Document kem6xQzyarE8NE4qYDyRmREO

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CO a; a CC CC 1 : o co a O' !c* o CO CC'CO'O o-ooo OO O Ojo COCriO HOf^OHC I HOHOWClWOWCW -fOWO--'- *-< O O o o o o o o tL'i , o o oo o 0 0:0 o O; o a ! o 0 0:0 CO O O o o Ol o o ! o Oo o coo 0 o 0 0:0 o o1 o 0 o u.lev o CVJ O CM OiCVJ o cy evj o <v o <v OOJCCMOWe fvo WO CM W OIOJ c ojO HO + *H HOHOHOHOHOH ; -i tv I UJ'*0 in i *0 id- if :r^ ISO |Sf St tT 05 IS fw if p d CM N ir* dd d in sC N C' N N h* N N- d d * St St d d -t M lO i in r Kfi O' <0 d d d d d d d d 4* d 0v d cv O' d o DUP050309782 r HAT LEAD FEEDING STUDY __ STUDY ____RESPONSE 3______________________ ___________________ PAGEI ; I; woncool'O cocwc^oycd-ca'otfc?' oiir csnc ciroco^cco O O st C vD r- c r** o o` ;! o .; o' oioo:oo;o:oio o o o o o o o!o o o; o o o'o o o ; o. c o o o o o o HOHO^OlHOrlOHO -4 to <Vi rc * 4 CM K) *H CV ^ fit- a- -d- st o o iio 9 iO k st i3n- 11*6 \& ar** st OCC' tCerr o mo H ion iCOnM mo mSot ;oin |m o in ion -co Of* - <-* - 40 iif) cv in in iO *-< iO in CO 0* - w mm ;n O DU PO 50309783 j*e5--rr o i i \ J / 3 __________________________ s t u q y ____s t u q y X _____ r_ / s z s / K \ t . / \ q / / X J l.Q O O Q O i i * X* * o :cc o cc c o o i off offotff o ffoc^o ffooooo{ooooooioo-<oHo!HoHo-tow <v o cv o cvj o ev 00009000 0:000 OHIOHOHOHOHOIK O O OX O o Oi o o a 0 00 00 0=00 0' o o a O O O ooloo 0;OOQiO a o o o o o. o o o; O O O: o o __ O O OjO O O'O O OjO o o'o O OjO -f O 0*-0;-<0--r0'^0''-tO'-4 *-:*- 3 *-10*^0 OHOHqHO**OHOHO(VO<VO|(N)OWO<\J O'OJ o c\j o rvonioni CVJ W Hj <\1 -! a a a !a a a fa* a a ,st a* a* a a a ;a a a 1st a a a a a i CVJ ro a iin !*- jco *cny w iO icnvr IICtntf <mV mCVJ Win CVJ in o !< K) ifO n iin cvr K) m ro to in a K> in in fO m vf> Si- <o <n i K> jin o 1in0 ff iinn !o la rH ian CM tan ma ian a m in a m i N eo aa in o in in t. * - DUP050309784 4 vs RESPONSE 3__________________________________________PAGE STUDY l i.o o o o o K \ t LEAD FEEUING s t u q y c cv c lOonoK) cioonco c a'Orf-c s oc citf c d- circnroincirc!ircu','COolcovOc^c!cc\OONo p- c r^- OOOO CO' CO O OOOiOOO aOOOOOiOOO'OOO o (MOOOtyOOOWOOOWOOOWOO0WO0OO.N0OOftJ oOOW'oO.'NOOo WOoOWOoOj.lOftOJOONOOOfliOOii ftI0OCW0OC Wo0O; jt-VO0CW0OOWOOO: -WjoOOftlOOoWOOo'WjOCoeVOCo wOo to OJ JIT5 jin imtn\ K5 .inn & nnOo in myO ir- CC * Xnl ijiinn iinn icnr : O vO X) ,in SO sVD .V > iifi o m in \tn m >n in F-* XvO) o O' ixnD ;\0 in o p- H rin Nrv n p:0- ri=n-P tn IPim pX) O' pin o DUP050309785 4 I I K \ t I..EAL) FEEDING STUDY STUDY ____RESPONSE 3______________________________________pAGE! 3.000(10 I 1 ! ;ha^cNC`Cc o o 0 0 0-0 o o o `fviacMow o cvc occrcoeaco&o^croop o O C CT* O O' o C: o oo 0000 0,000 o o o o oWWo Wo oW oW oW oWWo WW <V}OftlC<\IOWO(VOPJOC\IOWC|PjOWO<\l o o WoO| H CSJ e O otoo* o rH tv o O O wo c -i cv o O o Wo ooooo<ri-c*iop-to H0-<0r40: o e o 1 O O Ol O O O' e ! e s (NIO (VO ftl 0!- OO W O > tSJ H * if if if if :cf if if if if * if if if if it ;if rf if itn in IT jin if> tn in m ;o tv fO if tn \sD f- C lo tv *n if m sO i G iHI cv O !=f in x> CO cc iin CO in ao GO iTJ iO [CD .C CO in CO :cO !f) itr> O' i/) O' O' O' O' iO m in in in !n o in O ;o n In O ID %O0 ic in o o o }ISo o in o V3 o n ! i ! i! 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UJ US > >>M- "-(! JJ MH co m: t < xc oo xc C. u . o> w o o: Uf UJ | KH o UJ. H- H* Ui < < ui Gi X 3 O a vn uJ a ui > aJ -J X X UJ Jl/1 < I- H it O. 5 H* < X U <UO33 C << UO uo| ui; Z2 aa X/X in * * r\ \ 4 DUP050309798 & PAGE K\ T . / \ q FEED INS s t u q y ___ STUDY X RESPONSE 3__________________ ________ in: UJ -j; so'. i lit >0 CC in TO ifC fO oj r- d- o z 0;W*K<\j < bJ r Jl in in -j a u a. in !V aJ irsr 3* z UJ m z a in UJ a: o x UJ S' i -j oj 1> UJ as i i IS I- z lli }~ II L. I c-- o ww ZU -J w! UJ [ a: UJ UJ Uj u. :z tL uJ. K as: I! Q ijJ : ! lin 1/_ l^i. ': j ! . 1 ; ! i ! X LL * * u. 1-- j O _J 12 > K dXU CC Z CC U O -* la. K ajcw UJ O LJ Z w O U. QH < o xI ZIJ)' ; a w oi-' Z Ztfli Sic < <! H .J' j) * t/> .' j i ; ,1033 .2023 .1400 ,2068 i *' rJw in \C c*tn cc 4" CJVvD (V O O *M STANDARD / r r z O F T ) / \ = 9S * CONFIDENCE L IM IT S = STANDARD / r r zr zQ THE DIFFERENCE BETWEEN TWO /M \ NS = LEAST SIGNIFICANT DIFFERENCE (LSD) = .z UJ Jj Hn LCJ -* o lu l/T U -J ZW < s: ur u. H V UJ a* ' .uu. az u. UJ w c; tlDL U. in ' u_ ut S1 U. wit H UJ -JO Z -i * a: uiac ! s o o o -< aZQIU. CC UJ CC w J UJ Z W () xOil O H z as vn < c au-OH z z in X < it -1 < aJ K ;O.K UJ j in m a m j j i i rn K} Ki in cvi Km) ro jio to in C ^ P- K5 rO *o K; r; O -* !* CC c\j in ! !X j UJ im *0 r* JO P* >o \0 m Kj IT \C \C a tv in \D i UJ1 .J S ' ;-J \>: jJ j laJ LJ 1-1 -1 1 Is CD In. CL l | o *K n K j} DUP050309799 I U\ T . / \ q FEEDING STUDY s t u q y I RESPONSE 3__________________________________________PAGE J) fO j 1 sC *c * OJ in rf CNJ in ; : i ito o !iO !U1 *> o im 1 1 i I1 i H !*> o r- in cc c co KJ PsJ sfi c O C af CO H esj --t eg .. . i i | in zi <l tiii s j 1 j 1. 1 i ui! >-c io o < >c lO o o r- IO lO CO ar OJ 10 CC as --< n tn <r Lu x o 3 H Ui UJ 3 J- (1 UI u j in zCJ -J ~ UcJ: lu LsJ U *1 u. z U. LU Z *-* <r < ticu U1 u. !s n ' u. K X *- Hh Q Li. --e Ll_ 1-- O JO Z sr jJ 0 U o Li O ^ CC & ac u. CC UJ 2 J2 Q now z x in <D< oz ucz ti-n < e < H- n K uj in p* i/> j . jQfO r- o K) sO o CSC i)in c o o w rv in * * <VJ i ,<* , ; a' e r- r*-l o sO OsO ar e so m K o o <K *) O' 1 i j ; <H i ! (M ; NK OMO HsO OvD *0 a*- OsO IO ( d* mneo * * | T-i i | i <& : i-4 i | i 10 C |w t w O! j in c sO SO Oi com H <H O : <v i , !z o - K < o: w z Ui z W-t 1-- * Ui M K -J -J iJ %> > ' UJ JJ 35 3 CL 3. in o*> nno oO IOIQ o cc to coin G o<v, WCNt! 1 1 i i ! w <H| or- r-* o o OiO sO o. *H so om oaf r-inr- <VJ tr oo o o o c a ein o otn j \' in in r1 * * -t sO ; oc lOh c o o K)>OC o e CCr -4 O o C OPU> * * C\i o OIO oort in in O OIO wee ClflC W O onj in o c r-r- o K5 sO sO O ro in -4 SO O C3 CM sj- to * * tn H oo o o oo o n *K if: O' in n V > o io SO ^ V > in (V CM st m so 4 * n ji z r UJ s o z UJ UJ sr H II UJ a Ui l/i (J J Z-- dJ CL U \; u M L. z u. ur Z ) a: < II Q UJ UJ . z m U Ur < l- ^ o Z U. JH j. K OJ o z < UJ r o a: zo o O DC 'JL or ui o U2 - IT cii. C *-< z z s n < zD U> o yz ui * 2R < <c in cr- -n - UJ A -J ! i ! ! i > 1 : i i i 1 i DUP050309800 K \ t LEAD FEEOTNG STUDY STUDY x RESPONSE 3__________ _______________ PAGE sO K> (O' tOf o tOO st CO rc vC to St o o in o o in o' o ^j Ui s X ui. ui Ji 4/> oI o; fOi H| *tTooO ?too.;j o to m i! 1j o c in sC *0 *0 t/> **4<(W0 o <si o* TO tKo) N in z c Ui J o 3C c a- o frOiO 4ft CO *H r** \C o OJ W UJ Jk < Ui 2E X o 2 Ui J?; a H II I Ui 03 -- a Ui 4/1 O J z~ UJ 2: Li, UJ u ii Li. 2 L. UL_J Z w ec < H;QIU UJ u. : iftlui io. h|I w q lr ) IU. *O -ijo Z CCkiicr o o UIO * tac Z-ce &. CE UJiCC -* Ui 3:Ui 2 iW OU-iO a: z ix n <o;< O z !q K 2 jz u> . M < < wH- 9Ir>t wH* _ai) o DUP050309801 STUDY I __ RESPONSE 3 __________________________ KflT LEAD FEEDING STUDY pft(jE fO r-1 n: t/> Ko -J a 5/J z < LiJ ;CC s: S <: *- <\i n * m;Uai ro JJ 3 UU1 2. > > < bj U 1 W 11 2 w ca "* O u in 2 to _J o c. >* to DU PO 503 09 802 CO 4- H + H M I -n I I ! 