Document mkjRjLNYra49661QDQb3mmj4

Toxicit 3820( TOXICITY TO AQUATIC PLANTS (E.G.,ALGAE) TEST SUBSTANCE Identity:Perfluorooctanesulfonatmea;y alsobe referredtoas PFOS or FC-95 oras partofthe mixed productFM-3820 (see Remarks). (1-Octanesulfoniaccid,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-p,otassiumsalt,CAS # 2795-39-3) Remarks: The testsample isFM-3820, a mixtureofthe testsubstance in diethyleneglycolbutyletherand water (approximately24-28% test substance indiethyleneglycolbutyletherand water).Calculationwsere made toadjusttestvaluesusingthe upper limictoncentrationofthetest substance(28%) inthe testsample and no adjustmentwas made forthe presence ofthe diethyleneglycolbutyletherorwater when noted below. These calculationasssumed thatalltoxicitwyas due tothe presence of the Perfluorooctanesulfonastuebstance. METHOD Method: OECD 201 Test: Staticacute GLP: No Year completed: 1991 Species: Selenastrumcapricomutum Source: Originallfyrom the CultureCollectioonfAlgae atthe Universitoyf Texas atAustin,maintainedinculturemedium atEnviroSystems Division, Resource Analysts,Inc.,Hampton, NH. Analyticalmonitoring:Temperature and pH Element basis: Growth rate Exposure period:96-hours Startdate: 4/29/91 End date: 5/3/91 Test organisms laboratoryculture:Algae cultureshad been actively growing insterileenrichedmedia identicatlo media used forthe testand maintainedattestconditions. Test Conditions: Test temperature range: 23.0 - 23.1*C Dilutionwater:Syntheticmedia preparedwithsterildeeionized water accordingto U.S.-EPA standard,1978. Dilutionwater source: Not noted. Stock and testsolutionpreparation:A primarystocksolution was preparedinalgalmedium ata concentrationof 1000 mg/L. The primarystocksolutiownas proportionaldliylutedwithalgal medium topreparethefiveadditionatlestconcentrationdsirectliyn the testvessels. Exposure vessels:250 mL glassErienmeyerflaskscapped with invertedglassbeakers and containing100 mL oftestsolution. Agitation:Shaken continuously Number of replicatest:hree Initiaallgalcellloading:1.0 X 104 cells/mL Number of concentrations:Fiveplusa negativecontrol Water chemistry: pH range (0- 96 hours) 8.0- 10.3 (controelxposure) 7.2- 8.1 (1000mg/L exposure) Test temperaturerange (0- 96 hours) 23.0 - 23.1OC Lightlevels:(0- 96 hours) 40 uEin/seC/M2from continuouscool-white fluorescentlighting RESULTS Nominal concentrations:Bk control6,2.5,125,250, 500,and mg/L. Test Sample Element value: 24-hourEC5o (growthrate)= <62.5mg/L (Clnotcalculable) 48-hourEC50 (growthrate)= 707 (500-1000)mg/L 72-hourEC50 (growthrate)= 284 (249-325)mg/L 96-hourEC50 (growthrate)= 255 (222-293)mg/L 96-hourNOEC (growthrate)= 125 mg/L 1000 PerfluorooctanesulfonatceoncentrationadjustedElement value: 24-hourEC50 (growthrate)= <17.5 mg/L 48-hour EC50 (growthrate)= 198 mg/L 72-hourEC50 (growthrate)= 80 mg/L 96-hourEC50 (growthrate)= 71 mg/L 96-hourNOEC (growthrate)= 35 mg/L Allelement valuesbased on nominalconcentrations Statistimceatlhods:EC50 valuewserecalculatuesdingthebinomiaolr moving average method. The NOEC was calculatedusingDunneft'stest. The average specifigcrowthratewas calculateads the naturallogofthe number of cellsper ml at96 hours minus the naturallogofthe number of cellsper mi at0 hours dividedby the exposure period.The percent change from controliscalculatedby subtractintghe sample average specifigcrowth ratefrom the controlaverage specifigcrowth rate,dividing thatvalueby the average specifigcrowth rateinthe controland multiplyintghatvalueby 100. The percentchange from controlwas used to compute EC50 and NOEC values. Control response: Not noted. Mean Growth data: Nominal ConcentrationN,umber of AverageSpecific PercentInhibitivoina mg/L CellspermL GrowthRate(p) Growth Rate Negative 448,000 0.040 -- Control 62.5 198,000 0.031 22 125 281,000 