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. AR 226 - 0912 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) IesTsuestan 00c 000E 00 Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FX-3103. (1Octanesulfonic acid) (CAS # 2795-39-3). Remarks: The 3M production lot number was not noted. Thetestsample is FX-3103, 3%. Current information indicates it is a mixture of 0.96%PFOS, 20% diethylene glycol butyl ether, 50.56% water, 15% ethylene glycol, 4.32% sodium octyl sulfate, 6.0% polyoxyethylene monooctylphenyl ether, 2.5% propane sultone foamer, 0.5% sodium nitrate, 0.06% sodium lauryl sulfate, and 0.1% benzotriazole. - The following summary applies to a mixture with incompletely characterized concentrationsof impurities. Data may not accurately reflect the toxicity of the fluorochemical component of the test sample. METHOD: Method: Not given. Type: Static acute GLP: No Year completed: 1985 Species: Daphnia magna Supplier: In-house cultures. Originally obtained from U.S. EPA-ERL, MN. Analytical monitoring: Temperature, pH, and dissolved oxygen. Exposure period: 48-hours Test organism age: <24 hours old Statistical methods: ECs values calculated using logistic regression methods (probit analysis). Test conditions: Dilution water: Carbon-filtered well water. Dilution water chemistry: Not given. Duluth, Lighting: Not given. Stock and test solution preparation: A primary stock solution was prepared by dissolving 1000 mgoftest substance in 500 mL water. Exposure concentrations were prepared by additionofstock solution to each vessel. Exposure vessels: 250 mL glass beakers containing 200 mL exposure ~~ solution at adep oft6chm. Number of replicates: 2 Number of daphnids per replicate: 10 Number of concentrations: five plus a blank control Water chemistry during the study: 002968 pH range (048 hours): 87..18-88..12 ((c1o0n0tr0olmge/xLpoesxuproes)ure) Temperature range (048 hours): 22 C Dissolved oxygen range (0-48 hours): 8.99.3 mg (control exposure) 7.0-9.3 mg/L (1000mg/L exposure) RESULTS Nominal concentrations: Blank control, 100, 180, 320, 560, and 1000 mg/L. Element values: 48-hour ECs = >1000 mgiL Element values based on nominal concentrations. Remarks: Testing was conducted on a mixture as described in the Test t`hSeubfsltuaonrcoechreRmmiacarlksprfoieplodr.tiTohnealvoanleu.es reported apply to that mixture and not CONCLUSIONS The test substance 48-hour ECso was determined to be >1000 mg/L. Submitter: 3M Paul, Minnesota, Company, 55133 Environmental Laboratory, P.O. Box 33331, St. DATA QUALITY Rmeeltiahboidlitfyo:lloKweidi.misTchherasntkuidnygl=ac3k.s iSntfuodrymaltaicoknsodnespcurriipttyioofntahnedtersetcosrudbsstoafnce and analytical solution. confirmationofthe amount of fluorochemmical proportion in REFERENCES ~~~ 00000 TSth.isPasutlu,dyMNw,asLacbonRdeuqcuteesdbtyntuhmbee3rMC1C1o1m1p-a1n,y1,8E5n.vironmental Laboratory, -- TH--------i ------------------------------------ Last changed: 6/26/00. 002970 AQUEANTVIICROTNMOEXNITCAILTY LADBAOTRAATSOHREYET RC ENLL, TEST eHBueAyre Sa. cmc TESTED SX=Z/0S 5% LOT TEST ORGANISH 203014042TpE 50 SOURCEELK SETALi =. l TE REC'N_LLL AGE OF TEST ORGANISMS2:4< hrs. old instars (neonates) HO. ORGANISMS PER TREATMZCENT TEST VESSEL: 250m Pyrex glass beaker TEST SOLUTION VOLUME: 200ml BEPTIR 6m TIME STARTER TL 0ATe STARTELL/LL/vBatSecormisrens ZEA _DILUTION WATER Carbon-filtered well water (Temp. 2.2 C, 0.0.2.5 pom. PH_./) RE (95% Confidence Limits) A EPEr PT TEST [miei|morar 24 fours 18 Hows P lNO.| me ot |nda ded| Daf eeoadTE ITlopTm|e ,Deadbt h7p)e 4 hzlieolieTo TT1'o bled] Sg h=slol=z 0TTT0 Bis =z Welsolaef0 TT 0 ET ds 5 hshioTplziTcToTo Balu) g C1TT T1171 11] 2 (T L TTT T TT] CInfellsspate = FS RS ers2K RS COMMENTSX:72 4310 1 Seta edi. Lau Auld F 2A =pe 4 fovsuese Viper 4 400 furl = 2 ot z= SECONDARY 1 EFFECTS, omm eo n| ES i 11 1 11 tr r r 1 "11 C1 1 1 1 002971 AQUATICTORIGITY DATASHEET w=, TEST TYPE, fautAder gmp vemen Teste) 2X SPS SYD on TESTORL dlapap SORCELSEPI ETovate won__lades AGE OF TEST ORGANISHS:424 hrs. old fnstars (neonates) AD. ORGANISMS PER TREATMENL_Zc) TEST VESSEL: 250ml Pyrex glass beaker TEST SOLUTION VOLUME: 200mlSHR bcm TINE STARTER SUC3tf DATE starter24/85onecomnerencRlB/85 DILU= TION WATERe Carbon-filtered well water (Temp._22, 0.0.2.3ppm, pH_8,/) VESwSELieconnc. | Eales amount | Total vo. Jp Pah Total Yo.[of [0.0 aloo] TTT 0kil a zlis|o ol TTw1's Bed 2 al=olol o TTT 5hiss > Alsalse 0TTT0 boa 3 le=shioonlool 2 TT15balyz] > CTTT TTT 171 = NN SNA A I UInft& flataels Rms 7 /RETogPIRES] OT fmem [i ig" COMMENTS: Se Zor 010K Syn" pao spe]: 100 meg Csoatan [Lind chil: & Ldopht dent FHPII. Solubide In WBForcot cquitiea nlite, SECONDARY EFFI 1 1 I 1] 1 1 TT1 1 11 1 1 11 002972 FAVIRORMENTAL LABORATORY Co: y 3 TALE 1. suuRT or Acute Toxiewrt or SALR/0R Zh (Liht Leh) To DAPENIA NAGA DNDER__ S707 Exposuz conprrions!) : CRENICA(LSCHONCENTRATION sercens worzaLITY 20-m. nem. contaon 00 80 20 50 Joon 20 4s awco y, (95C2aenconrromicy Lntrs2) > 1000 >loco 2 1) DFaetpaitweeartee.avAersfgeersalofoftwtowernetpylidcaapthiaoindss vfeorresecehdcopnercenctornacteinotnratviiotnh.ten (10) daphuids per A oy, values were catentated urtog loptatic repression methods (Frobit Analyste). =3 y