Document o9XnBQV98dw465aJ1XDZwNeMg
FILE NAME: CTFA (CTFA) DATE: 1973 July 31 DOC#: CTFA002 DOCUMENT DESCRIPTION: Unpublished Internal Reports w ith Cover Memo
MORANDUM
DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
PUBLIC HEALTH SERVICE
_ .
FOOD AND DRUG ADMINISTRATION
I V^
; Dr. Robert M. Schaffner, Director Office of Technology (BF-400)
1973
>M : Dr. Alfred Weissler, Acting Director Division of Color Technology (BF-430)
IJECT: Summary and Comments on Prof. Lewin's Analytical Results for Asbestos in Talc
1. The purposes of this memorandum are to present a summary of the analytical results for asbestos in Cosmetic talcum-type powders obtained
by Prof. Seymour Z. Lewin of New York University in his role of consult
ant to FDA; to compare his results with those obtained by other labora tories on some of the same samples; and to make some comments on the gen eral question of suitable techniques for the analysis of asbestos in talc.
2. 1 asked Dr. Lewin in December 1971 to undertake asbestos analyses in 100 samples of cosmetic powders; the scope was expanded on two subsequent occasions, to include a total of 195 samples. I chose Dr. Lewin for this work because he is an internationally-recognized expert on mineralogical chemistry and because he is a member of the academic community and there fore likely to be impartial in a confrontation between industry and government. Furthermore, his competence had previously been recognized by industry (by virtue of their own use of him as a consultant) which appeared to confer a desirable immunity against possible industry attacks on the validity of the results.
3. Dr. Lewin's findings are shown in Table I; the key to the identities of the numbered samples is given in Table IV. Please note also the ex planatory comments in Dr. Lewin*s memo of July 10, 1973, which is an Attachment to Table I. No varieties of asbestos other than chrysotile (a serpentine) or tremolite (an amphibole) were found by Dr. Lewin in the 195 samples which he examined. As shown in Table I, Dr. Lewin found definite indications of chrysotile in 17 of the samples (many of these also had tremolite) and definite indications of tremolite but not chryso tile in an additional 18 of the samples. These results were obtained primarily by means of X-Ray diffraction, supplemented in some cases by optical microscopy and other techniques. However, Dr. Lewin points out on page 2, paragraph 1 of the Table I Attachment that the chrysotile he has identified in commercial products shows several significant dif ferences from "classical" chrysotile: in the location of its X-Ray dif fraction peaks, in its appearance under the microscope, in its reactivity toward dilute acid, and in its behavior with respect to differential thermal analysis.
HHS00000197
Page 2 - Dr. Robert M. Schaffner
4. In Table II, I have compared Dr. Lewin's results for tremolite with
those obtained for some of the same samples at FDA. (by means of optical
m(ibcyromsecaonpsy)ofaXn-dRaaty
the Pfizer Minerals, Pigments, and Metals diffraction). This comparison, which was
Division undertaken
in order to obtain additional information on the samples, shows good
semi-quantitative agreement among the three laboratories. Whatever
quantitative differences exist in the amounts of tremolite found can be
understood readily on the basis of such factors as (a) preferred orien
tation of plates and fibers in the packing of the X-Ray diffraction
sample, and (b) inhomogeneities in sample composition, caused for example
by air lutriation within the container when it is shaken.
5. In Table III, I have compared Dr. Lewin's results for chrysotile with those obtained for some of the same samples by four other labora tories; the additional two laboratories included in this part of the study are Columbia Scientific Industries of Austin, Texas (who sell the Stone apparatus for differential thermal analysis) and the Health Protection Branch of the Department of National Health and Welfare of the Canadian government in Ottawa. The agreement of results from dif ferent laboratories is much less satisfactory for chrysotile than that discussed above for tremolite. For example, samples 8S and 163 were found by Dr. Lewin to contain 57 and 107 of chrysotile, respectively, but chrysotile was not found in these samples by the other laboratories. Also, a preliminary finding of chrysotile in a sample of Johnson and Johnson Shower to Shower Body Powder has been disputed by the company, which claimed that their own analyses by several different techniques fail to show the presence of chrysotile. The explanation for these differences is attributable largely to Dr. Lewin's inclusion in the term "chrysotile" of mineral species which show significant differences from classical chrysotile, as discussed in paragraph 3 above.
6. The difficulties involved in analyzing talc and other samples for small amounts of asbestos have been pointed out by many investigators. It is not surprising that the results of different laboratories disagree sometimes, especially in the presence of transitional or altered minera logies! species. Moreover, with regard to the two varieties of asbestos of concern here, it is unfortunate that the one which is a clear inhala tion hazard to man, namely chrysotile, poses an intrinsically more dif ficult analytical problem than the other, tremolite, which has not yet been shown to present a biological hazard. This is due in part to the less prominent X-ray diffraction peaks of chrysotile and to the fact that the fibers are often too small to be seen in the optical microscope.
7. In connection with a proposed new regulation on the safety of cos metic talcum powders, we face the problem of specifying an analytical test for asbestos which must be satisfied by the powders if they are not to be considerated adulterated. On the basis of information available at present, I recommend consideration of the following procedure. The powders shall be examined first by X-ray diffraction, which has a sensi tivity of the order of 17. for chrysotile and somewhat greater sensitivity
HHS00000198
Page 3 - Dr. Robert M. Schaffner
for tremolite. If either species is found, confirmation that the species is present in fiber form is to be obtained by optical microscopy and elec tron microscopy. This is necessary because tremolite is known to occur in a non-fibrous fora, and the X-ray diffraction pattern of chrysotile is the same as that of antigorite, a non-fibrous form of the same min eral. The sample is considered adulterated if the presence of fibrous tremolite or chrysotile is shown by the above procedure. An alternative procedure^ based solely on optical microscopy (which is a less expensive and more widely available technique) might be proposed. However, the difficulty with optical microscopy alone is that it may completely miss the presence of chrysotile if the fibers are submicroscopiCj which may well be the case in finely-milled talc; X-ray diffraction is not subject to this source of error.
Enclosures
Alfped Weissler, Ph. D.