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W U> UJ o ar? o u < H* ix. cc > in zc o < o oc 2J JUlh u. or J J Z O LLf UUJ UkJ UKUi UJ o -o o r 2Z Z Z w WMOlt <r < a 2X.Z StL H <0T-Kam HH a: < t i- *IU > in CMS Z -4 W O' TO .J O N K> t-1 o ClL u- O < M UJ >o UJ o Oo' z> o < zc < K n UJ II n > 1X uJ - K T- O M H ct s ZQ O w ce U. --J n -J KO f2c* M C H2* -J o -1 u ax QC UJ 2K - o a 3Q- u o^ DUP050309807 CHI SUUARfc. = 6 0 ,0 0 (NOT M G N ' FICANT) DUP050309808 IHAT LEAD FEEDING STUDY STUDY RESPONSE 3 PAGE IF .(IU U ) = -2.5960 RESIDUAL FOR HIGHEST VALUE OF X TILDA T FOH SLOPE a 7 7 ,0 9 4 5 STUDENT ZED SLOPE, Y ;B X , (IN T E R C E P T S T CRITICAL - 1.9643 T FOR ALPHA=.05 N - l DEGREES OF FREEDOM DUP050309S09 CELL ) / \ s DUP050309810 in ot-4 ** * ** ***#*' : ** h- W H N wojr- < X CO CVJ 2) so KX * cy uo *i rt oj z' ! ^ U. ' H O' o r* a> to injio i iH ^ f* K) d* *0: O in iff* <v <vj a o vi HI H ! IO o o o oo: o w2 < 2Ui UoJ oIL i>n* -i < 2 aUi-J HXe tU UJ /l! OCZL ' Ifi hi a: l/l -J C JUJ C H. h U> a in ?! uT Si U|I Q<! 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UJ Z >- DC U -O UJ </tUi uu.. < HU- Q U. *-ilU H -UE<JJt O -J'O z < X UilX U O UO vi a z*c u. 3 Ui JX - JOaJZ v- C? CLOw X 2 DC J7 sC C r O O.D H X z<c se z< i<n 'LOJ h- 'JO I*-- iJ VIS'!/) J O' tfi K1 jcO CO COM iOf f--3* 0i3f O O CO o : * II I N 4*10 CD O' if) s> O'- <M C CM if if OOOOfJ UJ * UI Li. vfl O' O >0 H N Olf f D C CM CM tC IP c o o e> X yUiJ <; i UJ -1 o o 3 oo o o CL O ^ !ft -* tfl DUP050309812 STANDARD LRROR OF A MEAN = 9 5 * CONFIDENCE LIM ITS = STANDARD ERROR OF THE DIFFERENCE BETWEEN TWO MEANS = LEAST SIGNIFICANT DIFFERENCE (LSD) s .0078 .0154 ,0111 .0218 KAT LEAD FEEDING STUDY___ STUDY X RESPONSE 3 ___________________ r AGE 2 r- a. sf n oj O' d* m IPrj .o r-; }ift !\s CVi ; 'c Cf r-f co m rl w-t CM ooo :lTr :C 1/5 2 < UJ 10 \C o I ll! < vD id HI ea <i>- Q U. U.HO JOZ < iijir o CHJOw z' '2 ce u. 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IO I ID i Ul I " I3 I-- d < ~ *) P- d O' cv rv *v rc *) t CM *0 d U3 I H -4 i--f r-4 O' O H I I H H f\j ! m d- in ^ ST H h* c O' rn CM rr> d to o' M TM rM M % rg M CM H; H **! -4 *) ^4 rg ry -v *) m ry *) *) *0!>0 ! I d-d d d d d d d d : d d d d d d d d in lu O 2 < ft. <3 V 2 O < > uj o Q sr ti m u* -- M *-2 V: O ID I U! <2 i OX < -*; :I. > a<>: ii iO L. . 2C < _j . UJ H _i lii . 'T Li 2 Ul u u XJ 1-4 -i u 2 2 Z-- O la. s u. X UJ ,< o Xu H o p- ,ZPfO c K O' d < n ro > UJ o o cc < -o2 ! n' n ll lf" I- IX Z X I-* * 111. JJ i _1 -J *--xox S }- L*22 -J O O uo :_J ::Dx xw xm h Q. 3 2X0 O -J u DUP050309882 I DUP050309883 io i i ! o o UJ O <L CL O o c o o O o ao tv + H O o a o o a ** tg 1 X. U KT> CL in Li. tr + ! >- O * o _J 3 SL * * <+ ? S' t * >* a z> UJ X* tn H + >*K a* UJ Li u. * < UJ # < j 41 + **** *i ! o v> UJ oz <o H cr o <o > o o o & H [ i i I i ! ! 1 1 ! . * 1 i s ! ! o o o r- i i l ! i ! a o * e o af *tn a * C o o *\ ; + * 4 -4 H* <rH * -4 *-* o eg *-i cc N rsj tv cv M A] * in o K> rO * rf- -e d* 2f 3 'in * o in o j: m o x X X X ah + < c -J h* H- X ~0 <a QIU -J -- UJ Nil fr-- Lii U. iJ X CC U. tii o U. 1C2W M UUJ w UJ D 0 J * <xiu >m q n h ! * H uins ^ zi X UJ CL * - 4fl X -J VI T It o < U. UJ X rvj CL 1w 1 <C Z> Z Oui X K CO W X lL UJ ia i/it- , 90 in ay st Csi CO CO O' w ^ ,c C H It tt II < 0___i o <. J LA - 1-- X ox HU.O w UJ *->- DUP050309884 Lu O< a. *0 o iOn' id 1/1 oz CL Vh1I a: !tn 12 : > o D V c V ffi D LU U u. Q <Ul ' v> z oID O *K <K io 4- QZ <>H c SL>J ifl o 4;HcCr o in N 4t O' CM tfl tO o CO K> 4 V) z < Id ? J Ul. HI *) CM ~4 XCM *S HK) W < >* *) sr cKv -4 >X0*C0M CtffXO C*HM HI CM >JO0 + -n ui o * in O' ;*. CM <c iinn * + '-<N? f *H #tr- rM-D st Ul ? N O 4H o- c i cy CM ' t HH K1 H --f iM -H XJt + *H X * X H tft CM CM wx X X X X ] o + -J Ui DUP050309885 EXPECTED MEAN SQUARE TABLE Put X r * n rrirnTM r CMo UJ < CL UV)l u? o <ec CL 4/J O LeUt l/l 2 < UJ tE ^ U z - as< vc UoJ j O +* w w CM ifi " -* CU IfS -* : t--qr h u + "f LUi CLC. O-CLCLG-'C. C. CI>Ds- X UJ UJ UJ UJ Ui Ui Ui Ui UJ a: ccor & cr oc tr 2o -< OUi ULsJ. o<UJ -J u> uJ H < 3C rpu*>' 5c X20 !' . S. uUii u< V) if < ff ID cs < u u< U^<SoU:J G, DUP050309886 IO ** *# ** #* ** o.s>t* tan c<ry *^o K1/1) AWO <vHc .O I uo<i CL eac):; z<>!. <3\ iOj 2 t/> a ac KO) OD + + +1 + + + Nin(oh^Nh ia/l*.dm'Oh-' O K> iOM nHnOn1c0 g>fi H tf t** H **4rO 1*3 a+ IOT tn it q' ; X: UNWEIGHTEO ANALYSIS OF CELL MEANS in; g 3j Sj mo wo ^o *o>tcn mo moion i0 n0+of0*l '* 0n+9n+ m+ -tf+W<0\0 *r>r* m ifit* 4*(0(\i < uo;' W0Om iInOK*)> CC if) *-t o in H- H m in IU-J UHJ* 1I UI UJ so: 2Z oo o UJ Ui: -J .J or: UJ UJ u >> cr O' ir *K cr 0s \CO 0s *O1 _U>J U-Ji CM-* >" >- -HJ4 - J-< a< o<1 oX co a: x c. a. m -4 >Ju i-dJ UXJ J1JI t 11 (J lO-O <CDr<_> O< Uu BO* *xU-J jUx-J < <t KZ<uX HZ<u Ui 'zJ? 5z0 CL U' c DALA RESPONSE NUMBER 1 i DUP050309887 d n! i iI I i --S I a ft \ J /I RESPONSE s */) UJ -I < iI iV: 2i < ll) s oe in ton N tO d O' \0 C1 0!O h CVJ 10 ION w 2< Li 3. 2 LoJJ o m LJ? O <d\i LJ LO ' <J mJ Z to d o .Ll II ;U 0J1 Lu U II. 2 'L. . ui to c itj!*c" ttuC. <c Lvi idn UJ L. s: 'jOjiij u. K !x ~X * ~lt- * d L- _J|0 h2- a: uiix CuE Oa: UziioOr L.*. a: Li:cr w uJ *q-:. X2o O U.-S M 2i zoisec i/> DUQh 3 a. zr a* z< i</> I i n-- 0iOs.vH>* .aj) G i ! WONiO lOlf-fcO o stot adnf- 4 f0 f\J d ID 2< 2LJ ojr LuJl 3C V- 11 to LaJ o~ d turn cv <J -- <-J it LIXJ: Li U);0 s in ! LJ If .L_iJ:uZ *-H0 n 3;u < o* bJ u. to ajlu. St < *N- Xi-j-< i :i LJ OLD' L. ) U.!