0.035 12 250 221,000 0.032 20 500 12,000 0.002 95 1000 11,000 0.001 98 Observations: The number of algal cells/mlin each test vessel was determinedby means ofdirectmicroscopiccountswitha hemacytometer. Reversibilitoyf Growth InhibitionN:ot noted. CONCLUSIONS The testsubstance 96-hour EC50 and 95% confidenceintervaflor Selenastrum capricomutum was determinedby growth rateto be 255 (222-293)mg/L. The 96-hourNOEC was determinedby Dunneft's proceduretobe 125 mg/L. Ifyou attributaelltoxicittyothe Perfluorooctanesulfonactoemponent of the testsubstance(FM-3820) usingthe 28% upperconcentratiolnimitt,he 96-hourEC50 (growthrate)= 71 mg/L and the 96-hourNOEC (growth rate)= 35 mg/L Submitter3:M Company,EnvironmentLaalboratorPy.,O.Box 33331,St. Paul,Minnesota,55133 DATA QUALITY ReliabilityK:limischranking= 3. The studylacksanalytical measurement oftestsubstance concentrationisnthe testsolutions, determinationofthe mode oftoxicitiyn,sufficiecnhtaracterizationf sample puritya,nd insufficieenxtplanationofobserved anomalies in toxicitryeadings.Additionally,.thwe(ite-updidnot indicattehe test vesselswere sterilea,nd data isfora mixtureand toxicitcyannot be positivelayttributetdoPerfluorooctancesulfonaatsethe diethyleneglycol butylethercould alsocontributteo the toxicity. REFERENCES Thisstudywas conducted atEnviroSystems Division,Resource Analysts, Incorporatedatthe requestofthe3M Company. OTHER Last changed: 5/3/00 Study Title Static Rcute Toxicity of FN 3920 to the Alga, Selenastran copricorautuw Authors Robert L. Boeri Timothy J. Vard Study Completed June, 1991 Performina Laboratory UviroSystess Division Resource knalysts, Incorporated P.O. box 2110 One Lafayette load Hampton. New gaapshire 03942 Page I of IS ROMOM An*ft kr-lbddhMYd MTLFM SMMRT The acute caPric0z'Dutus, is toxicity of FM 3820 to the alga, Selenastrun described in this final report. The test was conducted for 311 Company for 96 hours during April 29 to May 3, 1991, at the Eaviro$ysteas Division of Resource Analysts, Inc. in Hampton, New Hampshire. It was conducted by Jeanne Nagaza, Peter lowalski, Kllen Stanford, Robert Boeri, and Timothy Ward. The test was concentrations of test temperature of 23.OOC. with sterile deionized Light was adjusted to performed under static conditions with five substance and a dilution water control at a mean Tht dilution water was synthetic media prepared water. Flasks were incubated on a rotary shaker. 40 uEin/sec/e with a pbotoperiod of 24 hours light and 0 hours dark. Nominal concentrationsof FN 3820 were: 0 ag/L (control), 62.5 mg/L. 125 mg/L. 2SO ag/L, SOO ng/L, and 1,000 ogIL. Nominal concentrations were used for all calculations. Algae used in the test was from an in-house culture that was maintained under test conditions. Erpmure of algae to the test substance resulted in a 72 hour SCSO 284 mg/L FN 3820 and a no observed effect concentration (NOSC) less than 62.5 ngfl. The 96 hour ECSO and NOEC are 255 mg/L and 12S mg/L, respectively. Page 2 of 15 RowLKS N%at^ kv- &Amcomy K%IFM n. TABLI or SECTION: i Summary TI. Table of Contents III. Index of Tables IV. Introduction V. Methods and Materials VT. Results VTT. References Appendix A. Water Quality Data from Toxicity Test PAGE 2 3 4 5 5 8 12 13 Page 3 of 15 ResoLfAtAe*ft W- SAAkftyOfholpm rri. OF 7lBLzs Table 1. Cheaical characterization of a representative sample of deionized water used to prepare test media for toxicity test Table 2. Growth data from toxicity test Table 3. Percent change from control and average specific growth rate from toxicity test Table 4. Nedian effective concentrations (WSOS) from toxicity test Table A.I. Temperature measured during toxicity test Table A.2. pH measured during toxicity test a PICI 6 9 10 11 14 Page 4 of 15 RamungNc"L bir&-kdcftyd MUFM IV. IMODUCTION This study was sponsored by 3M Company, St. Paul, Minnesota. The objective of the study was to determine the acute toxicity of TH 3920 to a freshwater alga. The report contains sections th.