I HHS00000199
FINAL H8P0BT
XoRA PCWDSR DIFFRACTION ANALYSES OF COMMERCIAL COSMETIC POWDERS
Phlogo Saiool Tale Chlorite ni fee
1
2
3 4 .5
6
7
8
9 I II
12
13 14 15 16
70$ ' 100$
99$ 100$
95$ 8o$ 86$
95$ 89$
93$ 90$ 100$ 6o$
31$ 100$
es>ca
` 3$ node node nodo
2$ 2$ 7$ 2$ 7$ 3$ 2$ Ho do nodo 50$ n cdo
7$
nodo 1$ Ho do
3$ 5$ 2$
3$ 2$ 2$ 2$ nod
ndo .2$
nod CK
17
6o$
18
90$
19
97$
20 3 5 $ ;
21
67$
22
59$
23
42$
24
94$
25
95$
26
95$
27
78$
28 ca20$
30$ 4$ '1 $ 6o$
25$ 35$ 50$
1$ 2$ 1$ ned 1$
4$ 2$ 2$ 1$ 2$ 1$ 2$ 2$
3$ 4$ 2$ nodo
29 oa*94$ ` nodo
2$
30
97$
1$
2$
31
47$ 50$
2$
32
C0$ - 7$
3$
a= Quarts
n od 0 ndo nodo nod n 0do nd0
3$ nod,
2$ 2$ 4$ Ho do. nod, 10$ ndo no
Bolo mite
Ho d ned nod. Ho do Ho do nodo
2$ nod. nodo Rodo
2$ nodo no do
7$ nodo
utod o 2$ nodo
4$ 3$ Ho do
3$ 3$ nodo n cdo nod ndo
6$ 2$ Ho do Rode
3$ 5$ 3$ nodo Rod ned, 20$ nodo
Hado. Ho do
3$ 2$
2$' Rodo
8$ 8$
TramCalelte elite
Rodo Ho do no do nodo n,do nodo n 0do n 9d 0 Ho do n edo hod Ho do Ho do Ho d o Rodo <=?CP
nd,> De da nd Ho do n.de ndo rud0 n fldo nade nodo nda Ho do Roda Hj do Rad C3CP
Ho da Ho do Rodo n,d0 Ho do Ho da Rodo Red Rodo n,,dv Ho do 10$
Rada Rddo Rodo Ho da Roda Redo Hi do nido* Rda Ho n d t n^d
Ho do Hado Rede nd0
Ride' Redo Rodo mdo
Chryso= tile
ned Ho do Ho do ndo nd0 nodo
? Ho d Ho do Ho d<x n,do Hado nodo n ado n cdo * =p<=>
n ado n.d Rodo Rodo Rodo Hod*
? Ho do
? ? Ro do Rodo
nodo Rodo nd0 Ho do
Other Sneoies
Calndeeyl
ZnUndeeyl Kaolin,
Stareh
Kaolin* Mica
Kaolin
HHS00000200
Fsg# a
Phlogo= amole Tale Ghlorite ite
33
55$ 40$
2$
nodo
34
78$
35
78$
36 ea08i$
7$
4$'
5$ 2$
4$
Ho da
3$ 10$ nodo
37
38$
50$
5$
nodo
38
87$
5$
4$
2$
39
94$
3$
Hodo
3$
40
67$ 25$
nd<
3$
41
33$
8$
2$
2$
42
89$
6$.
n Dd 0 nodo
43
97$ Rado
n 9do
3$
44
*<=&
=>e
<==>
45
66$
30$
od Red,
4'i
48$
4o$
47
98$
Rodo
nodo nda
5$ nodo
43
88$
4$
2$
2$
49
too$
ndo
nde. Rodo
50
95$
5$
n<>d. Ha do
51
100$
Redo
Ho da ndo
52
87$
8$
53
90$
4$
2$
3$
2$
2$
54 .ca,,87$
55
8o$
56
90$
57
80$
58
96$
3$ 15$
7$ 15$ zi do
4$ Ha do ndo n 0do nodo
n<>d0 5$ 3$
Ro do 4$
59 ca<,90$
6o oaa6o$
61
38$
62
85$
63
87$
64 oa80$ 65 ca<,78$
66
84$
Ho do 30$ 40$
2$ 2$ 5$ 15$ 5$
Ila do ned n ado
3$ Hodo
4$
Ho do
3$
2$ 4$
3$ tid D
2$ Rodo
3$ - 3$
Belo* mite 3$ 8$ 5$ Rodo 7$ 2$ ndo 5$ 5$ 3$ Ha do
ecs
4$ 7$ Rodo 4$ n do Roda Ho da Ho do 2$ 4$ Rodo Rodo 5$ Ho do Rodo 7$ 18$ Rodo Rodo 3$ 4$ 3$
67
78$
15$
68
80$
15$
69
97$
1$
nd. Had? Ho da
Rodo n.do nod.
5$ 5$ Ho do
Saleite Rodo Rodo n Qdo Rodo Rodo Rodo Rodo nodo Rodo 2$ He dia -- ndo n 0do 2$ Rodo Rodo Rodo Rodo nodo nodo ndo nodo Rodo Roda Ho do Rodo 2$ Rodo 10$ Ho do nodo Rodo Rodo
Rodo nodo
2$
Tr*82IS= olite
Rodo Ho da n 0do nd Rodo ndc Rodo Rodo Rodo Ho do Rodo
(30
d Tld a H& do Rodo Roda Ha' d Rodo Roda Roda Rado Rode Rode Rdo Rodo Ad de Rdo He do Reda Rada
5$ Rado Roda Rode.
