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CL r ae M Specly Matera o2f3 5p. ORIGINA SMeteessa tom S17 00 FY-1200-H020313827& AR 226 - 0976 RAEPCPETIVCEBD WONFC22 i 7:08 VIA OVERNIGHT DELIVERY WIEIEAARRNER December 19, 2000 FY1-00-001378 ot For Your Information Docket [Docket AR-226] ODfofcicuemeofntPolPlruotcieosnsPirnegvCenetnitoenra(n7d40T7o)xics U.S. Environmental Protection Agency 401 M Street SW Washington, D.C. 20460 2 an o8S Sz -- Bia 2 ge = 2 Re: Information on Perfluorooctane Sulfonates and Related Compounds Dear Sir or Madam: sulfonaTtheissacnodntrienluaetesd3cMo'mspvooulnudntsa,ryassupbamrtiosfsioounr soonfgdoaitnagodniapleorgfwiiutohroEoPctAane regarding fluorochemistry. Contents of this Submission Initial Assessment Report PerfluoWreoocatraenperSouvlifdoinnigcaAcciodpyanodf 3IMts'Ssaldtrsa,ftdIantiteidalOAcstsoebsesrm2e,n2t00Re0pwoirtthotnhis submission. This draft document was provided to membersofthe OECD aEtxiEstPiAngoCnhOecmtiocbaelrs 2T6a-s2k7,Fo20r0c0e.forTthheeirdorcevuimeewnptriiosrsttilolaatdercahfnticsaulbjmeecetttiong held modification as new data become available. However, we are providing a copy so that this comprehensive document and accompanying robust summaries will pbreoavviadieldabilneotuor tsheeripeusbloifcsiunbmEiPsAs'isondso.cket along with all of the raw data we have The enclosed draft report follows the format outlined in theScreening Information Data Set (SIDS) Manual of the OECD, even though perfluorooctane esuvlefnontihcoaucgihd t(hPeFdOaSt)a issentootncoPnFsOidSeriesdsuabshtiagnhtiparloldyumcotiroen rvoobluustmethcahnemtihcaatlc,ovaenrded in most initial assessment reports. 8A5U01E00R00E00E7RL Contaalin NO cCeHi r Ja * DPeacgeem2ber 22, 2000 and This draft report summarizes the presents and evaluates information ionnfoPrFmaOtSionexapvoasiluarbeleanads obfioJluolgyic2a0l,e2ff0e0c0ts ipnreavnioiunistliayl parsosveidsesdmeanCtDofspeottecnotnitaalinhiunmgatnhehueanldtehrlaynidngesctoulodgiiecsarlelriieskd.u3pMonhainsthis draft body report, of data For some reviewed isntutdhiisesd,rarfetporreptosratrseusgtgilesitnsprtehpaatrhatuimoan.n The substantial serum levels faoduvnedrsien ohcecaultphateifofencatls.anSdimniolnar-loyc,culepvaetlisofnoalunpdopinultahteioennsviarroennmoetntasasnodciiantweidldwliitfeh are not associated with adverse effects. the origAisnawlictohvoetrhelerttCeDr sansdubtmhietItneitdiablyAs3sMe,stshmeeenntclRoespoerdt.CDThiensceluedleesctarocnoipcy of dmaoicnutmaeinntpsapaerre fcoorpireesa,d-aonndlyinptuhrepoesveesntaonfdaanrye dniostctroepbaencmyo,ditfhieed3.M3pMapweilrl copies will be considered controlling. We available. will continue to | will be retiring pfrroovmid3eMineffofercmtaitvieonFeobnruaarreygu1,la2r00ba1s.isYaosu it becomes may feel free to contact me until then, or after that, please contact my successor Michael Santoro (651-733-6374) with any questions. Very truly yours, Hoi C. Higorns William A. Weppner, Ph.D. DSiarfeecttyoranodf ERnevgiurloantmoernytaAflf,aiHresalth Specialty Materials Markets Building 236-18-10 3M Center St. Paul, MN 55144 651-733-6374 (phone) 6E-5m1a-i7l3:3-w1a9w5e8p(pfanx)er@mmm.com ce: Dr. Charles Auer Dr. Oscar Hernandez (without enclosures) Contain 07 CBI +b