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REPORT OJS, TH$ ^ACTIVITIES OF, THE LABORATORY OF
APPLIED PHYSIOLOGY -- 192Q-1S21
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In December, 1920, Dr. C. K.. Reiman, who had been doing the
chemical work of the laboratory, accepted a research position
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With Arthur D. Little, Inp. Hip place was taken in February
by ISt . Philip Drinker. In connection with, the new. load work
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Dra. J. C. Aub, J; A;'Key, and L. T. Pairhall entered the
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laboratory staff. As' voluntary workers or research .-assist ant a
with and without salary, the laboratory has had the services
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of the fol lowing (Iruvinp--.the'-oast; :yesr: .
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Francis 17. Peabody ,!AM.:Dv .
Herrmann 1.1 .Blumgart, AUD.
'Seth M* "Fitchet, M. p.
,-^alker . ' Katherine- d. nr inker, M.i).
Henry 3. Forbes, M.D. .
'iHenryf...
. Sana H. Tomplcins,.
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itb.search /Activities ,
1. Dr. 0. A. Drinker, i/a*. L. A. Shaw, Dr. ii. P. Oarr, Dr. K. .H. Drinker, and.- iiisp-.HSdftpyirA-.Tompkins -.continued studies upon the in it i;al- distribution and rates of migration of* different insoluble particulate- - compounds' of - manganese, the ultimate aim being to determine-', how - far the physical and chemical characteristics of these compounds could be correlated with their behaviour in the apimal. ASuch information
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is essential to the understanding and prevention ;,of harm
done by different dusts. '
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S. Dr. C. K.: nr inker and i)r ; K. R. Drinker extended and
finished a series of studies begun in 1915 upon the circulation
in bones.
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5, Dr, C , K. hr i nker, nr. franc i s, W. Pe abo cl y and Dr..... Herrmann Blumgart organized ami carried through experiments
to show the effect .of increasing the blood in tho lung, upon
the air space, These experiments thro1..' much light; on one"y -
cause of the reduction' in vital capacity which is observed
in certain heart'cases.
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4. Dr-Wallace 0. Penn continued his work" on. the .
reactions of leucocytes-isolated from the peritoneal cavity of the rat upon differentytypes of particulate material.- '- ' 1.
He has demonstrated quite positively that carbon particles
are ingested from three to four times as readily as those
of silica, and has thus, suggested .the. first step in our '-v. '': : . t `
understanding of the action of these substances in. failing : ;y
to produce or producing pulmonary' fibrosis. . Dr. fenh has
recently- extended these studies to phagocytes secured
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directly from the 'lung. .
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5. ilr . Philip-'Drinkrelrgand l5r..--H-b'b:ert 11. . Thomson, as;
the first part of work upon brass poisoning, have devised new.
apparatus for determining the partiqulateycontent of air.;* .. & Dr. H. B. Porbes., , in collaboration with. Dr . ptanlG-y.
Cobb of the Department of' Heurop.ath.plogy, ..has experiments, in
progress upon the effects -of":jigon cerebro- so
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spinal fluid pressure with especial1referonoe^to the develop ment of headachee.
Teaching
The usual course in Applied. "biysiblogy was given to such Industrial;'Hygiene students. '.appeared. : In- the soring a new andmuch `broader course v/ae `pro jested . This has proved attractive to fourth-Year medical' students, zu men having elected it.for the current year. 'Three students were given special work in air and dust analysis by Hr. Philip hr inker.
hr. 0. . urinker.-IdP*. W*' 6. vVnn, - and Mr. L. A. Shaw have assisted actively in the teaching of the First-Year students in Physiology, the first hy giving certain lectures, the last two by supervisingthe Mammalian 'experiments; and giving; the demonstrations. '
Special Project's
The laboratory has continued former favor able relations ,'t- - j-
with the hew, Jersey line Co my; any hand -.superviaps the yjrcventive
work on manganese poisoning carried out by the company;. The. ;
work of Mr.. Philip Drinker on^ Brass. Poisoning i s financed,
by a grant of $5000 from,;this company.
The Leach Institute has contributed #51,000 for broad
studies uoon beau 'Poisoning.> This woru is. under the general
supervision of Jr. J. 0. Aub and.a group of associates
consisting of Drs. Fairh
Mias Minot Mrs. Frank
furter, and Mies Smith. i>r. --4rthur; B. iamb" ' irf th'e chemical
staff in Cambridge is also in co-operation, While this
work began officially during the past summer and will not -
be reported . uoon for another ;;car, gratifying? results in the
development- of a "method f or lead analysis ha*ro already been-
obtained.
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October, 24, 1921..
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