Document nXpzpdjaQ1ELbw1gx8gEEVM8

______ky.w'h News of the w66k j Pvr%~ o Pf j; ,f C" UAL 05092 DIET. WORKPLACE CALLED CARCER FACTORS Saying that "most common cancers are potentially preventable," a Na tional Research Council committee has begun recommending general di etary guidelines to reduce the risk of cancer. Despite their mildness and similarity to guidelines publicized by the National Cancer Institute two and a half years ago (C&EN, Oct. 15, 1979, page 20), the NRC com mittee's report has been criticized instantly. In a separate but topically related development, epidemiologists who study cancer incidence are calling for "continued vigilance in the workplace and environment" to pre vent cancer. They are acting on the basis of a recent analysis which, in part, contradicts another widely dis cussed epidemiologic study that played down the importance of such risk factors for cancer (C&EN, Aug. 17,1981, page 32). The National Research Council, the research arm of the National Academy of Sciences in Washington, D.C., was commissioned by the Na tional Cancer Institute to prepare its report, "Diet, Nutrition, and Can cer.''The ad hoc committee respon sible for that report consisted of 13 scientists from the U.S. and Cana da, including chairman Clifford Grobstein, professor of biological sci ences and public policy at the Uni versity of California, San Diego. The epidemiologists whose study refers to the importance of the workplace and the environment in clude Devra Lee Davis, who recently moved to the Environmental Law Institute in Washington, D.C.; her former colleague at Johns Hopkins University in Baltimore, Kenneth Bridbord; and Marvin Schneiderman, a consultant with Clement Associ ates, also in Washington. The principal trend to which Davis and her colleagues wish to direct scrutiny is that of increasing cancer deaths among older men in the U.S. These epidemiologists discern an in crease in deaths due to cancer among men between the ages of 45 and 65 in the U.S. However, the trend is opposite for men below the age of 45, they note, with a drop in cancer mortality of about 40% since 1950. Davis also draws attention to in creases during the past severed dec ades of the Dulk manufacture of chemicals that are known to cause cancer in humans, including a dou bling of "synthetic carcinogen pro duction" in the past decade. Any effects of this increased manufacture on cancer incidence, either among workers or in the general populace, won't be known "until the end of the century," she says, adding: `"Those who say we have no prob lem are jumping the gun." Thus she takes issue with a study published last year by British epidemiologists Richard Doll and Richard Peto. They Dietary guktofintt may help reduce cancer risk The Committee on Diet, Nutrition & Cancer of the National Research Coun cil says the foHowIriQ guidelines are "consistent with good nutritional prac tices and likely to reduce the risk of cancer." Moreover, the jdleMnsR ought to be followed in "their entirety" for maximum benefit. Consumption of fats should be reduced from tie current level of about 40% to about 30% of total calories in the diet--"a moderate and practical target." The deity (Set should include fruits, especially those rich in vitamin C; veg etables, particularly those rich in caro tene and also members of the mustard family: and whole grains. However, taking of supplements of minor nutri ents found in these foods it not rec ommended, inasmuch as high doses are "potentially toxic." Foods cured or pickled with salt and smoked foods should be "mini mized" In the diet. Contamination of foods with car cinogens "from any source" should continue to be minimized. "Intentional additives" should continue to be eval uated before approval for use In foods. Mutagens m foods should be iden tified and tested for their ability to cause cancer. Where "teasibie end prudent," mutagens should be "re moved" or their levels "minimized." Any drinking of alcohol, particu larly by smokers, should be done "In moderation." concluded that cigarette smoking could account for the only discerni ble general increase in cancer mor tality. Davis says that chemical exposure, infectious disease inci dence, and nutrition also must con tinue to be scrutinized. A wide group of experts, includ ing Doll and Peto, agree that nutri tional factors probably play an im portant role in cancer. The NRC committee also agrees, but says "pre cise estimates of diet's contribution are not yet possible." Nonetheless, says chairman Grob stein, "We recognize we should try to put what we learn to use as soon as possible. By controlling what we eat we may prevent such dietary cancers." Thus the NRC committee