%tdescribe the methods and materials eaployed is the study, and the results of the investigation. The report also t-mtains an appendix that presents the water quality data collected during the test. V. NTRODS JLXD MATERIALS TEST SUBSTANCE: FN 3820 (SoviroSysteas Saaple Nuaber 26961) was delivered to EaviroSysteas an November IS, 1990. It was contained in a 2SO aL glass bottle that was labelled with the followinginforaatiou:'1 2864-6, FK 3820". FN 3820 (a pale yellow liquid) was supplied by 3W Company, 935 Bush Avenue, St. Paul, Minnesota. Prior to use the test material was stored in the dark at rooa teaperature. I reserve saaple (approximately 2.0 grass)-will'be archived at UviroSysteas for a mininua of 10 years. DTLUTRON VATER: Water used for acclimation of test organisms and for all toxicity testing was sterile enriched media (U.S. SPA, 1978) with a pg of pproxiaately B.O. Results of cbesical analysis of a representative :aaple of deionized water used to prepare the aedia are presented in Table 1. TEST ORGMSN-. Algae used for the test was froa a culture originall]r procured from the Culture Collection of Algae at the University of Texas at Austin and delivered to roviroxysteas on April 12, 1990. The identity of the culture was verified using an appropriate taxonomic key. The culture was transferred to sterile eariebed media identicalto media used for this test and aaintained at test coaditions. TOXICITY TESTM: The didlinitive toxicity test was performed during April 29 to May 3. 1991. It is based on procedures of the OECD (1984). The test was conducted at a target teaperature of 22 2*C with five concentrations of test substance and a dilution water control. A 1,000 mg/L stock solution was. prepared -in dilution water. The stock solution was added directly to dilution water contained in the test vessels without the use of a solvent. Noainal concentrations of the test material were: 0 ag/L (control), 62.5 ag/L, 12S mg/L, 2SO ag/L, 500 mg/L, and 1,000 mg/L. Page S of 15 awm=e Nx*ft k-r- S.Ab@ d MUFM Table 1. Chemical cbaracterization of a representative sample of deianized water used to prepare test media for toxicity test Parameter Unit of Measurement Reporting Limit Measured Value orgahocblorine ug/L 2 IFD pesticides Organophosphorus ug/L 0.5 ND pesticides Polycblorinated ug/L 0.5 n biphenyls.-,- Note: ND not detected at or above the reporting linit. Page 6 of 15 Ramum NOW& kv-&Ankiayd MTLFM Algae was randomly and equally distributed among three replic3tes of each treatment at the rate of 10,000 cellsfal. The test was perforued in 250 al glass Erlonstyer flasks that contained 100 al of test -solution. The flasks were capped with inverted glass beakers. Test vessels were randomly arranged on a rotary shaker in an incubator during the 96 hour test (a random numbers table was used to select the location of each vessel). A 24 hour light and 0 hour dark pbotoperiod was maintained with cool-vbite fluorescent lights that provided a light intensity of 40 uEs7sx-2. The number of algal cells/ml in each test vessel was determined visually every 24 boars by means of direct microscopic Counts With a hemacytometer. The VN (Beckman model pgl 12 meter) was determined in each test flask at the beginning and end of the test, and temperature (ASTM mercury thermometer) was measured and recorded daily in the incubator. STATISTICAL METHODS: Results of the toxicity test were interpreted by standard statistical techniques (Stepban, 1933). The binomial or moving average method was used by the author to calculate ECSO values using nominal concentrations of test substance. The