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PART B BUDGET PROPOSAL
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RESEARCH TECHNIQUES AND METHODS FOR DETECTION AND PREVENTION OF CARCINOGENESIS IN INDUSTRIAL WORKERS
UNIVERSITY OF LOUISVILLE CANCER CENTER
LOUISVILLE, KENTUCKY 40201
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BUDGET SUMMARY
I. CLINICAL IMMUNOLOGY Personnel Supplies and Expenses
II. CLINICAL BIOCHEMISTRY Personnel Supplies and Equipment
III. CLINICAL BIOCHEMISTRY Personnel Supplies and Equipment
IV. CLINICAL PATHOLOGY Personnel Supplies and Expenses
V. MICROBIOLOGY Personnel Supplies and Expenses
VI. CHEMISTRY Personnel Supplies and Expenses
VII. PATHOLOGY Personnel Supplies and Expenses
Year
2
Year
3
30,605
31,523
:19^441*" 1 . 21,371
23,225 13,075
23,922 14,373
" * '
*.
8,900 8,800
* : *
9,476 8,690
. ----
.7,735
8,508
15,160 12,400
16,747 11,500
11,100 ' 16,452
.
11,845 17,657
"1.
13,990 7,200
14,719 7,590
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VIII. FRINGE BENEFITS
IX. TOTAL (Personnel and Expenses include fringe benefits)
X. INDIRECT COSTS
TOTAL
Year 2
(11,033)
188,083
Year 3
(11,596)
197,921
59,765
62,813
247,849
260,734
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BUDGET M.C.A. PROPOSAL
CLINICAL IMMUNOLOGY H. Philip Fortwengler, Investigator
A. Toxicity/Tumorgenecity Study
1. Personnel
a. H. Philip Fortwengler, MS b. Michael Dever, BS
Research Technician c. Linda Smith, BS
Research Assistant
2. Supplies and Expenses
a. Animals, 300 per year b. Animal Maintenance c. Cell Culture Reagents d. Sterile Culture Flasks e. Chemical Reagents f. Needles, Syringes g. Sterile Cell Culture,
Disposable Plastlcware h. Miscellaneous Expendables
SUBTOTALS
B. Inmmnocompetence Study
1. Personnel (No additional cost)
2. Supplies and Expenses
da Lymphocyte isolation reagents
b. Cell culture media c. 3H isotopes d. Scintillation reagents e. Miscellaneous reagents.
glassware
SUBTOTALS
Year 2
15,500 9,305 5,800
30,605
1,100 1,195 1,300 1,000
500 300 - 900 300 6,595
1,500 500 450
1,100 250
3,800
Year 3
15,965 9,584 5,974
31,523
1,210
1,315 1,330 1,100
550 330 990 330 7,155
1,650 550 495
1,210
275 4,180
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C. HL-A Tissue-Typing
1. Personnel (No additional cost)
2. Supplies/Expenses a. Hamilton syringes b. Tissue-typing antisera and plates c. Miscellaneous reagents, glassware
SUBTOTALS
D. LAI Test for Angiosarcoma
1. Personnel (No cost)
2. Supplies and Expenses a. Cell cultures b. Cell maintenance c. Miscellaneous reagents, glassware
SUBTOTALS
E. Xeroxing and publication costs
YEARLY TOTALS
II. CLINICAL BIOCHEMISTRY - ENZYME Julie T. Du, Ph.D., Investigator
A. Personnel
1. Julie T. Du, Ph.D. 2. Ruth Shelton, MS
SUBTOTALS
B. Supplies and Expenses
1. Laboratory Supplies a. Enzymes b. Radioactive
SUBTOTALS
Year 2
Year 3
500 5,300
300 6,100
550 5,840
330 6,720
250 1,346
1,100 2,696
250
266 1,590
1.210 3,066
250
50,046
52,894
13,225 10,000
23,225
13,622 10,300
23,922
1,100 979
2,079
1,200 1,078
2,278
.
.