2$ Rodo Rado
Chryecsto tlle Rd0 node Ho do Rad Htrdo nodo Rodo Ho do Rodo Rodo Ho do
CCS
Rodo ned Ho do Rodo Rodo Ho do Roda Rado nodo
? He do Rodo Rado .nod* Rodo Rad Rodo Ho d. Ho do Roda Aodo A
2$ Ho da Ho di Rodo
'Ofcher Suede
Mloa
ZnO,Kaolln
Stereh ZnStear ZnStear. ZnStearo
HHS00000201
aansle Tal
TO 28#
71
85#
72
86#
73 ca8Q#
74
90#
75
75#
76
75#
77
91#
78
85#
79
81#
GO elio50#
81 esoSQ# 8a os,78#
83 oa084# 84 ea<*92# 85 ca086# 86 85#
87 a30# 88 61#
89
68#
90
55#
91 ca>50#
92
64#
93
55#
94 ea046#
-95 86#
96 28#
97
31#
98 a,40#
Ohlorlfes
60# 10#
5# 10# riodo
5# hod Hodo
2#
5# 40#
7# 12#. 6# 4#
5# 4# 50# n0d 1# nod0 1# iiodU 1# 4# nodo nod 1# ru do
Fhlge
.... sst
nodo n 0d,,
3# nodo nod Jlo cio
5# 4# 1# 4# io da 1# 2#
5# 2w co nod
2# nodo nod0
3# 3# nado rio do 4#
3# n.Q do
3# 1#
3#
=
Quarts
5# 2# 4#
3# n,,do
rio eia 5# 2# 4#
o d o 8# 6# 4#
nod. rio tdo nodo
4# 4#
5# 8#
7# n,,da
6# 6# 6#
5# 6#
5# ndo
99 e&o40# nodo
3#
n 0do
,00 eaa8o 10#
;oi
63# 8#
i02 63# 2#
^03 93# 3#
104 91# 3#
4#
3# Udo nodo
1#
rio dl<>
7# 3# n0do 2#
S1=
ralt#
7# rifio nodo
5# 5# 15# 10# ndo 3# 2# nodo 4#
3# 4# 3# G# 4# 12# 25# 10# 25# 3# 20# 25# 35# 4# 45# 35# 6#
6#
2# 4# 15# 4#
3#
C&leit
rudo n 0do
2# Rod,
5# 5# n do ned. Rodo 8# nodo rio do nodo n-o d o nodo nodo rijoda 3# XlirQo nodo 2# 5# n edo n cdo nodo Rad rio de*
h 0do 2#
2#
Rodo nodo Rodo n 0do rio do
o lite
n<jd0 3#
Rod nodo nodo nodo
5# 3# 5# nod nodo node ilo do nodo n,,do n<,do n edo Ho do 4# 5# 3# nado 5# 5# 4# 2# 8# 12# nodo
Ho da
n d<$ 15# 10# nod nodo
hrjrs O ther
tl
Sf3@les
Rado Rodo
Rodo Hoc0 ZnSte&ro
Rodo
Rado Redo
n,do Rodo
Rodo ?
? ?
?
?
?
?
?
5# 5#
5#
5#
Misa
5# ; 4#
? 3# s''' IO#
15# Rodo
n sdo
n od0 Ho do 7# >y Ho do Rodo
Kaolin* Miea
Kaolin, Misa
ZnSfcar0
HHS00000202
_ page 4
fhlg=> 53
asmi 3&c>. Chiarite i'fcSi Quarta
05 92# 37
i#
27
.06 91# 37
17 . 37
.07 87# 57
27
Ho do
.08 81# lo7
2 7
27
09 74# 15 7 3 7
37
10 99# n 0d c
%7 n<g do
li 42# 4o7
27 nodo
12 ea06o# zio do n o d o
47
13
75/ 157 n o d o
37
14 537 4o7 n o d o 37
15 537 4o7 n 9do 3 7
16 53# 4o7 n 0 do 3 7
17 427 357 n o d o 157
18 537 4o7 n 0do 3 7
19 497 4o7 n o d o
67
20 467 4o7 n o dso 87
21 877 87
27
n 0do
21 2 567 357 Ho d a 57
23 517 4o7 n o d o 37
.24 547 4 o 7 Ha d e 37
25 557 407
nodo
27
.26 757 io 7
37
47
.27 85 7 nd o Ho do* 47
.28 60 7 zio do rto d o He do
29 9 7 7 n o d o n o d o IXedo
30 a,,88# 77
Ho do
27
31 ea,,92
37
37 Ho do
32 957 37
27 ilo do
33 947 27
47 n 0do
.34 9 3 7 37
27 nodo
.35 ...93 7 27
37 n o d o
.36 897 4 7
37
27
37 9 1 7 4 7 n pdfl 3 7
38 857 7 7
37
27
39 ca.o857 n d o R a d o
27
,40 a0857 Ha d a n o d o
2 7
5L=> mite
2 7 27 67 37 37
n 0do
157
Ho do
17 47 47 4* 47 47 57 47 37 47
47
37 37 87
He do Ao do
37 37 27
ndo nodo
27 27 27 27 37
nodo
17
Caleit
nodo Ha d$ nodo ndo ndo nod0 Ha da
lo#
lift
nodo Rodo nodo
27 27
n 6do
17
Ha do
Rodo Rodo
nodo n ed 0
27
Hado Rodo Rod,
Ho do nodo Rodo
Rodo nodo Rodo
nodoRodo Ha do Rodo
Roda Rodo
Rodo ned nodo
n ado do Rodo Rodo
n<,d Rodo nodo Ho d-p Rodo nodo nodo nodo ndo Rodo nodo
nodo nodo ned Hoda Rodo nodo
trace
trace
nodo nodo Rodo nodo nodo nodo nodo . nodo
Rodo
Rodo
Shrys tbtr til
Rodo ndo Ho do nodo
? nodo nod,, Ho do
nodo Rodo
Ho Co nodo
? Roda Rodo
? Ho Co
? 9
Kaelln
Salloyllo Ae,Berle
?
7
nodo od nodo nod0
trace nodo nodo Rodo H a Co n do Rodo n cdo Ho do nodo
n d 0
Ba>rie Acic aWndeey,
ZaStear MgC2 ZiiStear, MgCJO^
HHS00000203
Samol Tale Chlorit
141
60# ziodo
142
79#
7#
143
55#
2#
144 ca70# lo#
145 ca<>70#
3#
146 ea,,85#
147 ca.65#
146 ca,45#
149 ca,50#
150
GO#
15% 63#
152 ca70#
153 eao80#
154 ca.70#
155 ca,84#
156 79#
157
63#
158
78#
159 ca074#
160
60#
161 59#
162
50#
163
55#
164 92#
165 92#
166 ca.50#
167
76#
168
Oto
169
OC
170
52#
171 70#
172 43#
173 oa.99# 174 ca060#
n.d. zi de 40# 10#
2# 25#
2#
2#
10# 10#
lo#
2# 7#
lo#
25# 25# 25#
2# 3# 5# 40# 10#
csrea
9 od0
lo#
50# ziodo
1#
- pag 5 f
oite Quarts
n,,dc
2#
5#
4#
Roda
3#
n.d.
6#
nodo nod
n<>.da nodo ndo mdo n.do n.do
nodo
4# nod nod. io#
5# 2#
rio d o
nodo
4# nd0
nod,
n.do
nodo
2#
h o do
zio d o
n0d.
nod.
