Document np8rBR74y4Z3BXj4zNe1e3gyX

Th e Pe n n s y l v a n ia St a t e Un iv e r s it y 226 CHEMICAL ENGINEERING II UNIVERSITY PARK, PENNSYLVANIA 16802 C e n t e r for A ir E n v ir o n m e n t '.Stu d ies . Area Cole 814 865-1415 Form Approved Budget Bureau No. 85-S69020 Reference Number.: 275b AIR POLLUTION RESEARCH PROJECTS 1969 If you have research projects during 1969, please complete the entire questionnaire. If you have no air pollution research projects during 1969, please check the box below and return. ^-- | ; . Organization: Address: Eden Avenue, Cincinnati, Ohio 45219 Title of Project : Human Exposure to Particulate Lead Compounds in tue Air J Under Experimental Conditions Principal Investigator(s): Robert A. Kehos, M.D., Professor Emeritus Cin charge) with Various members of the Staff of the Kettering Laboratory - principally, J. Cholak, Professor (and Chief Analyst), Lawrence J. Schafer, Assistant Professor (and general Supervisor), and others (physicians, clinical mlcroscopists, biochemists) Location of Research: Kettering Laboratory Expected Duration of Project: General investigation of lead metabolism in human subjects has been under way since 1939; will continue indefinitely - the practical problem of the tolerable concentration of lead in the ambient air is but one phase. community health since inception, under agreements with the Administration of the WgtSi-` .Additional funds were supplied for a period of five years from the u.S. Public Health Service, Division of Air Pollut Brief Summary ox Description: (SEE OVER) Title(s) of Resulting Paper(s), Author(s), Journal, Volume, Date, and Page(s): (SEE OVER) Please indicate, on back of one of the report forms submitted, names of I Wa&fcirector, Raymond Suskind, M.D., who will be here by the middle of August. NAPCA form No. HQ 33 (5/69) V, .V SUMMARY : Brief summary useless. The purpose has been that Of determining th maximum level of the concentration of lead in the air which when added to the background of other environmental factors (chiefly that in food and beverages) can be handled by the excretory, mechanisms of the body without any measureable elevation of the daily output of lead or any measureable increase in the \ concentration of lead in the blood - that is without measureable indication of an alteration of the equilibrium now being maintained (by normal individuals) between their intake and output of lead during prolonged periods (months and years) of experimental observation. PUBLICATION : Incomplete - periodically in relation to significant results of prolonged experimentation, by RAK, speaking for the group in publications best d described as Progress Reports. (1) Kehoe, Robert A.: The Metabolism of Lead in Health and Disease. The Earben Lectures of 1860 - J. Roy. Inst, of Public Health and Eyg. 24:(April) 81-97, (May) 101-120, (June) 129-143, (August) 177-203; 1961. (2) Kehoe, Robert A.: Experimental Studies on the Inhalation of Lead by Human Subjects. Pure and Applied Chemistry 8:1-2, 129-144, 1961. (3) Kehoe, Robert A.: Criteria for Human. Safety, from the.Contamint ion of tne Ambient Environment witn Lead. Proceedings of the KV International Congress on Occupational Health, Vienna Austria, September 1966, Vol. Ill, 83-98 - Verlag der Wiener Mediainischen Academia, Vienna, 1966. KE 0019698