Document o9oa5y2bRm03169xoXB9ObgxE

REPORT OJS, TH$ ^ACTIVITIES OF, THE LABORATORY OF APPLIED PHYSIOLOGY -- 192Q-1S21 ' ...v 7 , _' ; ` Changes in -',y v': .'' : .phyA A Av Personnel . 7-/-,-A. .A ' *.' . A 7 '`'AAA- - ' ' p \A' kV"'y'"Ah ?.'* ' In December, 1920, Dr. C. K.. Reiman, who had been doing the chemical work of the laboratory, accepted a research position ; - -A' Vp A'A'Aa 'fr'' '/\yAy-;'Q::.A' .v mVV- ..) A. With Arthur D. Little, Inp. Hip place was taken in February by ISt . Philip Drinker. In connection with, the new. load work ;; , y y 1 7. V ' . /A:-V"l?jAA'l'AAovy'yC-yA l>iiyhA-/;;./ 7y ; ,>. '! *' Ar --"-vAy- - Dra. J. C. Aub, J; A;'Key, and L. T. Pairhall entered the . laboratory staff. As' voluntary workers or research .-assist ant a with and without salary, the laboratory has had the services ... A- A- AA'A'-Ay 7 ;. A. -Ay.. of the fol lowing (Iruvinp--.the'-oast; :yesr: . -. ,77 Francis 17. Peabody ,!AM.:Dv . Herrmann 1.1 .Blumgart, AUD. 'Seth M* "Fitchet, M. p. ,-^alker . ' Katherine- d. nr inker, M.i). Henry 3. Forbes, M.D. . 'iHenryf... . Sana H. Tomplcins,. .. AA. :7711'/ :; "A y 7. itb.search /Activities , 1. Dr. 0. A. Drinker, i/a*. L. A. Shaw, Dr. ii. P. Oarr, Dr. K. .H. Drinker, and.- iiisp-.HSdftpyirA-.Tompkins -.continued studies upon the in it i;al- distribution and rates of migration of* different insoluble particulate- - compounds' of - manganese, the ultimate aim being to determine-', how - far the physical and chemical characteristics of these compounds could be correlated with their behaviour in the apimal. ASuch information lu C- MA u- 1720 is essential to the understanding and prevention ;,of harm done by different dusts. ' 'v- S. Dr. C. K.: nr inker and i)r ; K. R. Drinker extended and finished a series of studies begun in 1915 upon the circulation in bones. y, 1>'"; .fy' . t"! 5, Dr, C , K. hr i nker, nr. franc i s, W. Pe abo cl y and Dr..... Herrmann Blumgart organized ami carried through experiments to show the effect .of increasing the blood in tho lung, upon the air space, These experiments thro1..' much light; on one"y - cause of the reduction' in vital capacity which is observed in certain heart'cases. *. . ' 4. Dr-Wallace 0. Penn continued his work" on. the . reactions of leucocytes-isolated from the peritoneal cavity of the rat upon differentytypes of particulate material.- '- ' 1. He has demonstrated quite positively that carbon particles are ingested from three to four times as readily as those of silica, and has thus, suggested .the. first step in our '-v. '': : . t ` understanding of the action of these substances in. failing : ;y to produce or producing pulmonary' fibrosis. . Dr. fenh has recently- extended these studies to phagocytes secured \ ' directly from the 'lung. . y - .. 5. ilr . Philip-'Drinkrelrgand l5r..--H-b'b:ert 11. . Thomson, as; the first part of work upon brass poisoning, have devised new. apparatus for determining the partiqulateycontent of air.;* .. & Dr. H. B. Porbes., , in collaboration with. Dr . ptanlG-y. Cobb of the Department of' Heurop.ath.plogy, ..has experiments, in progress upon the effects -of":jigon cerebro- so MU?<y> spinal fluid pressure with especial1referonoe^to the develop ment of headachee. Teaching The usual course in Applied. "biysiblogy was given to such Industrial;'Hygiene students. '.appeared. : In- the soring a new andmuch `broader course v/ae `pro jested . This has proved attractive to fourth-Year medical' students, zu men having elected it.for the current year. 'Three students were given special work in air and dust analysis by Hr. Philip hr inker. hr. 0. . urinker.-IdP*. W*' 6. vVnn, - and Mr. L. A. Shaw have assisted actively in the teaching of the First-Year students in Physiology, the first hy giving certain lectures, the last two by supervisingthe Mammalian 'experiments; and giving; the demonstrations. ' Special Project's The laboratory has continued former favor able relations ,'t- - j- with the hew, Jersey line Co my; any hand -.superviaps the yjrcventive work on manganese poisoning carried out by the company;. The. ; work of Mr.. Philip Drinker on^ Brass. Poisoning i s financed, by a grant of $5000 from,;this company. The Leach Institute has contributed #51,000 for broad studies uoon beau 'Poisoning.> This woru is. under the general supervision of Jr. J. 0. Aub and.a group of associates consisting of Drs. Fairh Mias Minot Mrs. Frank furter, and Mies Smith. i>r. --4rthur; B. iamb" ' irf th'e chemical staff in Cambridge is also in co-operation, While this work began officially during the past summer and will not - be reported . uoon for another ;;car, gratifying? results in the development- of a "method f or lead analysis ha*ro already been- obtained. ,.' October, 24, 1921.. rQ vM. r$3y : ^ - CV'V* ; `o v ' :