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WM> AR226-2020 ODf'mil WasliingionWnita P. 0. Boi 12)7 Patettliig. VKV26102-1217 CC: A. J. Playtis TO: BENJAMIN RAMIREZ, M.D. HR N11498 - NILHIN6TON FROM; Y. L. POWER. M.D. -\ ^ MASHIM6TOH WORKS v November 3, 1993 REVIEW OF C-8 AND RECOMMENDATIONS C~8 exposure has been extensively monitored at Washington Works since the late 1970's. This has Included both biological/blood monitoring and air monitoring. The results of these surveys were summarized by Howard Smith In March 1990. I have Included a summary for your review. As a consequence of this summary, Washington Works continues to monitor air exposure of C-8 and offers on a voluntary basts to exposed employees a blood determination of their C-8 levels. In 1993, only 13 employees volunteered to have their Mood checked for C-8, ItAn epidemiology study on employees exposed to C-8 was completed in 1980. compared liver function tests between exposed and non-exposed employees. The study concluded as follows; "The data provided no conclusive evidence of occupational-related health problems among workers exposed to C-8." However, the summary recommended continuing survey of liver function tests which were automatically obtained on periodic physicals. For several years, I checked liver function tests of employees with the highest C-8 levels. I found no significant elevations of liver functions* After several years, I stopped this study because I could find no evidence of any liver disease. I am unaware of any cases of severe liver disease at Washington Works who were exposed to C-8. Washington Works has markedly reduced.. .--- ^^vswy exposure to C-8 by various engineering controls such as wsswX^Sf C-8 from the Pine Powder dryers and the use of liquid C-8 solution Instead of the dry chemical. in summary, I believe C-8 exposure is not causing any significant affect on the livers of Washington Works' employees. X would, however, recommend that we follow screening procedures as outlined by Howard Smith in yi of his "Review of Washington Works C-8 Data - Personnel Air Monitoring and Blood Data". I would also recommend doing liver function tests at this time to discover any potentially unknown liver toxicity. The present cost of C-8 blood determinations is between $100-200; therefore, the addition of liver function tests would add very little to the cost of this program. I have discussed this proposal with both Tony Playtis, our Occupational Health Coordinator, and the Involved areas and have received their concordance, YLP:mah Attachment Doc. 015771 E. I Hu Pant da NElmnitf 3ftd Compiny Q ftitltil on flEtidnl Pwi EID080050