Document np5mjyYZ68og2LbDbpozENpd6
1* -
was most frequently the antioxidant monobenzyl ether of hydroquinone,
which is used in the rubber adhesive in the combined linings-of the shoe.
Some of these patients were specifically sensitive to other rubber anti
oxidants and accelerators.
-- Authors' Summary
tie a rb 1eraHe
r*
.
k
t
r.i
&
1
j -
.` gens
the
in
r.
i i
' Vi
964 Occupational Arsenical Dermatitis: A Study among Employees at a Copper-Ore Smelting Work, Including Investigations of the Skin Reaction to Contact with Arsenic Compounds. I. Holmquist. Acta dermatovenereol. M.* Supp. 26, 1-214 (1951).
The sensitizing effect of several arsenic compounds was studied
in employees of a copper-ore refinery by means of patch teBts. Positive
reactions to pure arsenic trioxide were shown in 80.471 of arsenic workers,
35.2% of other employees, and 30.3% of new employees, independently of
age groups. Ointments (50% arsenic trioxide) with antipyrene or alkaline
base caused more positive reactions than those with petrolatum base. A
1% solution of disodium arsenite caused positive reactions only in sensi
tized persons, but a 2% solution induced positive reactions in all cases.
A 5% solution of arsenic pentoxide affected all persons, while a 2.5%
affected only sensitized Individuals. Few positive reactions occurred with '
lead and calcium arsenates, on account of their low solubility.. Tests were
also made with non-arsenical compounds in solution; 0.5% chromic acid,
0.1% mercuric chloride, 10% nickel sulfate, 5% silver nitrate, and 1%
potassium dichromate caused only 1 to 4 positive reactions in a large
number of tests. Sodium selenite and selenious acid in 0.5% solution
failed to cause allergic reactions. Concentrations of selenious acid above ...
1% had pronounced toxic irritative effects. Corrosive reactions occurred ,.>/
with sulfuric acid in concentrations above 5%, independently of arsenic
.;
exposure. The factory operations are reviewed in detail, and statistics
on arsenic sensitization in various operations are given.
-- Cond. from Chero. Absts. . --'Mi
965 Harmful Effects on the Skin of Dichlorodiethylmethylamine (Nitrogen Mustard). M. Leder. Dermatologies 104, 176-179 (1952) German.
Skin changes produced by nitrogen mustard gas were similar to
those seen after exposure to ordinary mustard gas. Nitrogen mustard gas
appeared to have_a_longer latent period and produced changes associated
with increased sensiflvTtyr - -
-- Chem. Absts.