2#
mdo nodo n,do
9
--
n.do n,,d. nod0 nodo
2#
Zio d<,
4# 4# 6# 3# 3#
frodo
n.d. 2# 2# 3#
n.do nod,
2#
Zia d o C3CJ
5# 5# nodo n.do 15#
D1 mit
1#
Calcite n.d.
Trni=> lite
n.d.
Chryso
tile
fledd
5# 25# nodo
nod. nodo node
Rod. 5# 5#
Zie de 10# " ?
3# n0d.
n.d. 2#
nod. n.do
8# 12# nodo lo#
nod
5# 5# zio do n.d. 5# ncdo n0dQ
no do n.do
2# 8# n.d. Zie de
zio d o
zie d a Rodo ned.
?
n.d. nedo
nodo
nodo
n.d,
Zie d o
zio d o
2# 2#
Zo d o n.do
3# 18#
n.do
n.d.
2#
10#
4# 10# `
4#
io#
4# 10#
5# 10#
20#
Rod,
2# n.d.
2# Zioda
8#
Zio d o
12# nodo
GPa
aa
C 9 0 1sa.80#
25# ndo
15# n.do 5# nodo
n.do nodo
ziod o
zio d o
2# n.d.
2# ,6#
Reda
n.ds
n.d.
n.dc
n.do 10# nodo n.d.
ilo d o
.2#
"S' es?
Rod.
Zio de 2#
nedo nad0
nod.
?
n.do
8#
Zia d e
? trace n.d.
Rodo
10# 1# ? ? n0do
caca
Oo
8# n<*d0 n0do
? n.d. `
Other Sueics ZnStear, Mgeo3
ZnStear. Kaolin ' ZnStear. Kaolin, ZnO ZnStear. Kaolin ZnStear. Kaolin Kaolin Fyrphyll
ite ZnO,Boric
Acid ZnO
Gypsum
Kaolin, Mica
HHS00000204
Sacrpie Tale OhXerite
175 Ga<> 86$
176 ea79$
177
84$
173 cao50$
179
97$
ISO 88$
181 cao70$
132 eao40$
183 cae76$ 184 93$ 185 ca,,50$ 186 eao50$
187 eao85$
18-S 70$
189 72$
190 ca082$
191 96$
192 100$
193 cao93$ 19^ ca*94$
195 97$
3$ 3$ 10$ 20$ n0do node n0d0
25$ 10$ 2$
8$
5$ 5$ 15$ 12$ 12$ 2$
n 0d*
2$ 2$
n 0do
Phlg==> T5t@ Quarfcs
n0d,, 2$ 4$ 2$
n.do ndo nodo
15$ nodo
nodo ndo n.d.
n 0do
2$
n 9d &
2$
ndo
n cdo nod. nodo n 0do
10$ 15$ 2$ 5$
3$ n0do ndo n0do nodo
2$ nd0 n.d
2$
3$
d,, 3$
ta
nd0
ndo
2$
Tic do n do
Dol Bit
nda n0d0 Hado 4$ Hado 12$ no do n,d
2$ nodo nodo nodo
no do
4$ 2$
3$ 2$
nodo
2$
3$ 3$
CaXeite
nodo n& d 0 nod n0de nodo na de 10$ lio do 10$ ndD 25$ 25$
5$ 5$ 5$
n 0do nodo nodo nodo
3$
tio dtp
Ohrys= Other lite tile ' Soesi&a
n9do nodo ndo
7
7
nodo
ndo
7
Kaoln
nsd
nod
nodo
nedo
nd4 nd0 Kaoln
n0d0 . 7
ZnO
1$
7
3$
n.d.
ndo ti do
2$ 1$
nado Zn
7
ZnO
n.d
7
i$
n0dfl
nodo
7
ndo n cdo
n.d n* do
mdo
7
ZnStear
nodo
7
nodo nod
HHS00000205
New York University Department of Chemistry 4 Washington Place, Room 410 NTeelwepYhoonrek:, (N21.Y2). 519080-033427
ATTACHMENT TO TABLE I
Memorandum to: Dr. George Thompson Food and Drug Administration
From:
S. Z. Lewin Chemistry Department, New York University
Re: Determination of Asbestos Contents of Commercial Talcum Powders.
This will serve to summarize the main points of our discussion on this date of July 10, 1973 with respect to the factors involved in the detection and estimation of asbestos in talc, and the status of the tabulation of results of the analyses of commercially avail able consumer products containing talcum powder.
My research group has been engaged in studies of talc and its accessory minerals continuously since July 1971, and we are continuing to work in this field. We have undertaken to investigate the follow ing problems:
A, Tabulation of the x-ray diffraction data for talc and all solid phases (whether naturally occurring, or added in the course of processing) encountered with talc in mineral, industrial, cosmetic and pharmaceutical products.
B. Elucidation of the x-ray diffraction spectrum (i.e., precise locations and relative intensities of peaks and variability thereof) of ehrysotile. Assignment of the diffraction peaks to the crystal planes responsible for them, and interpretation in terms of crystallogrE phy of the effects of grinding, orientation, and sample preparation.
C,, Investigation of the chemical properties of ehrysotile, antigorite, chlorite, tremolite, and talc; specifically, measurement of the rates of hydrolytic and ion replacement reactions.
D. Microscopy, both optical and electron, of ehrysotile and of talcs containing various accessory minerals, including ehrysotile and- tremolite.
E. Measurement of the degree of enrichment, due to air elutriation, of asbestos in the lightest fractions of the dust from commercial
HHS00000206
ffi 2. -
F,, Development of a method based on the combination of x-ray diffraction, chemical reactivity, and microscopy for the estimation of the chrysbtile and tremolite contents of consumer products (these two being the only asbestiforai minerals encountered in all the American products examined so.far, with only one possible exception), and application of the method to the analysis of about 200 standard store-purchased specimens.
G. Investigation of alternative analytical methods, viz., diff erential thermal analysis and density gradient centrifugation, as alternative or supportive techniques.
Our results to date support the following conclusions:
1. The ehrysotile that is found in commercial talcs is generally
different in significant respects from the ehrysotile that occurs as
massive, fibrous growths in veins in serpentine rocks. That is, the for
mer has diffraction peaks that may differ from the latter by as much as 0.2 A (at 7 .3 A); it is more reactive toward dilute acids; it
shows a different appearance under the microscope; and its DTA endo-
therms and exotherm are shifted relative to those of the latter (and
apparently diminished).