has formulated rather mild and "inter im" recommendations for the gen eral population. These recommenda tions are explained carefully and qualified cautiously by the commit tee. The committee adds an even more general caveat: "It is not now possible, and may never be possible, to specify a diet that protects all people against all forms of cancer." The critics of the committee's guidelines are arguing that it may not be possible to specify a diet that protects against any form of cancer. The most vehement critics perhaps are the meat suppliers. Representa tives of the American Meat Insti tute and the National Meat Associ ation, both headquartered in Wash ington, D.C., greeted visitors to the NkC press conference with state ments offering instant criticism of the cancer-diet report. That criticism also draws atten tion to inconsistencies within NRC, and in particular to the stance taken by NRC's Food & Nutrition Board two years ago regarding dietary guidelines (C&EN, June 2, 1980, page 6). Board member Robert E. Olson, a biochemist at St Louis Uni versity school of medicine and a principal author of that FNB report, also is critical of the new NRC re port, calling it ``premature. My basic philosophy is don't make public health recommendations unless you're sure of a benefit," he says. Grobstein defends the NRC re port, saying: "I don't thnk we're pushing any unproven theories." 4 CAEN June 21. 1982 CURRENT REPORT 91 URL 05093 means of limiting exposure, arguing that it has been docu mented that personal protective equipment "is not less expensive." Health Layoffs Interpreted Interpreting the recent dismissals of four senior health officials by companies which he characterized as "not at the top of the heap in statesmanlike business operations," Corn argued that they were laid off because they simply attempt ed to respond to regulations rather than "selling" the posi tive gains of their programs. "You can't build a program on responding to regulations, because when the regulations disappear, as they are now, the program does too," he said. "The aim should be long term responsiveness to the health needs of workers." Corn reported that more than 300 industrial hygienists applied for the some 50 job openings posted at the American Industrial Hygiene Conference, held earlier this month. With the economy in recession, he said, companies are not luring, but the responsible ones "aren't firing, either." Sheldon Samuels, safety and health director of the AFLCIO Industrial Union Department, argued at the meeting that labor unions have demonstrated their commitment to worker protection by leaving their safety and health pro grams intact during general staff cutbacks prompted by the recession. Labor unions now employ 65 permanent, full-time safety and health professionals, Samuels said, up from only four when he began in his position in 1971. None of these is in danger of being laid off, he stated. In addition, some 200 union safety and health positions are funded by OSHA New Directions and other government grants. Labor-Management Committees Samuels questioned the Reagan Administration's commit ment to labor-management cooperation, contending that its withdrawal of the walkaround pay regulation and current efforts to limit worker access to company-held health data demonstrate an unwillingness to promote "two-way'' cooperation. "No labor-management committee can be successful without equal access to data and education and training (of committee members)," he asserted. "In a democratic soci ety. you cannot have a mandated labor-management com mittee that preserves management prerogatives." Neil V. Maresca, environmental health training coordina tor for the International Lead Zinc Research Organisation, Inc., also addressed this theme, maintaining that employers and workers must be trained in group problem-solving techniques if a labor-management committee is to be successful. Describing his experience working with a St. Joe Lead Company/Lead Industries Association joint committee sys tem at the company's Herculaneum Smelter, Maresca en dorsed a "team approach" in which traditional adversarial relationships are gradually broken down. The project was funded by the U.S. Labor Department. Remarking that "management is used to giving instruc tions," Maresca recommended that committee members "learn how to listen and how not to dictate solutions to a group." Projects that do not train members in group deci sionmaking, he said, result either in "anarchy" or "revert to traditional adversarial relationships." The greatest problem with worker attitudes is the poten tial for "apathy, oegativism. and distrust of anything the company tries to do," the