Document m8yyZaj5x34p4YjQXwQOkXD0

Co. . | 1p Keira Spmaeann Th8506,~. Salt Vice President and Safely Services: B7u0iBdonxg3472315.36 EGER 17 Certified Mail FEHR - 0S03_00573 1324 3m May 20, 2003 GEG - 29-372 - DEoPcAumEeasntt--PrRoocoesmsi6n4g2C8eAnttten:r Section 8() OfficeofPollution Prevention and Toxics U1S200EPPeAnnsylvania Avenue NW. `Washington DC 20460-0001 . ;3 Cid NO CBi beor RE: TSCA 8(E) SUBSTANTIAL RISK NOTICE ON: Phosphonium, rbuitpahneensyull(fpohneanmyildmeet(h1y:l1))-(CsaAtSw3it3h2315,1029,32,.3),3,4,4,4-nonafluoro-N-methyl-1- Dear Sir: 3M has received data for an acute eye iriation study in rabbits conducted with `mpehtohsyplh.on1i-ubmu,tarniepshuelnfoynla(mpihdeeny(1l:m1e)th(yC)A-S, 3sa3l2t3w5i0t-h931-,31),2(,T2,P3B,P34C.44,4a-mniodnea)fliunodrioc-aNt-ing ocular corrosionofthe eyelids and nictating membrane. The study was conducted by NOTOX Safety and Environmental Research. Single ~~ samples of approximately 51 mg (a volume of approximately 0.1 mi) TPBP C4 amide & oo, w48e,reanidnst7i2llheoduirnstoafotnreienysteilclaactihono.f three rabbit. Observations were made at 1,24, I97g3 3% Ninectrwoosiasnoifmtalhseonnicdtaatyisng2,m3e,mabnrda4n.e Iwnaasddoibtsieornv,endecirnoosniseoafnitmhaeleyoenliddasyswasasneden4iannd 5 35 + onincetaatniinmgamleomnbrdaanyes,3itanwdas4.coBnacsleuddeodntphraetsoecnuclearofcnoercrroossioinsohfatdhoecceuyrerleidd.s andlor 2 Doumreianlg tihnejuorbysewravsatsieoennpaesrioopda,ciottyhe(rmoacxuliamruemffgerctasdewe2r)eanadlseopniottheedl.ialSdpaecmiafigceally, (immiataxtiimonuomft6h5e%ocofnjtuhnecctoirvnaeeawlaasrcsae);enriadsiarledinrersista,ticohnem(ogsraidse, 1a)ndwadsisocbhsaregrev.ed; and A copyofthe final report is enclosed. PplreoavsiedecoandtdaicttioAnanldrinefworSmeaatcioant.(651-575-3161) ifyou have any questions orifwe can 3 EPiA in ~ (R000R831S8567 owor I Document Processing Center Page No.2 May 20,2003 nOunmcbeeardpoocsktealt cnaurmdbteorChhaesribeKeendraoswssikgin,ed3fMorCtehnistesrubBmlidttga.l2,2p0l-e2aEs-e0s2e,ndSt.thPeaudlo,ckMeNt 55144, Sincerely, Aa E. Reed Leh StaffVice President Environmental Technology and Safety Services Enclosure