|- O -J 0;2<c . < X LOJ COS';KL>* IoXr L2i DEO )L*. uJ Q LJ Z *M QU.QH XJZOX< X Q U QH z<<zm< H- /> H- uJ i/l (Mfl -J 3.8086 LEAST SIGNIFICANT DIFFERENCE (LSD) = 2 O X u X ru CO No OOO'NvNfiMO in ro' o_ OIO*' lKf>JiOt NXT*' z tu DO UILJ O lO vC sC (\J Oo<NvCoOoC it L<.Jjtor- d* KUT15 tfofl:>" UJ u. in co St' *0. \caon?o.oo m do d CM O' * sC in av co in UJ d d d d o -J 9 5 * CONFIDENCE LIM IT S = s STANDARD ERROR OF A MEAN 2Q a EL 0. o o 0*0 04=in0 DUP050309888 I STANDARD ERROR OF THE DIFFERENCE BETWEEN TWO MEANS s 7.4796 5.3861 10,5777 st uqy V \ t . / \ q Q / / q X J s t u q y R\ t . / \ q Q / / q X J s t u q y s t u q y X r / s z s / s : ifO) O IaT ! CM CM to &o ! 1 1 prTnir pfv*l 1 to : jW CM KJ ij 'tOo m to > fO ! CP CHO \ J/ oO Oin' i ` i iwn p* ii-f4 ift p- i eg iH r !!i! i OcM*OH' IO OCO hO' *a w<sIO0*Orpihf--) i j O' to P* mwo CO H iI tf- 1! i <P ; iP sO iz<nc SiL'f O in to O' <0 to oh z u: asJ H li UJ pi c O' O' it iuzUUtarJi IT - ou* U. 2 i21<U/.3 CJ : Kto)i Z UCJ 11 l/) U. )O UJ UaJ: Uiuu.. z O' < *fH- 3x- *C- *H| lu *N u. w : o J o z< i *-r oX E cvc' tU' Z ta' cotrr C Vj wou. H ZIS ou. O W HUl K *a<c uzo Z< ;/) Of- z z in VOfint < t _UJl r z oM o z hU*J zw :.lUW1 i>;* J UJ M iK -J _l :-jU>JlJ i>U-kJJi a21. a25. XO0sJ r-H cC itn\ rH hS-pt O' C\ nrgro Kt5ocop eg ttoO HCtn0 moO oO O' in CVM \0 *H st rg to * X oin H OO 1K0) ttoo m m in m gj -- to tost trKKOo}>N-4 tcOh m SO /Oo) Kro)NiO-H *ttoOh-H- eg ah O in Osf' CM * 3c-am--l inH fO N h- O O W m- fs iHf W -tf1 ^t0 st to CP pto- r* e*-g :i(*nP0 dr tOrOO Proctco r* *oo cwt*oaidn- O' OiHn' ioOnsh0 to o ttoo sf to to a* Hh in cMOsf- *) st tC iMon ontt0Oo * IT) C oOhW O' * J) St -0 ^- to to mr*- P- 10 <ictnco tto#oOo*-' mh mtvJ , mm\Citwtwosot 041 rr4-KKt1o)h- Kttoo5 hw* c? in o- W*O' i ct w ! owm t- m *) ap p0* wm*h) * cP H WCM ti in Z< 2uT; 3Ht Z kaJi 1l&-j uL. - |zxJ cc .: || uU. U. Z *H < a |i3ueJ l/l it! . t-- X t < w >~ : Li. ws U<OJc :. JX aJ uJ uuzOw' Zo a' J QltC XZX <c oo <o ^z a z< - mO' vm- DUP050309889 HAT LEAD FEEDING STUDY STUDY I RESPONSE j PACE O C-K4CJ**s0-Ot crr.>_nmo to 'z 10 i *f*Oo4 oOCi O' vD t ! ?CoM'Az /j K) w tO f- o \> => <C!: c o: in io: f* n if) -o <\i for^-l JO vOi >o %o; %o o:; C Cf| r- >a o o00*(*0o0!;; ~4 0V a- oj >i)JO: rO-H -4 *o to : ; i K7O-* ,1 <U cKLZca UIE! h + Us#-:it H X aJn X Ji N 4K3wvOD i* )0 CTn idf* ; r : offcchsc*-. <sHoOvii;i if) * \cr. too r-- cvoJ* H \0 f- to xfrDo* JJ"HOO ;! CVi IT. ^0 N JO o o cttoco iinnc Oc-' c fO%to <\J 1 JrfOOO CO v*w. n* o \C a tAo.' *-t \! C too ro' CJfOO LA UJ O 2 ai U-Ji -<i < xJ UJv u. D. X** ix a HNH io r- r* io ft*f>- ^'Oj cr invof N It in uz?q\ os hzUJ U-sJ 'I2dr (UJJ !'ar2rJ! 11 !. x' lx Z -W < it o ,X init! uu_. ,<*H--!)X-- 2 SU. lx | o -1 O e id :r ao uzeoe c: u_ a. ja :xi a u. a VC< OO23S<: U2h) O/J' i2<hn; DUP050309890 * G DUP050309891 h a t . / \ q Q / / q X J s t u q y st uqy x r / s z s / s \ J/ HATV ELEADL M FEEDINGE A N S STUDY STUDY 1 RESPONSE_ ri PAGE ! IT. KC3 |* + M +li <O*cn' I ! I +IIIiNCOv*< i fIti in* +I * Ii <fUo IH Ii r** +i cr1 O' ti in * * +iilliI rOo-*' o < O + *f *"l + *H-f ___ SEX _______________________MEANS ir . tmt + ~j ^ H4> H 4H + M + iO*' i in > o KIi <CoJ* +f P- i in iIi iHitn- 4- I CO v II HO * +II t> tft O' ift + *f' )> Io 1 'r- II1:c0v 4* * I *CVJ I ' =* +. H f + tm W + H + M +1st >Kj _________________ ___ PB L E G i DUP050309892 HAT LEAD FEEDING STUDY STUDY RESPONSE SI PAGE 39 _____________MEANS_______ sd' "1 (ft 1O0' + H+ M 4 *-1 -< 4- <4 VK + O* I vft I <3 IH IO I eg + 1I** I iHft I (ft +I * II ecov II oH t r*> + I O' O' 4>>~'4-M+-*+-*4'*~44->~'4'>~`4 4K 4>^ I tft +f O' o 11I Io 4i- eg l 04 II O' 4lI iTIOOt oi k > & i m \o ^" Ol O 4H4H4- +-* + IOft' (ft CO PB_LEVML SEX .. ......................................................................... ................ ..................... TIME -*( t H w <VJ eg cj 4 ) 4 H 4 ) 4 H4 >jj -kil E. sSCSS IS l| i i DUP050309893 HAT LEAD KEEPING STUDY STUDY RESPONSE `iI PAGE i i ft j 1 O' o 4 H 4 4 W 4 M 4 M 4 MH + M ^ W I + I I + 4 s 1 1 j f ft < <0 1 i 1 1O ! <M * 4 1 f** i 1 ft 1 +4 ft 1 4 4* 1 CO 1| Of 10 <\S i <\| -r 1 4 | O' O' ri 1 1 ft I O' 4 H 10 i-t 1 0- -4 1 f f CJ; <\ ro 4 t OJ t eg CM eg * 1 4 OJ 1 1 ft 14 tH f H + H f H H <f>< 4 ft H ft ft h* CO 0* O TIME!* PB LEVEL_________________________ ______ _________ __ T I M E _________________________ _________ * SEX u 1-4 K- ft +W+H 4 ft 4- l-l 4 t-4 4. H <f M H- M 4* *- 4 *-< 4 - 4 O' 1 ft a CO t 4 1O cv 4 1 r- 1 ft H t IT 1 4 4 1 <0 t eg lift $ *4 t0 10 1 r4 ft 1 O' I O' t 1 ft ft 4 O' * ft | 0 1N 1 PJ Oy ft 1 0 K-T*. t*r *4 4 Cv * m ft 1 4 Cy OJ *n * * <g * * I s r-i OJ ( ft K S' 4 M 4 ) 4- >- 4 *4 4 1-4 4 M 4 H 4 K 4 V- 4 ft v4 tr <. r* c 0 c 4 r 1 H 4" < , j ; j 1i c Il l i DUP050309894 STANDARD DEVIATION OBSERVATIONS NUMBER OF CELL CM <M *4 CV <M CM CM CM CM CM CM <V O CV <V 04 CV CM CM i VC ' H *4 --H H *4 -- * M3 'O \0 CT N K> to . CO N 4HC O N Hlfl z * C K O': KS NiT cc tO O' T+ m *m -4 KUO a Xz n sta> stOr N4iSnO n H *4 <jv ;* Jt 04 wcMT c* CMtO *4 CM *4tO *) tocv 4 -ICV <0 Oh O' * (M *4 CM O 4 43 tfl N83 *h O' CM -4 K3 C 4h* st a *4 N N N O' CO i/> CM N h o* h inch o o *4 O O' O CM TO O' to N CM 00 (vo m N ^ *4 *0 CM N O' N cv sto in o O' t tOi CMN st *) ; a n 44-i OIO0V #0 CO o O' tt to *4 in *) sp in CT' OM O CM O' a* co * * * a * t a a 0 N O co W4J; tO 40 C tf) N I0` <M 10 h CV IO 4) K5 to St TO * CM N TO 00 i* 3* ;* 4 c\ 04 to OV 04 (V ft 4 -H CM CM (M 14K)4*<4 *4 04 CM -4 CM 04 t\|44rt CM CV 4 *4 CVJ \0 O' N <0 CM tO N *0*1/1 tnh * d-*4 <) cc C\J 4)tH 4 C h4if)d-S 04 N ffl CM N in (M <\ rP N * -4 CV CM CM *4N O TO CM Off- a* w-itnco *4 OJ ID HOT" tf>4C> to o N CM O'1 O' --f O O' *4 O' *4 tO O' O* O' & O' St ^ CM Ohsfl 45 tOtO cv 10 c< O' c\ Ntt-tfl O'NN *) *4 in o a 10 St^O* O' N --I >0 O' O K) CM O' N --l C>OCIH4IAH Nh O' N<0 m xz so in in so so to to in M0n * ^ i5 co con sf in cr* ovc o * v: O CM CM N 04 * ICV M -*;* *4 a *" * a O CM! to N h --t m *) (Mhh N *4 CV to o* **N * h * O 4 Qtn OJ Sf *) O' Of) IT) oh IfttOO* (VO * weo o to ?o^ cCoV -4 *) vDr :* yz n-ic^ Nto *O NcV i>n0 O45' dc m O' O' to Si H CM *CO N * CM <M tO CM CM N *4 *4| CM O' in CM CM CD CM *4 K? * *4 CM *40 tO CM HI 04 V > ah co cy h- co 43 O O' Jz to 04 TO fs-Kl CO CO a O' a 4-10^00^ SCO hClON OhO^JiO* rO ftj 40 K^JCO HC'Hh *) I HOW ft o* to NHOW O' O' VI 0*4 . O' ON O N O'O' ff O N O to to N CM CO O f *o O' TO O' .0 4tO tO O H O * m *0 -ICO 0f)0 ' -4 <o o sO CM a in *4 O' hN O' TO if j ON CON CO N * *4 4 imn inOto' (V 43 N 45 CM *4 CM N N Hin st O' o o o N TO O' N CM (M CM TO ^-O* -- *4 CV * o *4 N fO CM a >a * N to *- in * nto ec \c tfl O CM G> *4 N d* N st ~i 00 45 *45 flp CNi CM K> C\ nj ^ m c* N O';CM O CM K> CM' 4 IO CM CM st CM O' -4 TO ar O' CM *4 h h in* * CM ft 10 d- N * N hhfil *" N N H4r- ' CELL VARIANCE CELL MEAN CEIL IDENTIFICATION ...... i CMtOchNCOO' 4 WfO * in vd tr c *4 cvj* m o tn N O' O *4 *) tr t xn 4 I O' O -4 CM K3 & :N O' O *4 CMltO 4 H fi oj ru M CM rvl CM tt P4 {\| 4 4; 4 H H H 4 4 4 N M rv f\i:,M *) w M M!