Document km5oqV1z7VjKa9X97drk0vzMJ

Air Sygiens Foundation of Ansrics, Inc. 4400 Fifth Avsnus, Pittsburgh! Pa. June 9, 1939 ON INDUSTRIAL DISEASES F MINES FOR LEAD 1T1CES. circular, bars announced ths approTal\bNtEe U. S. aplrator for protection against T^weAMSDicpersoida, vd mercury, aangnnaae, arsanlc, dropper zinc, ate. of this typa to racaiTa tht approval of ths Bureau. QBL A w publication It %)f to ba issued educational material o: contains itoa on ths reporting of occupational tarest. nt of Health, Columbus. 11 contain informational and _ era The first issue, April 1939, of ths department, mobile laboratory, state and othar It of general in- on Dust raT^adustrlal Unions NOTE ON AN TOR DUST .Dunn. 7. Ind. 3yg. k Toxicol., 21, 202-3 ( A descrip'ttjottfjdflven of a new call tf/atfr?g.ppeee jj^^untlag impingor dust samples, The ara<2fe&conslsts of too parts, onar^whid glass plate 1 at. thick, grojg^v^n^th surfaces, with a central hpl^pf _ disaster that the cell approximately 0.2S ml. The ot ls^^rger plate of optically liahad glass. Both are of "pyTex" _ Aay^ratable cower glass, such those now used, may be enployed as a covert Ti^hew cell greatly ra duces ths loss of time In cleaning and raccnau the wrotord Sedgwick-Rafter call. Ths comparatively large sealing area prevent* leakage of air into the cell caused by evaporation of ths. liquids Althoi^h no da&mite data has been collect ed to compare counts using the new'.cell with that ofjbS Sedgwick-Rafter, rou tine plant studies have Confirmed its apparent ecouraey*^The cell could also be easily adapted to plankton, sewage or bacteriological SQjnes beesusa of the simplicity of <****{" and reel stance to attack upon autoclai\starlllzatlon. 439 TBE RATS OF PRODUCTION AND TBS TREE SILICA OQOTBir OF IBB HKf^DUST PRODUCED BY ,R0(Z DRTTJ.TTIg. A. Shaw and 7.Q. Crahsm. Trans. Instn. Min. London, _9_7 104-13, (April 1939). (British). Ths free silica content of fine dust is almost always Isas than that.of the rock from which it is formed, it is dependant also on the rata of drilling, being m slightly higher ths slower ths rats of drilling. Ths free silica dust produc tion expressed as grams of dust per foot of hols drilled say bs takas as an in dication of ths silicosis producing charactsr of ths rock. Ths results indicate that all rocks from which more than 29 of free silica-dust are formed per foot of hole drilled should bs coaaldarwd harmful, ad that prseautlons should than be taka. PLAINTIFF'S i EXHIBIT PLAINTIFF'S EXHIBIT iy/V-oca-icH .cd Hsfarencsa to Hacsot Literature - 2 440 SILICOSIS AND ITS PREVENTION. J. S. Haldane, ?. Haynes, A. Shaw and J. Q. Graham. Trans. Inatn. Min. Engrs. London. 97, 40-67, (April 1939). (British). It is suggested that the toxm silicosis be applied only to a fibrotic condition of the lungs in persons with an exposure to dust containing a high proportion (500 or more) of free silica. Clinical and radiological examination should not be regarded as sufficient basis for a diagnosis unless there is a reasonable history of exposure to free silica dust. Although a large number of coal workers in South Vales hare been certified asnjfiicotlc, the work-hi stories of the cases show that the sen hare not been suhlActad to highly siliceous dusts. The phthl sisdjafch-rate among the coal nirdM^ar shown by their statistics, is not s^, niftdjagtly hlghosNthan in tho^ene^z population of the district. The dde: should not be attributed to as has It is emphasized, however-Jjl(it}tljie^in- halation t will cause pulmonary dnsian^Pollow- lng the ing discussions by otJwfifcnujnBritiea in the field. the authors' definlfftjnA^r silicosis (shore) silicQgls'raSouth Africa hate been ul, the paper con- trib disease. &_ 441 07 THE MEDIC 1937-8. H. M. Stationery Office, London, (1939) Aaong the large nimbe in this report are some dealing directly with induatr coal ainara, which resembles silicosis clinically, not compensable, whereas slll- cosls is compensable, continue the study of anthraco- sis in South Wales, on is the work of the Com- aittee on Toxic Solve ._ Assooietion of Cbeaj, cal Manufactur- ers, checks at oxL^u^A)stage ther to^city^of^ay new solvents that are intro- duced. Mention i3m)mp5e of a publication whit^jM zae the Utarature on toxic solTeBW^tfpJniling a very us Other less important research- es along-qttw&Flal health lines are 07 "CORIOCS Bonus* IN THE It CAN COLO MINERS. Llama. J. Path. & Bacterlol., 48, 41 ). (British), Lous bodies" Is the tea often applied ti structures found in ^bestotlc lungs. They are light colored, ones hare been found in the lunge of coal miners. The author reppapts bi on such bodies seen in the lungs of 3 South African gold minershas examined. Both light and dark colored bodies were found, and in some lungs^Both types were present simultaneously. There was no constant relation, however^, between the presence of bodlee and silicotic findings, and Dr. William is i^p^that tha bodies are not significant in the development of anthraoo-sillcosla 10^he coal miners and trimmers she has examined. They are probably tha result o^^aaee inhalation of fibers or spicules. These black cored bodies evidently cahngm be produced ex perimentally, although the pale asbeatotlo ones can be. 443 THE FROroCTiaN OP DOST IN HAND HEADDOS AND MEANS TOR ITS SUPPRESSION. J. 4. Graham, D. G. Skinner and W. H. Walton. Trans. Inatn. Min. Sngre. London. 97, 83-103 (April 1939). (British). Experiments are described which illustrate tha concentrations of dust in the chief operations involved In the driving of hard headings, namely drilling, shot firing and filling. The moat important found to reduce the dust was ths use of eat drilling methods. The use of a mist projectsr, with a wetting agent la the spray eater, was only slightly successful. References to Recent Literature - 3 A DEVICE FOR ARRESTING EXPLOSIONS. 0. Allsop, F. X. Hartwell and R. 7. Wheeler. Trans. Instn. Min. Engr. London. 97, 20.39 (April 1939). (British). A description In given of arrangements whoreby firedamp explosions in coal mines can be extinguished. The arrangements involve the provision of (1) mortars from which a cloud of incombustible dust can be projected Into the path of the explo sion* and (2) thermal relays which* when subjected to the heat of an explosion, close an electric current which operate# the mortars. The incombustible dust found most effective consists of Mi^anon salt, 180 chalk and 2% magnesium carbonate. Tests made with the have proved Its effectiveness. 445 Only. Min. Cong. X., 25, blam of Industrial health is not always factor in his costs. Tho metal ml itry is many other industries* In ths one im- namely silicosis. The autho: [or of Mines, traces the dust ccntrd&Sneasures of that company The paper broad discussion of control. 