2. The presence of ehrysotile as a minor constituent in talc may
he established with reasonable certainty on the basis of (a) the
presence of x-ray diffraction peaks in the vicinity of 7*23 to 7.^3 A
and 3-59 to 3*65 A, (b) the pronounced weakening or complete disappear
ance of these peaks upon treatment-up on .tn&atgent- of the specimen
with 1 M HC1 at 80C for 1 hour, (c) the presence of fiber bundles of
visible size under 250X or higher magnification in the optical micro
scope which show a refractive index of about 1.54 (these fiber bundles
may be short and straight, and may he coated with a bumpy encrustation
of Mgcfo^, or may be embedded in talc or other particles), and (d) the
presence of fibers under the electron microscope which yield an electror
diffraction pattern that corresponds in d-values to those found in the
x-ray diffraction pattern (these fibers typically do not have a hollow
central capillary running through them).
3 . The concentration of ehrysotile in a talc may he estimated by
measuring the area under the x-ray diffraction peak at about 7-3 A
~
-'e on -*nt-.fim a l standard. The best internal standard
HHS00000207
3
is calcium oxalate monohydrate (peak at 583 A). 4. The quantitative results are conditioned ty the fact that
segregation effects in talc powders are considerable; the analytical method gives a reproducibility of 2 to 3$ average deviation in replicate determinations on the same sample, but different samples from the same bulk container are found to vary by as much as 200$.
5. The quantitative results are further complicated by the fact)i that antigorite gives an x-ray pattern that is indistinguishable from that of chrysotile. The HCl treatment specified above does not affect ground antigorite, but it is not yet known whether antigorite, if it occurs in talc, has the same chemical reactivity as the ground material from massive antigorite, or whether (like chrysotile) its properties may be variable depending upon the rock matrix in whicp it is found.
6. Subject to the qualifications inherent in the above, we have obtained quantitative estimates of the chrysotile contents of about 200 commercial talcum powder specimens. We have also determined the contents of the other minerals in these products, including tremolite, quartz, chlorite, dolomite, and others. There is no ambiguity in the identification of these latter species, but _the quantitative results for these are also affected by the segregation problem, which is most serious for those constituents present in the smallest amounts.
7. Most of the commercial talcs tested are free of any detectable amount mf any of the asbestiform minerals, according to the criteria enumerated above. Thus, there appears to be an adequate supply of talc for which there is no ambiguity about the absence of chrysotile or tremolite. In about 10$ of the samples tested, there appear to be definitely detectable amounts of either chrysotile or tremolite present.
HHS00000208
SAMPLE NO.
1
Zq
TABLE I I
INTERLABORATORY COMPARISON OF ANALYTICAL RESULTS FOR TREMOLITE IN COSMETIC TALCUM-TYPE POWDERS
________________________________________________ RESULTS
N .Y .U .
FDAa
(X-RAY DIFFRACTION)
(OPTICAL MICROSCOPY)
PFIZER6 (X -R A Y DIFFRACTION-)
n. d. (not detected)
2
n. d.
3
n. d.
4
n. d.
5
n. d.
6
n. d.
7
n. d.
8
n. d.
9
n. d.
10
n. d.
11
n. d.
12
n. d.
13
n. d.
14
n. d.
15
n. d.
16
c
17
n. d.
18
n. d.
19
n. d.
20
n. d.
21
n. d.
22
n. d.
HHS00000209
SAMPLE NO. 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48
_______________________________ RESULTS____________________________
N.Y.U.
FDA.
PFIZER
(X-RAY DIFFRACTION)
(OPTICAL MICROSCOPY)
(X-RAY DIFFRACTION)
n.d.
n.d.
n.d.
tu d.
n.d.
n.d.
n. dr
n. d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n. d.
n.d.
n. d.
n. d.
n.d.
n.d.
n.d.
--
n. d.
n. d.
n.d.
n.d.
HHS00000210
SAMPLE WO.
49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74
_________________________________________________ RESULTS_____________________________________________
N .Y .U .
' FDA.
PFIZER
(X-RAY DIFFRACTIOK)
(OPTICAL MICROSCOPY) (X-RAY DIFFRACTION)
n. d.
n. d.
n; d.
n. d.
n. d.
n. d.
n. d.
n. d.
n.d.
n. d.
n. d.
n.d.
n. d.
n.d.
n. d.
n. d.
n. d.
57
moderate amount
n.d.
n. d.
n. d.
2%
n. d.
n. d.
n.d.
small amount
37,,
n. d.
n. d.
n.d.
n. d.
n.d.
small amount
i'.V.WKiKK v.v.-.'.ii::::
HHS00000211
SAMPLE NO. 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100
N. Y. U(X-BAY DIFFRACTION)
n. d. 5/L 3% 5% n, d. n. d. n. d. n. d. n. d. n. d. ti. d. n. d. n. d. 4% 5%
37.
n. d.
57 57.
4% 2% 8% 12% n. d. n. d. n. d.
RESULTS FDA
(OPTICAL MICROSCOPY)
PFIZER (X-RAY DIFFRACTION)
small amount. moderate amount
rud.
n. d.
n. d. large amount large amount large amount
large amount large amount large amount
moderate amount large amount
n. d. very small amount
1.6%
1.9% 0.7% 8.1%
HHS00000212
MPLI 101
102 103 104 105 106 107 108 109 110
111
112 113 114 115 116 117 118 119 120 121 122 123
N. Y. U.. (X-RAY DIFFRACTION)
157o 107= n.d. n.d. n. d. a. . n.d. 2% 2 7. n.d. 17= n. d. . n. d. n. d. n. d. n. d. n. d. n. d. n.d. n- d. n. d. n.d. n. d. n. d. n. d. n. d.
, RESULTS_______
FDA
(OPTICAL MICROSCOPY)
large amount
large amount
PFIZER (X-RAY DIFFRACTION)
10 to 157=
HHS00000213
SAMPLE KO. 127 12 S 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 '150 151 152
N.Y.U. (X-RAY DIFFRACTION)
n. d. n. dn. d. trace trace n. d. n.d. n. d. n. d. n. d. n. d. n.d. n. d. n. a. n.d. n. d. 57. 57. n. d. n. d. n. d. 27. 87. n. d. n. d. n. d.
RESULTS FIA
(OPTICAL MICROSCOPY)
PFIZER (X-RAY DIFFRACTION)
small amount present
n.d.