training specialist stated. Follow up is important to counter these, Maresca argued, wanting that employees will lose faith if they do not see action taken on their suggestions. Results also help to combat apathy, he said. In the St. Joe project, blood-lead levels, grievances, and absenteeism de clined, while morale and productivity rose, he reported. Publication Available Announced at the seminar was the publication of a case study, How OSHA Enforces the Low: The Effectiveness of the Occupational Safety and Health Administration in Protecting Workers in the Copper Smelting Industry. Written by Sophie Weber, it includes commentaries by Com of Johns Hopkins and Frank Goldsmith of the Cornell Uni versity School of Industrial and Labor Relations. The report was published by the sponsors of the seminar, INFORM, Inc., a public policy research group that studies the impact of business activity on the environment, the workplace, and consumers. It grew out of a 1979 research project on safety and health in the copper smelting industry. Copies of the OSHA enforcement study are available for 315 from INFORM, 381 Park Ave. South, New York, N Y. 10016; telephone (212) 689-4040. A full publications list may be requested, the group noted. Carcinogens STUDY FIND8 RISE IN JOB-LINKED CANCER AMONG OLDER MEN; GREATER CAUTION URGED Cancer deaths among men under 45 years of age declined between 1968 and 1978, but cancer incidence and mortality of the types linked to occupational exposure to chemicals and cigarette smoking rose among men over 45 and in creased sharply among men over 65, according to an analy sis published June 11. Although the authors of the study acknowledged the diffi culty of drawing direct causative links between chemical exposures and cancer, in their conclusion they urged "cau tion and vigilance." They pointed to a doubling in production of synthetic organic carcinogens during the decade studied and warned that the health effects of this growth "are not likely to be fully expressed before the end of this century." The role of toxic chemicals in cancer causation "remains a matter of speculation that may never be simply resolved," the authors stated. They backed the maintenance of general controls, however, saying they may improve public health in unforeseen ways by countering other adverse health effects not now associated definitively with chemicals. "The safer use of toxic chemicals in industrial societies may improve public health in the same way that better water supplies, sanitation, working and housing conditions, and nutrition did in the latter half of the nineteenth cen tury," they argued. The article. "Cancer Prevention: Assessing Causes, Expo sures, and Recent Trends in Mortality for U.S. Males, 19681978" appeared in the journal Teratogenesis. Carcino genesis, and Mutagenesis. It was written by Devra Lee Davis of Johns Hopkins University and the Environmental Law Institute, Kenneth Bridbord of the National Institute for Occupational Safety and Health, and Marvin Schneiderman of Clement Associates, Inc. DoO-Peto Differences Cited In presenting the findings at a June 10 Environmental Law Institute seminar, Davis pointed out that her group's conclusions differ as a result of methodology from those reported last year by Sir Richard Doll and Richard Peto 6-24-82 Occupations Safety A HaaMi ffeportar OMS-8237/82/S00.50 92 OCCUPATIONAL SAFETY & HEALTH REPORTER (Current Report. May 13, p. 1027). Doll amt Peto's argument -- that U S. cancer mortality had not increased generally except for a rise attributed to cigarette smoking -- was based on their decision to study only men under 65, a choice made in order to avoid diagnostic bias that can occur when studying older groups, Davis said. "Given the marked reduction in cancer mortality for men from 35 to 44, analyses of men under 65 will tend to reflect this improvement in mortality and exclude effects in work ers who have had longer industrial exposures to workplace hazards," the researchers stated in the article. Along with the longer exposure period for the older men, Davis noted, poorer diets seen in past decades may have affected the results, since diet has been demonstrated to be a factor in resisting cancer. In addition, sbe pointed out that cigarette consumption was higher in the past, with ciga rettes that were higher in tar and nicotine. A decrease in infectious diseases also may have led to reduced cancer among younger men, according to the study, because there may have been less exposure to viruses that can both initiate and promote cancers by damaging the body's immune system. Per capita exposure to industrial chemicals also has decreased in recent years, it