446 TEE DOST FRO: 18-19* 72-4, (May 1939). Duet control is an lmpo: trial engineering management and should be given considers! ence has been g"*"*<* during the pest and industries have found control of the dust problem has not been prohibitive. G .van to dust* whether hygienical!? significant or not, dings or new processes that may be potentially dusty uld be made at regular intervals to check the of the systems-,, to g^sin higher employee morale and to find hazards. -47 447 AFFL' CLEAHDO METHODS. Fred ted description Is given of tl 67, 44-6, 92 (May 1939). the new cleaning depart- ^pf'a foundry. Small castings are di l^eblast machine; largo tings are cleaned by first removing the .of high pressure water, then blasting with steel shot. All duet^arrestiag^js by wet methods and the sludge Is reclaimed. This modern installatlom^as noronly almost elimin- atad the duet hazard la the foundry, but has realigns saving of ovar 75* in the time of i ammrlng cores in large castings. ^ ________________________ ______ ___________ 448 PRACTICAL ******* JQR TBS CONTROL OF HTOnXEC OFOSORE&^A. A. Coburn. Am. J. Pub. Health. 29, 501-6 (May 1939). The author presents a mama 17 of the general aoaslderatloa^d^ prevention of industrial diseases. The hazards of duet* chromlisi* lead, v/fiL other materials are discussed. The paper was presented at the October 28* 1938, nesting of the American Public Health Association in City. Following the paper Ls an 8-page discussion compiled by C. L. Pool which summarizes and describee typical methods for control of exposures in certain industries. 449 BEYOND XTHT * TEE LOTS 07 TEE LAV." H.E.2oberts. Ocet. Hazards & Safety, 1, 13-18, 28, (May 1939). The trend of court deoisloms is definitely towards application of ths conanon law, of consldarlng an occupational dlsaoso the same as an Injury, wherever spe cific coverege has yet to be enacted. Cases are presented to show the devious reasoning by which ths courts have made awards for Industrial disabilities and to show management why it nay ba wise to look beyond the latter of the law in determining ita responsibility. References to Recent Literature - 4 490 ALLAZHC DUST IN BITUMINOUS-COAL MINES WITH WATER. O. Harrington, J. J. Forbes, F. I. Cash, B. H. Denny, C. A. Herbert, D. J. Parker, C. W. Owings and a. V. Hiller. U. 3* Bor. of Hines, Tech. Paper, No. 593 , 59 pp. (1939). For sale by Supt. of Docmonts, Washington, D. C. for 15 cents. This bulletin describes acre fully (see Abstract 118, 1939) the researches of the Bureau of Hines on the use of water In reducing dust in coal Bines. To pre vent dust explosions in mines both water and dusting methods are being used in conjunction. The dusting cannot be applied within 15 feet of the face, and it is at this point where such of the coaledusts and gases ore encountered. This bulletin esnaorates the dust producii^^ources and describes practical mot hods of Ujrfhg eatsr as one of the aost^tpsaot^ve methods of allaying dust in bitu ous\<gu mines. ^Excellent 1 lliitryxons and sketches are included. Apt the ri&B^ion ef^ust becajaMTox its explosive qualities an increase the efffcqidfcpy tmMnr&rs claimed in sama mines, due both to r d^ttis- caafort fcrom coal dudCwn&to Increased visibility. 451 DIAGNOSTIC tive Editis the Asaocl This bj___ _ !ustrial phys opportunity to detect at a proper diagnosis, health hut also that of 5SIS OF THE LENDS AND DES. Tenta- sulosls Association, 1938. toinable from W. 50th St., Nee Yo is 10th edition presents simply and pulmonary tuberculosis, workmen has an unusual et should help him in arriving e* not only improves industrial 452 TUBERCULOSIS MORTALITY IN OKS OF MASSACHUSETTS AND ICCHIOAN. C. C. Dauer. Am. Rev. 18^ (May 1939). Tuberculosis aortal! bhen ht^C^y in four Massachusetts cities than in a similar gro o ssme^Sizo la Michigan. It appears that the difference taLM^tSlity in the tab- cities can best bo explained on the basls^hqprs unfavorable enrtrotment Hassachua^ya^roups. It also appears'that 1 social conditions In the ily the composition of the popuJ^l^vlth respect to nationality mtaT' part in these differences The paper includes tables 's^jitatimi^ which describe the data to age groups, type of occupational ipulatlon and housing ities. REPORT OF THE DEPARTMENTAL COldCTTEE CN COHFBGATI^ F0Rv ROOM WORKERS. 3. M. Stationary Office, London, 1939. The Ccnlttee was appointed to consider an equltdble^impensatlon code for card room workers in eotton mills. For a long time It warn thought that there was ac specific dlaeaae among tbe operatives which could be tthhCejnfSbJject of precise clinical diaonaia, hut the present Committee reccmmendsiSh peadsalon of mrkera to apply for compensation for a respiratory dlseasm^taaed "byssiaosia," after haring worked in a card room or cotton blowing room for20 years or more. It It now thought that a special medical board la able to arrive at a definite conclusion as to the occupational origin of this disease, which reeaahles bronchitis and emphysema and which is presumably characteristic of the occupa tion* 434 THE FLOW 01 AIB AND ITS DIRISIBOT'ION THROUGH DUCTS. PAST 4. DUCT LAIUOT. J. R. Zwickl. Heat. 4 Vent., 36, 48-50, (May 1939). See Abstract STB, 1939. This paper discusses the methods of duct layout and design based on technically correct methods. All seetlons of the system are first calculated as equivalent round ducts and then their equivalent rectangular dusts substituted, if necess ary, to fit the structural requirmnenta of the building. The designing is based on the flow in the selected main duct and branches are oaleulated as percentages of the mala. Equations for calculatingduct sizes and head losses are included and explained. References to Recent Literature - 5 (C) Psora on Industrial Poisons, Cancer, Dennatltls. etc. 455 RESPIRATOR! HAZARDS OP ELECTRIC ARC WHXIHG. 0. A. Sander. Isd. Med. 8, 177-60 (May 1939). Twenty years of electric welding experience seen to indicate that the operation la not a hazardous occupation provided the time concentration la kept below a certain level. This danger level appears to be higher then the concentrations 456 GASSBB ACCIDENTS. S. E. Wilkea and D. Matheaon. Ch*t. fc lad. 58, 316-23. (April 15, 1939). (British). The authors, as inspectors of the Factory Dopartnant 19 , harve tabulated the reported gassing accidents that have occurred dux!a st six yoars. It is shown that carbon nonoxide produces far nose accidea any other gas. almost as many as all others combined. Other gases esc are hydrogen sulfide, sulfur dlo^de, chlorine, nitrous fiaes, aanla, benzol and trichlcr- ethyleno, to aeatlon a few. Accidonts are classed as those due to "expected" gases and as those duo to "surprise" gases, and soae at the most serious acci dents aro caused by the latter in locations whore the gas is not aanufactured or handled, but is generated or encountered by accident. It is noted that chemical works do not produce a high proportion of the aoeldaats, and that most are in the Iron and steel trades, particularly the blast furnace and its associated equipment. Lenghthy descriptions are given of certain general precautions to be followed. References to Recent Literature - 6 459 WAR OASES AMD INDUSTRIAL HAZARDS IN THEIR MANUFACTURE. H. N. Cole, J. R. Driver, S. S. Bowen and 0. Cooper. Arch. Donut, k Syphilol., 39_, 45-54 (January 1939). The authors were consultants in a factory in which dlphenylchloroarslne (DA), chloroacetophonone (CN), diphenylamlne-chloroarsina (IK), dichlorothylsuiflde (3S mustard gas), and phonyIdlehlororslns (stern!to) were prepared and which act ed as Irritants on the skins of workers who were exposed. The procautions and treaments In the use of each aro listed. In general, the authors suggest the following prophylactic measures: (1) absolute cleanliness in the plant; (2) change of work clothee erery 2 days; (Ik careful washing of hands and face bofora each meal; (4) bathe and change to s%Net clothes ovary night; (5) use gas masks in al^\operatlons where exposure Jta^BangBroua gases is possible; (6) with all prodww except mustard gas, t^e whfinng of rubber gloves and a mustard 3uiti (7) tage^ate treatment of eSjb affected by DA or EM with freah 3olution?