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Animal Expenses a. Animals b. Animal care
1. Short term (200) 2. Long term (300)
SUBTOTALS
YEARLY TOTALS
Year 2
Year 3
1,350 1,920 7,726
10,996 36,300
1,485 2,112 8,498
12,095 38,295
III. CLINICAL BIOCHEMISTRY Charles E. Kupchella, Ph.D., Investigator
A. Personnel 1. Charles E. Kupchella, Ph.D. (No cost) 2. Leslie Caine, Procurrent Technician
8,900
SUBTOTALS
8,900
B. Supplies and Expenses 1. Lab/supplies/chemicals 2. Enzyme preparations 3. Glassware 4. Equipment maintenance 5. High pressure liquid chromatography columns
2,900 600
1,550 ' 350
1,500
- SUBTOTALS
6,900
C. Computer
11,000
D. Travel
900
YEARLY TOTALS
17,700
9,476
9,476
3,590 600
1,200 350
1,050 6,790 1,000
900 18,166
CLINICAL PATHOLOGY G. Randolph Schrodt, M.D., Investigator
A. Personnel 1. G. Randolph Schrodt, M.D. (No cost)
B. Supplies and Expenses 1. Lab materials 2. Chemicals 3. EM preparation and tissue storage material 4. Photography equipment and supplies
YEARLY TOTALS
2,550 650
1,435
3.100 7,735
2,700 800
2,508
2,500 8,508
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V. MICROBIOLOGY Uldis N. Strelps, Ph.D., Investigator
A. Personnel 1. U. N. Strelps, Ph.D. 2. Research Technician 3. Research Assistant
SUBTOTALS
B. Supplies and Expenses 1. Media 2. Glassware 3. Isotopes 4. Equipment maintenance 5. Publishing costs
SUBTOTALS
C. Travel to national meetings to consult with experts in the field
YEARLY TOTALS
Year 2
Year 3
2,000 7,500 5,660
15,160
2,000 8,087 6,660
16,747
4,500 2,000 3.000
500 1.000
11,000
5.000 1.000 2,100
600 1,200
9,900
1.400 27,560
1.600 28,247
CHEMISTRY John L. Wong, Ph.D., Investigator
A. Personnel 1. John L. Wong, Ph.D. (No cost) 2;\ Joseph P. Joseph, Ph.D. Post-doctoral 3. Research Assistant
SUBTOTALS
B. Supplies and Expenses 1. Chemicals, VPC, HPLC supplies 2. Glassware 3. Lab supplies 4. Publication costs 5. Equipment maintenance
SUBTOTALS
C. Travel to meetings to consult (for 2)
YEARLY TOTALS
8,600 2.500
11,100
9,000 2,845
11,845
3,500 3.800 3,400 2.800
552
14,052
2,400
3,600 3,700 3,605 3,000
752
14,657
3,000
16,452
17,657
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VII. PATHOLOGY Enrique Espinosa, M.D., Investigator
A. Personnel 1. Enrique Espinosa, M.D. (No cost) 2. Virginia Ford, B.A. Research Assistant 3. Janice Gettelfinger Part-time Clerk-Typist
SUBTOTALS
B. Expenses and Supplies 1. Supplies/expendable 2. Rabbits, purchase and maintenance 3. Equipment maintenance A. Publication costs
SUBTOTALS
Travel to other laboratories for consultation (2 trips)
YEARLY TOTALS
Year 2
Year 3
9,330 4,660 13,990
9,980 4,739 14,719
3,300
2,200 500 600
6,600
3,490
2,300 500 650
6,940
600 21,190
650 22,309
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ADDITIONAL BUDGETARY JUSTIFICATIONS
In the individual budget summaries of each proposal, there will be noted an 18 percent increase in budgetary personnel costs and a 12 percent increase in the cost of supplies and materials. This con stitutes an over-all increase in the budget of approximately 16 percent. This increase in both personnel and supplies budgets is totally a reflection of inflationary costs and is not an increase in actual fund requests.
The major increase in the budget is in indirect costs. The University overhead cost is based on a fixed value of 65 percent of wages and salaries. From these Indirect costs comes the physical and structural support from the University to the investigative projects. In addition, this year this includes the availability of a Type 3 exposure facility and its safety and operational personnel. This facility is under construction and was funded by the University through general University funds, and its operation and maintenance will be supported by general University funds. The indirect costs reflect the depreciation costs for the availability of these facilities. In the absence of such indirect costs, the direct charges to various investi gators and projects for housing hereof and exposure of experimental animals would be substantially and significantly increased.
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