noted, due to automation of production processes and the growth of the white-collar workforce. Another factor cited was the lessen ing use of heavy metal carcinogens such as lead and arsenic. Comments during the seminar centered on the study's use of synthetic organic chemical production as a measure of future cancer incidence and on tbe use of cancer as a measurement of the risk of chronic health effects from chemical exposure. John Higginson, former director of tbe International Agency for Research on Cancer, recommended that work place studies look beyond cancer for what may be worse exposure hazards, such as cardiovascular, neurotoxic, renal, psychophysical, and premature aging ailments. Sanford Gaines, assistant general counsel of tbe Chemical Manufacturers Association, questioned whether the study had actually linked a cancer increase to chemical produc tion. citing tbe many data qualifications used by the re searchers. Sheldon Samuels of the AFL-CIO Industrial Union Department pointed to lingering dangers of heavy metal carcinogens even after their production has declined, saying that they may affect cancer mortality for decades after tbeir first use. Mow 08HA REVISES INTERPRETATIONS OF AMENDMENT IN FIELD MEMORANDUM The Occupational Safety and Health Administration May 19 issued a memorandum to all regional administrators rescinding and revising some interpretations of the agency's hearing conservation rules that were detailed in an earlier memorandum issued in March. These revisions concern follow-up procedures for audio metric testing programs, requirements to report hearing losses on the OSHA Form 200, the acceptance of old audiometric baseline data, monitoring requirements, tbe determi nation of the "action level" for employees working longer or less than eight hours, the definition of significant threshold shift, and the use of hearing protectors prior to baseline testing. The updated memorandum is necessary because the March interpretations "were not properly coordinated," John Miles. OSHA field coordinator and author of the new memorandum, told the regional administrators in a cover letter. He said that "as a result instructions were included which were either incorrect or are premature on the basis of the current rulemaking proceedings on tbe hearing conser vation amendment." Referral end Testing In the March memorandum (Current Report, March 18. p. 828), the agency clarified 1910.95(jX8)(ivXa) to specify that the time period by which employers must inform employees in writing of the existence of a significant threshold sbift is 21 calendar days. As in tbe earlier memorandum, the agency still says that for companies with in-house testing capabilities, the deter mination of tbe STS can occur at the time of testing or at the time the annual audiogram is compared to the baseline. In cases where companies send tbeir test results to a profes sional reviewer, the determination occurs when the employ er receives the results of the review. However, the new memorandum includes an additional statement that there may be a few circumstances where there may be justification for not meeting the 21 calendar day limit The new memorandum instructs compliance offi cers not to cite "where the employer is taking reasonable steps to ensure notification and has kept the employee and/or employee representative informed of the situation." OSHA Form 200 As in tbe earlier memorandum, the agency still maintains that under its recordkeeping regulations at 29 CFR 1904.2, work-related noise-induced bearing loss must be recorded on the OSHA 200 form. The new memorandum tells enforcement personnel gen erally to consider a citation when an employer fails to report on the OSHA 200 form a hearing loss equal to or greater than 20 dB at any test frequency, and where that employee's time-weighted average noise exposure is 85 dB or greater. Tbe agency stated further that if the employee was referred to a physician and it was determined that tbe lorn was not work-related, then the loss does not have to be reported. Tbe memorandum noted that tbe provision for recording a significant threshold shift on tbe OSHA form 200 is currently stayed and is being reconsidered. Hbrendfethered* AucSogreme In the new memorandum, the agency has deleted the requirement in its March interpretation that in order for old baseline audiograms to be acceptable they must have been administered by a trained technician, taken at the test frequencies of 500,1000, 2000, 3000, 4000, and 6000 Hertz, in a reasonably quiet room and with calibrated equipment, and that tbe old audiogram showing the lowest thresholds should be selected as the baseline. Miles told the regional administrators