^f^V sodium ^pochlordj^L^ An>^ected by CN should be treated with lO^^Siuttmh of sodium hi^fbonateO/^4\^ ^v) 460 THE DETBOTlt AMD VAPORS IN INDUSTRY. S. Bv*4K^fcr. Cham. k Ind., 58, 1939). (British). The sense/ harior of animals ere boejrtunrbHable as general method atmni nco of tracaa of tpmd^gjues encountered in many for simple, saMnLeeU-quantltatlTe tests, re to rery of gasg^nawdpors is pointed out, end the suitability of ICUS84 vcrlptlon le given of such a method for the detectlc of which have boen published by the Dept, of Solestifle search (England). Thoae published to date have referred to hydrogen cyanide, sulfur dioxide, nitrous fines and benzene; all hare px. these abstracts. 461 T3E TOXICITY OF ORGANIC^ McCZufkin. CChhou k Ind. 58 , 339-42, (April 15, 19M).^(HrMi Acute and chronitQmvrolns by vaporapnf o: aaples of pol&nxn^in man are givea^^The not onlrrf ^ra^eure to high concontrat^oha b stoodyWMB of axpoaurea to low concad^gfd,ona solvents are doscrlbed and exhas been to stress the danger the less frequently underlearor realization of these do much towardj the applicatttjs^of in the use of these sub- 'in- Industry. 5LQRIMETRIC DETERMINATION OF HEMOGLOBIN AS " BIN OR AS ACID EB1A- TIN, BASED ON MANY INDUSTRIAL-MEDICAL BOARD mUDOTIi Deutsch. Arch. f. kiln. Mod., 183. 379-86, (Fab: In two-thirds of 400 samples of blood, the hanogl Hueperdinck. 1939). (Gexssn). use by Burker* s hamo- globinometer end the Zelas-Ikon bemometer (add were in agreement. Occasional acid hemmtla values differed greatly from tJfcjSq^by Burker's method, probably beemuae of wide variations in the course of fosimtlon of acid hematin. By Burker's method, absolute hemoglobin content per erythjsh^te showed very little variation In the 400 subjects. Of the total number had 5 to 6.2 million erythrocytes per cu. m. ^ 463 CHRONIC CARBON MONOXIDE POISONING AND PERNICIOUS ANBSXA. H. Bledexmsnn. Folia Haematol., 61, 186-200 (1938). (Italian). A subject repeatedly exposed to carboa monoxide developed hematological and neurological symptoms ladletlagulshable from those in pernicious anala. Tho rapid regression of the neurological signs under therapy lead the author to re gard the algae of pernicious anemia as symptomatic consequences of ths carbon monoxide poisoning, rather than as indicators of an Independent primary perni cious ansmle. It Is suggested that sene apparently refractory cases of perni cious anemia may be due to unsuspected, repeated exposure to carbon monoxlda. Raforencas to Recent Literature - 7 464 METBDD8 FOR TBS DETECTION 0? TOXIC CASES IK INDUSTRY. NO. 5. 1HTROUS TOMES. Dept, of Sol. & lad. Research, Greet Britain. H. M. Stationery Office, London, 1939. Nitrous fimas are usually reddish-brown in color and consist of e mixture of NO2 sod 4. with possibly traces of NO. Dangerous concentrations may be en countered in many Important industries. They are also encountered in connection with electro-plating, engraving, natal cleaning and photogravure processes, and are fomed during 037-acetylene welding when the flame plays on cold steel in a confined space. They have caused fatalities during the heat treatment of metals in molten nitrates. La the teat demnbed, one of a series for use by unskilled personnel, the sample is puaped<tfem%8 a solution of a-naphthnlene and sulj sid in ecftle acid byj steward hand puap. Tha number of strokes, ol >btaij sts jse-plnk color detezmlnes the concentrati itecti at^L part in 100,000 ( 0.03 ag./l). Detail ~ ' preparations of the reagents and ssm] 465 C5EEBRAL 'ATHT IK CARBON MONOXIDE F01 7. E. Hsii and 7. L. Cl 92 (1938). Thstt&taK re; a two cases of "raMTO&2> carbon monoxide poison- Lch lve laalone dawiiojM&'ln tbo deeper cerebral 'substance--1( an AcecrU^^MStT are the basal lesions. Of spiolal interest ia^ bil*tfi\ioKftenlng of the globus pallldus in these cesea since pathognomonic of acuta carbon mon- oxide poisoning. Aft i^ng^ffca^lgj^ta leaiona ccemonly found and reported, the authors discuss the ee which hare bean presented to explain their development. They elusion that no single theory seems to ba adequate to enttfeitj^the action, of this gas cn tissue cells, and that probably ctoreact "together. Anoxemia, specific vascular disturbances, cal;factor- o>eculiar blood supply in specific parts of the lcularly in the braanpj.are bollowed to act together in producing ^logical losions found. PAHOffl ON THE POSSIBLE OF CERTAIN OF THE CHLCR- 3GARBO WITH SOQGESTTQNS FOl iNCBrTRATIONS IN THE AIR C. E. Drinker. J. lad. 21, 155-9 (May 1939). perlaeots on the toAeity of theee compot continued and are report- ed in the paper. It la wall known that a _ ^ __c_h__i_l4a_l_oi\m is effective in preventing acute etrophy of the llrer from exposure to^kbon tetrachloride. Tc discover whether calcium in the diet would protert^sgainst liver demage from a to3dc chlorinated hydrocarbon, two group# of rats^ilaro fad diets of high and lew calcium, reapectlvely, and subjected to inhalation qt high concentrations of a mixture of pasta and hmxmchloncphthalanea. It was fuiiL>that a high calcium diet has no protective affect against the charaeteriatro^kver lesions caused by these compounds. To check e supposition that xanthine i^Mtlone reduced the toxicity of thee* compounda, another aeries of animals waa^istpoeed to the vapors, and part of them were givan nnthins in addition. So differences in the effects were noted. Thnt the chlorinated hydrocarbons are broken up within the body woe proven by a significant lacremaa in the urinary chloride following inhalation of the compounds. Included in the paper is e list cf 15 of the im portant compounds of this aeries showing permissible limits of these substances in air. Most of them contain from 45 to 680 chlorine; the limit of all with but thraa exceptions, is.0.5 mg. per cu. meter of air. The exceptions are: trlchlcr naphthalene plus e trace of tatrachlornaphthaleaa -- 10.0 mg. per cu. a.; chlor inated diphenyl -- 10.0 mg. per cu. m.; and tatrs and paatachlornaphthalenes -- 1.0 mg. par cu. m. References to Bacsnt Litsrmturt - 8 467 TOZIC EFFECTS UPON RABBITS 07 PEMEACHLORFHENOL AMD SODIUM FEMEACELORPHEHOL. R. A. Kehoe, V. DeielmaBm-Gruebler and K. 7. RitmLller. J. lad. Rjrg. it Toxicol., 21, 160-72 (May 1939). Pentachlorphenol is used commercially os a preservative for wood and wood pro. duets. Slnea annual handling of treated lumbar cannot ba completely avoided, experiments on the material wars carried out to check the reported toxic proper ties of the material. The substance whan dissolved is capable of penetrating the skin surfaces and the investigations ^Mre made with this in mind. PentachLorphenofkas wall as its sodium salfr^toa^nbsorbed into the tissues (cutaneousli or wnpllrtaneouflly^ in sufficient q^fislty, produces an acute toxemia. The doae^/fWmlled cutsfifeual^ varied, depending on the solvent, fas3mN o39ilKmg*. nAiM/e*t5tL#logrmik'of (in pine oil) te 390 mg. per