\J44H ^ <v *) J() *4 4 *4 4 *4 r4| *4 *4 *4 t 4 *4 4 4 r4 *H HW(l| 04 CM CM CM CM CMICM CM CM CM CM CM' CM CM CM CM CM CM TO TO 0 IO to JOliO IO to to to 'to DUP050309895 <g 4 ifli X> -43 \0 X) *0 >o sj m <49 x? \D V} vO <3 X> X) os x) |X o> X5 x vO *0 '3 \0 \Q <0 <6 X3 tf) '0 'C'OO i/3*A X :** Ntglco4x> o*Kao'AaHmoioONvCiDMHO4in>H^ omin\omHNa ftl to N d-OC0 9i'<fi oto 09K) cr o cr x> m co <\' m vfi ca a in cr h- eg in m 4c> w fO * *K hK Vft)X)HC\O ot r in m cr o wee ma-yifl o co lomiflcoic <r *) *) z~ <g to p* tn o -i x <T HiOWlON ioifOnt) oOwao4)to<' Q?4o* ccrrcoo cr to Ko o z' fitn) wft).r4 r4rd- P^HO* OMP vO in cr Xz <r in in cy CO m cr d- to po VO vo to to p- <M ) z r- cr otoco!r**nx5wofoa*inx)iox> HWWftli^O|HPOHK>{NJW^t<yrtK)4' in rH peg- }' K c*Hr* teog rtHo VftX sr cr co K *z rH ft) *H -4 r. trHfoft) Kri (fgDftN) 4n- rHHHiHOI*OOH<H0 0 rH 0s 4 ft| M cr X> cr cr o 'C^QD ftl fO rH ;)> ift f- x? 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O' UuI | i *) to srltf> r- oooHivn o- mr- *4fl|im 9*H r-eiir o*4 MlO 9|0 r- ftonwn sr lr-<r 0*4 Atm H 4 H *4 *4 HHHlNCVM fll Al AI N N Q| ** f-4!*-4 H *4 *4 *4 j*4 *4 ftl 3JNNNN M MNNHH4 *4 fll ftl Ifll HNNlfll MM N ftl fll IN ftl ft! MM |) MM M ftl fll WQ H 90 on ninnn Xz n nn (i> ooo DUP050309936 te# CS CHI SQUARE = 175,74 IS IG N X F IC \ NT AT THE ,0 5 PROBABILITY LEVEL) A SIGNIFICANT CHI SBO\ R/ 5 T AT l5 T IC iN otC A tE S THAT tHE ACCURACY OF THE UNWEIGHTED ANALYSIS OF ME\ NS MA 4 tU I W '<J W 0 & II I I [ i i64 * I t ' DUP050309938 l `I PAGE RESPONSE 6I AT LEAD FEEDING STUDY STUDY o X JO o l/> o a it fti o o < * U. IU X IO fsia. m D'rtC' fWif OT<O\JOT D- a =r *K OL_<I -- \JftOh f&lTX.O. Tvi! ilLl I- ^ ji . C3) DUP050309939 <c5nS o <sJ UoJ o o m0t >Usi a a. o>- e s lA 16 Z. iOtnoi Ik 3 n ac wizo/1 oo o c2i: <VK * > */4 lOU tOf>' ' +I fo-' Q* tc 4 corv to 1 o NO03' * H& fcivi UJ . Uo-JJ 4^ * ec I oo i; H lo iN HjO1 iO *>0 <N+ : CEJ.L. M^ANS if DUP050309940 Nftl o * * * * * * "4 H m tnotn mcid ^in mw o OC *K m u. CO o<ciNCl u ion Ko)o(a^ 10*010 ooo z ***3j 4> + 4- 4* 4- O 43 CM CO d a *) fO NH rA-iimio coi fm- O O Cl nimo Io<4N0*1 lio < m m K LA CO Cl iFO ui \ J / RESPONSE NUMBER 2---------e ra URTNr PB-------------------UNWErSHTED AM C YSI5"0F CELL MEANS r / s z s / s iw V> oUcl mm torn in <. vs u. m in o+it 4N- a4-d+' tffH mno ^MCMU OW W NO RMO Xz wnn i> i I* i< oD hi KUl U. & (hQOUAil 9o Olli HH hzoi zoUi O aoai i V > n; ic* -MJf -NJ o< o< aX. IaX. H 9O UXl XUi I- H tohci o V) jui u>t.: -I 23 Uxl J a. :V> HO it'll I- <'31 flD SI O u <VCU0 D< uin K a. hOif Z2 Co <o1 zd CzD n R\ t . / \ q Q / / q X s s t u q y st uqy X < i i i i o ki. c t -w DUP050309941 f.-d : ." *>c -- - M <N0 PAGE RAT LEAD FEEDING STUDY STUDY RESPONSE 6I tn ui I J CO < 2 iii a. zui H K 3 tjoo 4* oto rot*o- <c^0r efhc^-oricm>\rs CM ow o UUJi m u. li cc ~Q Zuwi-WnJ UJ Uffi UUI : li u*Uo-..* Uzi usci iii< z UZ__I <C I*Kf-t*j;U)x!-l UIt. )O z UO. MJI'LOL. HZ- trui'zu* OOO N CC Z\cc u. KUI UOi ZoJ Mz *-< to U>-Uiii (aL xOzUi-^QinC4 < o\< oz F<- o*toc!Hz<c* )t<o? Ui rn- Vst>)to i*n) Mnrtoi m ion** XV ; to' ui , ctNryoi*!,W<_J acw ZUi M it c<evgu :;Jui -i KbU3oRJli! II Zula>i:iOwnj DJ OZ-.lii ui;o tl Lt.Z z iMt.iaur: U<J <1 OIUill'. <E HHto UIhJ'H:lUa, z OIt M-JOlLl2<iaOCQ: uU2UsJ KsfOicUKMu U3H JZ15 QU. Q w r zz to <o< QZau* oZihto Hto* tfof'tfo- -UjI LEAST SIGNIFICANT DIFFERENCE (LSD) = STANDARD ERROR OF A MEAN = 95S_CGRFlDENCE_ LTMIT5 s *to- ttoo ttoowp* to uu <) oi z UU0JI r* z*Q > O to tod* tor* to c#r> ionVotiifn UI -J C ^ to H M ON>H h- O' ) z t WWW to rwPO ItoOtoO*O) '\O H *0 W x tUoi -UCIJ MM to O* ) to -iHNIV z UJ if >UI;i >UI J -I oo a K too o ) oto DUP050309942 " ---- 5.6077 11.5353 6,2133 16,2992 STANDARD ERROR OF THE DIFFERENCE BETWEEN TWO MEANS = . IS C' CM d d W r*; : to O' W o* m oj cu CO f- fO to CM r- in 10 O' o *) W O' c in CM* CM m < III V z w 2 O'! i Ui UJ >* . Kl UI IS ^ to <U UUoA d <J -I > * 1: z~ Ui cc: ui 5Q h UJ zw f-: uu.r uz U. UI (A 2<. Hj S <z II w Of O UJ CM' CM Uxi vtuitILU O hlH CO <HKD 5E Sf o U. H* -JOS eiijxu< OUOK kJ KZIXU. -J KUKK UJMOUJZ O U. O'l-t Z KZXIA o < O OQI- UJ z z z < iff < < K U)h- ul O' A J n uJ s>> UJ A a o. ; CM <M d CM to CM in IH d w CMvO If to * I** rt d tn o W W W CM CM W F! CM O' w CMP a Hh d O' f- If: O' t wr- r* CM to dec O CM CM 0 o od CO to O CM OK fO 01 d o* . W SO o o fM CM O CM v O' f* I Ci K rl(t ! of- !Ot CM O [ : Of- IT O' O > O W O' wM 3 d dd co *r f* f-tflrt d f- f- K CM * d CM o CMf- CO wo H H CM CM No- i--nIfin- df* Oo' ioncivn IHf O' in m O' W CM in o c o i d d CM d id - f- !cr <v .* id O' CMf. O' CM CM d W w D f* d O' f*m K* d ! CwMcuw<C Oft 10 Of- f- O Off> O W d o d O' o win woe d HMM M M if-00 or- Id O' iftlNC d I;O*' o o CM If- w o ito d O' W CM <v ><Md O' I-P f- w CM CM I d h- O' d d f- CMfCM CM oc O Oi a O wtfl w .Z M < IK Q hi z in ' t-x :< W ' U. w U. O JO :Z Ui Z o uo K ZCC K UI * Ui Q Ui N Q U. O ac z V Od aoo z< K z<C h- t-- 0* 0s1 o rT <nS V<=?>, (gs- ri vf\ o o o DUP050309943 RftT LEAD PEEDINO STUDY 5TUDY RESPONSE 6I PAGE r ' i 1 i : j ' | j | j * ii Z O w K 1O < Z UJ Z PH i i i l i i j Ul ! Mx *-> 1* j til *-* . 1* j X uJ \f\ X UJ ifi *H O t*o>ton r WN i O* '** <30 WH * (C . * 10 41 hM to o l to to <w*t (4 H Al *10 to to or- to tfl 4> O' to CO * * ri O' <w rH * a to 1 0(0 fOM *tn 4><n HO corn ww to H tu o o o fM N C4 lO N Of O * * O'* HH Of H in ci ca o O' *o o #* O' * h* HH t\i hto * * 0 O' * MO OJM * <* to O' CD HH * * in * O' *o IO* O' in oo (M CM W * O O' m 1 0 in <MO O' W* *10 : to i |<M 1A to O' I i O' tfJCC i * * to eo 1 (V) H ;W * N to o m-- to iij o ; 2 tsi UJ x _J Ul ki < U. --f C UJ UN4 X Ur Q lOCSi* loo o WO' *4 AIMo'S w IO *4 H CM 11 in z < UJ X o * h z tu 3UBl H* n Uto o UJ in u -J z Ul ( Ul UJ u II u. z u. UJ 2 w It -c H UJ Ul u. / wui u. < >M-hx t-t c z U- HU. 1- O JO z r QC UiO o QUO H OCZiT L- K UC H UJ OUi z H QL.Q nc z a: *< O OO u* Z Z * ** < < H- W UJ U> O tfl J : i ; i1 RESPONSE 6I RAT LEAD FEEDING STUDY STUDY Sfc' O ` i_ II ii i i ! 