NOEC was calculated using Dunnett's test, which includes a parametric one-wa3r analysis of variance (ANOVA). The average specific growth rate was calculatedas the natlral log of the number of cells per al at 96 hours minus the natural log of the number of cells per al at 0 hours divided LOYthe exposure period. The percent change from control is calculated by subtracting the sample average specific growth rate from the control average specific growth rate, dividing that value by the average specific growth rate in the control and multiplying that value by 100. The percent change from control was used to compute ECSO and NOEC values. Page 7 of 15 RaoxamAnaoyfkty-SLt)mdKdnWBIFOM Vi. RLSULTS Biological and water quality data generated by the acute toxicity test are presented in Table 2 and Appendix 1, respectivel3r, and the percent of control and average specific growth rate inforsation is presented in Table 3. The 24, 48, 72. and 96 hour EC50s for algae exposed to FN 3820 are presented in Table 4. The 72 hour SCSO is 294 mg/L. and the 72 hour NOEC is less than 62.5 mg/L TN 3820. The 96 hour ECSO is 2SS mg/T& and the 96 hour NOBC is 125 mg/L. Page 8 of 15 RomLK*Aro*stbLirI-TOM" d LRLFORE Table 2. Grovtb data fro& toxicitytest womilial Concentration (mg/L) rep. 0.0 (control) 62.5 125-250 Soo 1,000 1 2 3 mean 1 2 3 mean 1" 2 3 a:an 2 3 mean 1 2 3 se:n 2 3 mean Number of Cells per Nilliliterx 102 (bour) 0 24 43 72 96 10 26 4S 224 436 10 20 S4 222 426 to 22 56 320 432 10 23 52 2SS 449 10 10 76 ss 222 10 12 53 104 168 10 6 62 120 204 10 9 65 104 198 10 10 66 92 312 10 12 70 106 296 10 10 S4 96 234 10 11 63 9S 281 10 is 54 127 214 10 14 62 130 256 10 22 62 122 194 10 is S9 126 221 10 16 36 26 10 10 12 34 44 22 10 10 32 S2 4 10 13 34 41 12 10 a 16 a 10 10 10 14 12 id 10 a 14 8 10 9 is 9 Page 9 of 15 Table 3. Percent cbange from control and average specific growth rat* from toxicity test Nominal Concentration of Test Substance (mg/L) Average specific growth rate 24hr 48hr 72hr 96hr Percent change from control 24hr 4$hr 72hr 96hr 0.0 (control) 0.034 0.034 0.045 0.040 0 0 0 0,( 62.5 0.000 .0..039 0.033 0.031 100 is 27 22 125 0.003 0.039 0.031 0.03S 91 is 31 1.2 250 0.02S 0.037 0.03S 0.032 26 9 22 .2-0-) Soo 0.010 0.026 0.020 0.002 72 24 S6 9s 1,000 0.000 0.008 0.000 0.001, 100 76 100 is. Page 10 of 15. Roma" Nxqft we,&Amoov d HMUFM Table 4. Median effective concentrations (EC509) from toxicity test Zxposure period scso 95 percent confidence limits Calculation method 24 hours 48 hours 72 hours 96 hours (62.5 mg/L 707 mg/L 284 mg/L 255 mg/L --500 - 1,000 mg/L 249 - 325 mg/L 222 - 293 mg/L binomial moving average moving average Page 11 of 15 Ramuom M*ft by--&Am" d MLLPORE OZO. 1984. %idelines for 'TestinZ of Chemicals. Section 2: Effects an Biotic Systems. Retbod 201. Alga. Growth Tn'6i ition Test. Rdopted June Stepban, C.E. 1983. Computer program for calculation of LCSO values. Personal communication. U.S. EPA. 1979. The S&2eoastran capricorautan Print% Algal Assay Bottle Test. EPA-600/9-79-018. July, 1978. Page 12 of 15 Ramiom Malvft br-&"OM d MUFM Appendi)i A. WATN OMLLNT DATI FRON TOXTCTTY TICST Page 13 of 15 . kmwmk idyftW-SA*dbmydMLUPOK Table 3i.l. Temperature measured during toxicity test Day of Zxposure 0 1 2 3 4 Temperature of lacubator,*C 23.0 23.0 23.0 23.0 23.1 Page 14 of 15 Ramume kciyft kc. &bocftv d MWPORE Table A.2. pl measured during tomicitrtest Nominal concentration togIL) 0 (control) 62.5 125 250 500 1,000 Replicate 1 2 3 1 2 3 1 2 3 1 2 3 1 2 3 1 2 3 initial 8.0 8.1 9.2 3.0 8.1 9.1 8.3 8.3 8.3 8.1 8.2 9.2 9.2 8.2 9.0 8.1 8.1 3.1 final 20.3 10.3 10.3 '1.2 7.3 7.2 7.2 7.3 7.3 7.2 Y.i 7.3 7.2 7.2 7.2 7.2 7.2 7.2 Page 15 of 15 RE$OL"NX*VftkV-SA)"M d MUFM EnvironmentLaalb.DataReportForm Parameter- fftTftn ANOW CA Chaft LRI Result