Document n9DEo9Dm0yVa4dnGBq2Bg7mV8

March l, 1963 Mr. D. N. Griffiths Purchasing Department Delco-rtssy Division Gansrsl Motors Corporation Anderson, Indiana Doar Mr. Griffiths I have received your card and memeographed Insert entitled "Hasardous Materials" that accompanied jour order for > gallons of Aroclor 1232. Our bulletin covering this com pound will answer the questions posed In your mtmeographed fore with the exoeptlon of the No. 1 question concerning a toxicity rating. As you know, Aroclor 1232 la a chlorinated biphenyl ohlorlnated to j2 by weight. In the Sax book mentioned In your note you will find chiorlneted diphenyls, under thla heeding appesra the toxicity rating for this compound by the author of this book. I have examined your very brief card concerning the hesards associated with handling Aroclor 1232 and find It very diffi cult to fill out. I am afraid It would be better if we dis cussed this material and the conditions of hendling which would, of course, dlctste tbs answer to the queatlona on the card. Aroclor 1232 has so oral LD50 In rats of 4470 Milligrams par kilogram which ws rats slightly toxic by this routs. The material has s alnlmum lethal doss by skin absorption In rabbits of greater than 1260 milligrams par kilogram and lass than 2000 milligrams per kilogram, these data would again classify as slightly toxlo by this routs of administration. By evaluation of those animal data and aany years experience in the use of Aroclors as a hast transfer medium, ws Interpret the hasard connected with handling this material as follows 1 (1) The dally use of this product In this appli cation presents no hsssrds whan one rollowe tha recommended precautions such as the use of the medium in a scmpletely saalsd system where there will be no leakage of liquid or the vapore when the materiel la hasted. MONS 090347 Nr. D. N. Griffiths - Pi{t a - March 1, 1963 (3) the loaa of fluid at a high temperature or by being sprayed onto heated aurfacee (aa the result of a broken line) preeents a hasard to humans no acre critical than with other type fluids. In either event, the vapors or decom posed products would be so Irritating that work man would not remain In the contamlneted atnosphere without respirator* or gas masks. In thoss Instances where breaks have occurred, exposure to the workers long enough to shut ofr the system and svacuat# the premises has not resulted In any 111 effects. (3) Skin contact with Aroclor 12J2 at normal temperatures does not presont a hasard In terms of lAMSdlate or subsequent syatemla effects If normal personal hygiene practises are followed. In other words. If there Is massive skin exposure, workmen should, within a reasonable time, remove contaminated clothing and bathe thoroughly. (4) Repeated or prolonged dally skin contact should be avoided In order to prevent possible Irritation to the akin and possible systemic effects. Again, normal personal hygiene should suffice aa long as It is understood that workman must not amsar the liquid on the skin and allow It to remain, These recosmandatlons Indicate that the compound la hasardous only when It Is heated where sufficient of the material can vaporise to constitute an Inhalation hazard. There has been no MAC (maximum allowable concentration) established for Aroelor 1232. However, Aroclor 1242 which le biphenyl chlori nated to 42d by weight chlorine has an MAC of 1 milligram per cubic mater. If I can be of any further help, please 1st me know. Sincerely, JTOldf Jack T. Garrett, Manager Industrial Hygiene Medical Department MOMS 090348