2(6? 1 DUP050309944 RAT LEAD FEEDING STUDY STUDY RESPONSE 6I SYMBOLS USED IN 2 - AND 3-W\ Y MEANS PLOTS -SS9L 10 (O -j i w H K} d'iflO tii - >UJl>xJ>Ui Uki bl IliUkJ JJJ Iii iii *4 tun d-tt)* au ov g tfl 2wy> 3 UJ K C<C o JS 1 DUP050309945 RAT LEAO FEEDING STUDY STUDY I RESPONSE 6 , . 32 *55 O >c fKt!) H -f H 4 H4 I>IItAff0t! 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HI H CO N H ! * o o aeov^|oacy*oaKm* *o> Ko o> a W K |K K eO to a !> >- >- O ^;0 CL 2 ^ jg a *s IN * cc u. co XX > w o2 < Q * * # * * A} i m DUP050309949 HAT LEAD FEEDING STUDY STUDY RESPONSE 6t DUP050309950 K \ t LEAD FEEDING STUDY Is t u q y RESPONSE 6 PAGE as * RESPONSE 6I U0i ' *L hi DZC0L} ho:i z H Wp hu*, JObnon iio Oo wwmnM fO o II h BO eKvJ"coOvItOvteDocinviOto-^tomion HoO'd;icn in jo tooVIo in in i i ooo in ooc jto in i to --cm -jm * p** -< to -*cc otv|!o'oio m o miloo i > to o *+'.o a iio o) X oa i< in m'o m o jin " io wo cwtv w k >w m Rrto wow*4 *Hj h h o h oircn-mo 5 hi **! rn4 %j ZI I ev <V tv <v eg eg <v <v eg ev v tv cv oi ev <v K) to to to j i cov o tCoM, to to *0 *r> to 10 h* 0 CO fO Oto' st H tv a- IO St 3* in *> N 3 if St 3- O' 3 eft in N in m St in in ir> tn ' tn m DUP050309951 HAT LEAD FEEDING STUDY STUDY PAGE RESPONSE 6I RAT LEAD FEEDING STUDY STUDY i 0-4 rHjo pooao to t K o --< w >000 mo o m atots^o^^oitcmcmctn ^ *{ -< l o 4 W oo i o Oo e\jtine ey at Mff w s0c* CM O' m W M j CV P* i \ OOlOOO! *HCC^*-;vOMtf>wcp w*ivD -< *H*- - *H j ^m<,H 1o '- ^ tV <0 >CSJ ,**** * <* * ` * CSS --oo CO fV ?oo*-? V |K> P SJ * C\J \P - <|1Im9 Uc OO*o to wi n w m to tno mO' cv iiC e 0 4- vO in iD <*1 N\D O' N IO r- 4 f- eC r- K --l M >0 it in co. w* DUP050309952 DUP050309953 *#*** -- {"E X PANDED DATA MATRIX IDENTIFICATIONS INPUT DATA ROW NUMBERVO A DED D\ TA "RoSTTOMBERT intCToR LEVELS RAT LEAD FEEDING STUDY STUDY I RESPONSE fi DUP050309954 # 4 Vi ao zo a 1 a CC > z=3 & a> Z S' 03 o z o > ~1 LJ JO .' a ae o z CM CM ^ CM -H CM HOM W tn CM a sr *) a <) a MJ <M a m CVi sO<MH xO ****** **** ******** o O' m rv zK tfiON in acy OfilfO OfO U3 o CM AOtkf)Q^aOvnOntifn)omc0 M3 ) zK O<zV \ {z o * CM* M>*> i* ` oH o O' ol > 4- a OK}Hi CM OH) o * : m inco aa H H ! hn mo: * in *H Wf9 o o K? h CM CM so to a tf> *0 2f p 'j af H ** O00{Q*3>* a*<D 8Q09^*H0 aoHOh-HO f\an.oi m o co a cv 0-<-00-----o----o-0------[-*-----t--o----o----o0---o-0-----0- --;xa0--o-----o----o---w^oor\oj aOC3too kJ O< J oz J < Li a ua < o O *> \0 O O' o o . z oommocMoao o a o < tf) (\l ifi O <\i o <M O^liH CM <M <o o M3tf> O'if a o SO 10 CM H SO *4 5t O CM CsMo; M3 CM CM - -* ss co a H Cf oo o CM CM M3*- O aCM "* i > <M 1 z< ooooaooa OOOOOOOOOOlOOOOOOOOOO : o o;o oooooonooooooooo o moo ooo in o o; o so ooo ooooo U in a o <f oo) >o ooo aM/iotoooioooooooooo 2 r- o io O' o O' O O JO o!o HhOtfi oo 1C oo OlOO ooo o J a a SO CM M a M3 CM d* A CM JO I'D M3 a sf A K N(0 a -J H Hi HHHH'fltV CVIM>l/5fO Li u a *) ?o ;0- to cf in sf *) O' f <y m a if a to o a in * 4f : in CM CM M fO ; s i Q a z o V) a e aec a n z< a z o n a _j < z Q aa x H a z z> kl W Z o CL V) u c a aa O z N o w k) IL h< oU * LI za ! ;CM to >H CM ' z a jcy i C u Q ia a N ar ft a a . -J -J a a ft KM i Li V ;u V !> o ia> < a Z < a a< aa a Z -CO< Xa oz<c tn ::GC CC a< VO M3 tvO *H aoN.. Z a > ao n a M fO:CMKZ z a fn j w JO *C L. a < an w IO na Kfar* :*. iin aX n a 'C n aa i ia <c a cC <J] X a a< au Za , a a ii < n ii zz >id ow D Vai Q !D CZ a aa Z ia zc io M a a na i ! Hilh< z< !" a<>H aN>nz^ tat za HOa n w z< Ua <Q Z ZC M a<n a1c^4 a ii ti > X aMl IL. Iz 1 a< ai/> Fin a ao r c<c aaa D -Jl -<s* <r u{1*-1 < ax ajaoa i r> ceo <ut a :X. __ ffO M x ax:rzatoe a -' .' < a z Li xo aa x n j;-/5 nzo< o <x X J JX ZO J a o c Haioch' h* ' * m K 22 2 o-r o< <) jn p a a a a com U UUHkiC UUUJ a tv M aB oi UU S' Z z Z -H Z oa <a -i K o xrro o: uiki z a z z X x z a*- z a >- n to < t- x a x < z ao n 9a H -* <c o < H* s sr u>k'i OD J * a a < K y c a aa f) a DUP050309955 J ! j CO o o oo <o <v 4 PAGE RESPONSE 6 HAT LEAD FEEDING STUDY STUDY I I i Lf 4 i 4 iS cr 1| oo 4- 4 eC < to < aoo*. O II Ui JKUJ I-Iud u. x a u. 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EL 1EL <L hihihilii a ncE a Zo Q UJt1f % E<C I hi ui mi :u>i aUui :o> -I X I8U iL y> h<U*i U * -I in II M U EL ___UUJGDUI o s*, ^ *&' DUP050309958 HAT LEAD FEEDING STUDY STUDY I RESPONSE 6 m *5 5'U"'.s><R.M30i't 6j Siv .S> *OSv : * * *# *. * # # t<c'; 0 0 K>M a- vO r-cw in cv0 N f- K> f* r- s* <0 ui tc \(3 tfl in **! 8* < ooaq O 3' 0 </) H*+><i+VtJO<H+| in *oi^ rtf-** + o *4 IO Al 0 0 9<< CD hi O< ae in io^ iHnlO)H> o* UI L S' ~ UNWEIGHTED ANALYSIS'OF CELL MEANS a < O <O0 tOn 0wOin tiffin ooo + AlflO in ^V V ) <vcr>"t in <\' <y in* Ohff' r0** o<f*> iHnNA) CM WU > in in U Ui o o UI Ui K IL fei i> a- Htfcg CD CM 1/5 I UI i Ui ce o Ui o -J -i NH << h- I- fI ui hi zz oo U>I U>J UI Ui IN N aM -JH S3 S3 ^ <t EE ec oo r et q. a AH D0 _j ui > !' X -i o \. uint u tt II O O __ <.to 0 < o D- U- D- K >~ < c - I- z z< U <-> un M4 -* ui H <c u4. Hu. zz u M *C4D .1 Sin in Qw UKi t* * UfflNE PB RESPONSE; NUMBER t Ok *m f # ?3 DU PO 50309959 E -i . 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CM I f H j CM I t - + w + - +1 w rt ^ i au*i 10 CM COM *0 o CkMO `!<73 >' tii ss a. DUP050310008 SPEEDiMO&'MOOa; BUSi^tSS FOUv.i. < C i cn in. r\ . i i i \ i ! i i Ziii W DUP05031 0009 ^ STOP n* PATE 13 M R 22___PRI0R1TV D MAN/SEC 752701/B SBna CARDS IN____116__ MAX PAPES___200Ehin TIME tfttn a n n CD W cii o s % I"c VI v> bI < CL UJ %v> zc z w uzs D y ZI6 6* ^ ft DUP050310010 a- in 'C * 4 * * * 44 # :4 ** 4* * 4 4 4 * 4* 4* * !* 4 4 * 11 4 4 * ** * i* 4 4 #4 4 4 * !* 4 * o CM o a CO <O\]OHO CO O *4<M O oo CO eo o a- * * *oio m o^ ch *4 * !4 14 i# 44 4 :* 4 !4 <* s -v jfa*. Cc 11 in oo CO kViI z o CL aL:i t-4 >3 K1M1L Eeg; z o z oH uV)i q f- O m> Ho O ux<z-IIJ i:in>i I-k1 -<UIi X LxJ Uk. U<-Ji xtl Li <z-i aVCMc*ox * nit X<Ui z-J ia- VEQE. 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O Z ZZz h mo |l <Q; z X X X U 4*4 z < F - a: ui k UI H440 <H- s m *x u> m Climff' H ZHff J ONH HiTlfiL H * *O <* K r- o *) u: >Ui O b~* 0 t- 03 a: 0 < 0 z z< 0 1in- 4>4t UI 11 II > LX- H UJ t-a 4-4 4 OQ *X MX K0 iL -1 -J< in -J _i Oz H 4Oa: X:K OSfc i<1n- -.z z -i a 0 ml OUW: -1 -? 