Document mbvGqKO12R7zrQ45095Z1JE40
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<<; JC al V.B BRADLEY
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J.C. LEITINGER/M. S. EATON - WW
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WILMINGTOvN.oDnELAWARE 19898
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: PLASTIhCPRODUCTS AND>RESINSDEPARnTeMENT.
"BB3.. BWC... AKARMCRMKRIHUTSAIG-CEK - CRD, HASKELL
PERSONAL & CONFIDENTIAL
July 18, 1979
R
ECEIVEp,
TO: J. W. RAINES
Wi[g4
FROM: L. F. PERCIVAL sf
Suge ca7t9
ORGANIC FLUORREIVNEIELWEVOEFLMSPIRNETULNTIEMBSILNOAORDY-DWAATSAHINGTON WORKS Ref: (1) L"eDatttaeroJn. C-F.8 EDxopuogshutrye"t,o L7./17F./79P.ercival,
(2) L5e/t20t/e7r8.Dr. Y. L. Power, M.D. to W. A. Bower,
and B. C.R.McKE.usiJcackksoonn,7/J1.8 Wt.o Rraeivnieesw atnhed IdamteatiwnitRhefeDrr.encB.esW.1 aKnadrrh2.
CaonmdpaensyultMaseentfirUngo(ved mFwbAiltoChodT34tUeCsEotmsprarn)yuonna- t7A/2Cm0heaemttboeirnrsgevWiioserwkpsla.annynenIdet*wwwaMisthdaag3tMraeed
THheiasctualstiB.sckCo,wfiMlaclKpurrseeilpciokmritwnoaturolydPPsAtruRedpyoa;rntypWrfaoiscnhedisinsnggstdoantfarWoowmrikltslh'enbomteleotobidengdgiavtteahna.ats
are significant regarding plans outlined below.
tional boFa ousrthe er s BlooSdp hoSualmi pdline gbe takenatsWWat- WItW wtaosmaeegtreetdhethfaotllaodwdiin-g
objectives:
o ECiEhneecrtkhneoarlslemtiihnwedorirevksisd1u5(a)tlosetnacdlurT8r)H,eEntpFlEoyPlykeexpotplioylskeeedtotptleoeraCt-8or
(total 13).
o VACeb8roiufteybxptohssauatrmepfllreuasotrhsiehnroeultihdnabneblfortooadnkelonetvfheerlrosmfil"suToerfdoluceohne"taoteals.
g
MToenfolmoenr" opareeraa)towrsith(onro otphoetrentpiearlsonfnoerl C-f8roemxptohesure for at least 10 years.
83 3
"tteeting vas arranged May 1979.
EID107194
THERE'S A WORLD OF THINGS WE ARE DOING SOMETHING ABOUT 000157
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:
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J. W. RAINES
-2-
July 18, 1979
e Dfelfuionreinetheinbbilooloodg.icaWlWdeschaoyu,ldordebvueillodpupa, prroatgersamofto
define decay rates or buildup of fluorine in blood
by a careful review of work histories and blood
+
dseasmcprliibnegdobfelcoewr.taiWneinsdhiovuildduaaltstemspetlecttoeddetferromminleist
if fluorine in blood levels increases with increasing
yelxheponogsthuahrvsee.'"(LyeeWfaetrs)fsohboosuflwdeixtpaohlssuCor-esaemixnppleotshuaeroebfesfw,oriwniddiitvfhifdeCur-ae8lnst
plreonggtrhasm woiflltimreequGieraersc)a.refuDlevpellaonpnmienngt aofndswuechwoauld
like to review it as soon as practical.
CD&P has agreed to continue to analyze samples for PP&R.
pared ofToa,llbjeolbpsme(eitnctlhuedinagbomveechoabnjieccst)iveasn,d pleirstssonnsehloulads.sbiegnperdethese jobs who would have been routinely potentially exposed to
C-8 for a significant period for the past 10 years.
status CommunicaCtOiMoUnIIwCiAtLhEdWasthoinafgfteocnteeWdorrkesni 'plol yeele soySe, Eesan- Paprpersoe-nt
priate time. Public Affairs (C. Perry) is working with information in Reference 1 and 2 to assist in statements to employees. The
statements should be cleared with J. W. Raines before being used.
Medical Follow-up - Dr. B. Karrh will review data summa-
rmiezdeidcalinanaRelfyesreesnceas needTeedc.tly with Dr. Power and request additional
Dordrecht and Spruance
defer samp ng Dordzeckt une
(TtehxetrilseamFpi.bers)
- sWbeeeangreceodmplteoted
at WW. McKusick is advising Textile Fibers Department of our
present status. Some sampling of affected Spruance employees is
indicated.
untilplais"tTetfloun"dCuaisrteeommesrosre-cAonmpylectoem.munication will be deferred
Notification of EPA (Section 8(e) - Toxic Substances
wCeoenktrotlo
also be
Adcetc)ide- Tihfea r"eSupbosrttanutnidaelrRi8s(ek)"
discussed with 3M.
Cisommrietqutiereedw.illwTohriesviweiwlnlext
LFP:1db
2g
EID107195
FE]
000158
od
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Coptes to:
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3h SS .1N0. D RBe aoiysde,s;JrF.r,PeRC,Dp&PDe,oansB0-tt1)6234
----
a E. I. bWuILPMoINNGTTDOpENh,NiEDEEMLOAUWRASRE&1C9o69m8panayrr
F. J.
C.+F.B. E.