J-/kpR7- -TC50 Unit n@xIL Date commmts -7Alpbosq,-:s- Lo@ 87 0-vI@Lu I,/'iI J)B,D-R 'Irs-0 .2&6 It -TCSC> 1-7D IT -IDOC) 15% cm @@,a:__ IDO) EnvironmentLaalb.DataReportFo@rm FOMIOM-13-8-@VM Parameter conww rft1rom PW man (&M Lab0" LR xisgq- -,2xq5% Rosult /COO -Tl,osq is- 9 Unlt Date Commonts q59PC.X (,qoe>-LCID 11 I-C50 77 JL MATERIAL SAFETY DATA SHEET (Intermediate) 3M 3M Center St. Paul, Minnesota 55144-1000 1-800-364-3577 or (651) 737-6501 (24 hours) Copyright, 2000, Minnesota Mining and Manufacturing Company. All rights reserved. Copying and/or downloading of this information for the purpose of properly utilizing 3M products is allowed provided that: 1) the information is copied in full with no changes unless prior agreement is obtained from 3M, and 2) neither the copy nor the original is resold or otherwise distributed with the intention of earning a profit thereon. DIVISION: MATERIAL: SPECIALTY MATERIALS MANUFACTURING DIV. FLUOROCHEMICAL SALT FM-3820 F-8656 FM-4547 FM-4581 F-9459 ID NUMBER: 41-2600-8656-0 41-2600-9459-8 41-2700-4581-2 ISSUED: February 29, 2000 41-2700-3820-5 41-2700-4547-3 SUPERSEDES: February 15, 2000 DOCUMENT: 04-1601-6 ----------------------------------------------------------------------------- 1. INGREDIENT C.A.S. NO. PERCENT ----------------------------------------------------------------------------- DIETHYLENE GLYCOL BUTYL ETHER ........... 112-34-5 35 WATER .................................7.73.2-18-5 35 PERFLUOROALKYL SULFONATE SALTS .......... TradeSecret 24 RESIDUAL ORGANIC FLUOROCHEMICALS ........ Mixture - 40 - 40 - 28 Unknown The components of this product are in compliance with the chemical notification requirements of TSCA. All applicable chemical ingredients in this material are listed on the European Inventory of Existing Chemical Substances (EINECS), or are exempt polymers whose monomers are listed on EINECS. This product contains the following toxic chemical or chemicals subject to the reporting requirements of Section 313 of Title III of the Emergency Planning and Community Right-To-Know Act of 1986 and 40 CFR Part 372: DIETHYLENE GLYCOL BUTYL ETHER ----------------------------------------------------------------------------2. PHYSICAL DATA ----------------------------------------------------------------------------- BOILING POINT: ................>.212 F VAPOR PRESSURE: ...............<. 18 mmHg @68F VAPOR DENSITY: ................N./D EVAPORATION RATE: .............N./D SOLUBILITY IN HATER: ...........apprec. SPECIFIC GRAVITY: .............1..08 Water=l ----------------------------------------------------------------------------- Abbreviations: N/D - Not Determined N/A - Not Applicable CA - Approximately ISDS: FLUOROCHEMICAL SALT FM-3820 F-8656 FM-4547 FM-4581 F-9459 February 29, 2000 3M Internal Use Only PAGE 2 ----------------------------------------------------------------------------- 2. PHYSICAL DATA (continued) ---------------------------------------------------------------------------- PERCENT VOLATILE: ............7.2. % pH: ........................1.0.-..10.5 VISCOSITY: ..................<..1.00 centipoise MELTING POINT: ...............N./A. APPEARANCE AND ODOR: Slightly tinted liquid with butyl carbitol odor. ----------------------------------------------------------------------------- 3. FIRE AND EXPLOSION HAZARD DATA ----------------------------------------------------------------------------- FLASH POINT: ................