that this interpreta tion provided "too much detail," which he said is inappropri ate in light of on-going rulemaking proceedings. Tbe new memorandum does not detail requirements for showing that tbe old "grandfathered" audiograms reflect reasonable compliance with the audipmetric test require ments of the amendment It also states that if the employer wishes, new baselines can be established. Monitoring Requirements Miles said tbe old enforcement instructions regarding monitoring requirements in cases where employers decide to include all employees, regardless of their exposure, in the URL 05094 6-24-82 Copyright C 1M2 by Ttw Bureau of National Attain, Inc. 008S-3237/B2/M0.90 JU ^ /' 414 CHEMICAL REGULATION REPORTER UBl 05095 Tbe same problems exist with respect to the PCB-specific provisions of the Connecticut statute, according to EPA. The state also failed to submit any documentation con* cerning interstate burdens that might result if Connecticut law was substituted for TSCA, the agency said. If storage or disposal requirements by tbe state were significantly differ ent from federal reguations or the regulations of nearby states, "serious obstacles lo interstate commerce could re sult from companies having to transport wastes across state lines," EPA said. Connecticut's interest in exemption from TSCA stemmed from an attempt by a company to warehouse waste PCBs in a Connecticut town. The move was opposed by tbe local community on up to the state level, but the warehouse complied with federal rules and won a permit The state then applied for an exemption from tbe PCB provisions of the federal regulations so it could impose its own controls. Reporting PRODUCTION CONFIDENTIALITY TO BE PROTECTED AS VOLUME TOTALS ARE COMPILED, AGENCY SAYS Total production statistics for chemicals on the Toxic Substances Control Act Chemical Inventory may be released under a scheme which would place in broad production categories those chemicals for which such data have been claimed confidential, according to the Environmental Pro tection Agency. The plan, termed the "roll up" method by the agency, was developed to provide the public with general aggregated data on the chemicals while still protecting company claims of confidentiality. About 40 percent of the 54,369 chemicals repeated to tbe inventory bad one or more submitters who made claims of confidentiality for production ranges, according to tbe June 23 agency notice (47 FR 27073). Of those, 15,422 substances had only one claim of confidentiality, 3,000 had two claims, and 3,010 had three or more claims. Under the roll up method, chemicals on which manufac turers claimed confidentiality would be placed in one of tbe following broad categories: Range 1 -- 0 to 1 million pounds; Range 2--1 million to 100 million lbs.; Range 3 -- 100 million to 1 billion lbs.; and Range 4 -- 1 billion lbs. and above In a limited number of situations where a chemical's production range overlaps tbe upper or lower bounds of the broad range, tbe inventory chemical will be placed in an expanded range based on tbe calculated total production, EPA explained. Non Confidential Production The agency said that when originally reporting tbe chemi cals for tbe inventory, firms which did not claim production data confidential placed the substances within one of tbe following 11 categories: N -- none; 0 -- 0 to 1,000 lbs.; 1 - 1,000 to 10.000 lbs.; 2 - 10,000 to 100,000 lbs.; 5 -- 100,000 to 1 million lbs.; 4 -- 1 million to 10 million lbs.; 5 -- 10 million to SO million lbs.; 6 -- 50 million to 100 million lbs.; 7 -- 100 million to 500 million lbs.; 0 -- 500 million to 1 billion lbs.; and 0 -- over 1 billion lbs. Public comments on the roll up method of reporting confidential production totals will be accepted until Aug. 23 and should bear the identification number OPTS-80012. The comments should be sent to Document Control Officer (TS703), Office of Pesticides and Toxic Substances, EPA, Room E-409, 401 M St. S.W., Washington, D C. 20460. For more information, contact the Industry Assistance Office at the above address or call (800) 424-9065 toll free, or 544-1404 in the Washington, D.C. area. Reporting STANDARD OIL REPORT8 KIDNEY DAMAGE IN INHALATION STUDIES ON NAPHTHA STREAMS Inhalation of selected naphtha streams resulted in degen erative kidney effects in male test animals, according to preliminary data submitted by Standard Oil Company of Indiana to the Environmental Protection Agency. Tbe firm submitted the data under Section 8(e) of the Toxic Substances Control Act, which requires firms to notify tbe agency when learning of data that shows a chemical to cause a health hazard. The studies were performed by tbe