Document mpNw3BXJOzRXQwrKxavygQdKQ
FILE NAME State of the Art Literature SAL
DATE 1966 DOC SAL074
DOCUMENT DESCRIPTION Report - Documentation of Threshold Limit Values
2
Documentation of
% Threshold Limit Values
REVISED EDITION 223%
COMMITTEE
ON
.
THRESHOLD
=
LIMIT
VALUES
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44te Free C44 oases 4440 9400 F740 4s4er C4Ce 7900
Copies of this publication may be obtained from
4
American
Secretary
Conference of Governmental Industrial
1014 Broadway Cincinnati Ohio 45202
Hygienists
Price per copy 4.50
Make checks payable to American Conference of Governmental Industrial Hygienists
Copyright 1966
by American Conference of Governmental
Industrial Hygienists
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References References
-
- Henderson Y. Haggard N.W Noxious Gases Reinhold Publishing Co. N.Y. 1943
Nmi
Nau C.A South Med J. 41 341 1948
Nmi Elkins H.B Chemistry ofIndustrial Toxicology Wiley & Sons N.Y. 1959
4. Bulmer F.M.R. et al J. Ind Hyg & Tox 22 111 1940
ASBESTOS
5 mppcf
Asbestos is a generic term applying to a number of mineral silicates that
incombustible in air and can be separated into filaments The most
are
industry is chrysotile a magnesium silicate from
widely used in
amosite
an
iron magnesium silicate
crocidolite
serpentine a sodium
Other types
include
calcium magnesium silicate and anthophyllite also
fron silicate tremolite
iron
a
an
magnesium silicate
Miller and Sayers 1 showed that intraperitoneal injection of
tile and crocidolite in guinea pigs produced the reaction of
amosite chryso-
et al
2
confirmed this
for short
fibers
under 3
an inert dust but observed
Vorwald
produced a fibrous reaction Continuing unpublished work
that long fibers
by Gardner these workers
than chemical action Asbestos dust containing 0.6 per cent fibers
microns
in
concentrations
of
138
mppcf
or
0.8 million
long
longer
fibers
than
10
was capable of producing experimental asbestosis in
per cu ft
was 6.7 per cent fibers over 10
guinea pigs When the concentration
microns 40 mppcf equivalent to 2.7 million long
fibers per cu ft the reaction developed in approximately half the time
3,4,5,6,7,8,9,10,11 That exposure to asbestos is associated with
development of a potentially dis-
abling pneumoconiosis in man has been amply demonstrated by industrial experience
The present threshold limit was recommended by Dreessen et
al 8 after study of 541 employees in three asbestos textile tile Only three doubtful cases of pneumoconiosis were found in
plants
those
using
chryso-
dust concentrations under 5 mppcf whereas numerous marked
exposed to
above
5
mppcf
Counts
were
from
collected
samples
in
cases were found
ethyl alcohol
tilled water Both fibrous and nonfibrous particles were
and dis-
greatly predominated While chemical
counted but the latter
analyses of collected samples of borne dust
corresponded to those of settled dust samples it is believed that dust
particulates by conventional methods can be
counts of
expected to give only an indirect measure
of the risk of asbestosis because of the great relative importance of long fibers
References
1. Miller J.W. Sayers R.R Pub Health Rep 56 264 1941
inm inm
Vorwald A.J. Durkan T.M. Pratt P.C Arch Ind Hyg 3 1 1951
Merewether E.R.A
J.
Ind
Hyg 12
198-239
Pneumoconiosis
1930 Pneumoconiosis
1926-1938 Vol I p 128
Abstracts
A. Wood W.B. Gloyne S.R Lancet Dec. 22 1934 pp 1383-1385 ^'n FIunldtoBnulWl.B4.2 Dooley A. Matthews J.L. Houtz R.L Penn Dept. Labor and
Dooley 6 Lanza A.J. McConnell W.J. Fehnel J.W Pub Health
7 Donnelly .: J. Ind Hyg & Tox 18 222 1936
Rep 50 1 1935
8 Dreessen W.C. Dallavalle J.W. Edwards T.I. Miller J.M.
Pub Health Bull No. 241 Washington D.C. 1938
Sayers R.R
9 Lynch .: Arch Ind Health 11 185 1955
10. Smith K.H Arch Ind Health 12 198
1955 :)
11. Cartier .: Arch Ind Health II 204 1955
15
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