HHS00000214
SAMPLE NO. 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178
N. Y. U. (X-RAY DIFFRACTION)
n. d. 2% n. d. 2% 6% n. d. n. d. n. d. n.d. n. d. 10% n.d. n.d. n. d. 2%
mi --
n.d. n.d. 2% n. d. n.d. n.d. n.d. n. d. n. d.
RESULTS____________
F D.
PFIZER
(OPTICAL MICROSCOPY)
(X-RAY DIFFRACTION)
small amount
approx. 0.5%
large amount n. d.
3.8%
HHS00000215
SAMPLE KO.
179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195
_______________________________ RESULTS____________________________
N .Y .U CX-RAY DIFFRACTION')
FDA (OPTICAL MICROSCOPY')
PFIZER (X -SA Y DIFFRACTION)
n. d.
n, d.
n. d.
n. d.
17.
37.
n. d.
n. d.
27.
17.
17.
n. d.
n. d.
n. d.
n. d.
n. d.
n.d.
Footnotes :
a. Work done by Mr. Arnold E. Schul2 e, Division of Microbiology, (See Appendix A) b. Pfizer, Inc.;- Minerals, Pigments, and Metals Division, Easton, Pa. c. The use of a dash means that the powder does not contain talc and therefore
is not expected to contain tremolite or chrysotile as contaminants. No asbestos was found.
HHS00000216
SAMPLE NO,
X 2 3 A 5 6 7 8 9 10 11 12 13 14 15 16 17 18' 19 20 21 22
fUo
TABLE III
INTERLABORATORY COMPARISON OF ANALYTICAL RESULTS FOR CHRYSOTILE IN COSMETIC TALCUM-TYFE POWDERS
_______________________________ RESULTS_____
N.Y.U.
FDA
PFIZERa
(X-RAY DIFF.)
(OFT. MICE.)
(X-RAY DDT.)
md.(not detected)
COLUMBIA SCIENTIFIC^
n. d.
n. d.
n. d.
n. d.
n.d.
?
XL-d.
n.d.
n. d.
n. d.
n.d.
n. d.
n. d.
n. a.
--
n.d.
n. d.
n.d.
n.d.
n.d.
n.d.
K?BC
A*,V ;ususs; HHS00000217
AMPLE NO.
23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48
_________________________________________________ r e s u l t s ______________________________________________________
N. Y .U .
FDA
PFIZER"
COLUMBIA
(X-RAY DIFF. )
(OPT. MICR. )
(X-RAY D IF F .)
S C IE N T IF IC 1* HPBC
?
n.d.
?
?
n. d.
n. d.
n. d.
n. d.
n.d.
<
n.d.
n. d.
n. d.
n. d.
n.d.
n. d.
n. d.
n. d.
n.d.
n.d.
n. d.
n.d.
--
n.d.
n. d.
n.d.
n. d.
HHS00000218
K. Y. U. (TX-RAY DIFF.)
RESULTS
FDA
PFIZER2
(OPT. MIGRAI
(X-RAY DIFF-1
COLUMBIA s c i e n t i f i c ]^
H?BC
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
HHS00000219
SAMPLE NO.
75 76 77 78 79 80 81 82 S3 84 85 86 87 88 89 90
N. Y. U. (X-RAY DIFF- ) n. d. n. d. n* <L n. d. n. d.
1
? 7 ? ? 7 ? 7
57. 57. 57.
91 '
57.
92
57.
93
47
94
?
95
37.
95
107.
97
15%
RESULTS
FDA
PFIZER3
(OFT. KICK.)
(X-RAY DIFF.)
n. d. n.d.
n. d.
n.d.
n. d.
n. d. n. d. possible, in talc grains
n. d.
possible, in talc grains
much antigorited ?
n. d.
possible, in talc grains
moderate antigorite?
n. d. n. d.
COLUMBIA SCIENTIFIC5
HPBC
inconclusive
inconclusive inconclusive <0.17. inconclusive
k:kv.sv.;
HHS00000220
AMPLE NO.
98 99 100
N. Y. U. OC-BAY DIFF.) n. d.
n. d. n. d.
101
n. d.
102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122
7% n. d. n. d. n. d. n. d. n. d. n. d.
? n. d. n. d. n.d. n. d. n. d. n. d. xv. d.
1
n. d. n. d.
? n.d.
?
RESULTS
FDA
PFIZER^
(OPT. MICR. )
(X-RAY DIFF.-)
COLUMBIA SCIENTIFICb
n. d.
possible, in talc grains
much antigorite?
n. d.
n. d.
n. d.
n. d.
.V.'.iV.VS wnvvff
sn;uvA;vA*.wa`:::
urntnanuntn
HHS00000221
AMPL NO. 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142
143 144 145
N.Y.. (X-RAY DIFFO
RESULTS
FDA.
' PFIZER3.
(OPT, MICR.)
(X-RAY DIFF. )
COLUMBIA SCIENTIFIC*3
HPBC
HHS00000222
AMPLE NO. 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164
165 166 167 168 169 170 171 172 173 174'
N.Y.U. (X-RAY DIFF.)
7 n. d. n. d. n. d. n. d. n. d.
? n. d. 8% n.d.
7 trace n. d. n.d. 10% 1%
1
7 n.d.
ZZ.
-87. n. d. n. d.
7 n. d.
RESULTS
FDA
PFIZER"
(OPT. M1CR. )
(X-RAY PIFF.)
n. c.
n.d. n.d.
0.11e
n.d.
possible, in talc grains
n. d.
COLUMBIA _ SCIENTIFIC^
HPBC
n. d.
inconclusive
n. d.
HHS00000223
SAMPLE NO.
175
176
N.Y.D. (X-RAY DIFF.)
9
?
RESULTS
FDA
PFIZER3,
(OPT. MICR.)
(X-RAY Diff,)
COLUMBIA SCIENTIFIC13
HPBC
*
177
n. d.
178
?
179
n. d.
180
n. d.
181
n.d.
182
n
183
?*
184
n.d.
185
n. a.
186
?
187
n.d.
188
,
189
n. d.
190
?
-
191
n.d.
192
n. d.
193
194
?
195-
n.d.
ootnotes: Pfizer, Inc., Minerals, Pigments, and Metals Division, Easton, Pa. Columbia Scientific Industries, Austin, Texas, using Differential Thermal Analysis.