Illinois Institute of Technology Research Institute for the oil firm. According to the notice, all male rats exposed to fullrange alkylate naphtha in concentrations of 1.5 milligrams per liter to 15 mg/1 suffered from degeneration or necrosis -' of the kidneys, while female test animals suffered no health effects. Inhalation studies on a hydrocarbon blend containing ap proximately 22 percent full-range alkylate naphtha resulted in kidney tubular degeneration or necrosis for five of the 10 male test animals exposed to 15 mg/1, seven of tbe 10 exposed to 1.5 mg/1 and me of 10 exposed to 0.5 mg/1. After a me month recovery period, degeneration was still noted in most of tbe subjects experiencing tbe health effects. Female rats experienced no kidney damage. A .similar inhalation study conducted on light catalytic cracked naphtha showed "no evidence of any treatmentrelated lesions," tbe company's report said. Another study on light straight ran naphtha will be repeated due to respira tory problem experienced by all animals, including con trols, it added. Based on the preliminary data, tbe firm noted "there is reason to believe that certain naphtha streams may be responsible for tbe degenerative kidney effects seen in male rata." Tbe American Petroleum Institute has been asked to study tbe substance. Standard Oil noted that tbe test findings are similar to those reported by Exxon Corp. and Atlantic Richfield Co.in earlier Section 8(e) submissions which noted kidney effects resulting from exposure to a light alkylate naphtha and to unleaded gasoline. leheMng UNIONS PLEDGE MORE ACTIVITY IN STATES; TRADE SECRETS. HAZARD EVALUATION DEBATED Tbe AFL-CIO and member unions will continue to seek state and local chemical labeling laws "as long as we can and until such time as we see a strong federal standard," tbe labor federation's safety and health director, George H.R. Taylor, stated during Occupational Safety and Health Ad ministration ralemaking bearings June 16. Asked by Bill Leathers, a representative of Dow Chemical Co., what the AFL-CIO'i position on state laws would be i 6-2S-S2 Copyright C 1M2 by Tha Buroeu of MaUnnol Allah*, tne. OM-7fT/tt/SOO.SO Letters / whenever ready, the water was dispensed into gallon jugs and consumed freely. It was also used to prepare mik from the (fried powder. No incidence ot gastrointestinal upset was experi enced by any member of the family consisting of four males ages nine. 14.15.43 and two fe males ages 12 and 43 (none of whom had been to Mexico before). It is not recommended that ozone be used in murky water or in suspect soft drinks We used only clear water and used the ozone as a final treatment. It is felt that neither the output of ozone nor the flow rale is critical because so much is lost to the atmosphere. As long as the bubbling ac tion was Hve>y and an excess of o2one was very evident by smell. 10 minutes contact was ade quate. Robert T. Ansefmi Denver Chemically induced cancers SIR: Under the News of the Week (CAEN. June 21.1961, page 4) you ptiHished an article "Diet, workplace called cancer factors." which pub licized the National Research Council com mittee's newly recommended "dietary guide lines" devised to help reduce cancer risks. The article goes on to report that the guide lines had been criticized Instantly by such epi demiologists as Devra Lee Davis, who calls for continued vigilance in the workplace and envi ronment and fraws attention to increases dtring the past several decades of the bulk manufac ture of chemicals that are known to cause can cer in humans, including a doubling of synthetic carcinogen production in the pest decade. Davis is also reported to take issue with the study "The Causes of Cancer" by the British epidemiolo gists Richard Doll and Richard Peto, who con cluded that cigarette smoking could account tor the only discernible general increase in cancer mortality. The divergent views of such reputable epi demiologists cast a shadow an the tenstsof tier science, in their above-mentioned study. Doll and Peto comment on this situation. They ob serve that "epidemiology has at present an wv deservedly tow reputation among paopla who hava first artificially Hmttad fhemaefvas to wondering vrftich environmental pollutants to reetoct and who toan find that almost none oMhe few thousand chemicals tiey are worried about have been adequately studied by epidemiolo gists. This is, however, to condemn epidemiology for fading to achieve ends that it does not have. Epidemiology starts not with the 10,000 chem icals poffuttoQ e particular city, but with the 10.000 annual cancer deaths In that city, and it fries to determine the major causes of these actual deaths." There are