0 Z X 0: e u j ui z; j- a. ai u j z a c 0 3-1 O* r DUP050310015 IRAT LEAD FEEDING STUDY STUOY RESPONSE fl m 3 PAGE RAT LEAD FEEDING STUDY STUDY RESPONSE 8I ** ** *#**+ KO < < XkJ SM 1/5 uos ****** ;* i* * \s ## it ! * *** ***#* 0 fco? 0 10 * * < iD -J ~O <t OO a -J +11- ui u ) L h- UuJ U. x au u. 0 ii. H C 2 * 4/5 ui X J *c C X Ui > CMD O *->** ifi * Ui 2 3ir=> fnc.l * i- n i/t * a: 11 Q^ U. LNiOX. J< H-i .<J ^2 iKn Cz> Ou. Ui H* a: 1/5 *- 0 0 0 C + -4 H* i # + *-+ *0 *O O O H o> w a 3* *o in sf a c >0 n Kj r4 d- It II U lu 0. -J O< -i u M ** h 0no x *+ X IL U tU DUP050310017 fe = t 6 PLOT OF TQ.L-REWJS'TmS' STflN&KRO UEVTTI<5n R\ t l-FAU FEEDING STUDY STUDY I RESPONSE Ui U<> CL O-- Ur O24ft CL IUftI o : * io a *> 2,/i QO T M O2 <>-t <> CHf-t oUJ * . M v * ** ** ** + o o *oo +* o mt *wa I/} 2 <UJ o * io + Q m* ICC u-ij o lift iUi u z O9 9 O J -J iUI tu. o O VUJ) oz *< *M * AC * * * * * .+ r !O 4-10 jCo i *; iO +* o0H >0 in z< +; 4 jDOoO Uu-Ij jo IS 'sasE ^ DUP050310018 hi O < 0. EXPECTED MEAN SQUARE TABLE ill 3? KhJ Daftf.l hi tc hXi A #* ^ " U s o OLi a s 1/J o lhuU~Ji CL CW<O C--oM <4>>;~4<*m%If*t' <*H 4* -4- + + a. a i .*. *. *. *. *. * XId UDCl Ifidc hi hKi eWc UKI hKi aU1 >V-) z*id a h -hJi ob. >hi K a< hui CL DO hi ml X &a idn u jX Xh/'i < u J O CL UUS hi *i < a: n DUP050310019 o * ** * K io CM\0 m 0 0 \ O < m Aiioin O M M z u. ec f* 0 10 IT a c> H M au:i < too ionfso.coo so- >o0 o'O vo0 + t + +ioQ<a. => vo> 2< uJ m moH iflfv <o cy O' f + + Hif>fO<fOlO Iiot 15T0 tOn' CM X<)K K XNMf> in 4* Oifl' rG* W bJ J ID <r vZu>i: C rl<>/5l-; U. i : o1* O' *n r- co 33 c- r*ooo + z' ow w4-d+- if> io co oco (MCtf O^4D*'*^W 00C+4M: O *) MOiiXoT' mO' wW *O \MD vO >o 3tn; 0 <0 4 Id V5 5a 2 -> O L Ifl Ui a ,) ; ;?> Q ;-:qv* ? v) |. _ g D UJ Ui tc u Uou *O0' 4* H^inwMIOWCM <n Ui w ac UJ c a: -> LO. uii >UI s iDn! -J X JSSLliiJdI < V if n MUi I1> u 0 u u Xi M <3>* < 3 < in M M uvuct UM. U-.i 5z zo -1 Ln in a Ui K * o 1! ; DUPO 50310020 RAT LEAD FEEDING STUDY STUOY I RFSPONSF A I uo !I in Ui < c Ilf E IItfti <. &Z i- ' wK >* 4n > iCcLo S hi IIOZ IS G Z 1-4 D Ui |! H kUl. L, B < oc ; .\ Sfi 2 UJ !! * ! ii i U5-*Ji D 0. ON O': " O' CO mO st oo 1 o I<OM oO O GO a- p* --* C*-MoG OmJ CM co *) in t^fpiot H *) Or ifl z c UsJ- in <y G*<M* O^ IT o; IT' <V J!; 4itf>'-: D| ID Krj.' <1*'! G; z id -3JPj Vn UJ o UJ V) O -J z^ XUJL 4' ' UJ U u u. z U_ UI Z Htf < 11 D UJ Ui E UHi 3UJ u. U*-.i <) K O U. S K <OJO Z X.X n oKZKoU>-. CL UJ DC *UJO aJZ J-t G XOUZ. DIi^*- <0 T Dz U zOKto i"n yCo* hmuj<J . i i -C*O5CWCs, IiTf' o<rc> st G G O* -*o K) Wz<O It: c 3C -d jc I- H U<Jc ~ co w Ui o O -J Z~ u-1i p- UCfl UI <G UJ u E K ! II W Z in Z UJ H U. 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OH |ft4 n G O' i/> .J DU P050310021 RAT LEAD FEEDING STUDY STUDY RESPONSE 8I PAGE 1Kooft tKo* & to cv o tcou I OCMt-P* MoIhAwN --cot 10 toktoo 10 10 K n H cnto ton to to z S4 OT z* UzI a O' tHo to c Xu ' 11 pr2 toLJ Uu~J u. < wKBf:- o*-* U. xjfj. K O JC3 Z sr to aO wUiebr o *a: 3urrS|c . . uJ 3 UJ Z z oPM K u < Ct UJ K Z >* i UJ uxi; o o o to o e K oe o * to oo to o ^ to.K -St- 3- wcu cr- COO to oo o o CiJ O O O o -4 tno o o <v a*-* to to to :o sr a * cw w to *-4 O O 0-0 coo to o o-o K to o<o o K iosr> cvi cc cv H o to tOlto in | cw O O ti o a jo o O i oc o oolin o H w4 vH(lKto> K-* 'M w cursi tr ^>3- CO ^' itfot*i;s* r&cu ttoocavMjN if to z c 1U f o 36 t- z UJ ui 26 Kll UJ 00*-- iQ uj;to z~ Ui: xu Uib It u.fcz U. UJ > >o> Ui U-Ji 23 23 a CL O 'O Co o f to to DUP050310022 -5 I } *5 I PAGE RESPONSE 8 AT LEAD PEEDINS STUDY STUDY I ! I icv Wm iJr*-iO 4 CO O*1ttf) co n o\iO 00 lO \0:K z oM h <O Z Ut H Z ) i ; ! [ t ? Ui X! H j 1 * CO! O O' O o, Ifi O: ^0 H * i* <M IQ. CM OO CO oo tf>I. 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H f H f H fM W W K> ______________ TIME RESPONSE 8 4 H <f K+H <f H 4>H II II !I I 1w 1t +1 t soh 4I e+ II tf> t +II :* +lIIeto4vf>* t I tI I1 sot +I I to r. M NN <1 t0o + w 4-4Obft K cy n a- STUDY I FEED*IN SGEXS_T_U__D_Y RAT LEAD LEVEL_______ PB * o -J > UJ -J to a. 11j i1 i I I DUP050310026 AT LEAD FEFDTNfi <;Tlinv e-TUPY 1 0 F:pnii<rr K * t LEAD FEEDING STUDY STUDY I RESPONSE A PAGE PB LEVEL T IM E ____________________________ _____ ____ _ TIME___________________________________ ___ * SEX t 4I I t 4H I i. St * #H eg ra w 4 *-< 4 *4 4 *4 4 *N 4 *4 4 4 * W lO t tn uS >iu &a n i ^ 1t i4n *tI O' 4 ? IItI &O .41 ;*40. tIII WO t I to Io iOt O tfl eg DU PO 50310027 IRAT LEAD FEEDING STUDY STUDY RESPONSE 8 & V* L. 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C _O 2Z O< M 2 *" llh < >- m Ui. <t ui -- X HM u >H2 --T WU102 J M O M < ui: J h ' u; s. tluz S<Tuu Ja) ; <; J f< O C JL. 01W ZtL> UJ 06c < 9 i< - u. s> mzc < O' < ce 0 J J ui K u. cc J JZ ': IL. * UJ UJ 'LtUUH UJ Ct -*0 9 3: Z z 2-M Z C MHOU < O 7IIIL <-* z *- 1- E UJ a * --r - < O <C f- > *A l/l K fM CMS d <vw 0Z O' *0J c m 0*- \0 C'U- >-- * * < d -K K U' >O Uf H4 a in: h 0C X: c < 0c z z: < K K! i/t c: >4' if if>: X UJ j - 1- *-o! MM Z s so: 9 (- wffi U. _! -J< e1 0lAJJZ . - 25 WQtKH. XH 01/1) 2 Z JO 9 9W 0J - o .a: ac CC kU UJ z K CL *U ZD. oa O -J U> * i IT ( U' N *-* U) 1 1 UJ a * f< rm -i i UJ i <*> I^ lp 36 | fu 011 ^ , > w 1 Ml UJ 1 35 1^ 10 fX 0i 1^ 0 cc 1 1 u. |K 1/5 11 U J* O DUP050310^8 I uai oz LU CO X< l/l z< UJ X ou. tHf) cn < z<t o Uh>J Xo H S1B11 oz UI X uo. >o*c ex Ou Ui X in bJ M ,: in -j' ; < ;; z* X in UI *U * za l:U< Ugi lit ! ,|t2P 1a-4 1iMn V IL Z-- o >* N1- *W0 UZi in Uol o5 oX is If 3a. +* !!lfl yw* in KU<i t<f5t uX H Z< u z r. DUP050310029 RAT LEAD FEEDING STUDY STUDY RESPONSFI IRAT LEAD FEEDING STUDY STUDY RESPONSE 0 PAGE 8> = i 4 3 & 5 FOR SLOPE = s.4080 CRITICAL = _2 ,3 8 3 9 r / s Xq u \ . Q zr K XJ K / s t v \ . u / zQ x t X. q \ STUDENTI2E0 SLOPEt Y=BX* (IHTFRCEPTrO) T FOR ALPHAs.0 5 , N - i DEGREES OF FREEDOM DUP050310030 IHAT LEAD FEEDING STUDY STUDY RESPONSE 8 PAGE DUP050310031 CE. L MEANS -iff I oO* fftt iDn K5 CO O' d** CO* -0 -- CM 04 ~l C CO :t d*St *> + O+ O* *3 *n lit r* oi IO at <) 04 w?<l NOiO r-4 <HI CM ^ CM CO M> /I z <Lil -1 JUoi LOi, 1l-ftt Li>z<nia Kr (i9t* 3fc Z )3 > C in PL fk Z P KP J(LOD </> i-J i r*f S.-zV 33 ! oE E . ki 5. j 1 U) -1 CD < H* in au:i c 33 ! 