Document npVqBQdb99k877MoK5mrQO3xX

FOR DU PONT USE ONLY HASKELL LABORATORY Common Name: Dibasic Lead Phosphite (Dyphos) Chemical Name: Lead Oxide Phosphcnate, Kemihydrate (9 CI) Synonyms: C.I.77620 Lead Dibasic Phosphite Lead, Dioxo (Phosphito (2-)) Tri-, Hexaihydrate CAS Registry No.: 1344-40-7 Chemical Structure: Lead Monoxide 90% by wt Phosphorus 4% by wt 2PbO PbHP03 1/2 H20 Chemical and Physical Properties (1) Appearance: Specific Gravity: Refractive Index: Solubility: Fine white acicular crystals 6.94 2.25 Insoluble in water Threshold Limit Value (2) Lead: TWA = 0.15 mg/iti3 DOT Classification (3 > Flammable Solid TOXICITY A. Acute Oral 0 The o;ral toxicity of Lead Phosphite was very low. LD50 (rat) > 6000 mg/hg (4). B. Extended Studies N 27653 Oral Following subacute or chronic application of higjh amounts of Lead Phosphite no signs of damage were found in the experimental animals. "This may be explained by the poor absorptability of these practically insoluble substances in the gastrot intestinal tract" (4). DUP040010722 No additional information was found; however all pre cautions as with lead use should be followed. C. Related Information ,CA 75 ; 130455m Vinyl chloride polymers containing lead com- i pounds as stabilizers. Heijo, Ichio; Nakagawa, Yoshitaka; Yoked, Masatada (Mitsubishi Resin Co., Ltd.) Ger. Often, 2,062,313 (Cl. C C8/), 24 Jun 1971, Japan. Appl. 18 Dec 1969; 19 ppi- The extn. of toxic Pb from water pipes manufd. from PVC and vinyl chloride copolymers contg. tribasie Pb sulfate, dibasic Pb:. phosphite, or a similar stabilizer is reduced .to a safe level by incorporating mto the polymer 015-570% monobasic ordibasic Ca pSosphate, NafibUj, k 'phosphate, dibasic Wa pfioiphate, Na phosphite, or N'a,COi which convert water-sol, PbCL formed from thftsta'hilizprtn another Pb salt having low ivater-soly. REFERENCES 1. Hawley/ G. G., The Condensed.Chemical, Dictionary, 9th ed,, (1977). 2. TLV Booklet 1977, 3. NL '(National Lead) Industrial Chemicals. Data Sheet, 2/15/78. 4. Klimmer', O. R. adn. I. U. Nehel, Arzneimittei-Forsch, 10; 44-48 (I960) . Pamela Sort ;md March 22, 1978 DUP040010723