kg. (id^LJ^r aotl6meAm^^atally usually recovered fully wlthlg^rnyi short periods dication that the absorption of repeste^aSkll doses induced iaonlng. It. is stated, howevar-rjlmg^ptas latter point needs ion and for this reason the mawtpirshould be em- ployed 468 07 DSH7AZI7SS tug, S. 0. Calvary, H.J. a. TM an ^excellent paper p extensive series of m ate* its 8 Toxi cugh 173.801, (May 1939). the literature and reports on compounds in determining their tonicities. Over 2600 i the tests and the methods of statls. tlcal analyses tnployed Lteresting. After correlating the in. formation in the literature of the experiments, it is concluded that ethylene glycol, di 1760. lsne glycol aono-ethyl-ether, di- ethylene glycol mono, __ ^ui|SL dio: hould be entirely omitted from food and drug preparatl propyl should be avoided except in very small concentre' FATS 07 IN THE 0] H. Johnston. I. Bio 769-70 (March 193` ic acid wes identified in t] which repeatedly inhaled ng doses of triehlorethylans. it as a conjugated pro- r may possibly be a decomposition produe* XX si complex unstable und actually excreted. There are indications thal same material is pre- in the urine of htamns expoaod to trlchlorethylene, 470 TRICHL0RSTHZL2MS DBSOASDO TASKS AMD THSIB 3A7B OPtR^IOH. V. B. Harris, C. 3. Ford, F. A. Patty ead T. Hatch. Xadust. Bull., I. X*^tmte Dept, of Labor, IB, 132-4 (March 1939). This paper gives the results of a survey of 90 plants uiu^Ptrlchlorethylane degreesing teaks, with detailed survey of 19 of these stanad* Racomaendatioaj are made for the design of equipment, location of eqoi^antT^ocal. exhaust ven tilation, and operation* Dimensions of tank and roam, quantity of floe and rate of floe for adequate ventilation ore given* The exhaust ventilation should be applied laterally at the edges of the tank since the heavy vapor tends to roll over the edge and fall to the floor. A ventilating rate of 60 c.f.a* par foot of tank perlmstar has bsea found to b# adequate. This produces an air movement of approximately 20 f.p.m* toward the exhaust openings at a distance of one foot from the slot* It is necessary to kaep the rate of air flow as low as possible to nmintain efficiency of control and to prevent too large losses of ths sol vent. References to Recast Litsrsture - 9 471 TgrRACgaCTIHELaa IN THE TKEATMBfT OP 33QEH0RU DISEASE WITH SPECIAL REFERENCE TO ITS TOXICITY. P. B. Fernando, M. d*Silva, 0. I. B. Stork and 0. R* Slnnataaby. Indian X. Had. Rea., 26, 759-83 (January 1939). (India). Tetrachlorethylene, studied in 111 patlenta, was found to be effeetlre in expell ing hookworms; a single dose of 3 cc. for adults will expel 100# (as many as 510 'Afoms) but baa little effect on round worna. Careful examination of each patient was made in order to check the toxicity. Several liver testa were employed. No appreciable toxic affect on the liver was noted in any of than even in those re ceiving double the naxlnun adult dosM&i general use. No depressant effects of any importance were noted and no teno{Wtion on the kidneys. There was occa- s1otlafygiddlneas,, faintness and wepypesa but these were only temporary. A is of 4-5 cc. can be given to adults children are also discussed. 472 POISONDB IN THE CAT. II. *CE OP L. Stewart and A. Cant Path. 26, first article in this e re No. 756, 1938. cats, divided into The first re- econd group, one or more divided. Two weeks trachlorlde os Croup I. Cats ala and the change# noted, second group in the first 6 days end of 8 days, the Croup II livers of extensive residual damage in ilirublnesrta, retention of brcaxulpha se with ligation of ducts. 473 ON THE 7AS0H0T0R SYST2H 37 ANESTHETIZED Ccmpt. Rand 3oc. blol., 130, ~ih)" TOXICITY OP HJBEfwE^/ R. Arch. Intern de Phams col. 123-53 (February 1939)% 1 describe Dautrebando* s mark bnj4 >coemercial benzene" on the cantral^h^jrou* gyl system and the myocardium, and present^thaLrei cal effect of ":rys*aithe peripheral tbso- f similar resoerch on If) the toxicological affect of chemically purg/benzei ) a comparison of tho effect of comerclally and of chemically pure benzine, (3) the origin of the greater toxicological effect of commercially Experiments conducted on three organs (hsort, intestines, and vasomotor ) showed comerclally pure benzene to have a greater toxicity than chattel e benzene. Research was than conduetsd to datanttna the compounds which ei this result. Fcliaw- log the fractionation of comerclally pure benzene into* rtant groups, it was found that the fraction boiling from 80.4 to 81.2C. test toxicity, greater than pure benzene itself. Further studies of this tlon and of ths impurities in the substance are to be undertaken later. 474 ^^Jj HVDUiiflm IBDDDCED 3? a in A I2AD 1Q2Q. X. W. Sdington. . Hygiene, 38, 683-7 (November 1938). (British). Smarting eyas, markedly congested conjunctivas, end a stinging sensation in the aosa and throat were found in 12 workers in a lead mine. The strong mell of hydrogen sulfide in the port of the mine where they worked was traced to the stagnant mine water in which there were sulfur deposits. 3mples of ths water yielded greet numbers of bacteria. Improved ventilation eliminated the trouble some gss. References to Recent Literature - 10 473 mrOZICATIONS BY BBGENES. M. Duroir tad H. DesoiUe. Presse mod. pp 331-2 (JUrch 1 1939). (French). Acuta lotoxlcations, usually by accidental azposura to large concentrations of vapors, cause the seae injury as do other lipoid solvents. The first symptoms are inebriation and vomiting but those disappear rapidly in fresh air. A acre severe fora causes loss of consciousness or 'aeart failure and death. In chronic poisoning only the aromatic hydrocarbons of the benzene ring cause blood distur bances. Impurities play a iainl1 role and benzine does not seem to attack tho blood. Methods of tresU&ent and prophylaxis are given. If exposure cannot be prevented by enclosure of the processor adequate ventilation, some other sub- stanS* should be ployed. Lasifc^hra&s Trench Society of Hematologists re$ appeasable, benzenes Bust be prohibited 47S FATAL fors. During amounts none shoved strictio: ular ^ _ there Lag, but on * he suffered a again fall. This waj the slightest movement, and the man died 6 hours the cheat). BREATHING HHJRUGiy SULFIDE GASES 83, 1149 (1936). (German) n sulfide gas the patient tor t ugh others in the laboratory me: exposed, The patient had a dizzy spall chest con- had irritation of the tmuti Wbugh, weak and irreg- ffuse bronchitis, vamiting. The next dfor was 126 mg.%. Ho was mg orders and actively moving pains and the blood pressure fever and angina pains were felt at tment the condition become aggravated pectoris (severe constricting pain in 477 EARLY DIAGNOSIS OF Wchnschr., 65, 3 (Goman). In examining rkers the author _ arsenic ab arsenic poisqpwg,. only :1s may be conaidoredj^ s pro Si my pearls, that can ba traviolet light, is cbaracte: iMmo. Straube. Deutsch. zed. ipted to distinguish between eves that those cases showing from arsenic absorption. The an early stage by the use of tter. EXPERIMENTS OH LUNG CHANGES AFTER H. Roploh. rbeltsschuez, pp 144-6 (1939). (German). The author, inreetigating the pneuoonia produoi parties of manganese, had rabbits and mice inhale dust containing 90% dloAda. Of 32 animals, 9 died within the first 19 days, all of which she ire or less pronounced bronchopneumonia. Of the survivors sema ware lnfeo .tranasally with pneunc- cocci and half of them exposed to drafts and cold. >e of those infected survived, end It was la theaa that the lung changes fotSd^are most pronounced; those dusted only hod so lung changes. Since Thomas slafrgatoces pneuaonia la man also, a dust, containing 10% manganese dioxide to Hai^n the slsg dust, was used in continued experiments. About the seme results were obtained, osmely, that thosa infacted with pneumococci showed severe lung changes, that in those not infected the lung changes were not so narked. The author believes that the pnevmonia caused by Thomas slag can possibly be traced to the manganese dioxide. 