Document kD8JwXOQb2rMX3y8Or4m840GO

linlo*tr j* 1 i_ ....... ,_ jrii____________ _ j ri.. _SKLrh^jJ).jl 245 ExUmsivc Permutitiu d*:y in W,pfirin S.*i|inm Circulation .12,"VVJ Ti~(T)T*~ " " " s * Ada,n* >d D. J, P*#| j`./;|... &T. mcmbrtnN with cortict tion of this tatlons foil* ulitle, invulvtng (he skin end mus^ ................ .. The lustuns dippfikr w.th `A'.irfuri.i ,<Miium. Upon . 'I'li- |vt>:n had no allergic tnanif*k*' Mrd, Assn. J, Abu,' ' ; An ummiai occurrence ot Spocotrlchoau. Arch, Dermatol. fl, ?7Q {<5c;. IShCTjT laminated with Sp^r^trirhum scLcncM*. '.(I J. D. Jtobhine. -.j or:irru>l ir. a ({roup uf Mexican* fr^ ' had !**- m (melted in n native unit, f!ilt - i, Occ, Med. Ahai,, *y 1 b'4 ffd ini Mj Ni m4 iO> exj jiii tl f futf CHEMICAL HAZARDS i *0 S/ft AAn 247 Poisoning by Nitrous Gases. A. Propst, -Wien. mad. Wocbschr. lift, D9l-5"b 'July 9. 1960). Carman. Poiaoning by oxides o( nUroger. --NO|. NjO,, NO and NjOj^and also by the forma* j, *.v. tion of nitrous and nitric acids may bu a risk to worker* in many industries. Numerous fault, ties in industrial workers fc.ive bc<-n r'/porred in tbs literature, Opinions on the toxicology el these substances arts not in entire arc *rd, Sonvt nbserver* consider that the chiof effect is v ' the pulmonary system througn the inca! t.rrr.u::o. of nitric acid which causes pulmonary eden., but others tako the view that a general svnoniic pMscninf, is brought about by the formation e: V**' nitrite, -ThU paper contains a detailed report of ft man *fcd 45 years who was engaged at a . /V-; steel works in cleaning our a dr<iinjt p:i uhich containsd some steel piute, with nitric acid /r.*,'! and additions of salt and sulfuric acid. .A;rer ;>* end of Ms shift he was taken 111 with giddi* . *.*. ness and some difficulty of breathing 'ni cr'uf.h. His condition ueturiorated rapidly and he died after 3 days from pulmonary edema. Thor-i % full account Of the post-mortem flndiagi. ly.V'.j including photograph* of the njcj'n**o;n* appearincue ui the lung and the results of epectro- - photometric examination of Mood raker, fr-.urt th: h.:?rt, The chief toxic change# were found u be those of local pulmonary irritation caused by the 'urination of nitric acid. Evidence of ty. temic poisoning, however, was found in the gunu-al dilatation of blood vessels, blood stasis 1 and fatty changes in the liver which rc-onlted from the formation of methymoglobin, nitrogen oxide hemoglobin and nitrite demonstrated by sytuti'viphotomatry, -- Boil. Hyg, V$ 7-V? 248 Bone-Marrow Activity and Erythrocyte Destruction in Chronic Cadmium Poisoning. Studies ' with Fe-59 on Rabblta. M. Dcr'ln and l., Friher*. Arch, Environmental Health J, 47d-4M*< {Due. *`.'001. \',,r* Thla investigation showed ha; accelerated destruction of the erythrocytes and ds >; fielency of iron in thu bone-marrow coiiiribute to (he aneicia of cadmium poisoning in additlos to the earlier demor-tirntt-d increase m ti.u volume of V.uoJ plasma, No evidence was found .>** for diminished bone-marrow activity -v.';;, vui<uct to .myth* upcie sis. Some of the observation suggested increased bene-marrow actlvr.* . Tn 5ife span of the erythrocytes was no* in cseeniial degree attributable to tuxir ,,ft,iun.: m> ervihrypuiesle. The author#1 studies dtf not elucidate whether the Iron dcficitmcy in thu bwic-m;.rrov is caused by increased ulUUatle- . ' of iron as a result of thn intunsifiod erytnrocyte ik-strucum* and consequent lose of iron or by ` *' disturbance of the rne(.t.a<Msn* for transportation i>f Iron. It was demonstrated, however, tbtt such disturbance in iron tr^/sj*onation was not siuiatrtl l.et*vvvi: the blood and the bone man*' -- Authors' conclusions ' 'J. intr avepuit leai wha heat mot tern Mlc av> with Mlc and Jsct tallt mar Jos* non lead JM Dot You coat wifi pait youi scr. til Pa; Met d#v, fact