4O > +s sO+t +O O4-iiiOni*+aot mo+ iCnM Nm NofF\i)tjoH HatCO tn pHh < uc j* t^o incep*&nKt > 2. O in I z < coy LJ tkUtJ. uo. suOKkcU/5l: o- tO at --:*#*> KM K5 <V* Uitn-i i- LI 13 H-J < Ti hi s o :U s; Oi ->; kO:. aUu:l /? L Ui > Lui Ui' X2 j<iSy3 .Uii * fHO<- tl2tl4ffUl II<KJ US>uf<fi m iU-xJ MU -J aUi 2 hLp M U. PH 2iMs in &z in ** I m I DUPO 50310032 NAT LEAD FEEDING STUDY STUDY RESPONSE fiI fer UJ o Ui < Ift 2 < UJ X It* iVi & UJ SC > I s :a VI iU2 IO [ I l Ift !, O' g la iU im ;s ! ;z 'UJ Ift z CL V) UJ jr oil o; r; >D o o io 0s \D wo If vO W KJ <VKO) a H*H(U N CO & w o ****> ifi 2< . *U2 CVI >n 1ft if) K> V> O in o * H z U ui at H II Ui O: o (VI Id V) ov -) z-- UJ <* CC id H- id O K 11 u. z ! U. bJ , in H z *K <r z < ' < It D UJ UI LL. id in, Sir, LJL. Hi 1- X -* < >-< -v a ; x ; U i-TU. OJOZ fM 2^ 2 <J OU H aaru2i JoXr Li. UI LsJ z M U> i>d xz. . z a se *- w t W oz o zo Hui H<i!f*t L<* i<j a. V Ifl -4 icom^c ,*4aCha<C-i ' * aw* :W ?0 CO S' V) z c u; z o a H* Z id ul HH Ui r> o r ' . H U-J a Z^ w _ia UJ cr ' < in Z (V ill luz UJ a. ui in u. :Z K : z < ( O Id < a ! LJ U. UJ H z vn ' . m HX ;<>- H- D X H ;U 1- U. 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CL oo 0 3 0 - in -< ;ft DUP050310033 STANDARD ERROR OF A MEAN = 9bS CONFIDENCE L IM IT S s STANDARD ERROR OF THE DIFFERENCE BETWEEN TWO MEANS s LEAST SIGNIFICANT DIFFERENCE (LSD) = 13,0403 30,0713 1 8 .4 4 1fl 42.5273 *cz I (SJ ftj CeVg1 cE PAGE RAT I EAD FFFnTNrt c T iin v f t im v r n r r n n iir r RAT LEAD FEEDING STUDY STUDY 1 RESPONSE A iMt C--e kOO 0Oo. -rOg*Oo0N1OWfttODft Hjn eg \m0 %o Orj w CM m *e*g t0 4 JO s* CD OH' CW z< CO ws Ctr\vi d- to N UJ a: o <OK iis < i* < < Hihh J tn^MA ' z o tc Vh-i z izw w X; > Ui UJ -J 23 CL <E K> C k> 43s* teg ^ OJCOk^a- tfi H <0 CNJtOi tosn coo' ev own K a* to eg to *K it tOefg)'^OaNt:c*togOif5o' eg K z* XXz cv CC W0 fOtfl r* <vo* ft ft ft to eg K z eg *oo?o.o*o 4 it -Hi 4 <V (M *4iT C 4 <W (IT JO H eg 3KA atl rf-4 \0 t\l Minir- d- 4 *g<aj to co -Oieo o w to eg ro o o nr to wo o oije;ir*ovj IOoo O oo S> 4if> *4 tt izn c LJ X 3E Z Li L?i Hhf It CD -- iO LTtf UJ Z :~ LU . LC. ijpuJ >1 2 LI. .WS *4 igc < tioi^ Li sL x trttuU >-- X ]>* < * -4*>H- O L. '`Li < a . ' a iu irzUcOc*L4 CC UJ K *4 U131UZ *4 DLO'M * < z o x in D U OH Z< tie ZcV<I h hUJ Ifl 0* ,-J DUP050310034 $ <m % *fotf to (Si fi. I % mz *e ! i I it - ! i PAGE RESPONSE 8 WAT LEAD FEEDING STUDY STUDY I Z a: Id I-- Z u K Ui iKUd)I >0 C <8 1t!^*0oQ-0c4S*-t ' D ;X) "* cj- c 0*0^* O f |aUt AtoAtoI 0o* tr in 3 M hWd** <0 A%I0( np tO<M 4J* <0 *in WN *o ^>c to to* too WMCCKM *o H0 to 1 O; 3 Hu iad:s^ tjS zu---j o ;Z M i< H Q 5f *H 10 ittf ** to :z in id a) <0 1- X in o * CM X O At a> IlLMU. 8h !C JO IW hi ld<dux<i; ac u. w Uui izd hi u ?. aaonuzcoier a id aj ui a ui z H* O !<Ka zDu. x<Ofr** O O t-- Z Zitft >< */> itrr> t* < d> r ui -i ^ * .* tf 4 I i 4m DUP050310035 J* iOun; z> u>J o z1C >/> IRAT LEAD FEEDING STUDY STUDY RESPONSE 8 PAGE DUP050310036 Ir \ t . / \ q FEEDING STUDY STUDY RESPONSE B m <v mOJ VzI hoi<w <Q. x 'o K 4 K 4 H4 \o> I !0 IO 1;,90 +9 tO t* | M 4>Kf ii5? Iw Io 1lIl1f9** +lII.So<M nr- *t ,C*M I +I jtlofnl 1f 9O-4 19 + I, K> I. 9H IO I to hV)i Z D CL VbJI K V> Q3>hvan 5 5ig o hi hi II O* h-Ji K UJ; s -J O CL. +1I r% . 4* w + *-i + ) >9o . 90 I >o I 1>9o I ICC *|4 .*4 iI i(m10 io 9* 4*i|Iii 9eNoer III :-99 IO t sn -f i tin 1 19 II 'o* I .4- 4 -II 44 i jO \n #$ 9# DUP05031 0037 STUDY I \ Q + _ * H + M +M +W CM \C CM 4. m + rt + H+H+H 4 <vi #0 PAGE MEANS TIME RESPONSE 8 I 4> ** *^ * * + O' + H+ I to SI to et II KoO* II +t It +II CM +1Iit111>tl fmrO<*oefo-\'i I1II 1 1 1 1 ^wo s in tIII 1 1I iInff 4 Io I I St +III 4 M 4 H CM + H + *>4 Ii* 4>Mi i4M>Vf wtf tn I" St > U-Ii OQ. * SEX RAT LEAD FEEDING STUDY PB LEVEL. 4 r < i i I V V*/ ` " DUP050310038 RAT LEAD FEEDING STUDY STUDY RESPONSE 8I fc-u 4IIIII "N 4 M fH + ~l 4- *1 I oo I st ft o l 4 fIt tHo III ft Ifo* 4 fIIIt ten I O' fM IO I4 4* r* IiIi Stronut \A N 4tIIft CV1 II O*4' fftt Sf 4I rt fIt 4H- IO 4 H + H + H+ H'f I t 90 N If) fe I i S3 PAGE * SEX PB LEVEL TIME......................................... ............................................ ............. .................TIME___________ lxil to tO & st 4 st 0 44+fIIti i>ctmCr3 < <30 W +| <r*4 4 ft :W> Ift O 4I !* JI 0s N Is H + H + H + H +H+ H + -w1 rSt3 i | ii i I J > f' .I J r '| <* ? i l ,s > , * w DUP050310039 I 4 UDATE MAR 7 2 ___ PRIORITY 0 MAN/SEC 7 5 2 7 0 1 /5 5 8 0 0 CAROS IM 154 MAX PflGtS 200 tNO TIME 1 4 :5 2 :4 2 * ' . # :' ** ***** w cv in o o oo o-l <coov ;<OV COJ O. Wo o^tO .9 9 9 HOiO oe 00 oa* en com 999 ** * ** ** *** 5t \ J / r / s * st uqy X r \ t . / \ q Q / / q X J s t u q y it in -J o* Da 0 *4 u*i o in tIvI * HD.i K* cr a 2- n . zuti zr -J tn XX U>J -i w U>J a8L<uk3.J 2 -H 0 J i2Di- O*o<- # U*. *** ***** N (-1ii uU.l x<r UXJX 2-J Cvi 1>1 W X li/Id}I Ui < CaoV ***** a.:; ccco o-r am. < cc m &(2UiOUt**nfxJJt- (V < * W io*ohz*****n oUooJ Co*****L * 0u_ o N. <Vl uo. --\( 9 OCM o W0 W W CO cvl oW cu cOv O < 0 *O>* CM <u0. 0 X in 9**-t 9 *K 9-e*s:[^0c<enV UOnf JaO> >ft.-; >0.-12 Xo. fe UIZ L |JZ o u**. 1 C# ** ** n N36874.09 DUP050310042 P\ T *) !8 SC -P* INPUT "CRT* HSTKTX (DOES NOT INCLUDE TRANSFORMATIONS) P A T I if An fC rn riM ^ r-T H n v *4 O o oo cu oCM o OIOO oo o 10 o :* o *04 *0!0 ^ o 0 to H O H C WO_ CM K>_OfO J,^ erf o c Moworo o o o o woo^ooojooooo O O *? Q tO \D O I Sf O H H H O "i H ! *j *1 * * ) zw z o; S' 2 P0;0 j* o S O 100:^0 OO o; o *) oO |CV*inH HCWO too^o O o o o a o o o P* >0 !HO Hfl * ^^ - i4 W W Iftl WiCM CM CM on >0 <v r> kP in >0 CD ;-i -* CM jRT CM CM jcu CM CM IM CM n DUP050310043 fej < a. r ;zV X s Q cTtmY i r \ t i pan P FrntN fi cTiinv u V2) O &V} hi a Q 53 oo Mooonooo tf tULftl oHOMon oo o OHK HOo riHCOH O o H O o n ^4*0 Q CM o WhN 0o*0 rrut nj o 5-< d- *) o Nd> *- O o fs. W >0 St o so n pHIOHNH OHOWClOlCiO o o o ao jo o*-<cjho`C,vjc&a<\)ti'oOWCo\J tun 0 K SC fWO < 1&0 o i!Pf*O- *1o0 sftn do* jf! *o =3r tf> st- d if fdv-: co St n DUP050310044 Ra t l e a d f e e d in g s t u d y st udy i r espo nse s pag e 4 EXPANDED.DATA MATRIX (IDENTIFICATION* INPUT DATa RDW NUMBER, EXPANDED DATA r o w n u Mb e r TFACTOR LEVELS) LOG DRAIN PB <0000 I! II It htnH<Oz IW-- O*-z# Z> H iO- X VtA LU K X\ : 0o O' Oi oO o 0V eg Ooicv o e o oo o oDo 0o Oo o OIW ii -j e at in -o oc o* 03 U. < OC < UtO-UOJ- <oh KUiUJ <JJD OiliJUJUi 000 oo ooo V )ooost-oooin DQQz; aZ>. (A (A