:. Health Protection Branch of Canadian Government, Ottawa, by electron microscopy, oral communication-by Drs. Pontefract and Cunningham. Antigorite is a non-fibrous form of the same mineral as chrysotile.
;. By transmission electron microscopy.
... ...
t--.,. *... i.-.v.v.r.v !==TM Hr!
fesmau
b----- & kuuussr
..........
i... s= p r: : = =
HHS00000224
AMPLE NO. 1 2 3. 4 5 g 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
F'Z TABLE IV
KEY TO SAMPLE NUMBERS OP COSMETIC TALCUM-TYPE POWDERS
PRODUCT NAME Ammens Powder, Medicated Amolin Deodorant Powder Aquamarine Cooling Spray Bath Powder Bagatelle Amber Dusting Powder Bourjois Bath Powder Caldesene Medicated Powder Cashmere Bouquet Body Powder Chanel No. 5 Bath Powder Countess Rocheau Cake Dusting Powder Crepe De Chine Dusting Powder, Millot Crepe De Chine Poudre Mist, Millot Cuticura Talcum Powder Desenex Desitin Baby Powder Desitin Baby Powder Diaparene Baby Powder Dorothy Gray "Secret Or The Sea" Dusting Powder Emeraude Talcum Powder English Leather Faberge "Music" Dusting Powder Friendship Garden Dusting Powder Friendship Garden Dusting Powder Friendship Garden Dusting Powder
FURTHER IDENTIFICATION Bristol-Myers (No, IF25) Norwich Revlon (143) Corand (DCS)
h-v.-.t:::::::
--. !
Pennwalt (5274) Colgate-Palmolive
Jergens
KM:: i
%
\ \ \ \
ir."" .V.V.V.V.V
XBBWSSBS
House of Fragrance (L1132)
House of Fragrance
W.*W;,
Purex (07170)
FES-Pharmacraft
Pfizer (1139Z) (3/29/72)
Pfizer (115A) (5/10/72)
Breon (E1030)
__L_. W~S3
Coty (355-4010) Mem (2891) Shu1ton (3/27/72) Shulton (5/9/72) Shulton (7/13/72)
:r.--r:::; js;
P.-.-.'.: === ...
P''g:-;;
HHS00000225
PLE 0. 4 5 !6 27 28 29 30 31 32 33 34 35 36. 37 38 39 40 41 42 43 44 45 46 47 48 49
- PRODUCT NAME Heaven Sent Aerosol Bath Powder Mist Heaven Sent Bath Powder Helen Press1 "Little Lady" Imports. Spain Mens' Talc Isis Floral Talcum Powder Johnson's Baby Powder Johnson and Johnson Medicated Powder Koscot Beauty Dust-- Oil of .Mink Lanvin Arpege Dusting Powder Lanvin Arpege Powdered Mist Laxrvin Arpege Talc Lewis Baby Powder Loves Fresh Lemon Glossy Powder Macy's Scented Berated Talcum Macy's Talcum, Apple Marcelle Dusting Powder, Hypo-Allergenic Mary Chess Perfumed Dusting Powder Mennen Baby Magic Powder Mennen Quinsana Foot Powder Merck Talc, Product No. 6460, Lot No. 6460) Mexsana 2387-D Medicated Powder Old Spice Body Talcum Persian Lilac Deluxe Dusting Powder Persian Lilac Spray Bath Powder Pond's Perfumed Tale Body Deodorant Dream Flower Prince Matchabelli Beloved Spray Powder
FURTHER IDENTIFICATION Rubinstein Rubinstein
(02SQ) (3612) (1288)
Manley 6 James
(2K4)
(B112) (H202) (8039301) Plough Shulton April Showers (LFN) April Showers (B200B) (115B)
ii.v :.v .v .-.v .v
:M*.asatKS5 tt'.*4VAV.`.v.r
HHS00000226
'MPI
NO.
PRODUCT NAME
50
Quest Deodorant Powder
51
Replique Spray Bath Powder
52
Riviana Foods - Italian Stearin Talc
53
September M o m By Pond's
54
Seven Winds After Bath Talc
55
U S P Talc
56
Vaseline Intensive Care Baby Powder
57
Yves Saint Laurent Rive Gauche Spray Talc
58
Z B T Baby Powder
59
Zeasorb Super Absorbent Medicated Powder
60
Ambush-Dana Dusting Powder
61
April Showers
62
Avon Unforgettable Perfumed Talc
63
Beloved Perfumed Dusting Powder, Prince
Matchabelli
64
Coty Face Powder Rachel
t.
65
Desert Flower Spray Bath Powder
66
Emeraude Dusting Powder
67
Emeraude Spray Dusting Powder
68
Faberge Flambeau Deodorant Spray Powder
69
Jean Nate Spray Bath Powder
70
Jeris Talc, Flesh
71
Jolie Madame Dusting Powder, Balmain
72
Lady Esther Face Powder, Rachel
Max Factor Face Powder, Rachelle
Medicated Comfort Powder
OH.' de London Talc
FURTHER IDENTIFICATION Parfums Raphael (004) For Rice (19B)
DuBarry ( 0 2 1 0 8 5 ) (I 209) (F 1 0 2 1 )
Stiefel (9884)
Shulton (F 1 BRI) Coty Coty (1 AEY) (37 WBF) (1 M 247)
Parke-Davis Yardley (498)
HHS00000227
KPLE
no. 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101
PRODUCT NAME To Know Me Is To Love Me - Tinkerbell Touch And Glow Face Powder, Creamy Peach Toujours Moi Bath Powder Yardley April Violets Chantilly Dusting Powder Cashmere Bouquet Jean Nate Talc Mermen Shave Talc Shower To Shower Body Powder Pure Baby Powder, Dart Drug Pond's Dream Flower Perfumed Talc Almay Hypo-Allergenic Face Powder Constance Carroll, Bouquet Talc Djer-Kiss Talcum Flamingo Dusting Powder, Tussy Lander Lilacs And Roses Talc Mavis Talcum Mavis Body Powder Tangee ZBT Baby Powder Blanchard's Dusting Powder Born Wild Dusting Powder Lander Gardenia And Sweet Pea Talc Lander Lilacs And Roses Deodorant Body Talc Miss Dior Dusting Powder Tai Winds Spray Talc
FURTHER IDENTIFICATION Tom Fields, Ltd. Revlon Corday (4908) Roubigent (1IF)
r.v.v.v.v.-;;.-;
(on 345) (B 81)
Johnson & Johnson (5507BG)
(K 11C) (0 13 D)
i.* ::::::::::;- .