479 HOTXS ON WRONG WITH BRONZE POWDERS. M. Deribere. Ann. d'Qrg, Pub. Indust, at Soe. 16, 306-7. (1938). (French). Bronze powders, which are composed of salts of oopper, are used In several in dustrial processes. The workers, undar tbs impression that thasa powders are poisonous, tend to ascribe any sickness they experience to this cause. Large loess of copper salts are indeod poisonous; but such doses seldom, if ever, occur industrially. The cogger salts gre rapidly allmlnatad and do not sat up a chronic poisoning wii the body. Reference* Recent Literature - 11 480 TOXICOLOGY or JUXJRIDES. A. 0. Gettler and L. Ellerbrook. An. J. Mad. 3ci., 197. 428-37 (May 1939). The methods of datection and quantitative determination of fluorine In body tissues era explained in detail and tbs normal content of fluorine in many of tbe organa is listed with both values from tbo literature and those found by the authors. Very small amounts of fluorine ore found in normal human tissues (20 to 80 micrograms in 100 grams) and there seems to be no appreciable accumu lation of fluorine in any one of the vital organs. The fluorine content of teoth and bones is higher, being of thg order of 0.01 to 0.03& which probably varies with the amount of fluorine ^^the daily diet. The symptoms of fluorine poisoning are reviewed and an attyro*^p made to estlAate the minimum lethal do3wtyy ingestl^i). Not much at^fjfcion is given to the inhalation of camp of i f 481 CHRONIC FROM THE ROENTGENOLOGICAL STAN Moller. 12. 13-20 (January 1939). (Britisl Chronic la men was discovered in 1931 if|aVttm*dthor was in- vestlgatlng ctory workers and came upon cunw)3$angos in the bones i in a cryolite factory. JM haraoen recognized in before and it that the symptoms in were acutetpNgsgsCctar end included lack of nausea, ti&?pthey dlsapgadzMamnn the individual want into thb^open air. It notM/that thaM^t^n apparent tolerance to the dusts following conti euree^>J&s<Sguclpal sign of fluorine poisoning is in bone changes* e ngy bones. In the affected lndlvld- unis, there was almost of noxmal body structure, the bones of the vertebrae end J^ifjiik^&i^ngJtlaoet e milky white opacity. In the extremities, the compact much thickened and the marrow cav- lties narrowed. The. ted after 2 1/2 years of exposure; more extensive ears. Another feature of the condition eeth. These^hangei inscribed as mottled teeth, have been rec y all countries. H ' tated that because the occur- ranee extensive in sents a reel lust problem, Work phosphorite and ci should, in particular, be extrmae caution. It is lapoi ogists recognize tha in- of fluorine poisoning, and certi indiAgnosia ore given in tha INDUSTRIAL CHLORINE GAS POISONING. Schulze. 3m ergiftaf., 10, 1-2 (January 1939). (Gezaan). - A workar in a sail chemical plant was exposed to ^ gas during the course of an experiment. Although he had broathed only a cunt of the ges, he had to be helped from the room and then lost conedo At the hospital he developed an aenfee, severe bronchitis, and about S er this seemed cured but it again developed a few weeks later. The broutehltl chronic and the patient was troubled with an. increasingly severe cough and Respiratory functions were badly disturbed; vital capacity was only lOOGPcc. and respiratory minute volime was almost double tha noxmal. The oeee la vmusual in that aon- fatal caaea usually do not lead to this chronic condition. 483 UNION CONVSKBICS ON LEAD POISONING. Labor StamAards, 2, 98-0. (April-May 1939). The control of leed poisoning was discussed by the Battery Council of the United XLectrleal, Radio and Machine Workers of America at a meeting in Phila delphia an March 13. An outcome of the nesting was the appointment of standing coMittees to gather detailed information and to conduct further conferences on the subject of occupational diseases. References to Recast Literature - 12 i84 THE EARLY DIAGNOSIS OE ACUTE AMD LATENT PLIMBiaf. ? L. 3dth, 2ai, T. K. Rathwell and 0. E. Keren. Am. J. Clin. Path., 471-508~{1938). Reprints obtainable from the senior author, Jefferson Medical College Hospital, Philadel phia, Pa. The many symptoms that may be found in lead poisoning aro listed and mention is made of the difference in susceptibility to lead. The authors review figures given as normal lead in urine and concentrations in urine of exposed poisoned ( persons. In discussing tha slgniflconsjf of stippled cells, the authors list six teen other pathological conditlona^lJ^Lch these colls have been reported. In thefather's series and experimsnf^Q^twppllng did not precede symptoms and ij the toxl ^eg^*' Reticulocyte response and basophilic dered >te as diagnostic tests. Detailed bloc fents grouped according to clinical mgdreataaaona, differential diagnosis can be madsiraAapKrate arts, cells and fibrin fraction when fferauKred in re- Their analytic method Is /gbr&p?lsi normal sub- doily changes, had no effect '^Lnole blood values, t exercise. It is sijondcant that, in normal in the aorta, bdtf&i'suna of pltabia, serum .015 mg. pgiRLO'mv In chronic poisoning, the feo]gKS!uM lead values are higher than aadroiet, lead will reappear in the 485 THE CLINICAL SIIFICANCE Ann. Int. Med., 12, 1429 The mean number of stip; red cells; in 234 patiMit^lth million. Five patfeutsw to whom Iead^was after symptoms mMsW, but 2250 up exposed to liM^w^rTree of symptoms trationo^B^^fclne hraatln to 2 patlei 5250 aatf\ra9B. These data suggest that diamode? either lead absorption or TBE ERYTHROCYTE.E.H. Falconer. normal adults was 92 par million conditions, it was 363 per stared, bad 19,950 per million toms appeared. In 8 workers cell court was 2100. Adainlsstipplsd cell counts of a is not a specific in- RB2ZKERAH0N IN EXPHUMHTCAL LEAD FO] SOLUBLE LIVS FAC-- DR. M. Lauro, 0. S. dsSacy and A. Artbus. st bid., 130, 642-4 (1939). (French). A brief report of experiments on 55 rabbits given st^lLfforent liver extracts aftar anaala induced by lead. Regeneration of blood^mgan within 3 to 8 days after intravenous injection of the extract and reeche&V~fairly high but sub- noimal leval. Control animals given no extract recoveHB^Sply slightly. Regen eration took plnea regardless of animal's ago, duration o^^gatmast, amount of lead injected, gravity of oaamia and time of liver injectioms^) 487 INFLUENCE OF ACID AND ATXAT.TNE DIETS ON PORPHYRINURIA IN EXPERIMENTAL LEAD POISONDO. A. Capellini. Mod. del Lavoro, 30, 33-43, (1939). (Italian). Three rabbits on an add diet sad three on an iwhimi one were given 30 cc of 3 solution of lead acetate daily for 30 days. Porphyrias in a 24 hr. urine sample of tha animals oa an alkaline diet was 90 , 53 end 106 mlorograas. The corresponding figures for the animals oa add diets ware 187, 136 and 152, but in these latter, the porphyrinuria dropped more quickly *hen tha lead was dis continued. References to Recent Literature - 13 488 LEAD POISONING, LEAD COOTSHT 0? BLOOD AND OF EXCRETA. 