i:t Z O C X : ) *V ; U. IL XL It I O O O i s > o z<. *# #* W fO BRAIN PB n i ii DUP050310045 kg -JO m IL Z OO ft 1) sUraJo>' ; 3 Li Z t/i CD cj <) cj oi *) eu < CJ W W HHHHHHHHHHHHHHr *- W W W *-4 W| r| H H H H H HH Z o * + *#** * ** * #* ***:*** i ****** ****** ****** * * * > S ^ Hfl H Hf* W ooori* O QNH st M w o h* a ONN o Cl a OO oo oo oo o o o o o o o o a o c o ooo ooo ooo ooo oooooo ooo ooo ooooo oooOoooOrooo ooo c ccc ooo ooc oo oooooooe oaooo o Oo oo OO Oa o o c. ooo c OO o o ooo ooo oooooo -I Id -I O id OQ ft < a z< & i/i o oo o aoa a ooa oaoooa.oo ooo o ooo oa O O j o o Oo o o; Oo o C 3 O O OO C o c oo oa oo o o oc oo ooo ooo Id (J o o oointftotnin a oo o o c o 00:0 o a O O OCl oooo oo ooooooooood o o oo oo oo c ooc oo o ooa oo oooa oooo oo -JUII Z<X-X f<r u <s o sO :> I! _x oooojjoaoooooooooooooao o oo o oo ooo o.o w to; in u> o oo * oK z m o o4> HHH oo oooa oooooo mm o 10 o oo oo ooooo oo oaoo td oo oo oo * Ooo c oooiooc Oo OoOOS;; O Oo<cC in o o *0 O ON O 1*J H- H H --i ooo ooo ooa* ooooooaoo o oo oo o 9 9 4 9 9* ciniooH HH^Mg H oo oo oooo oo o o oooooo oo oo o o o O oa oo ooo oo * <vi o co rt o o ^NfdNHN iCtl \DCl -i ui o OCJHOOO 0{\|HK)0ffl o iH sa in st tn |w *K o <w<) cl w o N eo cl w N CM Li ft V) Li ft; v o 3 *in > Q 3 &z kJ o Uft w H O c u W ui u. z UI Q UI L> :Z ';<ui i; !i ! *4 W W-CM Ctf *V jt\J *- r-t H HNitNl <%j l\j --* -4 -*< -- --* ?VfV M rvl ) '*X WfsjKjroK5i>niofO>OJO^-d-cJ-=r^^G';a#,tnininif)tn:tf>iriin id z < ICE oion ! !N. i Cl CP fetv :> ;Ld o D ift < :C ozM !IHz<- z< ||u 1<Mo>11-X VNiiKdrJ',V^m--2.-* tt < id X >u1;! JH Id fid JOJ4S > a u X*K <5 < use j c o t < JU. H Z ft> Ld O be < o u ; ft I- U. K' > W 20 CO: , < ft; ^ -s UJK u. oc; dQ ijdszidou;! UUUHUQi w <_> u ctr! E Z Z~ Z <s M K OU < D; ft X li *- Z H- t- ft ld ft <! B- tm4 <0 < 3S I IU>W M> IOZ o -* Z xO -J OP\C M 10 Wlx. K Q < > Id O fct < c z < ui it XX > X UJ KKHD H -<i ft S Q O H ft ft -J -l< O u: J JZ I*--* oa a>- x t- h-w - z z -loom o old OfJ^t UI ft UJ o z KZ.Qft. *OUQJ Oo DJ * Li N CL X < if) Ui u x I- u. o > K M UJ z UJ o o X o X ft o u. > UJ , r\ , DUP050310046 TEST FOR HOMOGENEITY OF W ITHIN CELL SAMPLE SIZES CHI SQUARE = 5 .3 3 (NOT SIGNIFICANT) A S IG N IFIC A N T CHI SUARE STATISTIC INDICATES THAT THE ACCURACY OF TK / UNWEIGHTED ANALYSIS zQ ) / \ s ) \ y . / O i ! ! ! r\ . i w 4-yi DUP050310047 J >0 OO o o CO ;4 IRAT LEAD FEEPIN0 STUDY STUDY RESPONSE S PA6E n- !.. 4 4 4 OO E( a) = 1,6083 T FOR SCOPE = 3 .5 9 1 9 T CRITICAL_____= _ 2 ,3 6 3 9 R/ s Xq u \ . Q zr K XJ K / s t VALUE zQ X TILDA STUDENTIZED SLOPE, Y = B X , UNTERCEPTs O) T FOR ALPHAS.OS, N - l DEGREES OF FREEDOM -w DUP050310048 < ..3a hi I 1 \lS &< CL ZUtOJ O CiucnLr > a > => UaJ c >a t<r c z c Kin K (> in z ac > UJ in UJ lL Z<jJ s -UJJ *-c ? + ! n m QdIo2M5 gz-< tf> -^UJ tno ar >oooo 1I 1lt&* <H o io X< O i Vn z c u x. U_-{ii !I O f; * 4 S**i 1 **i o oo 40 rO + CELL M^ANS I DUP050310049 < I! iii CD lit oc <3c *&/> z< Us:i o LKi U LLi ex Li VL)I oaIzD LttJ <LEi < Li Hu X KC iu uoiaa >3D o h-i !%* w |0 PJ sf K *) mH u + + 4- + LI 3QX CXL Li CjbuCiiCuKj a a ala a hi LI Li iLJ Li ESKICK zO- Z o DU Lai s o .> & St! a*<-: LUi a C tc z> ton &D a tn LI X\ ti C_O li u UUliDu Ua-J < U <IU < 33 < cr o .-It. 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Q zr K XJ K / s t v \ . u / zQ x t X. q \ (STUDLNTIZEO SLOPE. Y=BX, INTERCEPTED> T FOR ALPHAr.OS, N - l DEGREES OF FREEDOM I PLOT TIP TE LC MEANS VRS STANDARD DEVIATIONS CELL MEANS 14 o < a in m tn 0 to CW in 14 t/i oZ a 14 ift Z ao IX- < m o< Lf> m in t- US in q to oj ! + >to to # fO * 4m >H St 4 * * # * * * * * * * m m *m *to + *m wt tO in z uj X im +r. !W 4 *4 I CO 4 4 4 14 U i ru * OJ + Si hi U * tc < # * * * * m ro io o dr ro m *o r> c JO DUP050310156 W --m <a< wISw ++ + a a o. !UI Ui kl a ec a a m as 2 a. \a W 1{ -aj _A U r\ IR *T LEAD Q / / q X J STUDY STUDY RESPONSE 11 PAGE ______ ____________________________________ ________________ EXPECTED MEAN SQUARE TABLE ....... ................... s zu r * / zQ v \ r X\ t Xz / x / * t / q ) / \ squ\ r / i i i! i i; i i' ( !1 :i i; DUP050310157 i : r RAT t-EAD Q / / q X J s t u q y STUDY I r / s z s / u \ J/ *** *** < <o Coii*cDr a. 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CS N. <\i CO ClLC <-4 XvO >tl rH O ~2 I-- - < a: c cou**c_ v<O**** ** *4 O N36874.12 DU PO 50310171 at if) z o H 04 K H< Id 02 <n O 2: U. in a. z </> < Id 02- Id a H -j Vo oz J3- m HO z > in a Id => O i- a to ' * X zH *- e Q H- Ui < lit Z lL. < a < H* < I-d4 a KC- D IL X Hz 0006C HOPioNC o :, oO Ioaf) JO 0J:O0I H tC-M **t:*0 ^ c0 c H - c? 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RESPONSE 12I RAT LEAD FEEDING STUDY STUDY in CM ooQ n X) CM oo 10 in CM ^oo in CM fooO CM in *) oo in in CM oo m CM ooo CM m <M o o o 0 CO CM C in in in in in in mo oO' CM CM CM G DUP050310179 K \ t . / \ q Q / / q X J s t u q y st uqy I r / s z s / IS q\ t \ p a g e 10 . / v/ . s ) u ) . / r , Q \ * t zr : ** ** ' ** * Kz q\ t \ / x \ q / q, r zw u ) . / K q( I / t XQ X* \ t Xz ; X u t LOS LIVER PB oH o oo K Cst tti i o a in O CO o c3 <\i to m o <i JT v0 431 O X a eg zX <\' O K)lO O a 4- *- X <D tn it to X ca x IT X *4 H X X XX o cjJ O ca o ea o <a o ea o Oi} 4*0 o ca o X r1 01 o o oo oo oo * if) in r** TO CNJ CJ to * in II i<- It <2 2X zWXMcoUScaJ: I! a: t3ot ( i/i at oQ H cc O AC Uw < K+a' O<*- < UJ U_J;a a iiJ UJ us h =5 3. xZ c V 7Oa QO UT z< * a. x KU oL. . uo. 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K<'XWwa Xui z(0 CJ:U- Q - XiZ x v* QCOlUQ=c h Z<:* l/T J1 (fZ<--ft i(f. t io^r miOn i c* vtvi * wZ Ui f4 Vi - CC u<-Ji J^ U) uut. uZz< ft' -U<1 if xU ;i Vi j LEAST SIGNIFICANT DIFFERENCE (LSD) s 95S5 CONFIDENCE L IM IT S = STANDARD ERROR OF A MEAN = l=flOK zDOty><4\j <M0 cOr lAlKfltifo) hMftIO H d> IO IK K v> o o r* I*-*- o <vi & cOulrOurO^ lwfltOr* fou >*K owe^o e^3 o\O* ccifolooom*o oCV K-*3mITSoC Ksr) w^soortvcvio 3- *o j _j Ui ui >> ui Ui .j -i CO fi. 03, 0. O O SO3;. oO* # lo3O DUP05031 0196 11.3057 22.3278 STANDARD ERROR OF THE DIFFERENCE BETWEEN TWO MEANS. JE.........1 5 .9 8 B 6 31.5763 I.: # 'S KAT LEAD FEEDING STUDY STUDY I RESPONSE 12_____________________ ___________________PAGE N* i *) r- o. CM <0 co in I**"* CO O <Ui * f- to KJ ** * W - OJi - CM; O W lrO* Vz) I2 in m <* o ' i<onr ; [0 jS m .>M-JUO. 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