several recent studies that proceed from mortality or mortidtty statistics. Significant tor an appraisal ol the threat of chemicals are: 1. "Epidemiologic Study of Refinery and Chemical Plant Workers," Journal of Occupa tional Medicine. Vol. 24. No. 3. March 1982 In this survey, the mortality experience of 8666 regular workers at Exxon's Baton Rouge refinery and chemical plant was determined. Mortality from all causes of death was lower than ex pected when eompered with that ol the O.S. population of similar sex, age, and raca. 2. "A Retrospective Cohort Study of Mortality and Cancer Incidence Among Chemists." jbtma/ of Occupational Medicine, Voi. 23, No. 7. July, 1981. The study examines mortality and cancer incidence among $686 men and 75 women who were employed as chemists in 1959. During the period 1964 to 1977. they ex perienced lower overall mortality than other salaried employees of the chemical company. 3. "Cancer incidence to the Love Canal Araa." Science. 212, page 404, Jina 19.1981: Data from the New York Cancer Registry show no evidence for higher cancer rates associated with residence near the Love Canal toxic waste burial site in comparison with the entire state outside New York City. These findings weaken the thesis of the rise of chemically induced cancers so that Its threat should not detract from the NRC committee's recent report. Latmbe, Pa. Ernest W. Vokmann URL 05096 INDEX TO ADVERTISERS IN THIS ISSUE Commission Dos Communantos Enropoennos ....................................... 24 S.A. Agence Havas Beige n.u. Exxon Company U&A.................... 12-13 McCann-Erickson, Ihc. Getty Kafininc A Marketing .......... IBC Advertising Incorporated Molecular Design ............................. OBC Humpal, LsftwLch A Sinn, Inc. Ado. Phillips Chemical Company............. IFC Barickman Adv. Inc. Quests) ..................................................... 25 Scientific Marketing Services, Inc. Verlag Chemie International ........... 122 Virginia Chemicals ................................. 7 VonSont DugdoU A Co., Inc. DIRECTORIES Chemical Exchange............................. 120 Claasiflei Advertising................. 114-110 Equipment Mart....................................129 Technical Services................................120 AdorTiry Managerne*! foi re Awcm CMm^1 Socaly Publication CENTCOM. LTD Thoms*- N. ). Knerwer, President; James A Byrne. Vice President; Alfred L. Grecorv, ^ Yire President; Clay S. Holden. Vice Presi dHReoonabtde:rStBo1e,un. Vtihao,mePpin.eOlW,. VB.iocJxeonP2e3rse1,,siVWdiecenestt;Pp2orSertSs,iydClevonantn; necticut 068W1 (Area Code 203) 226-7131. ADVERTISING SALKS MANAGER Benjamin W. Jones sates acaacsfMTATtvts nsMill nn . .MOTH <Sk*iMongon. centcom. lm Tenenem 203-226-7131 MM, HA . Waflar M (Skip) uxpn. CENTCOM. Ltd Telephone 203-226-7131 CMcf a (frown H KreiChor. CENTCOM Ltd 540 Frontage *0 . NonMieid. I 50093 Telephone 312441-5393 CtrretenA. OH . .Osn*i j Cook. CENTCOM. Ltd it Chech Si. Boro*. OH 44017 Telephone 215-234 1333 Oa9ae. TX Anthony j Eagan. Dean A Baldwin CENTCOM Lid Tolaphone 215-567-9556. HuCkle A Associates. 1100 Hu no i Suae 101. Nmmoa. Tx 77059 Telephone 713-333-1650 Beaver.CO CleyHolden.CENTCOM Ltd Telephone 213-325-1503 Havaian, TX Anmony j Eagan Boon a Bene*. CENTCOM. Ltd Telephone 215-557-5556. Hueie 6 Associates 1100 New no 1. Sunt 104 Houston. TX 77059 Telephone 713-333-1950 Lm Angelet, CA Cley Homen. CENTCOM Ltd 3i2 Pacific COM! Hghewy. Suae 200. Torranee. CA 90505 Telephone 213-325-1903 NewVerVHY AifiedL (eegory Anthony J sg*r Waller H iShipl Monger Tnoma* Cere*. CENTCOM Ltd 50 East 42nd Si New York. NY lO'65Telephcoe 212-972-9550 PMedefrMa. 9a . . Seryanvri w jones Arrihony j Eagan. Frank Patton. CENTCOM. Ltd GS6 Bunding Sutia 425. i Beenorn Ave Beta Cynwyd. Ps 19004 Telephone 215-567-9566 Swi PnaOBCO, CA P*MM Butts CENTCOM. L Suite 112, 1499 Seymore lAfrywey. BtrUngeme. CA 94010 Telephono 415-692-1219 WiHpert, CT Waller h (Skip) Mongon. CENTCOM Lid 25 Sylvan Road Soum. P.O Bo> 23i. Westport. CT 05661 Telephone 203-226-7131 um--KHsmwi LnueHIn, tapinil . . TecftnomedH. Ltd . . .c/o meongmici UP-.31 OldBeeei. AMnUnder Lyne, UncwNre. Engtond Telephone 061-S0BO025 BeadHs. BnglwM . . .TeehnemedM. ud. . . .Wood Comae, luM Row. Amdtog N010 OQE BvksNre, England Telephone 0734-343302 CemmeMai Europe AnWe Jemar. RueMMHr i. 4600 Vevie Beigwn Telephone 067-22-53-95 Teie> no 49263 Tokyo. Japan . Sh^eoAok. imemanonai Media Pep reaantahvas Lid . 2-29. Toranomon i-Cnrome M-na tchu Tokyo 105 Jepen Telephone 502-0656 PRODUCTION DEPARTMENT Production Director Joseph P. SLenta Production Assistant* Barbara Aufderheide Classified Advertising Geri Anastasia Aug. 2, 1982 C&EN 121