3. L. Tompsett and A. B. Andaraon. Lancet, pp. 399-62 (March 11, 1939). (British). : The land content of blood and excrata of 29 caaas of suspected lead poisoning was determined by the sodium diathyldithiocarbonate method, certain improvmaents in which are stated in detail. The investigation confirmed tha opinion that the ostimation of blood-lead is more satisfactory than tha determination of tha ex cretion of lead. Tha upper limit of normality for blood lead is placed as 100 mlcrograms of lead par 100 ml. Whan this limit is exceeded, or if there is a total doily excretion of 1 mg. or mqs^fof lead, than lead poisoning in present. are given of a large terminations mado. Tha concentration^ in tha blood of these tan to twenty times that in the urij less, it/canaot that tha chemical diagnosis of le infalHble is surer than clinical methods. 489 A N9f C. Mahr. Mikrochom., 26, 1939). ( Lead cam be presence of other heavy metal formation of 017 icific lead thiourea tha lead-containing solut 1^ ^ " ^nitrate pr ^10 volume of soil itels is observed I.tat doubly re: is added. After di- microscope. The lead edlelike prims, 20-30 mi- cz^me long and rery ^ Los crossed aad frequently united in star-shaped bundles, ad cam be detected in the pre- sanea of 60-70 ports 1 than 100* of cadmium, arsenic. tin. silver, platlwm The metals of tha smonium sulfide and alkaline earth groups do similar concentrations. The spoclfl- city may be increased ab ous separation of the lead as lead oxide on the plat ting concentration of lead is about 1:40,000. 490 PAINTING PR C. D. Bridges. 77, 44-7, (May 1939). There td?ferent types of pi__ ufactured by numerous firms, and ingredients aro used that x/ tie to determine the toxicity s. Tha safest practice is autions possible when type of paint or lacquer, , exhaust booths are le where it is possible to employ thitf^^A ition la given of the mental principals of exhaust booth conatruatiiSa axhauat ventilation is not applicable, respirators should be worn.Thay pirators, as this type is more efficient aad aor#jcanfo be supplied air rea ls for continued wear. and the air supply la oonveniant. Tha air line slfetid be passed through a filter to remove ftaes, dust, moisture, etc. It should be-timbered that dust respir ators do not proteat against ruses. Paint darmatosei^=dge to allergy to the var ied ingredients, may be controlled by protective clothfilgi^Laad the use of pre- tactive skin rpesms such as vaaoline aad cold oreem, endj^wrentlag the use of solvents for washing. Paint brushing involves axpesure/foV|0 solvents and re quires, primarily, good ventilation. 491 MEDICOLEGAL COMPLICATIONS IN DERCATOLOGT CAUSED BT MASSACSISEXTS WORKMEN'S XJ4PZNSATIOM ACT. J.H. Blaisdell. Arch. Dermatol, fc Syphllol., 39 . 69-80 (January 1939). Tha author shows that tha question of compensation is largely dependant on the interpretation which, since the enactment of tha compensation act, has became evolved through practical experience. Be stresses tha difficulties that arise fer the dermatologist in testifying before a group of lay rofareas boceuso :f tbs impossibility of always giving s definite Tea* or *So* answer. Ss gives consideration to the use of patch teats In avidanes before tha referees. Follow ing these discussions are several suggestions for changes la the present law. References to Stctat Literature - 14 498 CT7IAN8D0S EDPTIOMS AMONG INDUSTRIAL NOEDRS. J. 0. Donning. Arch. Dexmst. Syphilol.i 39, 12-32 (January 1939). The author prostata a largo aaas of Important data relatlvo to industrial derma- teaas, taken from a study of 2000 easts. Ha has many tables which boor careful study by those interested in the subject. Prevention and diagnosis of deimato- sls coses are anich cheaper than neglect. A process should not be condoned as dangerous because one or a few workers are peculiarly sensitive. The largest nuaber of coses occurred in young untrained workers between the ages of 20 and 23 and the bands were the aost frequently involved ores of the body. There is an interesting discussion of the dd^tWnution of dersatosas according to occupa- tionsi^and thara are excellent suBMrtec'of important contacts, aatorlols us< and baarteteristi^effects < qjfrerent occupations. In discussing prjjv^ tion hgrjrtrasssf^ra imporXdiKeOof dstoctlng and eliminating hazards, tanee otf^a^hnniCa3^fa^WMv*aa importance of gloves, and protoctiv* and oress^^^Cha wjMriyn little value in pre amployment patck^S f' ha dis cusses the^^o^s^p3^i proper evaluation of the tests as occupa tional expoi 493 DOT TO R. Poerster , fc Syphilol., uary 1939). m foetoriea uslnc^pZtg^ 4nd tar products. Host of thsvuutaneous lasloi found JjagmSlrtwho handled pitch or pitch products and who ware 4 Patch teats were performed on 14 pitch workers and 6 $ different fractions of the pitch and tar* and the exposed to radiation of various wavelengths. Seme of the chm^cal and physical properties of ths pitch ora discussed in detj ^ studies, the authors conclude that pitch dermatitis and v. ;ha pteRkti of true photosensltlzatlon and not of allergic n of prtdispoeitlipn. This photosensltlzatlon occurs through local exoMmftrijhctlvlty of~a" spec tosensltlzer. The tests re- vaalod that nc^ pau^ffar fraction of 'the pitch^ distillate of the tor can be hold respojuJCTe jn the production oXLpfiot tion. The aost important mdiatiaa^r^jrfc in tha range of blue' ^ visible light and in ths long^mfv^teqgtha of ultraviolet light ( ms). Ths most active to hydrocarbon la pitch, name which has fluorescent 2300 and 3800 Angstroms, is prob the photosensitizing Lents. *^> OIL DB3CATITI3. Anonymous. Safety Sng., 77, The article reports on umm researches carried outdm^dermatltis from cutting oils, about which tha following ooncluslons aro draimy>Tha oil Itself is not the dlreet cause of the skin irritation; rather it is ^he^dust and baotaris for which the oil forma a suitable vehicle. Tha bacteria aagsrjtpt from tha oil, but are on the akin; all cutting oils are capable of penatratugRthe skin surfaces and the bacteria eater by thin neons. These bacteria olse^f&i entry to tbs aids through minute, cuts node by metallic porticlea in suepdf^on in ths oils. Prevention is bant accomplished by thorough cleanliness. The affected parte should be washed twice a day in soap and water end no oils or gasoline should be used to remove dirt. 495 AIXALI EZMA, ITS DSVBARIBCF AND FREVTWION, UTS SOCIAL RERRBCX TO ICCTON 3QAPS (PRAGUEAN, SATINA). H.T.Sohrwus. Nad. Volt., 13, 882-5, (1939). (German). The author consldara that usually la hypersensitivity to alkalies, no real aller glo bypersansitlvlty is present, but am iMediate sannitlvity brought on by =han leal and pfayslco-obaieal reactions. Only prolonged contacts are invariably effective. Since eczemas are only exacerbated by alkaline soaps, special alkali-free soaps such as "Fraeutan" are recommended. Refarancaa to Recent Literature - is 496 CHROMIC GBAKGLQMA Df XMDQ9TKLAL