>..2.12 F CC estimated FLAMMABLE LIMITS - LEL: ........N/D FLAMMABLE LIMITS - UEL: ........N/D AUTOIGNITION TEMPERATURE: ......N/D EXTINGUISHING MEDIA: Water spray, Carbon dioxide, Dry chemical, Foam SPECIAL FIRE FIGHTING PROCEDURES: Wear full protective clothing, including helmet, self-contained, positive pressure or pressure demand breathing apparatus, bunker coat and pants, bands around-arms, waist and legs, face mask, and protective covering for exposed areas of the head. UNUSUAL FIRE AND EXPLOSION HAZARDS: See Hazardous Decomposition section for products of combustion. --------------------------------------------------------------------------4. REACTIVITY DATA ----------------------------------------------------------------------------- STABILITY: Stable INCOMPATIBILITY None known. - MATERIALS/CONDITIONS TO AVOID: @AZARDOUS POLYMERIZATION: Hazardous polymerization will not occur. IAZARDOUS DECOMPOSITION PRODUCTS: Carbon Monoxide and Carbon Dioxide, Oxides of Sulfur, Hydrogen Fluoride, Toxic Vapors, Gases or Particulates. ----------------------------------------------------------------------------Nbbreviations: N/D - Not Determined N/A - Not Applicable CA - Approximately M6DS: FLUOROCHEMICAL SALT FM-3820 F-8656 FM-4547 rM-4581 F-9459 February 29, 2000 3M Internal Use Only PAGE 3 ----------------------------------------------------------------------------- 5. ENVIRONMENTAL INFORMATION ----------------------------------------------------------------------------- SPILL RESPONSE: Observe precautions from other sections. Ventilate area. Contain spill. Cover with absorbent material. Collect spilled material. Clean up residue with water. Place in a closed container. RECOMMENDED DISPOSAL: Incinerate in an industrial,or commercial facility. Combustion products will include HF. ENVIRONMENTAL DATA: BIODEGRADATION: Chemical Oxygen Demand (COD): 1.00 g/g 5-Day Biochemical Oxygen Demand (BOD5): 0.170 g/g 10-Day Biochemical Oxygen Demand (BOD10): 0.355 g/g 20-Day Biochemical Oxygen Demand (BOD20): 0.531 g/g 28-Day Biochemical Oxygen Demand (BOD28): 0.428 g/g AQUATIC TOXICITY: Fathead minnow (Pimephales promelas) 96-hr LC50: 9.3 mg/L Water flea (Daphnia magna) 48-hr EC50: 115 mg/L Algae (Selenastrum capricornutum) 72-hr IC50: 380 mg/L Microtox (Photobacterium phosphoreum) 30-min EC50: > 1000 Activated Sludge Respiration Inhibition 3-hr EC50: > 1000 mg/L mg/L REGULATORY INFORMATION: Volatile Organic Compounds: N/D. VOC Less H20 & Exempt Solvents: N/D. Since regulations vary, consult applicable regulations or authorities before disposal. In the event of an uncontrolled release of this material, the-user should determine if the release qualifies as a reportable quantity. U.S. EPA Hazardous Waste Number = None (Not U.S. EPA Hazardous). The components of this product are in compliance with the chemical registration requirements of: TSCA, EINECS, CDSL, AICS, MITI. OTHER ENVIRONMENTAL INFORMATION: This product contains one or more organic fluorochemicals that have the potential to resist degradation and persist in the environment. EPCRA HAZARD CLASS: FIRE HAZARD: No PRESSURE: No REACTIVITY: No ACUTE: Yes CHRONIC: No ----------------------------------------------------------------------------kbbreviations: N/D - Not Determined N/A - Not Applicable CA - Approximately MSDS: FLUOROCHEMICAL SALT FM-3820 F-8656 FM-4547 FM-4581 F-9459 February 29, 2000 *** 3M Internal Use Only *** PAGE 4 ----------------------------------------------------------------------------- 6. SUGGESTED FIRST AID ----------------------------------------------------------------------------- EYE CONTACT: Immediately flush eyes with large amounts of water for at least 15 minutes. Get iinmediatemedical attention. SKIN CONTACT: Flush skin with large amounts of water. If irritation persists, get medical attention. INHALATION: Remove person to fresh air. If not breathing, give artificial respiration. If breathing is difficult, get immediate medical attention. IF SWALLOWED: If swallowed, call a physician immediately. Only induce vomiting at the instruction of a physician. Never give anything by mouth to an unconscious