Document nkdYMj3r2829eZdqJbkOBv871

' '. ' i t / .- ::' ''!i. < E AS S OCIATED E TH YL COM P AN Y LIM ITED N ORTH W ICH CH ES H IR E Telephone:NORTHW1CH 2237. T elegram s & C h iles, e t h y l p o r t , n o r t h w i c h . O ffice/ e , j f & a d a r t il l er y h o u s e, A R T I LLER Y ROW , LO N D O N , S.W .l. OUR REF. K .2 . A BBEY 3 0 7 4 . V O U RREF. DATE 27t h Ja n u a r y , R .A . Keh oe, E s q ., M .D., Ketter in g Laboratory o f Applied P h ysiology, College of M edicin e, U n iversity o f Cin cin n ati, Eden Avenue, OHIO, ' U .S.A . .' V 1948 directors: N. A .G A SS. J. e . A U G - K ES S L ER , {N ET H ERLA N D S) J- W . B O Y LE. ' r.G .C.M O R R 'S. R .H .P O R T ER S. R .W .SELLER S. D. A . SH EP A RD , (u. S. A ) A. J.SI N G LET O N . G. SRRY. . t . r . a . b e v a n , f M anagingj 'r. D ear D r . Keh oe, I th ou gh t you m igh t be in t e r e st e d in th e p r e se n t st a t e a t t h is P lan t an d in th e Company g e n e r a lly , and t h e fo llo w in g n a r r a t iv e sh ou ld p u t you in th e p ict u r e fo r Mr. Bevan 's v i s i t , which I b e lie v e i s plan n ed fo r e a r ly y . F e b r u a r y . Mr. Ban ks i s accom pan yin g h im . When I r e t u r n e d h er e on t h e 19t h December I fou n d c o n d it io n s f a r from s a t i s f a c t o r y . T h is was due t o t o o much a t t e n t io n by t o o few p e r so n n e l b ein g given t o th e docu m en tation con com itan t w ith th e ch an geover from B r it ish Et h y l t o A sso ciat e d Et h y ljan d t oo l i t t l e t o h y gien ic co n d it io n s on th e p la n t . The a i r fi g u r e s in ou r le a d sm e lt in g b u ild in g w ere v e r y b a d . In t h e l a s t few d ay s o f December t h ey w ere 5*6 4 ,9 , 56 an d 1 4 .7 mgms. le a d p er 10 c u b ic m e t r e s. The p h y sio lo g ic a l sam p le s, e s p e c i a l l y fo r fa e c e s, w ere a s u n sa t isfa c t o r y a s h it h e r t o , d e sp it e th e w arn in g I had given in August 1947 I sh a ll be sen d in g you t h e se fig u r e s l a t e r t o keep your l i s t up t o d a t e . I reported by u n derstatem en t, but ad v e r se ly , on th e h ygien ic con d ition s o f th e p la n t ge n e r a lly , ad h er in g s t r i c t l y t o f a c t s . Th is r e p o r t had a ver y sa l u t a r y e f f e c t , even th ough i t u p se t t h e Management v e r y c o n sid e r a b ly . At l e a s t some a c t io n o f r e a so n a b le v igo u r i s b e in g t a k e n . I t i s slow b u t i s gain in g im petu s, and th e a i r a n a ly sis fig u r e s, i f n ot sa t i sfa c t o r y , ar e ver y c o n sid e r a b ly im proved an d a r e now below 1.5 mgms. le a d p er 10 cu b ic m etr es an d in m ost c a se s below 1.0 mgms. le a d p er 10 cu b ic m e t r e s. The prod w i l l con tin u e t o be w ield ed by me. I h ave Mr. Bevan 's f u l l con sen t in w r it in g and v e r b a lly t o p r e ss, b r u t a l l y i f n e c e ssa r y , fo r a h y gie n ic 3t a t e o f a f f a i r s h er e approach in g t h a t Baton Rouge. As I t o ld you our method o f a i r a n a l y si s h er e i s n ot s a t i s f a c t o r y end 1 would be m ost g r a t e fu l i f I cou ld h ave D r . K u r t ' s r e p o r t s on t h e recommended meth od a s e a r l y a s p o ssi b l e , a s our p e o p le h er e ar e in deed in t e r e st e d and w i l l make e v e r y e f f o r t t o p u t our a n a ly sis on a r a t i o n a l b a s i s . As you know, our a l l o y b u ild in g h as n ev er been su b je c t e d t o a i r a n a l y s i s . We a r e now t r y in g w ith a f i e l d k i t , b u t i t i s n ot s a t i s f a c t o r y , t h e r e s u l t s b e in g much low er th an would be a n t ic ip a t e d from th e d egr ee o f fa e c a l e xcr e t io n o f le a d . 