DBBCASOLOOT. H. X. Miller. Arch. Duut. k Syphilol., 39, 33-44 (January 1939). In 3000 patienta examined for the industrial responsibility of their eruption the author food 26 with chronic granulomata of wblob 16 ware syphilis, 9 were cutaneous tuberculosis, 1 blastomycosis, 1 actinomycosis, and 3 ware leprosy. The role whleh each plays in these cases is discussed briefly. When chancres develop in the sites of industrial injuries, tbs carrier of insurance oust pro vide treatment. The localization of lesions of secondary syphilis is rarely in fluenced by treuse, but the lesions of late and latent syphilis nay often local ize on tbs sites of injury and will therefore b important la the evaluation of industrial dezaatoses. Miller warnS^&rslclass diagnosing and treating indus- trlalxdeznatoses to be on tbs lodfitatjnr tuberculous chancres since he beliei thh^tj^idsmee wijJL rise in tjhg fu^jjrw due to the definite decrease in earlj no: - - * _________ 497 THX 1MD0BTRLAL 1HBCAT0SB. S. 9. (May 1939). records will provide a neens foru^thtofding the lnci- to consider producing aatarl daznatoses and relate sueh lndimsnoroccupatlons or oynest ezaninatlons ecbA nalfir to afford an oppor- to reaction type aatwle the physician to ad- author dlscusMa the important practical rkars who^SrdJMlv to be exposed to deznato- 498 HEauams men mm COTXHZC ACID. B. M. Watrous. J. Am. Med. Assoc., 112. 2138 Nicotinic acid has comparatively inert substance aside from its specific effs > Patients here, however, noticed a sensation of waist following oral or Intravenous ad- ministration. Lb Nstorles are presented which indicate that nicotlniQ^Uxd>ir capable of producj ,ent dezmatltls in certain persons worl^ig^fn nicotinic acldtdhletl the course of their nanufac- ture. all of tbs 4 cases present* affected parts of the skin had.<tA^&earance of a slid sunburn and itching sensation, 1 cases the condition subaid or two. Only a wall pro- n of the workers experienced these" ;lc ASEPTIC MBCROSZS OF BOMB. I. XHTARCZZOM OP DXSKASS RE5QLTD)3 Of BBAPSQLJSD AS) CiLCXIXXD ARIAS Dl DOORMANS. S. C. Eahlstrcm, C. C. Burton, and 0. B. .Sung. t Qyn.* k Obet., 68, 129-46 (Pebruary 1999). ' "" Caisson disease (oaspresaed air disease) Is tbs redpAt^of tissue injury caused by nltrogamwhich cases eat of solution in the blood^ritbody fluids in the form of bubbles following' too rapid decompression eftor axpewma to Increased pressure Because of the greater solubility of nitrogen in fats, tiggfetlsauea with a high fat content era sites of predilection for bubble foza*tlon^d)The tendency for bubble fometlon to occur in the spinel cord, the nerves, Ad the subcutaneous tissue is thus explained and has often been desortbed. However, with the ex ception of a single case, reported is 1688, there is no report on the patholog ical findings in the bones sad joints in caisson disease. The present paper describes 4 cases of compressed air lllncee la which extensive bone and Joint changes are food. The case# are wall presented, with complete case bistorles, x-ray sad autopsy mattrial, sad Illustrations. It is not improbable that as s result of tha findings, bone ad Joint changes attributable to this disease will come to be regarded as a oompensohle occupational disease, end acre attention will bo paid to tho prevention and early treaoemt of the condition. References to Recent Literature - 16 500 CQMFHBSSP AIR DISEASE IK BUILDDC TEE HEICS AOTO ROAD "SAVttBRWKE-inBlJER" AS TH1 SOOIBBBf TABQ3NT 07 THE H28LIN RIIO. R. Eonlg. Munch. ned. Wchnschr., 86, 3?0-3 (1939). (Genoa). Tfc* author, an pexaanent medical supervisor of the conpreased air work which reached a depth of 30 asters water gage, was always present during construction. HC presents three Interesting case histories and general data on the symptoms observed. It Is of Interest that in recanpresslon. Improvement took piece at 2 to 3 asters water gage. .13 MEDIA: ITS ALLEVIATION. tOH BT THE INHALATION 07 HELIUM V. R. Lovelaoe, C. W. MaW^Sd' M. Boothby*. Proe. Staff Meetings, (febrrgpq^, 939). Lve complaint of airplane pilots cad descent 1m flight. This Is duo which causes tt to tend to remain unless efforts or other measures are mpwved^to open it equalizing pressure in ttdrml^Be ear. It has that helium-oxygen sixties psemint or greatly di- suggeeted that, equipped with in- nixtures be iqWdSa ptfing narked changes In so2 nmrvm/AL variations BIOS ALTITUDE. A. Bays, B.H. V. Matthews, W. E Tubes, Proe. Boy. Soe., 126. Series B, 1-24 (September 1938). ( Individuals differ nark to adjust to the rarefied air of high altitude, and this related to a maker of measurable characteristics at s normal man between the ages of 29 and 44, habituated tc t youth, alow pulse, low-normal blood oxygen canefty^bw alveol , high alvoolar-carbon di- o^de pressuNM^pgh alkaline reseff4>at hm^Aeval are favorable for accli- aatlzatlovm^^uraltltude. It is * * <& careful cbeervatlon over a nvmber trained observers cation as to relative Sf accllaatixation than any s yet devised. COM TO TBE MKEABXSM OP A2APTAHC TO HCOE T3MPZRA- Shezovatova. Bull. Biol, at 6. 671-4, (1938). '(Russian). Single or repetitive exposure of dogs to beet (30^$t)decreessd gastric secretion in response to a particular food stimulus, and lariepeifed the organic components of the juioe; the lnorgenlo components rwalnert praownlly unchanged. The ob served ebamgse Indicate the pertlclpetloa of both the"ne^ye-rflsx and neuro- chemical regulating systems. 504 HEAT 9Z9QO AS ALLIS OOMDZTIQNS. T. B. Nicholls. J. Mod. Corp. 72. 73-84 (7ebrusry 1939). (British). ^ A review of the aubjeot, written eepeolally for aav In tha tropics, The uso of salt in the author** group reduced heat stroke to sore. 903 OBSBVJffXONB OM THE BLOOD 07 VQHDffil XXPOSB TO BUB TSPBA10BB. P.L. McLain and B.S. Montgomery. 7. dim. Invest., 17, 417-22 (1938). Observations am a control group of 43 workers in hot industrlos sad 30 patients admitted to a hospital for heat symptoms. In the latter group there were 17 oases of heat emps, 6 of heat exhaustion sad 7 of host retention ("stroke"). Careful blood tests ware made; in the eemtrols there was de^dretlon sad fall of blood sugar folloeiag work; in the patients, the changes depended on the type of beet s11sent Involved. References to Racist Literature - 17 506 SSAZDB AMD 7BRZLAZQIG 3!3IBG FDR PHYSICAL COMPORT. A. Bindley. J. Inst. Heat. b Tamfc. Engrs. London., 7j 3-42 (March 1939). (British). In this short paper the author gives a sound and interesting discussion of heat- iac and ventilating system in relation to hrnan comfort. Ha regards as tho main essaatials-tfor sedantary workers in Great Britain), a tmperature of 64 to 68P. i a Moderate relative bimidity, clean air, and adequate air movement; ha later refers to the desirability of variable air currents rather than a uniform and monotonous rata of movement. The^autbor concludes that, in Great Britain, except for certain industrial purpoawl air conditioning is overratod, and the air washer and refrigerator dispensed with, substituting for vej lntpk purposes only a largervoi\tt' of fresh air and asking provision created joir noftemt to b*40ml as required. 