Retmharat/o. 1. Kewmady,a ChiD, Haskell Marascia/R. D. Richardson/R. E. Read, CDG
Simmons/M. S. Sadler, CRSD, D-6032
ToxiGowSE"ANG INGUETRIAL MEINE
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~~
Ewti A a
CONFIDENTIAL
:
MEO TO: FC.hezE,. 3FR2EN6CH), JR.
AA Sle
.
Hy,2% 0
OM: 3. C. WC RUSIGK PpaHot?
"@
Discussion or FuvomocmacALs ITE 34
GReetb2e.tOtnRnesaJdu,l1y.a0n2:0d,KBe5D.og:hN,.RiBReacyhdAa,rdaGF.saokLe.orf,KePaunndeodsyFt,. sb7o.atJh.ieolMaurotafesacBgthe.a,v3e.hC.F.Keorkusdck,
Te
ee xpReirciheanrcdesonatde e3s,cricboendcesnetarsautireoensstascasreoSfooreomregtlasnterAflvuei otrtoocnhceinvtecalsstudfyo
blood of
SPer4aigEiaeln hTaescorbdesenfoSuinsdconnoctamduevder bealeh effects. The Bised satveis
cheateKaetnorn.e"dy Tdreesycriabteed cHoansstkeetleln'ts, vith I seine faces subacute toxicity studies of CD&P fluoro~ Prokop of 3 described a gas chromatographic sechod co deteraie per-
fluoroBctanoic acid (FC-143) in blood, urine, liver, and other biological materials. It can measure as little as 1.5 ppb. A paper has been pre-
pared (copy attached) that should appear in about six months.
aFlcohoedsUhhLeeedav,letlhscheoeff3foHresgceadntohefaalvleuordbiierseeenctFiooaura,edm.pslsaomiydmeogscsheatheapvnleoeracedhsvaenrg1seaedTOLL-ii1vs4el3reaopfseferesacpttiiscoenosr:
Ties to lessen enponure. Blood levels of sepleress moved to ocerions
eoiutrsuirdaebiteh:echfoluuaorreochofemiocragalniacreaFlhuarvienedrtovppeexdcroenrluyd,sligFhattley,vasaltLhiotuegmh
.
tFroart'eTdS Tbyradsataaadonheadn echmeploMiygeneonwehoblhoaoddbeLeenvelinofthseayflu(oFraoblceheImi.cal area
EIDIOTIT
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(*Transparencies attached to copies of French, Simons, & Reinhardt.)
&
I 000159
:
MEMO TO: F. E. FRENGE, JR.
-2-
July 23, 1979
TABLE T
ORGANOFLUORINE IN ONE EMPLOYEE
Date
Blood CercIentration,Epspm
Urine Conc.,3yg/2 br.
Jocutly 7767: 309 0.0035
aMapyr 7788 6n
53
(at this potat, he vas transferred to smother area)
JJuunee 163,,7788 7616
82762
Jauugly 7788 6565
117650
Joacnc 7798 i5s9
126200
aor 79 a
Canton3. gTothebloogoradniscampflleusorifnreomva8spesaisgainntfsicianntlayChlionweerse(v0i.l0l0a4g-e0.3007mipplme)s, frtohamn vofalutehse fgeonuenrdalinU.dSe.veplooppueldatciocunn)t.ries (e.g., 34 found 0.002-0.13 in 106 members studyUboefl40sa0i0d-50t0h0atemaplUonyieveesrswihtoy ohafveMinwnorekseodtaatprothfeesoslodresits danodinbgigagnesetpi3deMmpiloalnotgy mhaasnufaacltouogrivnagyfltuoorgoo.chemicals. Nothing noteworthy has shown up, but the study resultAsyeofartahegoblaololdemstpuldoyy.ees3Hinrefcleunotrloychetaoildcalthmeaanuafbaouctturite vaegraien.tolAdbotuhte 60 eALmLplwohyoeeshavien bteheenfflouuonrdochtoemhiacvael ealreevaatheadveorhgaadnibcloofdluoorrginaenibclofolduorlienveelmseahsauvreed. bteheatn 1i0nfoardmveerdseofhethaelthfacetffaencdtsthoaldvetbhaeten3Mredloaetsednotto kitn.ow vThhaetemitplmoeyaeness,habvuet taken the information calaly. FC-143Griifnfirtaht,s a3ndmmaonoakgeeyrsof(steeoxiacttoalcohgmye,ntr)e.porTtheed defafteactosn v9e0r-edaysismtiuldairestoowfhat Du Pont saw with similar materials. Thus, the liver vas the main target organ. rats,Thbeutremavlasesnoretsaiginniefdicaabnotutdi1f00ferteinmcees mionreefFfCe-c1t4s3!betwGereinffimtahlesaanidd hfeemwaolueld send me details on this.
EIDI07174
E
000160
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MEO TO: F. E. FRENCH, JR.
a
uty 23, 1979
` soon. 0 This matyarsthow svahcearebolFdCo-1n43stuidsybeofingcussttoolraebdeliandthiCFBdCy.HO 50 race the skSitnutteaessiloyf.FC-143 dust on animal skin {ndfcates it does mot penetrate one co3mpatnnydichaastedintienrteesrtesitnginresmuoltthse.r review in about a year, or vheasver .
. poem
8
EIDI07175
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000161