) 1 ppm (a) 2 mg/m^ (a) 5 ppm {c)
1 ppm; NSOOC
1 ppm; NSOOC
NE; cf Regulation 29 CFR 1910.1015
cf letter Hull/Montagna, 12/16/77
0.5 ppm
To be determined, NSOOC
To be determined, NSOOC
UCC 100341
A = Known Human Carcinogen B = Suspected Human Carcinogen C = Experimental (Animal) Carcinogen AX = Known Human Carcinogen - Regulated
by Government BX = Suspected Human Carcinogen -
Regulated by Government CX = Experimental (Animal) Carcinogen -
Regulated by Government
WCK/7-1-78
irk k f
C and P Product, Raw Material
or Process Intermediate
irk
a = NIOSH Criteria Document b = NIOSH Alert c = OSHA Permanent Standard d =* OSHA Emergency Temporary Standard
**** Possible contaminant In C and P products or processes
N50UC= No skin or oral contact NE = No exposure or contact by any route
C/P OCCUPATlft. HEALTH TEAM
SUBSTANCE
LI STIMG OF POTENTIAL CARCINOGENS
Page 4 of 6
EXPOSURE LIMITS
CATEGORIES*
ACGIH TLV
NIOSH PROPOSAL OR OSHA STANDARD**
C/P STANDARD OR GUIDELINE
Epoxy Resin ERL 4206*** (Vinyl cyclohexene dioxide)
Epoxy Resin ERL 4234*** 3-(3*,4'-Epoxycyclohexyl)8,9-epoxy-2, 4-dioxaspiro(5,5undecane)
Ethylene dibromide
Ethylene dichloride***
Ethyleneimlne**** (Azirldine)
Ethylene Thiourea
Methyl chloromethyl ether
Ct-N a ph t hy1amine ** **
C 10 ppra
C
C 20 ppm C 50 ppm CX C AX BX
1 mg/m3 (a) 5 ppm (a) NE (c)
--
NE (c)
NE (c)
10 ppm; NSOOC
1 ppm; NSOOC
0.1 ppm 5 ppm NE; cf Regulation 29 CFR
1910.1012 NE (Hull, 4/12/78} NE; cf Regulation 29 CFR
1910.1006 NE; cf Regulation 29 CFR
1910.1004
A = Known Human Carcinogen B =* Suspected Human Carcinogen C = Experimental (Animal) Carcinogen AX = Known Human Carcinogen - Regulated
by Government BX = Suspected Human Carcinogen -
Regulated by Government CX = Experimental (Animal) Carcinogen -
Regulated by Government
i ***
C and P Product, Raw Material
or Process Intermediate
** a = NIOSH Criteria Document b NIOSH Alert c = OSHA Permanent Standard d = OSHA Emergency Temporary Standard
**** Possible contaminant in C and P products or processes
NS00(T= No skin or oral contact NE = No exposure or contact by any route
U C C 100342
C/P OCCUPATIONAL HEALTH TEAM LISTING OF POTENTIAL CARCINOGENS
Page 5 of 6
SUBSTANCE
9-Naphthylamine
Neopentyl glycol*** diacrylate
Nickel, Inorganic***
4-Nitrodiphenyl
CATEGORIES*
ACGIH TLV
AX NE
C
B
AX NE
2-N1tropropane Nitrosoamines**** N-N1trosod tmethylamine
****
Perchloroethylene*** (Tetrachloroethylene)
C 25 ppm C CX
C 100 ppm
EXPOSURE LI HITS
NIOSH PROPOSAL OR OSHA STANDARD**
C/P STANDARD OR GUIDELINE
NE (c)
NE; cf Regulation 29 CFR 1910.1009
NSOOC
15>ig/m3 (a); 1 mg/mJ (c)
NE (c)
1 mg/m3; cf 29 CFR 1910.93
NE; cf Regulation 29 CFR 1910.1003
NE (b)
NE (c) 50 ppm (a)
100 ppm (c)
1 ppm; Peele Letter 6-30-77
NSOOC
NE; cf Regulation 29 CFR 1910.1016
50 ppm
U C C 100343
*
A - Known Human Carcinogen B = Suspected Human Carcinogen C = Experimental (Animal) Carcinogen AX = Known Human Carcinogen - Regulated
by Government BX = Suspected Human Carcinogen -
Regulated by Government CX = Experimental (Animal) Carcinogen -
Regulated by Government
i inf n i ?n
***
C and P Product, Raw Material
or Process Intermediate
**
a => NIOSH Criteria Document b = NIOSH Alert c = OSHA Permanent Standard d = OSHA Emergency Temporary Standard
Tkk* possible contaminant in C and P products or processes
NSOUC = No"skin or oral contact NE = No exposure or contact by any route
C/P OCCUPATI^L HEALTH TEAM
LISTING OF POTENTIAL CARCINOGENS
Page 6 of 6
SUBSTANCE
Polychlorinated Bi
phenyls
****
j9~Propio lactone
CATEGORIES*
ACGIH TLV
B, C CX
1 mg/m^
42% Cl 0.5 mg/m^
54% Cl
Polycyclic Aromatic*** Hydrocarbons (Fuel Oil Residues; Quench Oil, pitches, tars, Dripolenes A, B, and C. Resin B Condensates)
Toluene-2,4-diamine***
Trich1oroethylene***
A 200 ^g/rn^
C C 100 ppm
Vinyl chloride***
AX
EX Pfl'S UR E LIMITS
NIOSH PROPOSAL OR OSHA STANDARD**
C/P STANDARD OR GUIDELINE
ljjg/m3 (b);
0.5 mg/m^ (c) 54% Cl
NE (c)
1 ug/m3
NE; cf Regulation 29 CFR 1910.1013
cf letters Hull/Guest, 3/3/75 Hull/Montagna, 10/76 Hu 11/Montagna, 12/21/77
'NSOOC
100 ppm TWA (a); 100 ppm 8 hr TWA (c)
1 ppm (c)
0.1 ppm; NSOOC (Olln) 25 ppra (Hu11/Montagna, 3/11/78)
1 ppm; cf Regulation 29 CFR 1910.1017
U C C 100344
*
A = Known Human Carcinogen B * Suspected Human Carcinogen C = Experimental (Animal) Carcinogen AX => Known Human Carcinogen - Regulated
by Government ' BX = Suspected Human Carcinogen -
Regulated by Government CX = Experimental (Animal) Carcinogen -
Regulated by Government
urv n 1 70
***
C and P Product, Raw Material
or Process Intermediate
**
a = NIOSH Criteria Document b = NIOSH Alert c = OSHA Permanent Standard d = OSHA Emergency Temporary Standard
**** Possible contaminant In C and P products or processes
NSU(J(J"= No skln or oral contact NE = No exposure or contact by any route