507 Dec mb Over 7600' during 193 eat for, various operations appliances are glv< Soma Office, factory Departme reported to the factory I: Groat Britain ents reported are probably causing dlsable- total number of eye ac ts^tS not known but this rhood of 100, Tba loaflet deals with dents. portable), helmets, as, arej^^fd to. and the requirements for tba maintenance of protective 506 CBDCECAL MDSCU CHAHOB mod., 17, 76-66 (1939). In enlmnls experiment finds dmlnerelizatij aim, and potass after tho end QjTBgp&Gre to electricity. TRAUCA. G. Montmesrtini. folia with an electric current, tha author n and alteration in calcium, mngae- uru to normal, however, some tine BI PORT Instn. Min. Engrs. s have clearly established t by the rubbing of blunt picks ught that the meehamim of tha ignl tioa, soma of the pyrlte is reduced to a 200 and 300C. Within this range of tampers' pyrlta proceeds rapidly and ultimately flame (b flaw Ignites the firedamp. G. Allsop and R. 7. (februory 1939). (British), aixtures can easily be against pyrites, and it Under the rubbing heated to between ax&t^)oa of tho powdered sulfur) appears. This ^^ V 510 DOCQMSRS OP OCCaPAHOEAL ANTHRAX. Med. du travail, ~ 40-66 (1939). (french), French rules regarding compensation of anthrax as am tional disease and its foxmar iwpeuisfluu as an accident, are repsodueed ecuesed. Inetruc- tioae for the prevention of the disease are also inel _ author reports on two oases treated with serum and with fomentations of seftoplix (paraalno- pbenil-eulfamid) Ss also mentions eight other cases treated by Murteanu and Zaltzman with other eulfamide. 511 PROPHYLAXIS Of MZHBS* A*XL0OT0ML\SI3 01 191 LOIRE VALLXT. C. Garin and S. Roman. Ann. d'hyg. pub. lad. soc., pp. 96-66 (februezy 1939). (french). In franca, ulnars* eskyloetomlasis (also niasre' metis or tunnel anmaia) is a compensable disease. It can be prevented by keeping the mines as free as possible of woxm larvae and by examining and treating the workers. An intensive References to Recent Literature - 18 effort ms aad la two nines *ployisg 4900 ana. Tlx* percentage of infaatad ^en, crying widaly from pit to pit, was found to range from 10 t,o 68)1. of the infoatod workers treated with tetrachlorotiqrlana, 80)1 were entirely freed of parasites; chenopodiun oil and thy*cl were not aore than 50)1 offoctire and quinacrine was useless. Final examination showed the infestation to hare dropped markedly in all groups although it had not been completely wiped out. 512 DISEASE IN COAL MINERS. V. Z. is. 3rlt. Med. 7., pp. 603-5 (March 23, II. CLINICAL PASHJLOOT. adden. Ibid. pp. 605-7. (British). ralance of Veil's disease shown by the six cases reported pth Vales coal nine: items were typical; jaundice, ns; uscular pains. One of the oases was fnj case by sexological investigation and bptoaplra. Laboratory imrastlgatlons<d$it\h4'out in of blood examinations, blood counts, rtKlnCwxaminations, Vessemum reactions, anliiml IfriiTnjtTiiii expert.- ns, and the presence of urine oi&wlbla, urobilinogen ten worked together and aANworkVd in wet places in- eps iM^Ehlmg taken to rid thesis#* of rata, as no further neKrnnlng done so. 513 ICHBEAL JADNDICZ or A VASAL CASK IS A 71SB. M. V. fltOXL. 219-29 (March 1939). This is said to be the Veil's disease (see Abstreot 433, 1939) la this comtry described along with rery careful laboratory tests. Urine itlent's sdnittanco to the hospital was Injected Into a gulM jaundice on the 12th day and died within 24 hrs. On MSbife to be swarming with typical lentoepirae, wMcm/s 11rer and were abundant in the /zubuZmt oplthplfom^, Asecond guinea pg, ,ated with the urine of the first, also /ujA^yuoroacoplcally aojiplrcc were risible in tho patient's urine or^kthwr guinea pigs' blood or" LUZNCIHr SIBCZFTXBQJTT 0? Dia&IB INJUHT. Carl tram end P. V. Zimmerman. Contrib. Institute. 10, 135- (Januory-M*reh 1939). 'From a renew of the literature and new experq^ttel of the action of sulphur dioxide on plants has been lncree of the conclusions aade are as follows: (1) plants are more realstan peraturea below 40V.; (21 resistance generally [phur dlo^ds at tBa wlth an increase in the relatlr* hiaddity, (3) plants grown with an _____ Ly of eetar are nore susceptible then those with an inadequate supply, (4) grown in poor soil are aare sueoeptlhle then plants in good soil, (9) rs_ (as a heavy shade) below 39)1 decrees#* the resistance, in light intensity young plants are nor* resistant than older ones. A second payer on the subject)la to follow et a latar data. ToT. r. FOUNDATION FACTS . u Tbla nw.|tt.r la la*ud raontkly to mombtr coapaaiaa uid trad* iiooeutiom afliiaud with Air Hnp.n. Foundation. Iu purpota n to report Foundation nawp *nd actlritiaa. Air Hrrunt Foundation la * partaarahlp o( Induitry and etaaea ornalsad to protoot the health of the i| otillioa workmen 1* deary Induatry. EXHIBIT cL September, isoa J Arc You Missing Any Bets? A safety engineer In a company- iliated with Air Hygiene Foundation -Mas recently obliged to design some exhaust ent. He spent much time and effort looking up-date, none of which prov pful. After the installation was pletod --*.<^th consid ty^ytf the engineor chanced upon two of Foundat lont%^4hgia "Design of Exhaust Hoods" and "Design, Work for Exha ained: "Why ell me about these bulletins?" what I wanted!* Tho b dust on soaeo know his Foundatte ords. jiilable in hla organization i, gathering neor didn't know such bed el existed, didn't e Foundatloni didnj what serrices the Costly coaes Director, urges Foundation n. Dr. H.B. Keller, Managing a. the value of their anbershl^a. Inform all interested indlvi of your MBbership in Air Qygicne Foundation and tho serrices through this membership. A circular describing these serrices i onnl copies srs arailable for distrf---- bution through your orgoni board posting, etc. Incidentally, do you hare a complete file Publication lists are furnished upon request. (See J pp. 324-25, for a good account of the Foundation's ies during th^^st Plana Progressing^ ^xus^^etlng arc progressing for the 4th SflgnOA meo at Mellon Institute, Pittsburgh, NorsaJbSJ? X !tion for presentation forces expansion or^w^p: d^'conference this year. The program is being kSyed4;o Mako for Healthy Buslnoss." zSJj of Air Hygiene Foundation wealth of Important a one-day to a two, "Healthy Workmen Technical data include: Reports on Foundation^^engineering research at Harvard by Philip Drinker, Chairman of the Preventive Engineering Committoe; reports on Foundation's medical research at The Saranao Laboratorj^Mj^JJniversity of Pennsyl vania by Dr. L.U. Gardner end Dr. E.P. Pendergrass, rospooti^^. Reports on latest dovolopoents in employee health protoctioa by Dr. A.J. Lanza , ei^Lxman of Modical Committee. Dr. Lanza will also preside at a symposiw oa absenteeism which vrf.ll develop measures for uso of mcmbor companies in reducing lost time through illness. A On the side, Andrew Fletcher, Vice Proeident of St. Joseph Load Company, will point out specific duller-aad-cents savings resulting from proper health precautions. V.P. Aheam, Executive Secretary, National Industrial Sand Association, is to preside at a forum designed to show tho importance of employes health in all employer-employee relationships, the impact of health on labor and community relations. Theodore C. Waters of the Foundation's Legal Comitteo will discuss legal trends and developments of 1939 affecting industrial hygiene. Aim HVOilNC QUkiniF*nM