person. ----------------------------------------------------------------------------7. PRECAUTIONARY INFORMATION ----------------------------------------------------------------------------- EYE PROTECTION: Avoid eye contact with vapor, spray, or mist. Wear vented goggles. SKIN PROTECTION: Avoid skin contact. Wear appropriate gloves when handling this material. A pair of gloves made from the following material(s) are recommended: butyl rubber, neoprene. Use one or more of the following personal protection items as necessary to prevent skin contact: apron, coveralls. Protective garments (other than gloves) should be made of either of the following materials: polyethylene/polyvinylidene chloride (Saranex). RECOMMENDED VENTILATION: If exhaust ventilation is not adequate, use appropriate respiratory protection. Provide ventilation adequate to control vapor concentrations below recommended exposure limits and/or control spray or mist. RESPIRATORY PROTECTION: Avoid breathing of airborne material. Select one of the following NIOSH approved respirators based on airborne concentration of contaminants and in accordance with OSHA regulations: Half-mask organic vapor respirator with dust/mist prefilter, full-face organic vapor respirator with dust/mist prefilter. ----------------------------------------------------------------------------- MSDS: FLUOROCHEMICAL SALT FM-3820 F-8656 FM-4547 FM-4581 F-9459 Fqbruary 29, 2000 *** 3M Internal Use Only *** PAGE 5 ----------------------------------------------------------------------------- 7. PRECAUTIONARY INFORMATION (continued) ----------------------------------------------------------------------------- PREVENTION OF ACCIDENTAL INGESTION: Do not eat, drink or smoke when using this product. Wash exposed areas thoroughly with soap and water. Wash hands after handling and before eating. RECOMMENDED STORAGE: Store away from areas where product may come into contact with food or pharmaceuticals. Store at temperatures below 120 degrees F (49 degrees C). Store at temperatures above 32 degrees F (0 degrees C). Keep container closed when not in use. Keep container in wellventilated area. FIRE AND EXPLOSION AVOIDANCE: Keep container tightly closed. Keep away from heat, sparks, open flame, and other sources of ignition. Combustible liquid and vapor. OTHER PRECAUTIONARY INFORMATION: No smoking: Smoking while using this product can result in contamination of the tobacco and/or smoke and lead to the formation of the hazardous decomposition products mentioned in the Reactivity Data section of this MSDS. HMIS HAZARD RATINGS: HEALTH: 2 FLAMMABILITY: 0 REACTIVITY: 0 PERSONAL PROTECTION: X (See precautions, section 7.) EXPOSURE LIMITS INGREDIENT VALUE UNIT TYPE AUTH SKIN* ----------------------------------------------------------------------------- DIETHYLENE GLYCOL BUTYL ETHER ........ 35 WATER .............................N.ON.E. PERFLUOROALKYL SULFONATE SALTS ....... 0.1 RESIDUAL ORGANIC FLUOROCHEMICALS ..... 0.1 PPM NONE MG/M3 MG/M3 TWA CMRG NONE NONE TWA 3M y TWA 3M y * SKIN NOTATION: Listed substances indicated with 'Y' under SKIN refer to the potential contribution to the overall exposure by the cutaneous route including mucous membrane and eye, either by airborne or, more particularly, by direct contact with the substance. Vehicles can alter skin absorption. SOURCE OF EXPOSURE LIMIT DATA: - 3M: 3M Recommended Exposure Guidelines - CMRG: Chemical Manufacturer Recommended Exposure Guidelines - NONE: None Established ----------------------------------------------------------------------------- MSDS: FLUOROCHEMICAL SALT FM-3820 F-8656 FM-4547 FM-4581 F-9459 February 29, 2000 *** 3M Internal Use Only *** PAGE 6 ----------------------------------------------------------------------------8. HEALTH HAZARD DATA ----------------------------------------------------------------------------- EYE CONTACT: Severe Eye Irritation: signs/symptoms can include redness, swelling, pain, tearing, cloudy appearance of the cornea, impaired vision and possible permanently impaired vision. SKIN CONTACT: Mild Skin Irritation: signs/symptoms can include redness, swelling, and itching. May be absorbed through the skin and produce effects similiar to those caused by inhalation and/or ingestion. INHALATION: Central Nervous System Depression: signs/symptoms can include headache, dizziness, drowsiness, incoordination, slowed reaction time, slurred speech, giddiness and unconsciousness. Single overexposure, above recommended guidelines, may cause: Irritation (upper respiratory): signs/symptoms can include soreness of the nose and throat, coughing and sneezing. IF SWALLOWED: Animal studies conducted on organic fluorochemicals which are present in this product indicate effects including liver disturbances, weight loss, loss of appetite, lethargy, and neurological, pancreatic, adrenal and hematologic effects. There are no known human health effects from anticipated exposure to these organic fluorochemicals when used as intended and instructed. Ingestion may cause: Aspiration Pneumonitis: signs/symptoms can include coughing, difficulty breathing, wheezing, coughing up blood and pneumonia, which can be fatal. WHILE THE FOLLOWING EFFECTS ARE ASSOCIATED WITH ONE OR MORE OF THE INDIVIDUAL INGREDIENTS IN THIS PRODUCT AND ARE REQUIRED TO BE INCLUDED ON THE MSDS BY THE U.S. OSHA HAZARD COMMUNICATION STANDARD, THEY ARE NOT EXPECTED EFFECTS DURING FORESEEABLE USE OF THIS PRODUCT. Ingestion may cause: Irritation of Gastrointestinal Tissues: signs/symptoms can include pain, vomiting, abdominal tenderness, nausea, blood in vomitus, and blood in feces. Central Nervous System Depression: signs/symptoms can include headache, dizziness, drowsiness, muscular weakness, incoordination, slowed reaction time, fatigue, blurred vision, ---------------------------------------------------------------------------- MSDS: FLUOROCHEMICAL SALT FM-3820 F-8656 FM-4547 FM-4581 F-9459 February 29, 2000 *** 3M Internal Use Only *** PAGE 7 ----------------------------------------------------------------------------- . S. HEALTH HAZARD DATA (continued) ----------------------------------------------------------------------------- slurred speech, giddiness, tremors and convulsions. OTHER HEALTH HAZARD INFORMATION: This product contains one or more organic fluorochemicals that have the potential to be absorbed and remain in the body for long periods of time, either as the parent molecule or as metabolites, and may accumulate with repeated exposures. There are no known human health effects from anticipated exposure to these organic fluorochemicals when used as intended and instructed. The presence of organic fluorochemicals in the blood of the general population and subpopulations, such as workers, has been published dating back to the 1970's. 3M's epidemiological study of its own workers indicates no adverse effects. ----------------------------------------------------------------------------SECTION CHANGE DATES ----------------------------------------------------------------------------- PHYSICAL DATA SECTION CHANGED SINCE February 15, 2000 ISSUE ----------------------------------------------------------------------------Abbreviations: N/D - Not Determined N/A - Not Applicable CA - Approximately ----------------------------------------------------------------------------- The information in this Material Safety Data Sheet (MSDS) is believed to be correct as of the date issued. 3M MAKES NO WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR COURSE OF PERFORMANCE OR USAGE OF TRADE. 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