Kerkoff (L1047)
t;":
B-.mv.v.v.
Vivaudou Vivaddou Luft-Tangee (B0048)
Del Labs
(Avon (DCC 1272 2-14-72,HWS)
:S V .W ,B B V .V .K
HHS00000228
PLE
$0.
32
PRODUCT AME
Tosca Dusting Powder
03
Coty L'Aimant Talcum Powder
04
Coty Emeraude Talcum Powder
05
Coty L'Aimant Dusting Powder
.06
Coty Imprvu Dusting Powder
-07V Coty Muguet des Bois Dusting Powder
-08
Revlon Intimate Perfumed Bath Powder
L09
Jean Mat* Bath Powder
110
Jean Nate" Spray Bath Powder
111
Old Spice Body Talc
112
Dr. Scholl's Foot Powder
113
Faberge Xanadu Luxury Bath Powder Spray
114
Faberge Zizanie de Fragonard
115
Faberge Tigress Bath Powder
116
Faberge Woodhue for Men
117
Faberge Brut for Men Shower Buff All-Over
Body Powder
118
Faberge Talc
119
Faberge Aphrodesia Bath. Powder
120
Faberge Straw Hat Bath Powder
121
Faberge Aphrodesia for Men Shower Buff
122
Faberge Xanadu de Luxe Bath Powder
123
Faberge Woodhue Bath Powder
124
Faberge Music Dusting Powder
125
Faberge Flambeau Bath Powder
FURTHER IDENTIFICA.!IO'
(1JJ)
'(01A) <1M)
(IDE)
(2 DO)
(241.) Lanvin - Charles of the Ritz (2137)
Lanvin - Charles of the Ritz (2103)
Shu1ton. Inc. (MFC)
(20517)
.. SS;
(2132) Ref. 61159-019 Ref. 2052-003 Ref. 5027 (0252) Ref. 5400
(raw material: from France) Ref. 2 052 (2 172)
Ref. 5027 Ref. 1244-028 (2342) Ref. 2052-002 Ref. 0714-018 (3121) Ref. 2052 (3471)
aiw rM fre sig fffrssstfsssissg xstsssfi& ffT X i
HHS00000229
IMPLE NO. 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143
PRODUCT NAME Menuen Baby Magic Walgreen's Crib Age Caldesene Medicated Powder Desiten Vaseline Intensive Care Johnson and Johnson Medicated Powder Johnson Baby Powder Johnson's Baby Powder Johnson's Baby Powder Johnson and Johnson Medicated Powder Johnson and Johnson Shower to Shower Body Powder Johnson and Johnson Shower to Shower Body Powder Johnson and Johnson Shower to Shower Body Powder Avon Brocade Sp.ray Avon Bird of Paradise Spray Avon Tai Winds Spray Talc Mennen Bath Talc Pin-Zow Talque
144
Overton's "High-Brown" Face Powder
145
Softee Face Powder
146
Westport Face Powder
147
Hazel Bishop Pressed Powder
148
Lady Wayne Face Powder
149
Solitaire Cake Makeup
150
Dreamglo Pressed Powder
* FURTHER IDENTIFICATION
(108T) (109T) (0452 K) (C 512Z) (0709X1) (0872K) (31602) (B1652) (4065) (A308) Perfection Beauty Products.
Inc., Pearl River, N.Y.
HHS00000230
iMPLE NO.
PRODUCT NAME
L51
Early American Old Spice Talcum Powder
152
Corsage Dusting Powder
153
Asumens Powder, Medicated
154
Bismoline Medicated Powder
155
Rite Aid Pure Baby Powder
155
Warner Pure Baby Powder
157
Mavis Imported Talcum
158
Avon Brocade Perfumed Talc
159
Avon Blue Lotus Perfumed Talc
160
Avon Beauty Dust Refill - Charisma
161
Avon Elusive Beauty Dust Refill
162
Avon Rdgence Perfumed Talc
163
Pinaud Clubman Talc
164
Grand Union Baby Powder
165
Cashmere Bouquet
166
Almay Pace Powder, Soft Beige
167 Tawny Tone Body Talc Prom Black Heritage
168
Colgate Tooth Powder
169
Dr. Lyon's Tooth Powder
170
"C" Bouquet TAlc.
171
Tangee Dusting Powder
172
Jeris Talc
173
Corsage Dusting Powder
174
Lander Gardenia & Sweet Pea`Deodorant Body Talc
FURTHER IDENTIFT.CA.TIQK Lander
(101672) (4212DX) (Supplied by Mfgr.) (List No. 719, Lot 201,
Supplied by Mfgr.) (Beauty Mustus, Inc. Greenwich, Conn.)
(Winarick, Inc. Distr. by F. W. WooIworth)(2662) (George W. Luft Co.)(2762) (Winarick) (2732) (Lander Co.)
! i!H!!tl! 1!I11j||ItlH!j|11[|PIHfli
HHS00000231
AMPLE NO. 175 176 177 178 179 180
PRODUCT NAME Lander Baby Powder Lander Lilac & Roses Body Talc Beloved Perfumed Dusting Powder Jean Nat/ Talc No. 60 Jean Nat/ Spray Bath Powder Tihkerbell Body Talc
181 182 183 184 185 186 187 188 189 1190 191 192 193 194 195
Yardley Sigh Shadow Brush-On Eye Shadow Max Factor Face Powder, Rachelle Tweed Bath Powder, Lentheric Yardley Next to Nature Sheer Pressed Powder Yardley April Violets Dusting Powder Yardley Red Roses Dusting Powder Yardley Springflowers Talc Yardley White Lavender Talc Yardley Red Roses Talc April Showers Deodorant Talc Chantilly Houbigant Dusting Powder Tinkerbell Dusting Powder Tihkerbell Powder Mitt Tinkerbell Dusting Powder Tinkerbell Body Talc
FURTHER IDENTIFICATION
Prince Matchabelli (235A) (2264) (2101) (Tom Fields, Ltd.,
Div. of MEM) Ref. No. 721 (Supplied by Mfgr.) (Yardley)(44) (A2) (162) (165) (260) (271) (214) Ref. No. 9882 (2JBB) (Tom Fields, Ltd. ) (Tom Fields, Ltd.) (Tom Fields, Ltd. ) (Tom Fields, Ltd.)
HHS00000232