Document k9E33qp5y0Q3pNnXkgo77NEg0
Copies to:
AR226-2752
E. I. du Pone de Hemours and Company
Haskell Laboratory for Toxicology and Industrial Medicine
Elktun Road, Newark, Delaware 19711 HASKELL LABORATORY REPORT NO. 636-79
Material Tested
O^canuic Ac id, PentaJecarluoro-, .-^iniuniuni Salt:*
Haskell
No.
12,037
Other
Study Initiated/
I; Codes1
Completed
8/15-8/17/79
I
Material ^Plas
Department, Wash
SKIN IRRITATION TEST ON RABBITS
Pt-oeedur^; Six reaLe albino cabbies were. clipped -free of hair on the trunk and lateral areas and plac Doses of 0.5 gm solid test material were. applied as an aqueous paste to Intact skin under 1--1/2" x 1squares. Rubber sheeting was then loosely wrapped around the trunk and secured with adhesive tape.
rabbits were removed from die stocks, the patches taken off and the reactions observed. Observations
4d hours.
Results:
24-Hour Observation
Erythema
Edema
48-Hour Observation
Erythema
Edema
Moderate 3/6
Mild
3/6
Mild 1/6
Slight 3/6 None 2/6
Moderate 2/6
Mild
3/6
Slight 1/6
Mild 1/6 Slight 2/6 Hone 3/6
S" Summary: Octanoic Ai;id, Pisntadecafluoro-, Ammonium Sait|J1BHBjcaused mild to moderate skin irrita
aliyhc ti^nodiirace irritation in 48 hours when tested onT-he shaved intact skin of rabbits under sem ^^BBB|uy caiidri mild skin irritation upon repeated contact. Good industrial hygiene prac
iiii.iiiuiiza rikin contact.. In tlie event of any skin contact, wash thoroughly with soap and water.
bi-'E:si;g L)-ittf [asu<2d:
October
1979
A Report by:
^ ^
Doris F Toxic
Approved by;
Gerald
Chief, Acute Inv
Company Sanitized. Does not contai