0 0 10 0 1 (Con td.) 3^ ri A* &611O0) Ut>#A 1JATK.. ? 7 th J an u ary, 19 4 8 .D -p -2 - Ve h ave n o t y e t r e c e iv e d a copy o f your cor r esp on d en ce on th e s i t u a t i o n in P e t r o Con go. Cop ies fo r U r . R o ffe y and m y self w ere b e in g t yped when I l e f t . /P Th ere h ave r e c e n t ly been a f a i r number o f r e q u e st s from m ed ical p eople n ot con n ected w it h The A sso c ia t e d E t h y l Co. L t d ., fo r an o u t lin e on v a r io u s a sp e c t s o f t e t r a m eth yl l e a d . As you d id r e se a r c h on t h i s I would be g r a t e fu l fo r an y t h in g you cou ld l e t me h ave fo r r e c o r d . i f I h ad a lo n g t a l k w it h D r . San d e r s on st ip p le d c e l l s , and o b t ain e d some o f `"you r s t a i n end b r ou gh t i t b ack h e r e . We h ave n ot t h e same f a c i l i t i e s fo r d r y in g b u t i t i s b e in g accom p lish ed a s q u ic k ly a s p o s si b l e . We h ave n ot been ab le t o g e t t h e same r e s u l t s o r a s good a d e gr e e o f st a i n i n g a s you do in C in c in n a t i, and I 'sh o u ld say th e t em p er atu r e a t which th e s l i d e s ar e t ak en and st a in e d i s ap p r oxim at ely ;1 0 - 1 5 low er t h an in your la b o r a t o r y . I t would seem t h a t ou r r e s u l t s w it h you r method o f st a i n i n g ar e si m i l a r 't o y o u r s, b u t w it h ou r method o f st a i n i n g we s t i l l con t in u e t o h ave a v e r y h igh number o f st ip p l e d c e l l s . I s h a l l be se n d in g some ' s l i d e s t o Dr . San d e r s fo r st a i n i n g and co u n t in g in you r la b o r a t o r y , t o ge t h e r w it h a l i s t sh ow in g our fin d in gs w ith th e m o d ific a t io n o f th e S e l l e r s s t a i n . I was in t h e London O ffic e a few d ays ago and a t t h e C o u r t su ld I n s t i t u t e . P r o fe sso r Dodds in form ed me t h a t he would u n d er t ak e a su r v e y t o d et er m in e fa e c a l e x c r e t io n o f le a d in un exposed in d iv id u a ls. . The si t u a t i o n r e ga r d in g m ed ical c o n su lt a n t s i s f a r from s a t i s f a c t o r y . Th ere i s s t i l l ch aos r e su l t i n g from t h e w ar y e a r s, and t h e s i t u a t i o n i s f a r from c l e a r . I am go in g t o t h e P e r sia n G u lf w it h U r . Pryke in m arch t o se e w h at we can s e t up t h e r e . I t h as been d e cid e d t h a t we v / i l l p r o v id e a l l m ed ical exam in at ion form s fo r m ed ical c o n su lt a n t s w h ich w il l be t h e p r o p e r t y o f t h e Company. I h ave been ask ed t o w r it e a b o o k le t sh ow in g b r i e f l y t h e m ed ical a sp e c t s o f t h e le a d p i c t u r e . T h is w il l be p resen ted t o you fo r e d it in g . I t i s in ten ded t o p r e se n t , under one cover , a gen er al o u t lin e which can be su pplem en ted by l i t e r a t u r e when ou r st o c k s become ad e q u at e . I know you d i s l i k e 'D ig e st ^ ' , b u t a s i t m ust n eed s be pu re p la g ia r ism I h ope you w i l l t r e a t i t k in d ly . The O p e r at io n s Departm en t h ave a lr e a d y p r ep ar ed t h e ir p ic t u r e fo r p r e se n t at io n in one book. I sa d ly m iss my b e e f st e a k s, b u t i t i s n ice t o be home a g a in . I t r u s t t h a t m r s. Rehoe and y o u r se lf ar e in good h e a lt h . P le a se g iv e h er my b e st r e g a r d s. I am su r e you en joyed h avin g K a t ie w it h you o v e r C h r ist m as. W ith kin d r e g a r d s, Yours very sin c e r e ly , . KE" 0 0 10 0 12 E. D avison .